Disease associated with RCD disease & gene list




ESCA specific anoikis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 ESCA anoikis CHEK2 checkpoint kinase 2 5.78 7.73 0.42 0.0 0.0 100.0 Detail
2 ESCA anoikis E2F1 E2F transcription factor 1 6.81 8.87 0.38 0.0 0.0 88.46 Detail
3 ESCA anoikis PTRH2 peptidyl-tRNA hydrolase 2 7.66 8.59 0.17 0.0 0.0 77.97 Detail
4 ESCA anoikis PDK4 pyruvate dehydrogenase kinase 4 12.88 8.41 -0.62 0.0 0.0 73.78 Detail
5 ESCA anoikis TFDP1 transcription factor Dp-1 10.27 11.32 0.14 0.0 0.0 71.68 Detail
6 ESCA anoikis TSC2 TSC complex subunit 2 11.7 11.04 -0.08 0.0 0.0 69.23 Detail
7 ESCA anoikis BRMS1 BRMS1 transcriptional repressor and anoikis regulator 8.66 9.59 0.15 0.0 0.0 48.95 Detail
8 ESCA anoikis BCL2 BCL2 apoptosis regulator 8.59 7.25 -0.24 0.0 0.01 31.47 Detail
9 ESCA anoikis MYBBP1A MYB binding protein 1a 10.07 10.73 0.09 0.0 0.01 30.77 Detail
10 ESCA anoikis TLE1 TLE family member 1, transcriptional corepressor 10.42 9.71 -0.1 0.0 0.01 24.83 Detail
11 ESCA anoikis IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 8.43 8.88 0.07 0.0 0.01 22.73 Detail
12 ESCA anoikis MAP3K7 mitogen-activated protein kinase kinase kinase 7 9.2 9.48 0.04 0.01 0.02 13.29 Detail
13 ESCA anoikis ANKRD13C ankyrin repeat domain 13C 9.44 9.18 -0.04 0.02 0.04 0.0 Detail
14 ESCA anoikis BCL2L1 BCL2 like 1 10.97 11.23 0.03 0.36 0.47 0.0 Detail
15 ESCA anoikis BMF Bcl2 modifying factor 8.36 8.5 0.02 0.87 0.87 0.0 Detail
16 ESCA anoikis CAV1 caveolin 1 11.48 10.95 -0.07 0.32 0.47 0.0 Detail
17 ESCA anoikis CRYBA1 crystallin beta A1 0.69 0.33 -1.06 0.06 0.1 0.0 Detail
18 ESCA anoikis DAPK2 death associated protein kinase 2 7.16 7.03 -0.03 0.74 0.76 0.0 Detail
19 ESCA anoikis ITGA5 integrin subunit alpha 5 12.08 11.57 -0.06 0.39 0.49 0.0 Detail
20 ESCA anoikis ITGB1 integrin subunit beta 1 13.34 13.6 0.03 0.11 0.18 0.0 Detail
21 ESCA anoikis MCL1 MCL1 apoptosis regulator, BCL2 family member 13.5 13.35 -0.02 0.56 0.61 0.0 Detail
22 ESCA anoikis NOTCH1 notch receptor 1 11.02 11.89 0.11 0.03 0.06 0.0 Detail
23 ESCA anoikis NTRK2 neurotrophic receptor tyrosine kinase 2 9.12 8.45 -0.11 0.43 0.52 0.0 Detail
24 ESCA anoikis PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 9.31 9.5 0.03 0.47 0.53 0.0 Detail
25 ESCA anoikis PTK2 protein tyrosine kinase 2 11.01 11.38 0.05 0.05 0.09 0.0 Detail
26 ESCA anoikis SIK1 salt inducible kinase 1 11.18 10.88 -0.04 0.47 0.53 0.0 Detail
27 ESCA anoikis SNAI2 snail family transcriptional repressor 2 8.03 8.87 0.14 0.25 0.38 0.0 Detail
28 ESCA anoikis SRC SRC proto-oncogene, non-receptor tyrosine kinase 11.14 11.52 0.05 0.07 0.12 0.0 Detail
29 ESCA anoikis STK11 serine/threonine kinase 11 10.31 10.12 -0.03 0.34 0.47 0.0 Detail

Ensemble learning for ESCA based on specific anoikis gene regulaors.