Disease specific cell death gene regulator search
Search Results:
ESCA specific anoikis gene regulaors.
Different color in column1 means high , low , non-diff expressed gene in disease.
NO. | Disease | CellDeathType | Genesymbol | Fullname | Control_mean | Disease_mean | log2FC | pvalue | padj | Weight | Detail |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | ESCA | anoikis | CHEK2 | checkpoint kinase 2 | 5.78 | 7.73 | 0.42 | 0.0 | 0.0 | 100.0 | Detail |
2 | ESCA | anoikis | E2F1 | E2F transcription factor 1 | 6.81 | 8.87 | 0.38 | 0.0 | 0.0 | 88.46 | Detail |
3 | ESCA | anoikis | PTRH2 | peptidyl-tRNA hydrolase 2 | 7.66 | 8.59 | 0.17 | 0.0 | 0.0 | 77.97 | Detail |
4 | ESCA | anoikis | PDK4 | pyruvate dehydrogenase kinase 4 | 12.88 | 8.41 | -0.62 | 0.0 | 0.0 | 73.78 | Detail |
5 | ESCA | anoikis | TFDP1 | transcription factor Dp-1 | 10.27 | 11.32 | 0.14 | 0.0 | 0.0 | 71.68 | Detail |
6 | ESCA | anoikis | TSC2 | TSC complex subunit 2 | 11.7 | 11.04 | -0.08 | 0.0 | 0.0 | 69.23 | Detail |
7 | ESCA | anoikis | BRMS1 | BRMS1 transcriptional repressor and anoikis regulator | 8.66 | 9.59 | 0.15 | 0.0 | 0.0 | 48.95 | Detail |
8 | ESCA | anoikis | BCL2 | BCL2 apoptosis regulator | 8.59 | 7.25 | -0.24 | 0.0 | 0.01 | 31.47 | Detail |
9 | ESCA | anoikis | MYBBP1A | MYB binding protein 1a | 10.07 | 10.73 | 0.09 | 0.0 | 0.01 | 30.77 | Detail |
10 | ESCA | anoikis | TLE1 | TLE family member 1, transcriptional corepressor | 10.42 | 9.71 | -0.1 | 0.0 | 0.01 | 24.83 | Detail |
11 | ESCA | anoikis | IKBKG | inhibitor of nuclear factor kappa B kinase regulatory subunit gamma | 8.43 | 8.88 | 0.07 | 0.0 | 0.01 | 22.73 | Detail |
12 | ESCA | anoikis | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 9.2 | 9.48 | 0.04 | 0.01 | 0.02 | 13.29 | Detail |
13 | ESCA | anoikis | ANKRD13C | ankyrin repeat domain 13C | 9.44 | 9.18 | -0.04 | 0.02 | 0.04 | 0.0 | Detail |
14 | ESCA | anoikis | BCL2L1 | BCL2 like 1 | 10.97 | 11.23 | 0.03 | 0.36 | 0.47 | 0.0 | Detail |
15 | ESCA | anoikis | BMF | Bcl2 modifying factor | 8.36 | 8.5 | 0.02 | 0.87 | 0.87 | 0.0 | Detail |
16 | ESCA | anoikis | CAV1 | caveolin 1 | 11.48 | 10.95 | -0.07 | 0.32 | 0.47 | 0.0 | Detail |
17 | ESCA | anoikis | CRYBA1 | crystallin beta A1 | 0.69 | 0.33 | -1.06 | 0.06 | 0.1 | 0.0 | Detail |
18 | ESCA | anoikis | DAPK2 | death associated protein kinase 2 | 7.16 | 7.03 | -0.03 | 0.74 | 0.76 | 0.0 | Detail |
19 | ESCA | anoikis | ITGA5 | integrin subunit alpha 5 | 12.08 | 11.57 | -0.06 | 0.39 | 0.49 | 0.0 | Detail |
20 | ESCA | anoikis | ITGB1 | integrin subunit beta 1 | 13.34 | 13.6 | 0.03 | 0.11 | 0.18 | 0.0 | Detail |
21 | ESCA | anoikis | MCL1 | MCL1 apoptosis regulator, BCL2 family member | 13.5 | 13.35 | -0.02 | 0.56 | 0.61 | 0.0 | Detail |
22 | ESCA | anoikis | NOTCH1 | notch receptor 1 | 11.02 | 11.89 | 0.11 | 0.03 | 0.06 | 0.0 | Detail |
23 | ESCA | anoikis | NTRK2 | neurotrophic receptor tyrosine kinase 2 | 9.12 | 8.45 | -0.11 | 0.43 | 0.52 | 0.0 | Detail |
24 | ESCA | anoikis | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9.31 | 9.5 | 0.03 | 0.47 | 0.53 | 0.0 | Detail |
25 | ESCA | anoikis | PTK2 | protein tyrosine kinase 2 | 11.01 | 11.38 | 0.05 | 0.05 | 0.09 | 0.0 | Detail |
26 | ESCA | anoikis | SIK1 | salt inducible kinase 1 | 11.18 | 10.88 | -0.04 | 0.47 | 0.53 | 0.0 | Detail |
27 | ESCA | anoikis | SNAI2 | snail family transcriptional repressor 2 | 8.03 | 8.87 | 0.14 | 0.25 | 0.38 | 0.0 | Detail |
28 | ESCA | anoikis | SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 11.14 | 11.52 | 0.05 | 0.07 | 0.12 | 0.0 | Detail |
29 | ESCA | anoikis | STK11 | serine/threonine kinase 11 | 10.31 | 10.12 | -0.03 | 0.34 | 0.47 | 0.0 | Detail |
Ensemble learning visualization:
Ensemble learning for ESCA based on specific anoikis gene regulaors.

