Disease associated with RCD disease & gene list




BRCA specific anoikis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 BRCA anoikis CAV1 caveolin 1 13.73 10.3 -0.41 0.0 0.0 100.0 Detail
2 BRCA anoikis NTRK2 neurotrophic receptor tyrosine kinase 2 12.98 8.81 -0.56 0.0 0.0 92.83 Detail
3 BRCA anoikis PDK4 pyruvate dehydrogenase kinase 4 12.97 8.99 -0.53 0.0 0.0 92.47 Detail
4 BRCA anoikis E2F1 E2F transcription factor 1 5.95 8.43 0.5 0.0 0.0 88.43 Detail
5 BRCA anoikis DAPK2 death associated protein kinase 2 9.0 7.85 -0.2 0.0 0.0 67.19 Detail
6 BRCA anoikis BRMS1 BRMS1 transcriptional repressor and anoikis regulator 8.97 9.91 0.14 0.0 0.0 67.15 Detail
7 BRCA anoikis PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 9.8 8.98 -0.13 0.0 0.0 57.03 Detail
8 BRCA anoikis SRC SRC proto-oncogene, non-receptor tyrosine kinase 9.35 10.17 0.12 0.0 0.0 53.85 Detail
9 BRCA anoikis PTRH2 peptidyl-tRNA hydrolase 2 8.12 8.89 0.13 0.0 0.0 53.02 Detail
10 BRCA anoikis CHEK2 checkpoint kinase 2 6.93 7.81 0.17 0.0 0.0 50.41 Detail
11 BRCA anoikis BMF Bcl2 modifying factor 8.47 9.19 0.12 0.0 0.0 47.2 Detail
12 BRCA anoikis ITGB1 integrin subunit beta 1 14.21 13.51 -0.07 0.0 0.0 46.36 Detail
13 BRCA anoikis SNAI2 snail family transcriptional repressor 2 9.51 8.46 -0.17 0.0 0.0 44.66 Detail
14 BRCA anoikis BCL2L1 BCL2 like 1 10.9 11.33 0.06 0.0 0.0 43.28 Detail
15 BRCA anoikis NOTCH1 notch receptor 1 10.58 9.95 -0.09 0.0 0.0 40.03 Detail
16 BRCA anoikis TLE1 TLE family member 1, transcriptional corepressor 10.2 9.31 -0.13 0.0 0.0 39.41 Detail
17 BRCA anoikis TFDP1 transcription factor Dp-1 10.37 10.79 0.06 0.0 0.0 32.87 Detail
18 BRCA anoikis MCL1 MCL1 apoptosis regulator, BCL2 family member 13.51 13.11 -0.04 0.0 0.0 24.41 Detail
19 BRCA anoikis SIK1 salt inducible kinase 1 10.82 10.01 -0.11 0.0 0.0 23.56 Detail
20 BRCA anoikis PTK2 protein tyrosine kinase 2 11.07 11.41 0.04 0.0 0.0 21.76 Detail
21 BRCA anoikis STK11 serine/threonine kinase 11 9.48 9.86 0.06 0.0 0.0 20.95 Detail
22 BRCA anoikis IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 8.22 8.55 0.06 0.0 0.0 14.59 Detail
23 BRCA anoikis BCL2 BCL2 apoptosis regulator 11.09 10.18 -0.12 0.0 0.0 13.56 Detail
24 BRCA anoikis ANKRD13C ankyrin repeat domain 13C 9.3 9.14 -0.02 0.0 0.0 5.29 Detail
25 BRCA anoikis CRYBA1 crystallin beta A1 0.15 0.14 -0.05 0.89 0.89 0.0 Detail
26 BRCA anoikis ITGA5 integrin subunit alpha 5 10.86 11.02 0.02 0.08 0.09 0.0 Detail
27 BRCA anoikis MAP3K7 mitogen-activated protein kinase kinase kinase 7 9.62 9.45 -0.03 0.0 0.0 0.0 Detail
28 BRCA anoikis MYBBP1A MYB binding protein 1a 9.9 10.04 0.02 0.2 0.21 0.0 Detail
29 BRCA anoikis TSC2 TSC complex subunit 2 10.69 10.72 0.0 0.82 0.85 0.0 Detail

Ensemble learning for BRCA based on specific anoikis gene regulaors.