Disease associated with RCD disease & gene list




COAD specific anoikis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 COAD anoikis PDK4 pyruvate dehydrogenase kinase 4 11.49 8.09 -0.51 0.0 0.0 100.0 Detail
2 COAD anoikis E2F1 E2F transcription factor 1 7.64 9.21 0.27 0.0 0.0 92.92 Detail
3 COAD anoikis BCL2 BCL2 apoptosis regulator 9.13 7.16 -0.35 0.0 0.0 91.63 Detail
4 COAD anoikis BCL2L1 BCL2 like 1 10.99 11.95 0.12 0.0 0.0 84.27 Detail
5 COAD anoikis TFDP1 transcription factor Dp-1 10.88 11.68 0.1 0.0 0.0 77.91 Detail
6 COAD anoikis PTRH2 peptidyl-tRNA hydrolase 2 8.19 8.97 0.13 0.0 0.0 76.37 Detail
7 COAD anoikis MYBBP1A MYB binding protein 1a 9.6 10.47 0.12 0.0 0.0 73.22 Detail
8 COAD anoikis CAV1 caveolin 1 11.2 9.42 -0.25 0.0 0.0 72.26 Detail
9 COAD anoikis CHEK2 checkpoint kinase 2 7.73 8.56 0.15 0.0 0.0 71.78 Detail
10 COAD anoikis PTK2 protein tyrosine kinase 2 10.76 11.23 0.06 0.0 0.0 67.24 Detail
11 COAD anoikis ANKRD13C ankyrin repeat domain 13C 9.21 8.86 -0.06 0.0 0.0 52.92 Detail
12 COAD anoikis BMF Bcl2 modifying factor 9.36 8.3 -0.17 0.0 0.0 49.26 Detail
13 COAD anoikis NTRK2 neurotrophic receptor tyrosine kinase 2 8.1 5.86 -0.47 0.0 0.0 45.0 Detail
14 COAD anoikis TLE1 TLE family member 1, transcriptional corepressor 10.11 9.55 -0.08 0.0 0.0 40.46 Detail
15 COAD anoikis SNAI2 snail family transcriptional repressor 2 7.53 6.83 -0.14 0.0 0.0 26.45 Detail
16 COAD anoikis DAPK2 death associated protein kinase 2 9.3 8.56 -0.12 0.0 0.0 24.77 Detail
17 COAD anoikis MAP3K7 mitogen-activated protein kinase kinase kinase 7 9.0 9.14 0.02 0.0 0.0 13.77 Detail
18 COAD anoikis MCL1 MCL1 apoptosis regulator, BCL2 family member 13.0 12.68 -0.04 0.0 0.01 7.6 Detail
19 COAD anoikis BRMS1 BRMS1 transcriptional repressor and anoikis regulator 9.96 10.12 0.02 0.02 0.02 0.12 Detail
20 COAD anoikis CRYBA1 crystallin beta A1 0.07 0.11 0.6 0.34 0.39 0.0 Detail
21 COAD anoikis IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 8.78 8.81 0.01 0.71 0.73 0.0 Detail
22 COAD anoikis ITGA5 integrin subunit alpha 5 10.6 10.46 -0.02 0.91 0.91 0.0 Detail
23 COAD anoikis ITGB1 integrin subunit beta 1 13.25 13.27 0.0 0.7 0.73 0.0 Detail
24 COAD anoikis NOTCH1 notch receptor 1 11.07 11.38 0.04 0.02 0.02 0.0 Detail
25 COAD anoikis PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 8.2 8.08 -0.02 0.11 0.15 0.0 Detail
26 COAD anoikis SIK1 salt inducible kinase 1 9.49 9.76 0.04 0.26 0.32 0.0 Detail
27 COAD anoikis SRC SRC proto-oncogene, non-receptor tyrosine kinase 11.27 11.38 0.01 0.15 0.2 0.0 Detail
28 COAD anoikis STK11 serine/threonine kinase 11 10.37 10.29 -0.01 0.26 0.32 0.0 Detail
29 COAD anoikis TSC2 TSC complex subunit 2 10.78 10.74 -0.01 0.42 0.47 0.0 Detail

Ensemble learning for COAD based on specific anoikis gene regulaors.