Disease associated with RCD disease & gene list




BRCA specific cuproptosis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 BRCA cuproptosis CDK1 cyclin dependent kinase 1 6.5 9.56 0.56 0.0 0.0 100.0 Detail
2 BRCA cuproptosis CDKN3 cyclin dependent kinase inhibitor 3 4.29 7.19 0.75 0.0 0.0 98.55 Detail
3 BRCA cuproptosis AQP1 aquaporin 1 (Colton blood group) 13.7 11.28 -0.28 0.0 0.0 98.37 Detail
4 BRCA cuproptosis CAT catalase 12.48 10.57 -0.24 0.0 0.0 97.98 Detail
5 BRCA cuproptosis FOXM1 forkhead box M1 6.17 9.6 0.64 0.0 0.0 97.96 Detail
6 BRCA cuproptosis PRC1 protein regulator of cytokinesis 1 7.53 9.93 0.4 0.0 0.0 96.57 Detail
7 BRCA cuproptosis ARF1 ADP ribosylation factor 1 12.79 13.76 0.11 0.0 0.0 96.51 Detail
8 BRCA cuproptosis ANLN anillin, actin binding protein 6.03 9.34 0.63 0.0 0.0 96.49 Detail
9 BRCA cuproptosis AOC3 amine oxidase copper containing 3 12.86 9.13 -0.5 0.0 0.0 95.88 Detail
10 BRCA cuproptosis ATP6AP1 ATPase H+ transporting accessory protein 1 11.4 12.5 0.13 0.0 0.0 94.64 Detail
11 BRCA cuproptosis EGFR epidermal growth factor receptor 10.72 7.34 -0.55 0.0 0.0 93.81 Detail
12 BRCA cuproptosis SNCA synuclein alpha 7.18 5.13 -0.48 0.0 0.0 91.94 Detail
13 BRCA cuproptosis YAP1 Yes1 associated transcriptional regulator 12.31 11.01 -0.16 0.0 0.0 91.62 Detail
14 BRCA cuproptosis PRNP prion protein (Kanno blood group) 12.19 10.55 -0.21 0.0 0.0 91.31 Detail
15 BRCA cuproptosis NNAT neuronatin 7.7 3.79 -1.02 0.0 0.0 91.3 Detail
16 BRCA cuproptosis AP1S1 adaptor related protein complex 1 subunit sigma 1 8.76 9.96 0.19 0.0 0.0 90.56 Detail
17 BRCA cuproptosis CIT citron rho-interacting serine/threonine kinase 6.62 8.59 0.38 0.0 0.0 90.55 Detail
18 BRCA cuproptosis TANK TRAF family member associated NFKB activator 10.71 9.63 -0.15 0.0 0.0 88.36 Detail
19 BRCA cuproptosis DPYD dihydropyrimidine dehydrogenase 10.05 8.48 -0.24 0.0 0.0 88.35 Detail
20 BRCA cuproptosis COX7A1 cytochrome c oxidase subunit 7A1 8.94 6.41 -0.48 0.0 0.0 88.19 Detail
21 BRCA cuproptosis MRPL14 mitochondrial ribosomal protein L14 8.58 9.78 0.19 0.0 0.0 87.92 Detail
22 BRCA cuproptosis TARS2 threonyl-tRNA synthetase 2, mitochondrial 8.81 9.72 0.14 0.0 0.0 87.56 Detail
23 BRCA cuproptosis HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 13.3 13.88 0.06 0.0 0.0 87.56 Detail
24 BRCA cuproptosis MRPL17 mitochondrial ribosomal protein L17 9.23 10.11 0.13 0.0 0.0 87.33 Detail
25 BRCA cuproptosis CNN1 calponin 1 11.35 7.96 -0.51 0.0 0.0 87.11 Detail
26 BRCA cuproptosis SLC25A39 solute carrier family 25 member 39 10.37 11.44 0.14 0.0 0.0 87.09 Detail
27 BRCA cuproptosis FAM96A cytosolic iron-sulfur assembly component 2A 8.8 9.59 0.12 0.0 0.0 87.04 Detail
28 BRCA cuproptosis MT1M metallothionein 1M 7.04 4.31 -0.71 0.0 0.0 86.98 Detail
29 BRCA cuproptosis ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 10.41 11.17 0.1 0.0 0.0 86.97 Detail
30 BRCA cuproptosis PGP phosphoglycolate phosphatase 7.58 8.75 0.21 0.0 0.0 86.66 Detail
31 BRCA cuproptosis SOD3 superoxide dismutase 3 10.45 7.62 -0.46 0.0 0.0 86.45 Detail
32 BRCA cuproptosis UBAP2L ubiquitin associated protein 2 like 11.4 12.11 0.09 0.0 0.0 86.36 Detail
33 BRCA cuproptosis AOC2 amine oxidase copper containing 2 6.11 3.64 -0.75 0.0 0.0 85.93 Detail
34 BRCA cuproptosis CUTC cutC copper transporter 8.74 7.77 -0.17 0.0 0.0 85.89 Detail
35 BRCA cuproptosis DNA2 DNA replication helicase/nuclease 2 5.57 7.22 0.37 0.0 0.0 85.66 Detail
36 BRCA cuproptosis MRPL13 mitochondrial ribosomal protein L13 8.79 9.81 0.16 0.0 0.0 85.32 Detail
37 BRCA cuproptosis MT1X metallothionein 1X 10.87 8.67 -0.33 0.0 0.0 85.31 Detail
38 BRCA cuproptosis HNRNPU heterogeneous nuclear ribonucleoprotein U 13.16 13.65 0.05 0.0 0.0 83.57 Detail
39 BRCA cuproptosis ABCB8 ATP binding cassette subfamily B member 8 8.49 9.46 0.16 0.0 0.0 83.26 Detail
40 BRCA cuproptosis DTYMK deoxythymidylate kinase 7.88 8.92 0.18 0.0 0.0 82.4 Detail
41 BRCA cuproptosis MAL2 mal, T cell differentiation protein 2 10.88 12.4 0.19 0.0 0.0 82.25 Detail
42 BRCA cuproptosis ISG15 ISG15 ubiquitin like modifier 7.43 10.09 0.44 0.0 0.0 82.24 Detail
43 BRCA cuproptosis MRPS12 mitochondrial ribosomal protein S12 8.02 9.15 0.19 0.0 0.0 82.18 Detail
44 BRCA cuproptosis NFE2L2 NFE2 like bZIP transcription factor 2 11.72 11.09 -0.08 0.0 0.0 82.16 Detail
45 BRCA cuproptosis CSTF3 cleavage stimulation factor subunit 3 8.98 9.56 0.09 0.0 0.0 81.32 Detail
46 BRCA cuproptosis UBE2I ubiquitin conjugating enzyme E2 I 10.56 11.16 0.08 0.0 0.0 80.8 Detail
47 BRCA cuproptosis MRPS23 mitochondrial ribosomal protein S23 8.92 9.76 0.13 0.0 0.0 80.74 Detail
48 BRCA cuproptosis ACO1 aconitase 1 11.45 9.72 -0.24 0.0 0.0 80.31 Detail
49 BRCA cuproptosis FKBP4 FKBP prolyl isomerase 4 11.46 12.86 0.17 0.0 0.0 80.24 Detail
50 BRCA cuproptosis TRAIP TRAF interacting protein 5.54 6.79 0.29 0.0 0.0 79.93 Detail
51 BRCA cuproptosis TPI1 triosephosphate isomerase 1 11.95 12.77 0.1 0.0 0.0 79.81 Detail
52 BRCA cuproptosis IDH2 isocitrate dehydrogenase (NADP(+)) 2 10.51 11.78 0.16 0.0 0.0 77.82 Detail
53 BRCA cuproptosis SLC25A26 solute carrier family 25 member 26 8.82 8.25 -0.1 0.0 0.0 77.61 Detail
54 BRCA cuproptosis CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 8.52 9.32 0.13 0.0 0.0 77.52 Detail
55 BRCA cuproptosis PRDX1 peroxiredoxin 1 12.2 13.08 0.1 0.0 0.0 77.17 Detail
56 BRCA cuproptosis COPB2 COPI coat complex subunit beta 2 11.68 12.32 0.08 0.0 0.0 77.04 Detail
57 BRCA cuproptosis DLST dihydrolipoamide S-succinyltransferase 11.4 10.85 -0.07 0.0 0.0 76.98 Detail
58 BRCA cuproptosis NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 10.82 11.5 0.09 0.0 0.0 76.7 Detail
59 BRCA cuproptosis PDE3B phosphodiesterase 3B 9.69 6.28 -0.62 0.0 0.0 75.59 Detail
60 BRCA cuproptosis GGPS1 geranylgeranyl diphosphate synthase 1 9.84 10.52 0.1 0.0 0.0 75.56 Detail
61 BRCA cuproptosis RUVBL2 RuvB like AAA ATPase 2 9.82 10.76 0.13 0.0 0.0 75.48 Detail
62 BRCA cuproptosis DAXX death domain associated protein 10.28 10.87 0.08 0.0 0.0 75.31 Detail
63 BRCA cuproptosis DLG3 discs large MAGUK scaffold protein 3 9.54 10.68 0.16 0.0 0.0 75.26 Detail
64 BRCA cuproptosis DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 11.91 11.22 -0.09 0.0 0.0 75.01 Detail
65 BRCA cuproptosis CHMP4B charged multivesicular body protein 4B 11.37 11.98 0.08 0.0 0.0 74.99 Detail
66 BRCA cuproptosis NDOR1 NADPH dependent diflavin oxidoreductase 1 8.39 9.39 0.16 0.0 0.0 74.44 Detail
67 BRCA cuproptosis LIPT1 lipoyltransferase 1 7.36 6.74 -0.13 0.0 0.0 74.29 Detail
68 BRCA cuproptosis RANGAP1 Ran GTPase activating protein 1 10.38 11.29 0.12 0.0 0.0 73.79 Detail
69 BRCA cuproptosis DAPK2 death associated protein kinase 2 9.0 7.85 -0.2 0.0 0.0 73.72 Detail
70 BRCA cuproptosis VARS2 valyl-tRNA synthetase 2, mitochondrial 8.8 9.54 0.12 0.0 0.0 73.65 Detail
71 BRCA cuproptosis HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 9.82 10.6 0.11 0.0 0.0 73.62 Detail
72 BRCA cuproptosis SHMT2 serine hydroxymethyltransferase 2 9.86 10.71 0.12 0.0 0.0 73.5 Detail
73 BRCA cuproptosis OSBPL9 oxysterol binding protein like 9 11.25 10.59 -0.09 0.0 0.0 73.43 Detail
74 BRCA cuproptosis MRPS16 mitochondrial ribosomal protein S16 10.45 10.96 0.07 0.0 0.0 72.82 Detail
75 BRCA cuproptosis MRPL55 mitochondrial ribosomal protein L55 8.26 9.26 0.17 0.0 0.0 72.42 Detail
76 BRCA cuproptosis CCDC137 coiled-coil domain containing 137 7.88 8.91 0.18 0.0 0.0 71.6 Detail
77 BRCA cuproptosis BACE1 beta-secretase 1 10.47 9.73 -0.11 0.0 0.0 71.43 Detail
78 BRCA cuproptosis PPP1R15A protein phosphatase 1 regulatory subunit 15A 11.21 9.94 -0.17 0.0 0.0 70.72 Detail
79 BRCA cuproptosis TLR3 toll like receptor 3 8.42 6.94 -0.28 0.0 0.0 70.72 Detail
80 BRCA cuproptosis SRP54 signal recognition particle 54 10.01 10.56 0.08 0.0 0.0 70.68 Detail
81 BRCA cuproptosis KIDINS220 kinase D interacting substrate 220 11.53 10.87 -0.08 0.0 0.0 70.06 Detail
82 BRCA cuproptosis FADD Fas associated via death domain 8.77 9.59 0.13 0.0 0.0 70.01 Detail
83 BRCA cuproptosis NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 9.45 10.09 0.09 0.0 0.0 69.38 Detail
84 BRCA cuproptosis SDHD succinate dehydrogenase complex subunit D 10.91 10.27 -0.09 0.0 0.0 69.27 Detail
85 BRCA cuproptosis NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic 8.87 9.91 0.16 0.0 0.0 68.86 Detail
86 BRCA cuproptosis SDSL serine dehydratase like 6.87 8.11 0.24 0.0 0.0 68.76 Detail
87 BRCA cuproptosis NOP2 NOP2 nucleolar protein 8.97 9.75 0.12 0.0 0.0 68.53 Detail
88 BRCA cuproptosis SCO2 synthesis of cytochrome C oxidase 2 8.09 8.96 0.15 0.0 0.0 68.4 Detail
89 BRCA cuproptosis ISCU iron-sulfur cluster assembly enzyme 10.86 10.26 -0.08 0.0 0.0 68.28 Detail
90 BRCA cuproptosis SLC25A19 solute carrier family 25 member 19 7.05 7.94 0.17 0.0 0.0 68.24 Detail
91 BRCA cuproptosis LIAS lipoic acid synthetase 8.01 7.29 -0.14 0.0 0.0 67.86 Detail
92 BRCA cuproptosis ETFDH electron transfer flavoprotein dehydrogenase 9.5 8.63 -0.14 0.0 0.0 67.74 Detail
93 BRCA cuproptosis MMGT1 membrane magnesium transporter 1 10.13 9.51 -0.09 0.0 0.0 67.64 Detail
94 BRCA cuproptosis NDUFB11 NADH:ubiquinone oxidoreductase subunit B11 9.86 10.56 0.1 0.0 0.0 67.28 Detail
95 BRCA cuproptosis ACP1 acid phosphatase 1 10.25 10.71 0.06 0.0 0.0 67.26 Detail
96 BRCA cuproptosis MRPL12 mitochondrial ribosomal protein L12 8.81 9.87 0.16 0.0 0.0 67.12 Detail
97 BRCA cuproptosis MRPL51 mitochondrial ribosomal protein L51 10.1 10.75 0.09 0.0 0.0 66.95 Detail
98 BRCA cuproptosis SOD2 superoxide dismutase 2 12.77 11.74 -0.12 0.0 0.0 66.94 Detail
99 BRCA cuproptosis STEAP4 STEAP4 metalloreductase 11.26 9.04 -0.32 0.0 0.0 66.88 Detail
100 BRCA cuproptosis NTHL1 nth like DNA glycosylase 1 7.03 8.18 0.22 0.0 0.0 66.53 Detail
101 BRCA cuproptosis RPS25 ribosomal protein S25 13.47 12.7 -0.08 0.0 0.0 66.5 Detail
102 BRCA cuproptosis EPC2 enhancer of polycomb homolog 2 9.78 9.16 -0.09 0.0 0.0 66.48 Detail
103 BRCA cuproptosis RPUSD4 RNA pseudouridine synthase D4 9.16 8.62 -0.09 0.0 0.0 66.22 Detail
104 BRCA cuproptosis PSMA6 proteasome 20S subunit alpha 6 10.72 11.31 0.08 0.0 0.0 66.03 Detail
105 BRCA cuproptosis SDHC succinate dehydrogenase complex subunit C 10.82 11.39 0.08 0.0 0.0 66.0 Detail
106 BRCA cuproptosis SLC7A5 solute carrier family 7 member 5 8.42 10.48 0.32 0.0 0.0 65.91 Detail
107 BRCA cuproptosis BUD31 BUD31 homolog 9.62 10.17 0.08 0.0 0.0 65.71 Detail
108 BRCA cuproptosis PSMB5 proteasome 20S subunit beta 5 10.45 11.07 0.08 0.0 0.0 65.56 Detail
109 BRCA cuproptosis PGK1 phosphoglycerate kinase 1 12.33 13.0 0.08 0.0 0.0 65.44 Detail
110 BRCA cuproptosis NDUFS6 NADH:ubiquinone oxidoreductase subunit S6 8.85 9.81 0.15 0.0 0.0 65.06 Detail
111 BRCA cuproptosis CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 8.82 9.56 0.12 0.0 0.0 65.04 Detail
112 BRCA cuproptosis CDKN2A cyclin dependent kinase inhibitor 2A 5.37 7.22 0.43 0.0 0.0 64.97 Detail
113 BRCA cuproptosis ATOX1 antioxidant 1 copper chaperone 9.2 9.95 0.11 0.0 0.0 64.22 Detail
114 BRCA cuproptosis NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase 9.92 10.59 0.09 0.0 0.0 63.89 Detail
115 BRCA cuproptosis POLR2K RNA polymerase II, I and III subunit K 9.56 10.25 0.1 0.0 0.0 63.82 Detail
116 BRCA cuproptosis MRPL36 mitochondrial ribosomal protein L36 7.94 8.6 0.11 0.0 0.0 63.27 Detail
117 BRCA cuproptosis PMVK phosphomevalonate kinase 9.39 10.27 0.13 0.0 0.0 62.98 Detail
118 BRCA cuproptosis POLD1 DNA polymerase delta 1, catalytic subunit 7.88 8.85 0.17 0.0 0.0 62.4 Detail
119 BRCA cuproptosis CCDC28B coiled-coil domain containing 28B 5.43 6.56 0.27 0.0 0.0 61.98 Detail
120 BRCA cuproptosis PDZD4 PDZ domain containing 4 7.1 5.46 -0.38 0.0 0.0 61.38 Detail
121 BRCA cuproptosis CYC1 cytochrome c1 10.34 11.11 0.1 0.0 0.0 61.37 Detail
122 BRCA cuproptosis COPZ1 COPI coat complex subunit zeta 1 11.58 12.04 0.06 0.0 0.0 61.06 Detail
123 BRCA cuproptosis COX17 cytochrome c oxidase copper chaperone COX17 8.47 9.17 0.11 0.0 0.0 60.99 Detail
124 BRCA cuproptosis POLE DNA polymerase epsilon, catalytic subunit 9.39 9.98 0.09 0.0 0.0 60.44 Detail
125 BRCA cuproptosis ISCA1 iron-sulfur cluster assembly 1 9.94 9.49 -0.07 0.0 0.0 60.4 Detail
126 BRCA cuproptosis AHR aryl hydrocarbon receptor 11.57 10.61 -0.12 0.0 0.0 60.38 Detail
127 BRCA cuproptosis TAF4 TATA-box binding protein associated factor 4 8.57 9.04 0.08 0.0 0.0 60.08 Detail
128 BRCA cuproptosis SSBP1 single stranded DNA binding protein 1 9.74 10.23 0.07 0.0 0.0 59.88 Detail
129 BRCA cuproptosis MAD2L2 mitotic arrest deficient 2 like 2 8.23 8.98 0.13 0.0 0.0 59.85 Detail
130 BRCA cuproptosis CMPK1 cytidine/uridine monophosphate kinase 1 12.05 11.56 -0.06 0.0 0.0 59.24 Detail
131 BRCA cuproptosis EARS2 glutamyl-tRNA synthetase 2, mitochondrial 9.19 9.79 0.09 0.0 0.0 58.92 Detail
132 BRCA cuproptosis ABCB11 ATP binding cassette subfamily B member 11 2.39 0.86 -1.48 0.0 0.0 58.79 Detail
133 BRCA cuproptosis FDXR ferredoxin reductase 7.04 8.1 0.2 0.0 0.0 58.56 Detail
134 BRCA cuproptosis MRPL52 mitochondrial ribosomal protein L52 8.31 8.97 0.11 0.0 0.0 58.38 Detail
135 BRCA cuproptosis NAPA NSF attachment protein alpha 11.33 11.86 0.07 0.0 0.0 57.06 Detail
136 BRCA cuproptosis NDUFB4 NADH:ubiquinone oxidoreductase subunit B4 10.48 11.0 0.07 0.0 0.0 56.99 Detail
137 BRCA cuproptosis ZNF341 zinc finger protein 341 6.93 7.46 0.11 0.0 0.0 56.84 Detail
138 BRCA cuproptosis CCDC22 coiled-coil domain containing 22 8.59 9.09 0.08 0.0 0.0 56.69 Detail
139 BRCA cuproptosis NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 9.89 10.54 0.09 0.0 0.0 56.52 Detail
140 BRCA cuproptosis SLC7A11 solute carrier family 7 member 11 5.22 6.76 0.37 0.0 0.0 56.52 Detail
141 BRCA cuproptosis CMC1 C-X9-C motif containing 1 6.83 7.34 0.1 0.0 0.0 56.46 Detail
142 BRCA cuproptosis MAN2C1 mannosidase alpha class 2C member 1 10.05 9.46 -0.09 0.0 0.0 56.23 Detail
143 BRCA cuproptosis ATM ATM serine/threonine kinase 10.53 9.78 -0.11 0.0 0.0 56.04 Detail
144 BRCA cuproptosis PPAT phosphoribosyl pyrophosphate amidotransferase 8.08 8.86 0.13 0.0 0.0 55.88 Detail
145 BRCA cuproptosis UBE2D2 ubiquitin conjugating enzyme E2 D2 10.53 10.84 0.04 0.0 0.0 55.32 Detail
146 BRCA cuproptosis TPK1 thiamin pyrophosphokinase 1 6.59 5.86 -0.17 0.0 0.0 54.65 Detail
147 BRCA cuproptosis EIF4G1 eukaryotic translation initiation factor 4 gamma 1 12.7 13.11 0.05 0.0 0.0 54.35 Detail
148 BRCA cuproptosis NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial 8.71 8.15 -0.1 0.0 0.0 54.35 Detail
149 BRCA cuproptosis COPS5 COP9 signalosome subunit 5 10.02 10.49 0.07 0.0 0.0 54.14 Detail
150 BRCA cuproptosis MRPL15 mitochondrial ribosomal protein L15 9.31 9.92 0.09 0.0 0.0 53.98 Detail
151 BRCA cuproptosis NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 10.74 11.45 0.09 0.0 0.0 53.86 Detail
152 BRCA cuproptosis CLEC11A C-type lectin domain containing 11A 6.78 7.95 0.23 0.0 0.0 53.85 Detail
153 BRCA cuproptosis ALB albumin 7.19 3.96 -0.86 0.0 0.0 53.74 Detail
154 BRCA cuproptosis MTBP MDM2 binding protein 6.17 7.08 0.2 0.0 0.0 53.36 Detail
155 BRCA cuproptosis C6orf136 chromosome 6 open reading frame 136 7.48 7.96 0.09 0.0 0.0 52.95 Detail
156 BRCA cuproptosis MRPS21 mitochondrial ribosomal protein S21 9.61 10.23 0.09 0.0 0.0 52.88 Detail
157 BRCA cuproptosis MDH2 malate dehydrogenase 2 11.46 11.89 0.05 0.0 0.0 52.64 Detail
158 BRCA cuproptosis NDUFB2 NADH:ubiquinone oxidoreductase subunit B2 9.76 10.34 0.08 0.0 0.0 52.56 Detail
159 BRCA cuproptosis MRPS14 mitochondrial ribosomal protein S14 8.5 8.9 0.07 0.0 0.0 52.53 Detail
160 BRCA cuproptosis FAS Fas cell surface death receptor 8.7 7.86 -0.15 0.0 0.0 52.2 Detail
161 BRCA cuproptosis CENPW centromere protein W 6.14 7.22 0.23 0.0 0.0 52.09 Detail
162 BRCA cuproptosis SLC31A2 solute carrier family 31 member 2 9.38 8.61 -0.12 0.0 0.0 51.91 Detail
163 BRCA cuproptosis SLFN11 schlafen family member 11 9.9 8.98 -0.14 0.0 0.0 51.91 Detail
164 BRCA cuproptosis GFRA3 GDNF family receptor alpha 3 3.68 2.38 -0.63 0.0 0.0 51.66 Detail
165 BRCA cuproptosis HSPH1 heat shock protein family H (Hsp110) member 1 10.81 11.5 0.09 0.0 0.0 51.27 Detail
166 BRCA cuproptosis TMEM199 transmembrane protein 199 8.57 9.05 0.08 0.0 0.0 51.27 Detail
167 BRCA cuproptosis GSS glutathione synthetase 9.68 10.17 0.07 0.0 0.0 51.05 Detail
168 BRCA cuproptosis HSF1 heat shock transcription factor 1 10.18 10.78 0.08 0.0 0.0 50.76 Detail
169 BRCA cuproptosis YARS2 tyrosyl-tRNA synthetase 2 8.22 8.57 0.06 0.0 0.0 50.71 Detail
170 BRCA cuproptosis GADD45GIP1 GADD45G interacting protein 1 8.51 9.37 0.14 0.0 0.0 50.32 Detail
171 BRCA cuproptosis LONP1 lon peptidase 1, mitochondrial 10.07 10.68 0.09 0.0 0.0 50.16 Detail
172 BRCA cuproptosis MTFR1 mitochondrial fission regulator 1 8.69 9.4 0.11 0.0 0.0 50.01 Detail
173 BRCA cuproptosis CYCS cytochrome c, somatic 10.65 11.15 0.07 0.0 0.0 49.68 Detail
174 BRCA cuproptosis DYNLRB1 dynein light chain roadblock-type 1 10.59 11.1 0.07 0.0 0.0 49.65 Detail
175 BRCA cuproptosis SLC30A7 solute carrier family 30 member 7 9.45 9.9 0.07 0.0 0.0 49.52 Detail
176 BRCA cuproptosis HMBS hydroxymethylbilane synthase 7.99 8.54 0.1 0.0 0.0 49.12 Detail
177 BRCA cuproptosis BRCA1 BRCA1 DNA repair associated 7.65 8.4 0.13 0.0 0.0 49.05 Detail
178 BRCA cuproptosis PURG purine rich element binding protein G 3.09 2.23 -0.47 0.0 0.0 47.88 Detail
179 BRCA cuproptosis CEPT1 choline/ethanolamine phosphotransferase 1 9.81 9.39 -0.06 0.0 0.0 47.82 Detail
180 BRCA cuproptosis ATL2 atlastin GTPase 2 10.67 10.07 -0.08 0.0 0.0 47.47 Detail
181 BRCA cuproptosis GTPBP4 GTP binding protein 4 9.9 10.4 0.07 0.0 0.0 47.45 Detail
182 BRCA cuproptosis MCAT malonyl-CoA-acyl carrier protein transacylase 7.93 8.41 0.09 0.0 0.0 47.16 Detail
183 BRCA cuproptosis MT1A metallothionein 1A 4.84 3.09 -0.65 0.0 0.0 47.03 Detail
184 BRCA cuproptosis NDUFA8 NADH:ubiquinone oxidoreductase subunit A8 9.33 9.76 0.07 0.0 0.0 46.9 Detail
185 BRCA cuproptosis MTF1 metal regulatory transcription factor 1 9.56 9.12 -0.07 0.0 0.0 46.47 Detail
186 BRCA cuproptosis CDK5RAP1 CDK5 regulatory subunit associated protein 1 8.74 9.08 0.06 0.0 0.0 46.26 Detail
187 BRCA cuproptosis ABCB7 ATP binding cassette subfamily B member 7 9.11 8.76 -0.06 0.0 0.0 46.26 Detail
188 BRCA cuproptosis MRPS7 mitochondrial ribosomal protein S7 9.83 10.28 0.06 0.0 0.0 46.19 Detail
189 BRCA cuproptosis MFN2 mitofusin 2 11.55 11.19 -0.05 0.0 0.0 45.64 Detail
190 BRCA cuproptosis RPUSD3 RNA pseudouridine synthase D3 8.42 8.85 0.07 0.0 0.0 45.5 Detail
191 BRCA cuproptosis UQCRC2 ubiquinol-cytochrome c reductase core protein 2 12.07 11.67 -0.05 0.0 0.0 45.4 Detail
192 BRCA cuproptosis KLF5 KLF transcription factor 5 9.69 8.34 -0.22 0.0 0.0 45.18 Detail
193 BRCA cuproptosis RPS27A ribosomal protein S27a 13.5 12.97 -0.06 0.0 0.0 45.13 Detail
194 BRCA cuproptosis NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic 8.52 8.91 0.06 0.0 0.0 45.06 Detail
195 BRCA cuproptosis SP1 Sp1 transcription factor 11.93 11.59 -0.04 0.0 0.0 44.48 Detail
196 BRCA cuproptosis MRPS30 mitochondrial ribosomal protein S30 8.79 9.82 0.16 0.0 0.0 44.47 Detail
197 BRCA cuproptosis MRPL53 mitochondrial ribosomal protein L53 8.42 8.97 0.09 0.0 0.0 44.28 Detail
198 BRCA cuproptosis VPS45 vacuolar protein sorting 45 homolog 9.81 10.17 0.05 0.0 0.0 44.07 Detail
199 BRCA cuproptosis IMP4 IMP U3 small nucleolar ribonucleoprotein 4 8.92 9.32 0.06 0.0 0.0 44.04 Detail
200 BRCA cuproptosis PARS2 prolyl-tRNA synthetase 2, mitochondrial 6.87 7.3 0.09 0.0 0.0 43.74 Detail
201 BRCA cuproptosis NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 9.99 10.35 0.05 0.0 0.0 43.64 Detail
202 BRCA cuproptosis MRPL41 mitochondrial ribosomal protein L41 8.38 9.1 0.12 0.0 0.0 43.49 Detail
203 BRCA cuproptosis CYP1A1 cytochrome P450 family 1 subfamily A member 1 3.02 1.05 -1.53 0.0 0.0 43.47 Detail
204 BRCA cuproptosis SYMPK symplekin scaffold protein 10.51 10.92 0.06 0.0 0.0 43.41 Detail
205 BRCA cuproptosis MBTPS1 membrane bound transcription factor peptidase, site 1 11.96 11.65 -0.04 0.0 0.0 43.29 Detail
206 BRCA cuproptosis NLRP3 NLR family pyrin domain containing 3 6.9 5.98 -0.21 0.0 0.0 42.93 Detail
207 BRCA cuproptosis GCLM glutamate-cysteine ligase modifier subunit 8.9 8.4 -0.08 0.0 0.0 41.66 Detail
208 BRCA cuproptosis XRN1 5'-3' exoribonuclease 1 10.27 9.82 -0.07 0.0 0.0 41.63 Detail
209 BRCA cuproptosis NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 9.05 9.41 0.06 0.0 0.0 41.59 Detail
210 BRCA cuproptosis WDR12 WD repeat domain 12 8.44 8.81 0.06 0.0 0.0 41.55 Detail
211 BRCA cuproptosis UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 8.56 8.12 -0.08 0.0 0.0 41.45 Detail
212 BRCA cuproptosis AQP2 aquaporin 2 1.57 0.81 -0.95 0.0 0.0 41.34 Detail
213 BRCA cuproptosis ACLY ATP citrate lyase 11.64 12.05 0.05 0.0 0.0 41.12 Detail
214 BRCA cuproptosis STEAP2 STEAP2 metalloreductase 9.82 8.74 -0.17 0.0 0.0 40.98 Detail
215 BRCA cuproptosis HSPA9 heat shock protein family A (Hsp70) member 9 12.36 12.7 0.04 0.0 0.0 40.9 Detail
216 BRCA cuproptosis DOT1L DOT1 like histone lysine methyltransferase 8.72 9.2 0.08 0.0 0.0 40.8 Detail
217 BRCA cuproptosis FDX1 ferredoxin 1 8.74 8.31 -0.07 0.0 0.0 40.78 Detail
218 BRCA cuproptosis HSPD1 heat shock protein family D (Hsp60) member 1 12.39 12.86 0.05 0.0 0.0 40.23 Detail
219 BRCA cuproptosis MCM5 minichromosome maintenance complex component 5 9.34 9.93 0.09 0.0 0.0 40.2 Detail
220 BRCA cuproptosis SERPIND1 serpin family D member 1 2.16 0.92 -1.24 0.0 0.0 39.58 Detail
221 BRCA cuproptosis SLC16A6 solute carrier family 16 member 6 5.82 7.39 0.34 0.0 0.0 39.31 Detail
222 BRCA cuproptosis MRPS11 mitochondrial ribosomal protein S11 8.74 9.11 0.06 0.0 0.0 39.17 Detail
223 BRCA cuproptosis MRPL21 mitochondrial ribosomal protein L21 8.6 9.11 0.08 0.0 0.0 38.96 Detail
224 BRCA cuproptosis UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 9.86 10.32 0.07 0.0 0.0 38.77 Detail
225 BRCA cuproptosis MAP2K2 mitogen-activated protein kinase kinase 2 10.31 10.75 0.06 0.0 0.0 38.67 Detail
226 BRCA cuproptosis IDH1 isocitrate dehydrogenase (NADP(+)) 1 11.62 11.05 -0.07 0.0 0.0 38.61 Detail
227 BRCA cuproptosis COQ2 coenzyme Q2, polyprenyltransferase 7.28 7.66 0.07 0.0 0.0 38.59 Detail
228 BRCA cuproptosis CCL20 C-C motif chemokine ligand 20 1.66 2.99 0.85 0.0 0.0 38.59 Detail
229 BRCA cuproptosis DBT dihydrolipoamide branched chain transacylase E2 9.85 9.45 -0.06 0.0 0.0 38.54 Detail
230 BRCA cuproptosis SAMM50 SAMM50 sorting and assembly machinery component 10.25 9.9 -0.05 0.0 0.0 38.35 Detail
231 BRCA cuproptosis GLRX5 glutaredoxin 5 9.54 9.86 0.05 0.0 0.0 38.26 Detail
232 BRCA cuproptosis COX6B1 cytochrome c oxidase subunit 6B1 11.07 11.52 0.06 0.0 0.0 38.25 Detail
233 BRCA cuproptosis GLS glutaminase 10.6 10.11 -0.07 0.0 0.0 38.12 Detail
234 BRCA cuproptosis NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 10.4 10.77 0.05 0.0 0.0 37.92 Detail
235 BRCA cuproptosis SLC25A3 solute carrier family 25 member 3 12.82 12.54 -0.03 0.0 0.0 37.34 Detail
236 BRCA cuproptosis UQCRC1 ubiquinol-cytochrome c reductase core protein 1 11.08 11.42 0.04 0.0 0.0 37.01 Detail
237 BRCA cuproptosis GCLC glutamate-cysteine ligase catalytic subunit 10.08 9.61 -0.07 0.0 0.0 36.72 Detail
238 BRCA cuproptosis HARS2 histidyl-tRNA synthetase 2, mitochondrial 9.47 9.71 0.04 0.0 0.0 36.51 Detail
239 BRCA cuproptosis NFS1 NFS1 cysteine desulfurase 8.91 9.24 0.05 0.0 0.0 36.39 Detail
240 BRCA cuproptosis CAPRIN1 cell cycle associated protein 1 12.61 12.94 0.04 0.0 0.0 36.37 Detail
241 BRCA cuproptosis CCS copper chaperone for superoxide dismutase 8.32 8.88 0.1 0.0 0.0 36.34 Detail
242 BRCA cuproptosis NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 10.0 10.45 0.06 0.0 0.0 35.57 Detail
243 BRCA cuproptosis MT1E metallothionein 1E 9.64 8.57 -0.17 0.0 0.0 35.38 Detail
244 BRCA cuproptosis MTIF3 mitochondrial translational initiation factor 3 9.81 9.46 -0.05 0.0 0.0 35.38 Detail
245 BRCA cuproptosis C1QBP complement C1q binding protein 10.27 10.67 0.06 0.0 0.0 35.36 Detail
246 BRCA cuproptosis HEPH hephaestin 9.36 8.7 -0.11 0.0 0.0 35.26 Detail
247 BRCA cuproptosis RPL28 ribosomal protein L28 12.83 13.42 0.06 0.0 0.0 35.19 Detail
248 BRCA cuproptosis NFU1 NFU1 iron-sulfur cluster scaffold 9.43 9.02 -0.06 0.0 0.0 35.0 Detail
249 BRCA cuproptosis CISD1 CDGSH iron sulfur domain 1 8.08 8.37 0.05 0.0 0.0 34.89 Detail
250 BRCA cuproptosis NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 10.72 11.22 0.07 0.0 0.0 34.84 Detail
251 BRCA cuproptosis SDHAF2 succinate dehydrogenase complex assembly factor 2 9.17 9.43 0.04 0.0 0.0 34.73 Detail
252 BRCA cuproptosis RAD9A RAD9 checkpoint clamp component A 7.6 8.11 0.09 0.0 0.0 34.44 Detail
253 BRCA cuproptosis ATP8B1 ATPase phospholipid transporting 8B1 10.11 10.69 0.08 0.0 0.0 34.32 Detail
254 BRCA cuproptosis RTEL1 regulator of telomere elongation helicase 1 8.14 8.63 0.08 0.0 0.0 33.37 Detail
255 BRCA cuproptosis MTG1 mitochondrial ribosome associated GTPase 1 8.41 8.83 0.07 0.0 0.0 33.13 Detail
256 BRCA cuproptosis EGLN1 egl-9 family hypoxia inducible factor 1 10.57 10.19 -0.05 0.0 0.0 33.09 Detail
257 BRCA cuproptosis MOXD1 monooxygenase DBH like 1 6.58 7.37 0.16 0.0 0.0 32.96 Detail
258 BRCA cuproptosis STK11 serine/threonine kinase 11 9.48 9.86 0.06 0.0 0.0 32.82 Detail
259 BRCA cuproptosis CCL8 C-C motif chemokine ligand 8 6.69 5.47 -0.29 0.0 0.0 32.64 Detail
260 BRCA cuproptosis TOP1MT DNA topoisomerase I mitochondrial 8.54 9.22 0.11 0.0 0.0 32.4 Detail
261 BRCA cuproptosis HSPA8 heat shock protein family A (Hsp70) member 8 14.24 14.53 0.03 0.0 0.0 32.37 Detail
262 BRCA cuproptosis MECR mitochondrial trans-2-enoyl-CoA reductase 8.82 8.48 -0.06 0.0 0.0 32.07 Detail
263 BRCA cuproptosis ELP3 elongator acetyltransferase complex subunit 3 9.72 9.41 -0.05 0.0 0.0 31.01 Detail
264 BRCA cuproptosis NDUFA9 NADH:ubiquinone oxidoreductase subunit A9 10.06 10.36 0.04 0.0 0.0 30.68 Detail
265 BRCA cuproptosis SOD1 superoxide dismutase 1 11.64 12.01 0.04 0.0 0.0 30.63 Detail
266 BRCA cuproptosis ULK1 unc-51 like autophagy activating kinase 1 10.05 10.37 0.05 0.0 0.0 30.57 Detail
267 BRCA cuproptosis PRKDC protein kinase, DNA-activated, catalytic subunit 12.03 12.49 0.05 0.0 0.0 30.53 Detail
268 BRCA cuproptosis MRPS18A mitochondrial ribosomal protein S18A 9.13 9.43 0.05 0.0 0.0 30.36 Detail
269 BRCA cuproptosis APP amyloid beta precursor protein 14.75 14.32 -0.04 0.0 0.0 29.99 Detail
270 BRCA cuproptosis LARS2 leucyl-tRNA synthetase 2, mitochondrial 8.79 9.04 0.04 0.0 0.0 29.86 Detail
271 BRCA cuproptosis TSC22D2 TSC22 domain family member 2 9.39 9.01 -0.06 0.0 0.0 29.71 Detail
272 BRCA cuproptosis ULK2 unc-51 like autophagy activating kinase 2 9.73 9.34 -0.06 0.0 0.0 29.56 Detail
273 BRCA cuproptosis COX15 cytochrome c oxidase assembly homolog COX15 10.2 9.98 -0.03 0.0 0.0 29.45 Detail
274 BRCA cuproptosis ISCA2 iron-sulfur cluster assembly 2 8.03 8.29 0.05 0.0 0.0 29.07 Detail
275 BRCA cuproptosis UBA2 ubiquitin like modifier activating enzyme 2 11.42 11.12 -0.04 0.0 0.0 28.89 Detail
276 BRCA cuproptosis RPL3 ribosomal protein L3 15.35 14.93 -0.04 0.0 0.0 28.75 Detail
277 BRCA cuproptosis DBR1 debranching RNA lariats 1 8.51 8.7 0.03 0.0 0.0 28.58 Detail
278 BRCA cuproptosis DLD dihydrolipoamide dehydrogenase 11.05 10.7 -0.05 0.0 0.0 28.45 Detail
279 BRCA cuproptosis ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 7.86 8.18 0.06 0.0 0.0 28.45 Detail
280 BRCA cuproptosis PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 10.66 10.34 -0.04 0.0 0.0 28.41 Detail
281 BRCA cuproptosis FGD6 FYVE, RhoGEF and PH domain containing 6 8.79 9.29 0.08 0.0 0.0 28.32 Detail
282 BRCA cuproptosis RPL10A ribosomal protein L10a 13.68 13.31 -0.04 0.0 0.0 27.62 Detail
283 BRCA cuproptosis CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X 9.68 9.42 -0.04 0.0 0.0 27.6 Detail
284 BRCA cuproptosis MRPL34 mitochondrial ribosomal protein L34 8.83 9.18 0.06 0.0 0.0 27.34 Detail
285 BRCA cuproptosis NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 10.18 10.51 0.05 0.0 0.0 27.3 Detail
286 BRCA cuproptosis HAUS5 HAUS augmin like complex subunit 5 8.04 8.46 0.07 0.0 0.0 26.92 Detail
287 BRCA cuproptosis MRPL44 mitochondrial ribosomal protein L44 9.12 9.29 0.03 0.0 0.0 26.83 Detail
288 BRCA cuproptosis BCL2 BCL2 apoptosis regulator 11.09 10.18 -0.12 0.0 0.0 26.28 Detail
289 BRCA cuproptosis SERPINE1 serpin family E member 1 9.09 10.04 0.14 0.0 0.0 26.19 Detail
290 BRCA cuproptosis CP ceruloplasmin 9.57 7.87 -0.28 0.0 0.0 25.8 Detail
291 BRCA cuproptosis VEGFA vascular endothelial growth factor A 10.38 10.86 0.06 0.0 0.0 25.51 Detail
292 BRCA cuproptosis ATP7A ATPase copper transporting alpha 9.46 9.03 -0.07 0.0 0.0 25.45 Detail
293 BRCA cuproptosis ZBP1 Z-DNA binding protein 1 4.05 5.06 0.32 0.0 0.0 25.38 Detail
294 BRCA cuproptosis TAF6L TATA-box binding protein associated factor 6 like 7.6 7.91 0.06 0.0 0.0 24.72 Detail
295 BRCA cuproptosis CDC16 cell division cycle 16 10.66 10.45 -0.03 0.0 0.0 24.44 Detail
296 BRCA cuproptosis FZD8 frizzled class receptor 8 8.61 8.06 -0.1 0.0 0.0 24.2 Detail
297 BRCA cuproptosis NDUFC1 NADH:ubiquinone oxidoreductase subunit C1 9.18 9.44 0.04 0.0 0.0 24.0 Detail
298 BRCA cuproptosis PCBP2 poly(rC) binding protein 2 13.44 13.27 -0.02 0.0 0.0 23.62 Detail
299 BRCA cuproptosis RIPK1 receptor interacting serine/threonine kinase 1 10.19 10.02 -0.02 0.0 0.0 23.56 Detail
300 BRCA cuproptosis PCGF6 polycomb group ring finger 6 7.66 7.42 -0.05 0.0 0.0 23.46 Detail
301 BRCA cuproptosis HCCS holocytochrome c synthase 8.63 8.86 0.04 0.0 0.0 23.43 Detail
302 BRCA cuproptosis GNL3 G protein nucleolar 3 10.57 10.85 0.04 0.0 0.0 23.39 Detail
303 BRCA cuproptosis MRPS33 mitochondrial ribosomal protein S33 9.1 9.36 0.04 0.0 0.0 23.23 Detail
304 BRCA cuproptosis FXN frataxin 7.86 7.65 -0.04 0.0 0.0 23.06 Detail
305 BRCA cuproptosis CS citrate synthase 12.29 11.92 -0.04 0.0 0.0 22.32 Detail
306 BRCA cuproptosis RRN3 RRN3 homolog, RNA polymerase I transcription factor 10.43 10.66 0.03 0.0 0.0 22.32 Detail
307 BRCA cuproptosis SNAPIN SNAP associated protein 9.29 9.53 0.04 0.0 0.0 22.31 Detail
308 BRCA cuproptosis NDUFA4 NDUFA4 mitochondrial complex associated 11.27 11.53 0.03 0.0 0.0 22.02 Detail
309 BRCA cuproptosis ACTR10 actin related protein 10 10.16 9.98 -0.03 0.0 0.0 22.01 Detail
310 BRCA cuproptosis PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.46 10.68 0.03 0.0 0.0 21.99 Detail
311 BRCA cuproptosis MT1H metallothionein 1H 0.59 1.39 1.22 0.0 0.0 21.98 Detail
312 BRCA cuproptosis PARK7 Parkinsonism associated deglycase 11.66 11.9 0.03 0.0 0.0 21.69 Detail
313 BRCA cuproptosis PLOD1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 11.31 11.68 0.05 0.0 0.0 21.45 Detail
314 BRCA cuproptosis NUP133 nucleoporin 133 10.51 10.73 0.03 0.0 0.0 21.28 Detail
315 BRCA cuproptosis ELF3 E74 like ETS transcription factor 3 10.56 11.86 0.17 0.0 0.0 21.21 Detail
316 BRCA cuproptosis FPGS folylpolyglutamate synthase 9.57 9.84 0.04 0.0 0.0 20.76 Detail
317 BRCA cuproptosis ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 6.7 5.95 -0.17 0.0 0.0 20.71 Detail
318 BRCA cuproptosis DHX15 DEAH-box helicase 15 11.31 11.5 0.02 0.0 0.0 20.3 Detail
319 BRCA cuproptosis RB1 RB transcriptional corepressor 1 10.39 9.98 -0.06 0.0 0.0 20.15 Detail
320 BRCA cuproptosis NDUFA6 NADH:ubiquinone oxidoreductase subunit A6 9.71 9.97 0.04 0.0 0.0 20.06 Detail
321 BRCA cuproptosis COX7B cytochrome c oxidase subunit 7B 10.25 10.52 0.04 0.0 0.0 20.04 Detail
322 BRCA cuproptosis PRDM10 PR/SET domain 10 8.2 7.96 -0.04 0.0 0.0 19.98 Detail
323 BRCA cuproptosis ABCB10 ATP binding cassette subfamily B member 10 8.78 9.04 0.04 0.0 0.0 19.95 Detail
324 BRCA cuproptosis OXA1L OXA1L mitochondrial inner membrane protein 11.17 10.98 -0.02 0.0 0.0 19.64 Detail
325 BRCA cuproptosis FAM111A FAM111 trypsin like peptidase A 9.66 9.92 0.04 0.0 0.0 19.48 Detail
326 BRCA cuproptosis ATP7B ATPase copper transporting beta 8.01 8.51 0.09 0.0 0.0 19.34 Detail
327 BRCA cuproptosis GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 11.02 11.15 0.02 0.0 0.0 19.26 Detail
328 BRCA cuproptosis TADA2A transcriptional adaptor 2A 7.63 7.42 -0.04 0.0 0.0 19.24 Detail
329 BRCA cuproptosis IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma 9.62 9.87 0.04 0.0 0.0 18.79 Detail
330 BRCA cuproptosis NDUFB7 NADH:ubiquinone oxidoreductase subunit B7 9.61 9.98 0.05 0.0 0.0 18.34 Detail
331 BRCA cuproptosis MPZL3 myelin protein zero like 3 5.45 5.09 -0.1 0.0 0.0 17.51 Detail
332 BRCA cuproptosis GCSH glycine cleavage system protein H 4.64 4.12 -0.17 0.0 0.0 17.05 Detail
333 BRCA cuproptosis EXOC3 exocyst complex component 3 10.29 10.14 -0.02 0.0 0.0 16.98 Detail
334 BRCA cuproptosis GFM1 G elongation factor mitochondrial 1 10.32 10.5 0.02 0.0 0.0 16.86 Detail
335 BRCA cuproptosis MT3 metallothionein 3 0.43 1.12 1.39 0.0 0.0 16.27 Detail
336 BRCA cuproptosis WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 8.74 8.55 -0.03 0.0 0.0 16.18 Detail
337 BRCA cuproptosis SURF6 surfeit 6 9.09 9.36 0.04 0.0 0.0 15.9 Detail
338 BRCA cuproptosis MTO1 mitochondrial tRNA translation optimization 1 8.76 8.59 -0.03 0.0 0.0 15.51 Detail
339 BRCA cuproptosis ATF4 activating transcription factor 4 12.6 12.39 -0.02 0.0 0.0 15.44 Detail
340 BRCA cuproptosis GTF2B general transcription factor IIB 9.21 9.06 -0.02 0.0 0.0 14.91 Detail
341 BRCA cuproptosis GATC glutamyl-tRNA amidotransferase subunit C 4.74 5.01 0.08 0.0 0.0 14.89 Detail
342 BRCA cuproptosis STEAP3 STEAP3 metalloreductase 10.28 9.91 -0.05 0.0 0.0 14.56 Detail
343 BRCA cuproptosis CIAPIN1 cytokine induced apoptosis inhibitor 1 9.39 9.63 0.04 0.0 0.0 14.54 Detail
344 BRCA cuproptosis COX7C cytochrome c oxidase subunit 7C 11.34 11.53 0.02 0.0 0.0 14.41 Detail
345 BRCA cuproptosis SLC16A1 solute carrier family 16 member 1 9.45 9.11 -0.05 0.0 0.0 14.3 Detail
346 BRCA cuproptosis MAP2K1 mitogen-activated protein kinase kinase 1 10.25 9.98 -0.04 0.0 0.0 14.13 Detail
347 BRCA cuproptosis MRPS2 mitochondrial ribosomal protein S2 9.49 9.7 0.03 0.0 0.0 14.12 Detail
348 BRCA cuproptosis IFT81 intraflagellar transport 81 8.12 8.37 0.04 0.0 0.0 13.69 Detail
349 BRCA cuproptosis DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 10.56 10.44 -0.02 0.0 0.0 13.6 Detail
350 BRCA cuproptosis TUBGCP4 tubulin gamma complex component 4 8.29 8.07 -0.04 0.0 0.0 13.49 Detail
351 BRCA cuproptosis PTPMT1 protein tyrosine phosphatase mitochondrial 1 9.47 9.65 0.03 0.0 0.0 13.35 Detail
352 BRCA cuproptosis EIF3I eukaryotic translation initiation factor 3 subunit I 11.71 11.87 0.02 0.0 0.0 13.07 Detail
353 BRCA cuproptosis SLC31A1 solute carrier family 31 member 1 10.24 10.45 0.03 0.0 0.0 13.02 Detail
354 BRCA cuproptosis PSMD6 proteasome 26S subunit, non-ATPase 6 10.03 10.16 0.02 0.0 0.0 12.83 Detail
355 BRCA cuproptosis PPA2 inorganic pyrophosphatase 2 9.92 10.06 0.02 0.0 0.0 12.8 Detail
356 BRCA cuproptosis ZNF365 zinc finger protein 365 5.43 5.9 0.12 0.0 0.0 12.76 Detail
357 BRCA cuproptosis MRPS25 mitochondrial ribosomal protein S25 9.57 9.44 -0.02 0.0 0.0 12.63 Detail
358 BRCA cuproptosis PHF5A PHD finger protein 5A 8.68 8.87 0.03 0.0 0.0 12.56 Detail
359 BRCA cuproptosis RPL27 ribosomal protein L27 13.14 12.89 -0.03 0.0 0.0 12.25 Detail
360 BRCA cuproptosis LDLR low density lipoprotein receptor 10.41 9.97 -0.06 0.0 0.0 12.19 Detail
361 BRCA cuproptosis UBE2D3 ubiquitin conjugating enzyme E2 D3 12.42 12.29 -0.01 0.0 0.0 12.02 Detail
362 BRCA cuproptosis PDK1 pyruvate dehydrogenase kinase 1 8.73 8.46 -0.04 0.0 0.0 11.94 Detail
363 BRCA cuproptosis MARS2 methionyl-tRNA synthetase 2, mitochondrial 7.44 7.72 0.05 0.0 0.0 11.79 Detail
364 BRCA cuproptosis CDC27 cell division cycle 27 10.67 10.51 -0.02 0.0 0.0 11.51 Detail
365 BRCA cuproptosis SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit 11.62 11.75 0.02 0.0 0.0 11.4 Detail
366 BRCA cuproptosis TKT transketolase 12.15 11.87 -0.03 0.0 0.0 11.33 Detail
367 BRCA cuproptosis COX4I1 cytochrome c oxidase subunit 4I1 12.01 11.82 -0.02 0.0 0.0 11.24 Detail
368 BRCA cuproptosis REXO2 RNA exonuclease 2 9.52 9.34 -0.03 0.0 0.0 11.14 Detail
369 BRCA cuproptosis SPATA13 spermatogenesis associated 13 8.89 8.46 -0.07 0.0 0.0 10.63 Detail
370 BRCA cuproptosis NRF1 nuclear respiratory factor 1 8.75 8.66 -0.02 0.0 0.0 10.55 Detail
371 BRCA cuproptosis POT1 protection of telomeres 1 9.09 9.26 0.03 0.0 0.0 10.3 Detail
372 BRCA cuproptosis RPL7A ribosomal protein L7a 14.0 13.8 -0.02 0.0 0.0 10.0 Detail
373 BRCA cuproptosis ANKRD9 ankyrin repeat domain 9 5.74 6.03 0.07 0.0 0.0 9.92 Detail
374 BRCA cuproptosis IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha 10.0 9.83 -0.02 0.0 0.0 9.9 Detail
375 BRCA cuproptosis HIST1H3A H3 clustered histone 1 0.37 0.65 0.81 0.0 0.0 9.67 Detail
376 BRCA cuproptosis MLKL mixed lineage kinase domain like pseudokinase 7.7 7.44 -0.05 0.0 0.0 9.57 Detail
377 BRCA cuproptosis SARS2 seryl-tRNA synthetase 2, mitochondrial 8.04 8.25 0.04 0.0 0.0 9.46 Detail
378 BRCA cuproptosis ABCB4 ATP binding cassette subfamily B member 4 4.45 4.69 0.08 0.0 0.0 9.2 Detail
379 BRCA cuproptosis MFF mitochondrial fission factor 10.17 10.1 -0.01 0.0 0.0 9.14 Detail
380 BRCA cuproptosis STARD7 StAR related lipid transfer domain containing 7 11.7 11.82 0.01 0.0 0.01 8.47 Detail
381 BRCA cuproptosis LOXL2 lysyl oxidase like 2 9.92 10.23 0.04 0.01 0.01 8.27 Detail
382 BRCA cuproptosis COQ7 coenzyme Q7, hydroxylase 8.91 9.05 0.02 0.01 0.01 8.15 Detail
383 BRCA cuproptosis NFKBIA NFKB inhibitor alpha 11.4 11.13 -0.03 0.01 0.01 8.07 Detail
384 BRCA cuproptosis MRPS18B mitochondrial ribosomal protein S18B 10.38 10.51 0.02 0.01 0.01 8.03 Detail
385 BRCA cuproptosis DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 9.86 9.97 0.02 0.01 0.01 7.97 Detail
386 BRCA cuproptosis RAD23B RAD23 homolog B, nucleotide excision repair protein 12.13 12.24 0.01 0.01 0.01 7.96 Detail
387 BRCA cuproptosis NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 10.57 10.36 -0.03 0.01 0.01 7.89 Detail
388 BRCA cuproptosis AFG3L2 AFG3 like matrix AAA peptidase subunit 2 10.38 10.5 0.02 0.01 0.01 7.76 Detail
389 BRCA cuproptosis DLAT dihydrolipoamide S-acetyltransferase 9.93 9.76 -0.03 0.01 0.01 7.43 Detail
390 BRCA cuproptosis TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 8.99 9.15 0.03 0.01 0.01 6.94 Detail
391 BRCA cuproptosis FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 7.89 7.98 0.02 0.01 0.01 6.9 Detail
392 BRCA cuproptosis NARS2 asparaginyl-tRNA synthetase 2, mitochondrial 8.45 8.65 0.03 0.01 0.01 6.87 Detail
393 BRCA cuproptosis SURF1 SURF1 cytochrome c oxidase assembly factor 9.4 9.54 0.02 0.01 0.01 6.57 Detail
394 BRCA cuproptosis SOX2 SRY-box transcription factor 2 1.43 2.54 0.82 0.01 0.01 6.46 Detail
395 BRCA cuproptosis SLC25A32 solute carrier family 25 member 32 9.05 9.24 0.03 0.01 0.01 6.45 Detail
396 BRCA cuproptosis UBE2D1 ubiquitin conjugating enzyme E2 D1 8.52 8.65 0.02 0.01 0.01 6.44 Detail
397 BRCA cuproptosis CD274 CD274 molecule 4.73 4.43 -0.09 0.01 0.01 6.33 Detail
398 BRCA cuproptosis GPX4 glutathione peroxidase 4 11.97 11.7 -0.03 0.01 0.01 6.25 Detail
399 BRCA cuproptosis TIMM9 translocase of inner mitochondrial membrane 9 9.1 8.97 -0.02 0.01 0.01 6.05 Detail
400 BRCA cuproptosis MRPS5 mitochondrial ribosomal protein S5 9.29 9.47 0.03 0.01 0.02 5.82 Detail
401 BRCA cuproptosis PTCD3 pentatricopeptide repeat domain 3 10.06 9.96 -0.01 0.01 0.02 5.37 Detail
402 BRCA cuproptosis RPAP1 RNA polymerase II associated protein 1 9.24 9.13 -0.02 0.01 0.02 5.22 Detail
403 BRCA cuproptosis PDHX pyruvate dehydrogenase complex component X 9.49 9.59 0.02 0.02 0.02 4.9 Detail
404 BRCA cuproptosis SPATA5 AFG2 AAA ATPase homolog A 7.95 7.81 -0.03 0.02 0.02 4.5 Detail
405 BRCA cuproptosis LOX lysyl oxidase 9.91 9.52 -0.06 0.02 0.02 4.44 Detail
406 BRCA cuproptosis POLG DNA polymerase gamma, catalytic subunit 9.97 9.88 -0.01 0.02 0.02 4.4 Detail
407 BRCA cuproptosis CIAO1 cytosolic iron-sulfur assembly component 1 10.81 10.88 0.01 0.02 0.03 4.25 Detail
408 BRCA cuproptosis RSL1D1 ribosomal L1 domain containing 1 12.21 12.1 -0.01 0.02 0.03 3.9 Detail
409 BRCA cuproptosis PDHB pyruvate dehydrogenase E1 subunit beta 10.23 10.32 0.01 0.02 0.03 3.73 Detail
410 BRCA cuproptosis ANKRD49 ankyrin repeat domain 49 8.16 8.04 -0.02 0.03 0.03 3.32 Detail
411 BRCA cuproptosis SCO1 synthesis of cytochrome C oxidase 1 8.83 8.73 -0.02 0.04 0.04 2.44 Detail
412 BRCA cuproptosis C7orf26 integrator complex subunit 15 9.01 9.1 0.02 0.04 0.05 2.23 Detail
413 BRCA cuproptosis MUC20 mucin 20, cell surface associated 7.53 7.25 -0.06 0.04 0.05 2.09 Detail
414 BRCA cuproptosis ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) 8.91 8.92 0.0 0.66 0.69 0.0 Detail
415 BRCA cuproptosis COX19 cytochrome c oxidase assembly factor COX19 7.94 7.91 -0.0 0.66 0.7 0.0 Detail
416 BRCA cuproptosis MT2A metallothionein 2A 11.13 10.91 -0.03 0.08 0.1 0.0 Detail
417 BRCA cuproptosis PRND prion like protein doppel 5.65 5.33 -0.09 0.18 0.2 0.0 Detail
418 BRCA cuproptosis AOC1 amine oxidase copper containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
419 BRCA cuproptosis BECN1 beclin 1 10.74 10.77 0.0 0.29 0.32 0.0 Detail
420 BRCA cuproptosis MAP1LC3A microtubule associated protein 1 light chain 3 alpha 8.14 8.12 -0.0 0.85 0.86 0.0 Detail
421 BRCA cuproptosis MT1B metallothionein 1B 0.0 0.02 inf 0.19 0.21 0.0 Detail
422 BRCA cuproptosis MT1DP metallothionein 1D, pseudogene 1.46 1.39 -0.08 0.09 0.11 0.0 Detail
423 BRCA cuproptosis MT1F metallothionein 1F 6.63 6.61 -0.0 0.36 0.39 0.0 Detail
424 BRCA cuproptosis MT1G metallothionein 1G 6.04 5.97 -0.02 0.39 0.42 0.0 Detail
425 BRCA cuproptosis MT1HL1 metallothionein 1H like 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
426 BRCA cuproptosis MT4 metallothionein 4 0.0 0.02 inf 0.17 0.2 0.0 Detail
427 BRCA cuproptosis COMMD1 copper metabolism domain containing 1 8.13 8.17 0.01 0.7 0.73 0.0 Detail
428 BRCA cuproptosis XIAP X-linked inhibitor of apoptosis 10.62 10.57 -0.01 0.62 0.66 0.0 Detail
429 BRCA cuproptosis SLC11A2 solute carrier family 11 member 2 10.57 10.62 0.01 0.87 0.89 0.0 Detail
430 BRCA cuproptosis HEPHL1 hephaestin like 1 1.51 1.68 0.16 0.53 0.57 0.0 Detail
431 BRCA cuproptosis FASLG Fas ligand 3.67 3.8 0.05 0.54 0.58 0.0 Detail
432 BRCA cuproptosis RIPK3 receptor interacting serine/threonine kinase 3 7.26 7.09 -0.04 0.84 0.86 0.0 Detail
433 BRCA cuproptosis TNF tumor necrosis factor 4.95 4.9 -0.01 0.74 0.76 0.0 Detail
434 BRCA cuproptosis AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 9.69 9.68 -0.0 0.8 0.82 0.0 Detail
435 BRCA cuproptosis ABCE1 ATP binding cassette subfamily E member 1 10.6 10.66 0.01 0.34 0.38 0.0 Detail
436 BRCA cuproptosis ACD ACD shelterin complex subunit and telomerase recruitment factor 8.26 8.31 0.01 0.6 0.64 0.0 Detail
437 BRCA cuproptosis ACO2 aconitase 2 11.41 11.3 -0.01 0.25 0.28 0.0 Detail
438 BRCA cuproptosis ADGRE5 adhesion G protein-coupled receptor E5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
439 BRCA cuproptosis ALAS1 5'-aminolevulinate synthase 1 9.95 9.9 -0.01 0.5 0.54 0.0 Detail
440 BRCA cuproptosis API5 apoptosis inhibitor 5 11.33 11.33 -0.0 0.88 0.89 0.0 Detail
441 BRCA cuproptosis ARFGEF1-DT ARFGEF1 divergent transcript 0.0 0.0 0.0 0.0 0.0 0.0 Detail
442 BRCA cuproptosis ARHGEF39 Rho guanine nucleotide exchange factor 39 0.0 0.0 0.0 0.0 0.0 0.0 Detail
443 BRCA cuproptosis ARMH3 armadillo like helical domain containing 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
444 BRCA cuproptosis ATP5PD ATP synthase peripheral stalk subunit d 0.0 0.0 0.0 0.0 0.0 0.0 Detail
445 BRCA cuproptosis ATP7BP1 ATPase copper transporting beta pseudogene 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
446 BRCA cuproptosis BARX1 BARX homeobox 1 2.04 2.48 0.28 0.12 0.15 0.0 Detail
447 BRCA cuproptosis BCKDH protein phosphatase, Mg2+/Mn2+ dependent 1K 0.0 0.0 0.0 0.0 0.0 0.0 Detail
448 BRCA cuproptosis BRPF1 bromodomain and PHD finger containing 1 9.16 9.2 0.01 0.71 0.74 0.0 Detail
449 BRCA cuproptosis C6ORF136 chromosome 6 open reading frame 136 0.0 0.0 0.0 0.0 0.0 0.0 Detail
450 BRCA cuproptosis CCDC115 coiled-coil domain containing 115 9.87 9.83 -0.01 0.42 0.46 0.0 Detail
451 BRCA cuproptosis CCL5 C-C motif chemokine ligand 5 8.77 9.02 0.04 0.12 0.14 0.0 Detail
452 BRCA cuproptosis CENPJ centromere protein J 7.68 7.55 -0.02 0.05 0.06 0.0 Detail
453 BRCA cuproptosis CERS2 ceramide synthase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
454 BRCA cuproptosis CERT1 ceramide transporter 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
455 BRCA cuproptosis CHTOP chromatin target of PRMT1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
456 BRCA cuproptosis CIAO2A cytosolic iron-sulfur assembly component 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
457 BRCA cuproptosis CIAO2B cytosolic iron-sulfur assembly component 2B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
458 BRCA cuproptosis CLUH clustered mitochondria homolog 0.0 0.0 0.0 0.0 0.0 0.0 Detail
459 BRCA cuproptosis COA5 cytochrome c oxidase assembly factor 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
460 BRCA cuproptosis COA6 cytochrome c oxidase assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
461 BRCA cuproptosis COAS unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
462 BRCA cuproptosis copper鈥搝inc alloy (CZA) unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
463 BRCA cuproptosis COX11 cytochrome c oxidase copper chaperone COX11 9.5 9.44 -0.01 0.08 0.1 0.0 Detail
464 BRCA cuproptosis COX14 cytochrome c oxidase assembly factor COX14 0.0 0.0 0.0 0.0 0.0 0.0 Detail
465 BRCA cuproptosis COX18 cytochrome c oxidase assembly factor COX18 8.56 8.62 0.01 0.33 0.36 0.0 Detail
466 BRCA cuproptosis COX23 coiled-coil-helix-coiled-coil-helix domain containing 7 0.0 0.0 0.0 0.0 0.0 0.0 Detail
467 BRCA cuproptosis CTR1 solute carrier family 31 member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
468 BRCA cuproptosis CTR2 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
469 BRCA cuproptosis CYP2D6 cytochrome P450 family 2 subfamily D member 6 2.85 3.02 0.08 0.67 0.71 0.0 Detail
470 BRCA cuproptosis DARS1 aspartyl-tRNA synthetase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
471 BRCA cuproptosis DBH dopamine beta-hydroxylase 1.8 1.98 0.13 0.15 0.17 0.0 Detail
472 BRCA cuproptosis DCYTB cytochrome b reductase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
473 BRCA cuproptosis DDX20 DEAD-box helicase 20 8.96 8.95 -0.0 0.71 0.74 0.0 Detail
474 BRCA cuproptosis DIP2B disco interacting protein 2 homolog B 10.51 10.57 0.01 0.29 0.32 0.0 Detail
475 BRCA cuproptosis DMT1 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
476 BRCA cuproptosis DNM1L dynamin 1 like 10.55 10.65 0.01 0.11 0.13 0.0 Detail
477 BRCA cuproptosis DPH1 diphthamide biosynthesis 1 9.23 9.13 -0.02 0.07 0.08 0.0 Detail
478 BRCA cuproptosis EFCC1 EF-hand and coiled-coil domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
479 BRCA cuproptosis ELOB elongin B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
480 BRCA cuproptosis EMC6 ER membrane protein complex subunit 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
481 BRCA cuproptosis ERK1 mitogen-activated protein kinase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
482 BRCA cuproptosis FAK protein tyrosine kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
483 BRCA cuproptosis FASTKD5 FAST kinase domains 5 8.73 8.79 0.01 0.19 0.22 0.0 Detail
484 BRCA cuproptosis FAU FAU ubiquitin like and ribosomal protein S30 fusion 12.34 12.38 0.0 0.75 0.77 0.0 Detail
485 BRCA cuproptosis FDX2 ferredoxin 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
486 BRCA cuproptosis FOXD2-AS1 FOXD2 adjacent opposite strand RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
487 BRCA cuproptosis GATB glutamyl-tRNA amidotransferase subunit B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
488 BRCA cuproptosis GLS40 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
489 BRCA cuproptosis glycerophospholipid unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
490 BRCA cuproptosis GRX1 glutaredoxin 0.0 0.0 0.0 0.0 0.0 0.0 Detail
491 BRCA cuproptosis GSH unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
492 BRCA cuproptosis GTPBP6 GTP binding protein 6 (putative) 0.0 0.0 0.0 0.0 0.0 0.0 Detail
493 BRCA cuproptosis H1-10-AS1 H1-10 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
494 BRCA cuproptosis H2AC6 H2A clustered histone 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
495 BRCA cuproptosis H2BC6-AS1 H2BC6 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
496 BRCA cuproptosis H3C1 H3 clustered histone 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
497 BRCA cuproptosis HSCB HscB mitochondrial iron-sulfur cluster cochaperone 7.65 7.58 -0.01 0.32 0.35 0.0 Detail
498 BRCA cuproptosis HSP70 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
499 BRCA cuproptosis IBA57 iron-sulfur cluster assembly factor IBA57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
500 BRCA cuproptosis IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta 10.29 10.32 0.0 0.62 0.66 0.0 Detail
501 BRCA cuproptosis IL-8 C-X-C motif chemokine ligand 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
502 BRCA cuproptosis INKA1 inka box actin regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
503 BRCA cuproptosis INSL4 insulin like 4 0.18 0.16 -0.16 0.16 0.18 0.0 Detail
504 BRCA cuproptosis INTS6 integrator complex subunit 6 9.69 9.63 -0.01 0.54 0.58 0.0 Detail
505 BRCA cuproptosis IOP1 cytosolic iron-sulfur assembly component 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
506 BRCA cuproptosis ISCU2 iron-sulfur cluster assembly enzyme 0.0 0.0 0.0 0.0 0.0 0.0 Detail
507 BRCA cuproptosis ISD11 LYR motif containing 4 0.0 0.0 0.0 0.0 0.0 0.0 Detail
508 BRCA cuproptosis KAT8 lysine acetyltransferase 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
509 BRCA cuproptosis KMT2A lysine methyltransferase 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
510 BRCA cuproptosis LACTB2 lactamase beta 2 7.84 7.96 0.02 0.18 0.21 0.0 Detail
511 BRCA cuproptosis LASTR lncRNA associated with SART3 regulation of splicing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
512 BRCA cuproptosis LINC02038 long intergenic non-protein coding RNA 2038 0.0 0.0 0.0 0.0 0.0 0.0 Detail
513 BRCA cuproptosis LINC02154 long intergenic non-protein coding RNA 2154 0.0 0.0 0.0 0.0 0.0 0.0 Detail
514 BRCA cuproptosis LINC03085 long intergenic non-protein coding RNA 3085 0.0 0.0 0.0 0.0 0.0 0.0 Detail
515 BRCA cuproptosis LIPT2 lipoyl(octanoyl) transferase 2 4.4 4.4 0.0 0.69 0.72 0.0 Detail
516 BRCA cuproptosis MADD MAP kinase activating death domain 10.33 10.37 0.01 0.31 0.34 0.0 Detail
517 BRCA cuproptosis MARCHF5 membrane associated ring-CH-type finger 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
518 BRCA cuproptosis MAU2 MAU2 sister chromatid cohesion factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
519 BRCA cuproptosis MBTPS2 membrane bound transcription factor peptidase, site 2 9.31 9.34 0.0 0.41 0.45 0.0 Detail
520 BRCA cuproptosis MCMBP minichromosome maintenance complex binding protein 0.0 0.0 0.0 0.0 0.0 0.0 Detail
521 BRCA cuproptosis MCUR1 mitochondrial calcium uniporter regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
522 BRCA cuproptosis MEK1 mitogen-activated protein kinase kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
523 BRCA cuproptosis MEK2 mitogen-activated protein kinase kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
524 BRCA cuproptosis METTL17 methyltransferase like 17 0.0 0.0 0.0 0.0 0.0 0.0 Detail
525 BRCA cuproptosis MPC1 mitochondrial pyruvate carrier 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
526 BRCA cuproptosis MPI mannose phosphate isomerase 9.38 9.29 -0.01 0.17 0.19 0.0 Detail
527 BRCA cuproptosis MRM2 mitochondrial rRNA methyltransferase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
528 BRCA cuproptosis MRPL16 mitochondrial ribosomal protein L16 9.33 9.32 -0.0 0.95 0.95 0.0 Detail
529 BRCA cuproptosis MRPL2 mitochondrial ribosomal protein L2 8.72 8.87 0.02 0.11 0.13 0.0 Detail
530 BRCA cuproptosis MRPL30 mitochondrial ribosomal protein L30 9.79 9.75 -0.0 0.31 0.34 0.0 Detail
531 BRCA cuproptosis MRPL39 mitochondrial ribosomal protein L39 8.57 8.56 -0.0 0.59 0.63 0.0 Detail
532 BRCA cuproptosis MRPL40 mitochondrial ribosomal protein L40 9.13 9.19 0.01 0.42 0.46 0.0 Detail
533 BRCA cuproptosis MRPL57 mitochondrial ribosomal protein L57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
534 BRCA cuproptosis MRPS18C mitochondrial ribosomal protein S18C 8.23 8.17 -0.01 0.11 0.13 0.0 Detail
535 BRCA cuproptosis MRPS22 mitochondrial ribosomal protein S22 8.96 8.91 -0.01 0.04 0.05 0.0 Detail
536 BRCA cuproptosis MRPS9 mitochondrial ribosomal protein S9 8.94 8.98 0.01 0.83 0.85 0.0 Detail
537 BRCA cuproptosis MRRF mitochondrial ribosome recycling factor 8.85 8.96 0.02 0.04 0.05 0.0 Detail
538 BRCA cuproptosis MT1 metallothionein 1A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
539 BRCA cuproptosis MT2 metallothionein 1B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
540 BRCA cuproptosis MT3A unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
541 BRCA cuproptosis MT-CO1 mitochondrially encoded cytochrome c oxidase I 0.0 0.0 0.0 0.0 0.0 0.0 Detail
542 BRCA cuproptosis MT-CO2 mitochondrially encoded cytochrome c oxidase II 0.0 0.0 0.0 0.0 0.0 0.0 Detail
543 BRCA cuproptosis MTCO2P12 MT-CO2 pseudogene 12 0.0 0.0 0.0 0.0 0.0 0.0 Detail
544 BRCA cuproptosis MT-CO3 mitochondrially encoded cytochrome c oxidase III 0.0 0.0 0.0 0.0 0.0 0.0 Detail
545 BRCA cuproptosis MT unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
546 BRCA cuproptosis MTERF1 mitochondrial transcription termination factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
547 BRCA cuproptosis MTFR1L mitochondrial fission regulator 1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
548 BRCA cuproptosis mTOR mechanistic target of rapamycin kinase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
549 BRCA cuproptosis MYO1B myosin IB 11.06 10.9 -0.02 0.1 0.12 0.0 Detail
550 BRCA cuproptosis N6AMT1 N-6 adenine-specific DNA methyltransferase 1 8.22 8.16 -0.01 0.51 0.54 0.0 Detail
551 BRCA cuproptosis NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
552 BRCA cuproptosis NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 10.31 10.35 0.01 0.17 0.2 0.0 Detail
553 BRCA cuproptosis NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 10.67 10.76 0.01 0.39 0.43 0.0 Detail
554 BRCA cuproptosis NFYC nuclear transcription factor Y subunit gamma 10.0 10.01 0.0 0.93 0.93 0.0 Detail
555 BRCA cuproptosis NPL4 NPL4 homolog, ubiquitin recognition factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
556 BRCA cuproptosis OGDHL oxoglutarate dehydrogenase L 2.04 2.23 0.13 0.15 0.18 0.0 Detail
557 BRCA cuproptosis P3H3 prolyl 3-hydroxylase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
558 BRCA cuproptosis p53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
559 BRCA cuproptosis P53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
560 BRCA cuproptosis p97 eukaryotic translation initiation factor 4 gamma 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
561 BRCA cuproptosis PDE12 phosphodiesterase 12 9.23 9.29 0.01 0.19 0.22 0.0 Detail
562 BRCA cuproptosis PDHA pyruvate dehydrogenase E1 subunit alpha 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
563 BRCA cuproptosis PDH pyruvate dehydrogenase phosphatase catalytic subunit 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
564 BRCA cuproptosis PET100 PET100 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
565 BRCA cuproptosis PET117 PET117 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
566 BRCA cuproptosis PFKP phosphofructokinase, platelet 9.48 9.65 0.03 0.19 0.22 0.0 Detail
567 BRCA cuproptosis PHOB unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
568 BRCA cuproptosis PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.0 0.0 0.0 0.0 0.0 0.0 Detail
569 BRCA cuproptosis PITRM1 pitrilysin metallopeptidase 1 10.72 10.78 0.01 0.81 0.83 0.0 Detail
570 BRCA cuproptosis POLR2B RNA polymerase II subunit B 11.18 11.23 0.01 0.12 0.14 0.0 Detail
571 BRCA cuproptosis PPIE peptidylprolyl isomerase E 9.5 9.49 -0.0 0.92 0.93 0.0 Detail
572 BRCA cuproptosis QRSL1 glutaminyl-tRNA amidotransferase subunit QRSL1 8.86 8.9 0.01 0.89 0.9 0.0 Detail
573 BRCA cuproptosis RANTES C-C motif chemokine ligand 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
574 BRCA cuproptosis RCC1L RCC1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
575 BRCA cuproptosis RHOV ras homolog family member V 7.99 8.66 0.11 0.63 0.67 0.0 Detail
576 BRCA cuproptosis RMND1 required for meiotic nuclear division 1 homolog 9.12 9.38 0.04 0.69 0.72 0.0 Detail
577 BRCA cuproptosis RPAIN RPA interacting protein 9.03 8.94 -0.01 0.07 0.09 0.0 Detail
578 BRCA cuproptosis RPL19 ribosomal protein L19 14.11 14.21 0.01 0.88 0.89 0.0 Detail
579 BRCA cuproptosis RPLP0 ribosomal protein lateral stalk subunit P0 14.49 14.45 -0.0 0.67 0.7 0.0 Detail
580 BRCA cuproptosis RPS19 ribosomal protein S19 13.37 13.52 0.02 0.22 0.25 0.0 Detail
581 BRCA cuproptosis S6K1 ribosomal protein S6 kinase B1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
582 BRCA cuproptosis SCAP SREBF chaperone 10.79 10.71 -0.01 0.09 0.11 0.0 Detail
583 BRCA cuproptosis SDHA succinate dehydrogenase complex flavoprotein subunit A 11.09 11.16 0.01 0.14 0.16 0.0 Detail
584 BRCA cuproptosis SDHB succinate dehydrogenase complex iron sulfur subunit B 10.28 10.25 -0.0 0.78 0.8 0.0 Detail
585 BRCA cuproptosis SEC14L2 SEC14 like lipid binding 2 9.59 9.8 0.03 0.72 0.74 0.0 Detail
586 BRCA cuproptosis SEPTIN1 septin 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
587 BRCA cuproptosis SGF29 SAGA complex associated factor 29 0.0 0.0 0.0 0.0 0.0 0.0 Detail
588 BRCA cuproptosis SLC25A51 solute carrier family 25 member 51 0.0 0.0 0.0 0.0 0.0 0.0 Detail
589 BRCA cuproptosis SLC30A10 solute carrier family 30 member 10 0.42 0.44 0.06 0.04 0.05 0.0 Detail
590 BRCA cuproptosis SLC33A1 solute carrier family 33 member 1 9.23 9.32 0.01 0.25 0.28 0.0 Detail
591 BRCA cuproptosis SLC52A2 solute carrier family 52 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
592 BRCA cuproptosis SMAD3-AS1 SMAD3 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
593 BRCA cuproptosis sp1 Sp1 transcription factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
594 BRCA cuproptosis SPARC secreted protein acidic and cysteine rich 15.26 15.41 0.01 0.13 0.15 0.0 Detail
595 BRCA cuproptosis SPDYE1 speedy/RINGO cell cycle regulator family member E1 3.3 3.22 -0.04 0.19 0.21 0.0 Detail
596 BRCA cuproptosis STEAP4 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
597 BRCA cuproptosis STEAP STEAP family member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
598 BRCA cuproptosis TEDC1 tubulin epsilon and delta complex 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
599 BRCA cuproptosis TEFM transcription elongation factor, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 Detail
600 BRCA cuproptosis TFAM transcription factor A, mitochondrial 9.24 9.21 -0.0 0.47 0.51 0.0 Detail
601 BRCA cuproptosis TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
602 BRCA cuproptosis TMEM191B transmembrane protein 191B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
603 BRCA cuproptosis TP53 tumor protein p53 10.46 10.51 0.01 0.33 0.36 0.0 Detail
604 BRCA cuproptosis TRAPPC11 trafficking protein particle complex subunit 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
605 BRCA cuproptosis TRIM32 tripartite motif containing 32 9.03 8.94 -0.01 0.34 0.37 0.0 Detail
606 BRCA cuproptosis TRRAP transformation/transcription domain associated protein 10.94 10.94 0.0 0.95 0.95 0.0 Detail
607 BRCA cuproptosis TWNK twinkle mtDNA helicase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
608 BRCA cuproptosis TYR tyrosinase 0.18 0.21 0.19 0.97 0.98 0.0 Detail
609 BRCA cuproptosis U2SURP U2 snRNP associated SURP domain containing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
610 BRCA cuproptosis UlK1 unc-51 like autophagy activating kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
611 BRCA cuproptosis UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
612 BRCA cuproptosis UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
613 BRCA cuproptosis USE1 unconventional SNARE in the ER 1 8.02 8.05 0.01 0.98 0.98 0.0 Detail
614 BRCA cuproptosis UTP25 UTP25 small subunit processome component 0.0 0.0 0.0 0.0 0.0 0.0 Detail
615 BRCA cuproptosis xCT solute carrier family 7 member 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
616 BRCA cuproptosis YAE1 YAE1 maturation factor of ABCE1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
617 BRCA cuproptosis YEATS2 YEATS domain containing 2 9.88 9.89 0.0 0.33 0.37 0.0 Detail
618 BRCA cuproptosis ZBTB11 zinc finger and BTB domain containing 11 9.51 9.43 -0.01 0.13 0.15 0.0 Detail
619 BRCA cuproptosis ZFAT zinc finger and AT-hook domain containing 8.11 8.19 0.01 0.16 0.18 0.0 Detail
620 BRCA cuproptosis ZKSCAN5 zinc finger with KRAB and SCAN domains 5 8.59 8.65 0.01 0.07 0.09 0.0 Detail

Ensemble learning for BRCA based on specific cuproptosis gene regulaors.