Disease associated with RCD disease & gene list




ESCA specific cuproptosis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 ESCA cuproptosis CDKN3 cyclin dependent kinase inhibitor 3 5.09 8.21 0.69 0.0 0.0 100.0 Detail
2 ESCA cuproptosis MTBP MDM2 binding protein 5.56 7.75 0.48 0.0 0.0 95.55 Detail
3 ESCA cuproptosis ANLN anillin, actin binding protein 7.94 11.15 0.49 0.0 0.0 93.15 Detail
4 ESCA cuproptosis PRC1 protein regulator of cytokinesis 1 7.98 10.56 0.4 0.0 0.0 92.47 Detail
5 ESCA cuproptosis TRAIP TRAF interacting protein 4.59 6.56 0.52 0.0 0.0 91.78 Detail
6 ESCA cuproptosis HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 13.04 13.77 0.08 0.0 0.0 91.44 Detail
7 ESCA cuproptosis CENPW centromere protein W 5.5 7.88 0.52 0.0 0.0 91.1 Detail
8 ESCA cuproptosis FOXM1 forkhead box M1 7.73 11.14 0.53 0.0 0.0 90.41 Detail
9 ESCA cuproptosis POLD1 DNA polymerase delta 1, catalytic subunit 8.04 9.54 0.25 0.0 0.0 90.41 Detail
10 ESCA cuproptosis ISG15 ISG15 ubiquitin like modifier 7.47 10.15 0.44 0.0 0.0 89.38 Detail
11 ESCA cuproptosis CDK1 cyclin dependent kinase 1 6.97 10.3 0.56 0.0 0.0 88.36 Detail
12 ESCA cuproptosis MT1M metallothionein 1M 8.22 3.61 -1.19 0.0 0.0 85.62 Detail
13 ESCA cuproptosis BRCA1 BRCA1 DNA repair associated 7.65 9.66 0.34 0.0 0.0 85.1 Detail
14 ESCA cuproptosis MT1A metallothionein 1A 6.89 2.61 -1.4 0.0 0.0 83.9 Detail
15 ESCA cuproptosis WDR12 WD repeat domain 12 7.84 8.91 0.18 0.0 0.0 81.85 Detail
16 ESCA cuproptosis DNA2 DNA replication helicase/nuclease 2 5.83 7.95 0.45 0.0 0.0 81.51 Detail
17 ESCA cuproptosis DTYMK deoxythymidylate kinase 7.52 8.93 0.25 0.0 0.0 78.42 Detail
18 ESCA cuproptosis MCM5 minichromosome maintenance complex component 5 9.2 10.85 0.24 0.0 0.0 78.08 Detail
19 ESCA cuproptosis PSMA6 proteasome 20S subunit alpha 6 9.59 10.52 0.13 0.0 0.0 77.74 Detail
20 ESCA cuproptosis ETFDH electron transfer flavoprotein dehydrogenase 9.97 8.55 -0.22 0.0 0.0 77.05 Detail
21 ESCA cuproptosis CCL20 C-C motif chemokine ligand 20 3.63 8.5 1.23 0.0 0.0 75.34 Detail
22 ESCA cuproptosis PHF5A PHD finger protein 5A 7.76 8.52 0.13 0.0 0.0 75.34 Detail
23 ESCA cuproptosis ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 9.6 10.59 0.14 0.0 0.0 74.32 Detail
24 ESCA cuproptosis AP1S1 adaptor related protein complex 1 subunit sigma 1 7.98 9.25 0.21 0.0 0.0 73.63 Detail
25 ESCA cuproptosis MRPL14 mitochondrial ribosomal protein L14 8.33 9.47 0.19 0.0 0.0 73.29 Detail
26 ESCA cuproptosis MYO1B myosin IB 10.14 11.67 0.2 0.0 0.0 72.26 Detail
27 ESCA cuproptosis SLC25A26 solute carrier family 25 member 26 8.54 7.79 -0.13 0.0 0.0 70.89 Detail
28 ESCA cuproptosis FGD6 FYVE, RhoGEF and PH domain containing 6 8.7 10.26 0.24 0.0 0.0 70.21 Detail
29 ESCA cuproptosis DAXX death domain associated protein 9.68 10.3 0.09 0.0 0.0 66.78 Detail
30 ESCA cuproptosis PRKDC protein kinase, DNA-activated, catalytic subunit 12.1 13.1 0.11 0.0 0.0 66.78 Detail
31 ESCA cuproptosis ACO2 aconitase 2 12.57 11.5 -0.13 0.0 0.0 66.44 Detail
32 ESCA cuproptosis ISCU iron-sulfur cluster assembly enzyme 10.81 9.98 -0.12 0.0 0.0 66.44 Detail
33 ESCA cuproptosis MRPL13 mitochondrial ribosomal protein L13 8.59 9.49 0.14 0.0 0.0 66.44 Detail
34 ESCA cuproptosis PPAT phosphoribosyl pyrophosphate amidotransferase 7.71 8.89 0.21 0.0 0.0 66.44 Detail
35 ESCA cuproptosis PDHB pyruvate dehydrogenase E1 subunit beta 10.08 9.3 -0.12 0.0 0.0 65.75 Detail
36 ESCA cuproptosis CSTF3 cleavage stimulation factor subunit 3 8.62 9.42 0.13 0.0 0.0 65.41 Detail
37 ESCA cuproptosis FADD Fas associated via death domain 8.44 9.96 0.24 0.0 0.0 64.38 Detail
38 ESCA cuproptosis NOP2 NOP2 nucleolar protein 9.09 10.16 0.16 0.0 0.0 63.01 Detail
39 ESCA cuproptosis GTPBP4 GTP binding protein 4 9.69 10.46 0.11 0.0 0.0 59.25 Detail
40 ESCA cuproptosis TAF4 TATA-box binding protein associated factor 4 9.16 9.81 0.1 0.0 0.0 59.25 Detail
41 ESCA cuproptosis CNN1 calponin 1 12.29 8.29 -0.57 0.0 0.0 57.53 Detail
42 ESCA cuproptosis TOP1MT DNA topoisomerase I mitochondrial 8.2 9.51 0.21 0.0 0.0 57.19 Detail
43 ESCA cuproptosis GFRA3 GDNF family receptor alpha 3 7.0 4.13 -0.76 0.0 0.0 52.4 Detail
44 ESCA cuproptosis YARS2 tyrosyl-tRNA synthetase 2 7.73 8.5 0.14 0.0 0.0 52.4 Detail
45 ESCA cuproptosis ACLY ATP citrate lyase 11.28 11.99 0.09 0.0 0.0 52.05 Detail
46 ESCA cuproptosis MT1X metallothionein 1X 11.03 8.85 -0.32 0.0 0.0 51.71 Detail
47 ESCA cuproptosis TMEM199 transmembrane protein 199 7.96 8.47 0.09 0.0 0.0 51.37 Detail
48 ESCA cuproptosis AOC3 amine oxidase copper containing 3 10.94 8.17 -0.42 0.0 0.0 50.0 Detail
49 ESCA cuproptosis HSPD1 heat shock protein family D (Hsp60) member 1 12.01 12.88 0.1 0.0 0.0 48.97 Detail
50 ESCA cuproptosis RUVBL2 RuvB like AAA ATPase 2 9.92 10.76 0.12 0.0 0.0 48.97 Detail
51 ESCA cuproptosis UBE2I ubiquitin conjugating enzyme E2 I 9.99 10.62 0.09 0.0 0.0 47.43 Detail
52 ESCA cuproptosis YEATS2 YEATS domain containing 2 9.84 10.86 0.14 0.0 0.0 47.26 Detail
53 ESCA cuproptosis CDK5RAP1 CDK5 regulatory subunit associated protein 1 8.2 8.77 0.1 0.0 0.0 46.23 Detail
54 ESCA cuproptosis BUD31 BUD31 homolog 9.47 10.2 0.11 0.0 0.0 45.89 Detail
55 ESCA cuproptosis NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 11.36 10.67 -0.09 0.0 0.0 45.21 Detail
56 ESCA cuproptosis SCO2 synthesis of cytochrome C oxidase 2 7.74 8.78 0.18 0.0 0.0 44.86 Detail
57 ESCA cuproptosis UBAP2L ubiquitin associated protein 2 like 11.73 12.17 0.05 0.0 0.0 43.84 Detail
58 ESCA cuproptosis CENPJ centromere protein J 7.12 8.24 0.21 0.0 0.0 43.49 Detail
59 ESCA cuproptosis DBT dihydrolipoamide branched chain transacylase E2 10.83 9.49 -0.19 0.0 0.0 43.15 Detail
60 ESCA cuproptosis UBE2D1 ubiquitin conjugating enzyme E2 D1 8.72 9.37 0.1 0.0 0.0 43.15 Detail
61 ESCA cuproptosis CAPRIN1 cell cycle associated protein 1 12.21 12.75 0.06 0.0 0.0 42.47 Detail
62 ESCA cuproptosis SLC25A3 solute carrier family 25 member 3 13.14 12.68 -0.05 0.0 0.0 40.41 Detail
63 ESCA cuproptosis HNRNPU heterogeneous nuclear ribonucleoprotein U 12.78 13.26 0.05 0.0 0.01 40.07 Detail
64 ESCA cuproptosis PDZD4 PDZ domain containing 4 7.62 4.9 -0.64 0.0 0.01 39.73 Detail
65 ESCA cuproptosis MT1G metallothionein 1G 10.86 7.07 -0.62 0.0 0.01 39.38 Detail
66 ESCA cuproptosis DBR1 debranching RNA lariats 1 8.23 8.92 0.12 0.0 0.01 39.04 Detail
67 ESCA cuproptosis NTHL1 nth like DNA glycosylase 1 6.71 7.42 0.15 0.0 0.01 39.04 Detail
68 ESCA cuproptosis SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit 10.9 11.49 0.08 0.0 0.01 38.7 Detail
69 ESCA cuproptosis PSMB5 proteasome 20S subunit beta 5 9.99 10.62 0.09 0.0 0.01 38.36 Detail
70 ESCA cuproptosis COX7C cytochrome c oxidase subunit 7C 11.04 10.44 -0.08 0.0 0.01 38.01 Detail
71 ESCA cuproptosis AHR aryl hydrocarbon receptor 11.43 12.32 0.11 0.0 0.01 37.67 Detail
72 ESCA cuproptosis TAF6L TATA-box binding protein associated factor 6 like 7.58 8.15 0.1 0.0 0.01 37.67 Detail
73 ESCA cuproptosis GSS glutathione synthetase 9.34 10.11 0.11 0.0 0.01 35.62 Detail
74 ESCA cuproptosis HAUS5 HAUS augmin like complex subunit 5 7.9 8.57 0.12 0.0 0.01 35.62 Detail
75 ESCA cuproptosis RPL3 ribosomal protein L3 14.62 13.92 -0.07 0.0 0.01 35.62 Detail
76 ESCA cuproptosis MAN2C1 mannosidase alpha class 2C member 1 9.94 9.44 -0.07 0.0 0.01 35.27 Detail
77 ESCA cuproptosis PLOD1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 10.57 11.55 0.13 0.0 0.01 34.93 Detail
78 ESCA cuproptosis POLR2K RNA polymerase II, I and III subunit K 9.49 10.04 0.08 0.0 0.01 32.88 Detail
79 ESCA cuproptosis ABCE1 ATP binding cassette subfamily E member 1 10.32 10.9 0.08 0.0 0.01 32.53 Detail
80 ESCA cuproptosis N6AMT1 N-6 adenine-specific DNA methyltransferase 1 7.62 6.88 -0.15 0.0 0.01 32.53 Detail
81 ESCA cuproptosis LOXL2 lysyl oxidase like 2 8.4 10.35 0.3 0.0 0.01 31.85 Detail
82 ESCA cuproptosis RAD9A RAD9 checkpoint clamp component A 7.29 8.17 0.17 0.0 0.01 31.16 Detail
83 ESCA cuproptosis CCDC28B coiled-coil domain containing 28B 4.91 5.89 0.26 0.0 0.01 30.48 Detail
84 ESCA cuproptosis TNF tumor necrosis factor 2.69 4.6 0.77 0.0 0.01 30.14 Detail
85 ESCA cuproptosis MAD2L2 mitotic arrest deficient 2 like 2 8.2 8.95 0.13 0.0 0.01 29.79 Detail
86 ESCA cuproptosis CHMP4B charged multivesicular body protein 4B 10.46 10.97 0.07 0.0 0.01 29.11 Detail
87 ESCA cuproptosis CYP2D6 cytochrome P450 family 2 subfamily D member 6 2.06 3.54 0.78 0.0 0.01 28.42 Detail
88 ESCA cuproptosis PGK1 phosphoglycerate kinase 1 12.05 12.9 0.1 0.0 0.01 28.42 Detail
89 ESCA cuproptosis ACO1 aconitase 1 10.86 9.82 -0.15 0.0 0.01 28.08 Detail
90 ESCA cuproptosis BCL2 BCL2 apoptosis regulator 8.59 7.25 -0.24 0.0 0.01 27.74 Detail
91 ESCA cuproptosis CCDC137 coiled-coil domain containing 137 8.41 9.13 0.12 0.0 0.01 27.74 Detail
92 ESCA cuproptosis UQCRC2 ubiquinol-cytochrome c reductase core protein 2 11.9 11.36 -0.07 0.0 0.01 27.74 Detail
93 ESCA cuproptosis SLC25A32 solute carrier family 25 member 32 8.92 9.57 0.1 0.0 0.01 27.4 Detail
94 ESCA cuproptosis MRPL2 mitochondrial ribosomal protein L2 8.27 8.95 0.11 0.0 0.01 27.05 Detail
95 ESCA cuproptosis UBA2 ubiquitin like modifier activating enzyme 2 10.71 11.19 0.06 0.0 0.01 27.05 Detail
96 ESCA cuproptosis MRPL36 mitochondrial ribosomal protein L36 8.04 8.75 0.12 0.0 0.01 26.37 Detail
97 ESCA cuproptosis NDUFS6 NADH:ubiquinone oxidoreductase subunit S6 9.12 9.76 0.1 0.0 0.01 26.03 Detail
98 ESCA cuproptosis ULK1 unc-51 like autophagy activating kinase 1 11.42 10.72 -0.09 0.0 0.01 26.03 Detail
99 ESCA cuproptosis GLS glutaminase 10.36 11.3 0.13 0.0 0.01 24.32 Detail
100 ESCA cuproptosis SPATA5 AFG2 AAA ATPase homolog A 7.79 8.46 0.12 0.0 0.01 24.32 Detail
101 ESCA cuproptosis MRPS30 mitochondrial ribosomal protein S30 8.77 9.3 0.08 0.0 0.01 22.43 Detail
102 ESCA cuproptosis MT2A metallothionein 2A 12.12 10.58 -0.2 0.0 0.01 22.26 Detail
103 ESCA cuproptosis ATF4 activating transcription factor 4 12.64 12.06 -0.07 0.0 0.01 22.26 Detail
104 ESCA cuproptosis RANGAP1 Ran GTPase activating protein 1 10.84 11.54 0.09 0.0 0.01 22.26 Detail
105 ESCA cuproptosis RIPK1 receptor interacting serine/threonine kinase 1 10.29 9.88 -0.06 0.0 0.01 21.92 Detail
106 ESCA cuproptosis C1QBP complement C1q binding protein 10.25 10.98 0.1 0.0 0.02 20.89 Detail
107 ESCA cuproptosis HEPHL1 hephaestin like 1 3.1 6.49 1.07 0.0 0.02 20.72 Detail
108 ESCA cuproptosis LACTB2 lactamase beta 2 8.03 8.98 0.16 0.0 0.02 20.55 Detail
109 ESCA cuproptosis DIP2B disco interacting protein 2 homolog B 10.73 11.48 0.1 0.0 0.02 19.86 Detail
110 ESCA cuproptosis MRPS12 mitochondrial ribosomal protein S12 8.39 9.07 0.11 0.0 0.02 19.86 Detail
111 ESCA cuproptosis MRPL17 mitochondrial ribosomal protein L17 8.82 9.52 0.11 0.0 0.02 19.52 Detail
112 ESCA cuproptosis FPGS folylpolyglutamate synthase 9.62 10.17 0.08 0.0 0.02 19.18 Detail
113 ESCA cuproptosis MRPL21 mitochondrial ribosomal protein L21 8.32 9.16 0.14 0.0 0.02 18.84 Detail
114 ESCA cuproptosis NFE2L2 NFE2 like bZIP transcription factor 2 13.0 12.2 -0.09 0.0 0.02 18.49 Detail
115 ESCA cuproptosis POLE DNA polymerase epsilon, catalytic subunit 10.12 10.65 0.07 0.0 0.02 18.49 Detail
116 ESCA cuproptosis CDC27 cell division cycle 27 10.3 10.7 0.05 0.0 0.02 18.15 Detail
117 ESCA cuproptosis MT3 metallothionein 3 3.0 0.95 -1.65 0.0 0.02 17.47 Detail
118 ESCA cuproptosis CAT catalase 11.0 10.26 -0.1 0.0 0.02 17.47 Detail
119 ESCA cuproptosis MRPL12 mitochondrial ribosomal protein L12 9.13 9.84 0.11 0.0 0.02 17.12 Detail
120 ESCA cuproptosis SLC30A10 solute carrier family 30 member 10 0.57 2.47 2.13 0.0 0.02 16.78 Detail
121 ESCA cuproptosis MLKL mixed lineage kinase domain like pseudokinase 7.99 8.62 0.11 0.01 0.02 15.75 Detail
122 ESCA cuproptosis ARF1 ADP ribosylation factor 1 12.96 13.32 0.04 0.01 0.02 15.41 Detail
123 ESCA cuproptosis COPS5 COP9 signalosome subunit 5 9.51 9.91 0.06 0.01 0.02 15.41 Detail
124 ESCA cuproptosis PDE12 phosphodiesterase 12 10.01 9.56 -0.07 0.01 0.02 15.41 Detail
125 ESCA cuproptosis TRRAP transformation/transcription domain associated protein 11.26 11.74 0.06 0.01 0.02 15.41 Detail
126 ESCA cuproptosis ACD ACD shelterin complex subunit and telomerase recruitment factor 8.25 8.8 0.09 0.01 0.02 15.07 Detail
127 ESCA cuproptosis TKT transketolase 11.52 12.39 0.1 0.01 0.02 15.07 Detail
128 ESCA cuproptosis PRDX1 peroxiredoxin 1 12.05 12.72 0.08 0.01 0.02 14.73 Detail
129 ESCA cuproptosis COQ2 coenzyme Q2, polyprenyltransferase 7.25 7.85 0.11 0.01 0.02 14.38 Detail
130 ESCA cuproptosis HMBS hydroxymethylbilane synthase 7.59 8.4 0.15 0.01 0.02 14.38 Detail
131 ESCA cuproptosis MRPL51 mitochondrial ribosomal protein L51 9.36 9.89 0.08 0.01 0.02 14.38 Detail
132 ESCA cuproptosis IDH2 isocitrate dehydrogenase (NADP(+)) 2 12.25 11.11 -0.14 0.01 0.02 13.7 Detail
133 ESCA cuproptosis MRRF mitochondrial ribosome recycling factor 8.91 9.49 0.09 0.01 0.02 13.36 Detail
134 ESCA cuproptosis NUP133 nucleoporin 133 9.86 10.19 0.05 0.01 0.03 12.33 Detail
135 ESCA cuproptosis MAP2K1 mitogen-activated protein kinase kinase 1 9.94 10.29 0.05 0.01 0.03 12.16 Detail
136 ESCA cuproptosis SLC16A1 solute carrier family 16 member 1 10.08 11.09 0.14 0.01 0.03 11.64 Detail
137 ESCA cuproptosis SURF1 SURF1 cytochrome c oxidase assembly factor 9.41 8.78 -0.1 0.01 0.03 11.64 Detail
138 ESCA cuproptosis DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 11.93 11.37 -0.07 0.01 0.03 11.3 Detail
139 ESCA cuproptosis RAD23B RAD23 homolog B, nucleotide excision repair protein 11.48 11.99 0.06 0.01 0.03 11.3 Detail
140 ESCA cuproptosis UQCRC1 ubiquinol-cytochrome c reductase core protein 1 12.14 11.59 -0.07 0.01 0.03 10.96 Detail
141 ESCA cuproptosis FZD8 frizzled class receptor 8 8.68 7.17 -0.28 0.01 0.03 9.93 Detail
142 ESCA cuproptosis TPI1 triosephosphate isomerase 1 11.99 12.61 0.07 0.01 0.03 9.25 Detail
143 ESCA cuproptosis RPS19 ribosomal protein S19 12.1 12.83 0.08 0.01 0.03 8.9 Detail
144 ESCA cuproptosis COPB2 COPI coat complex subunit beta 2 11.67 12.07 0.05 0.01 0.03 8.22 Detail
145 ESCA cuproptosis EIF3I eukaryotic translation initiation factor 3 subunit I 11.11 11.51 0.05 0.01 0.03 8.22 Detail
146 ESCA cuproptosis RB1 RB transcriptional corepressor 1 10.7 11.17 0.06 0.01 0.03 7.53 Detail
147 ESCA cuproptosis COQ7 coenzyme Q7, hydroxylase 8.68 8.17 -0.09 0.01 0.03 7.19 Detail
148 ESCA cuproptosis SURF6 surfeit 6 8.98 9.39 0.07 0.01 0.03 7.19 Detail
149 ESCA cuproptosis GATC glutamyl-tRNA amidotransferase subunit C 5.28 5.68 0.1 0.01 0.03 6.85 Detail
150 ESCA cuproptosis SLC25A19 solute carrier family 25 member 19 7.28 7.86 0.11 0.01 0.03 6.51 Detail
151 ESCA cuproptosis SOD3 superoxide dismutase 3 10.89 9.21 -0.24 0.01 0.03 6.51 Detail
152 ESCA cuproptosis IMP4 IMP U3 small nucleolar ribonucleoprotein 4 8.99 9.38 0.06 0.01 0.03 6.16 Detail
153 ESCA cuproptosis ULK2 unc-51 like autophagy activating kinase 2 9.56 8.64 -0.15 0.01 0.03 6.16 Detail
154 ESCA cuproptosis SPARC secreted protein acidic and cysteine rich 12.37 13.68 0.15 0.01 0.04 5.82 Detail
155 ESCA cuproptosis MRPS5 mitochondrial ribosomal protein S5 9.28 9.76 0.07 0.01 0.04 5.48 Detail
156 ESCA cuproptosis REXO2 RNA exonuclease 2 9.55 9.15 -0.06 0.01 0.04 4.79 Detail
157 ESCA cuproptosis BECN1 beclin 1 10.66 10.37 -0.04 0.01 0.04 4.45 Detail
158 ESCA cuproptosis RHOV ras homolog family member V 5.34 8.59 0.69 0.01 0.04 4.45 Detail
159 ESCA cuproptosis SHMT2 serine hydroxymethyltransferase 2 10.17 10.97 0.11 0.01 0.04 4.45 Detail
160 ESCA cuproptosis COX4I1 cytochrome c oxidase subunit 4I1 12.59 12.14 -0.05 0.01 0.04 3.77 Detail
161 ESCA cuproptosis SERPIND1 serpin family D member 1 4.44 2.9 -0.62 0.01 0.04 3.42 Detail
162 ESCA cuproptosis INTS6 integrator complex subunit 6 10.28 9.92 -0.05 0.01 0.04 2.4 Detail
163 ESCA cuproptosis SSBP1 single stranded DNA binding protein 1 9.37 9.75 0.06 0.01 0.04 1.71 Detail
164 ESCA cuproptosis TADA2A transcriptional adaptor 2A 7.07 7.37 0.06 0.01 0.04 1.71 Detail
165 ESCA cuproptosis MRPS21 mitochondrial ribosomal protein S21 9.1 9.59 0.08 0.01 0.05 1.37 Detail
166 ESCA cuproptosis SYMPK symplekin scaffold protein 10.87 11.14 0.04 0.01 0.05 1.37 Detail
167 ESCA cuproptosis ANKRD9 ankyrin repeat domain 9 9.41 8.93 -0.08 0.02 0.05 1.03 Detail
168 ESCA cuproptosis MRPL44 mitochondrial ribosomal protein L44 8.55 8.9 0.06 0.02 0.05 1.03 Detail
169 ESCA cuproptosis MRPS25 mitochondrial ribosomal protein S25 9.75 9.3 -0.07 0.02 0.05 0.34 Detail
170 ESCA cuproptosis ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) 8.62 9.35 0.12 0.04 0.08 0.0 Detail
171 ESCA cuproptosis APP amyloid beta precursor protein 13.64 13.79 0.02 0.62 0.71 0.0 Detail
172 ESCA cuproptosis ATOX1 antioxidant 1 copper chaperone 8.56 8.87 0.05 0.09 0.17 0.0 Detail
173 ESCA cuproptosis ATP7A ATPase copper transporting alpha 9.6 9.24 -0.06 0.05 0.11 0.0 Detail
174 ESCA cuproptosis ATP7B ATPase copper transporting beta 8.27 8.14 -0.02 0.83 0.89 0.0 Detail
175 ESCA cuproptosis CCDC22 coiled-coil domain containing 22 8.62 8.57 -0.01 0.93 0.96 0.0 Detail
176 ESCA cuproptosis COX19 cytochrome c oxidase assembly factor COX19 8.27 8.71 0.07 0.04 0.09 0.0 Detail
177 ESCA cuproptosis PRND prion like protein doppel 2.39 2.87 0.27 0.2 0.3 0.0 Detail
178 ESCA cuproptosis PRNP prion protein (Kanno blood group) 11.65 11.81 0.02 0.71 0.79 0.0 Detail
179 ESCA cuproptosis SCO1 synthesis of cytochrome C oxidase 1 8.49 8.56 0.01 0.65 0.74 0.0 Detail
180 ESCA cuproptosis SLC31A1 solute carrier family 31 member 1 10.49 10.48 -0.0 0.97 0.98 0.0 Detail
181 ESCA cuproptosis SLC31A2 solute carrier family 31 member 2 7.98 7.83 -0.03 0.59 0.69 0.0 Detail
182 ESCA cuproptosis AOC1 amine oxidase copper containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
183 ESCA cuproptosis AQP1 aquaporin 1 (Colton blood group) 11.95 10.43 -0.2 0.03 0.08 0.0 Detail
184 ESCA cuproptosis AQP2 aquaporin 2 1.26 1.87 0.57 0.79 0.86 0.0 Detail
185 ESCA cuproptosis BACE1 beta-secretase 1 10.44 9.89 -0.08 0.02 0.06 0.0 Detail
186 ESCA cuproptosis CYP1A1 cytochrome P450 family 1 subfamily A member 1 3.48 1.55 -1.17 0.05 0.11 0.0 Detail
187 ESCA cuproptosis HSF1 heat shock transcription factor 1 10.83 11.22 0.05 0.03 0.08 0.0 Detail
188 ESCA cuproptosis MAP1LC3A microtubule associated protein 1 light chain 3 alpha 8.37 7.79 -0.1 0.06 0.12 0.0 Detail
189 ESCA cuproptosis MT1B metallothionein 1B 0.41 0.09 -2.14 0.74 0.82 0.0 Detail
190 ESCA cuproptosis MT1DP metallothionein 1D, pseudogene 2.01 1.34 -0.59 0.06 0.12 0.0 Detail
191 ESCA cuproptosis MT1E metallothionein 1E 10.32 8.69 -0.25 0.02 0.06 0.0 Detail
192 ESCA cuproptosis MT1F metallothionein 1F 7.75 6.62 -0.23 0.19 0.3 0.0 Detail
193 ESCA cuproptosis MT1H metallothionein 1H 5.05 3.52 -0.52 0.17 0.27 0.0 Detail
194 ESCA cuproptosis MT1HL1 metallothionein 1H like 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
195 ESCA cuproptosis MT4 metallothionein 4 0.57 0.07 -3.14 0.45 0.57 0.0 Detail
196 ESCA cuproptosis SNCA synuclein alpha 5.72 5.36 -0.09 0.61 0.71 0.0 Detail
197 ESCA cuproptosis COMMD1 copper metabolism domain containing 1 8.09 7.87 -0.04 0.15 0.25 0.0 Detail
198 ESCA cuproptosis CUTC cutC copper transporter 7.67 7.4 -0.05 0.08 0.16 0.0 Detail
199 ESCA cuproptosis XIAP X-linked inhibitor of apoptosis 10.47 10.76 0.04 0.07 0.14 0.0 Detail
200 ESCA cuproptosis STEAP2 STEAP2 metalloreductase 9.95 9.99 0.0 1.0 1.0 0.0 Detail
201 ESCA cuproptosis STEAP3 STEAP3 metalloreductase 10.4 10.37 -0.0 0.32 0.44 0.0 Detail
202 ESCA cuproptosis STEAP4 STEAP4 metalloreductase 9.53 8.16 -0.22 0.05 0.1 0.0 Detail
203 ESCA cuproptosis SLC11A2 solute carrier family 11 member 2 10.31 10.36 0.01 0.99 0.99 0.0 Detail
204 ESCA cuproptosis COX17 cytochrome c oxidase copper chaperone COX17 8.33 8.38 0.01 0.85 0.91 0.0 Detail
205 ESCA cuproptosis CP ceruloplasmin 7.05 6.29 -0.16 0.52 0.63 0.0 Detail
206 ESCA cuproptosis FKBP4 FKBP prolyl isomerase 4 11.24 11.45 0.03 0.48 0.6 0.0 Detail
207 ESCA cuproptosis HEPH hephaestin 8.92 9.16 0.04 0.67 0.76 0.0 Detail
208 ESCA cuproptosis MMGT1 membrane magnesium transporter 1 10.34 10.2 -0.02 0.37 0.5 0.0 Detail
209 ESCA cuproptosis PARK7 Parkinsonism associated deglycase 10.78 10.89 0.01 0.44 0.56 0.0 Detail
210 ESCA cuproptosis FAS Fas cell surface death receptor 7.74 8.34 0.11 0.05 0.11 0.0 Detail
211 ESCA cuproptosis FASLG Fas ligand 2.71 3.2 0.24 0.31 0.43 0.0 Detail
212 ESCA cuproptosis RIPK3 receptor interacting serine/threonine kinase 3 7.4 7.4 -0.0 0.71 0.8 0.0 Detail
213 ESCA cuproptosis TLR3 toll like receptor 3 7.6 7.26 -0.07 0.52 0.63 0.0 Detail
214 ESCA cuproptosis FDX1 ferredoxin 1 9.33 8.99 -0.05 0.14 0.24 0.0 Detail
215 ESCA cuproptosis LIAS lipoic acid synthetase 7.3 6.86 -0.09 0.02 0.05 0.0 Detail
216 ESCA cuproptosis LIPT1 lipoyltransferase 1 6.43 6.43 -0.0 0.89 0.93 0.0 Detail
217 ESCA cuproptosis DLD dihydrolipoamide dehydrogenase 11.15 10.7 -0.06 0.02 0.06 0.0 Detail
218 ESCA cuproptosis DLAT dihydrolipoamide S-acetyltransferase 10.21 10.02 -0.03 0.13 0.22 0.0 Detail
219 ESCA cuproptosis PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 11.12 10.61 -0.07 0.07 0.14 0.0 Detail
220 ESCA cuproptosis MTF1 metal regulatory transcription factor 1 9.71 9.43 -0.04 0.32 0.45 0.0 Detail
221 ESCA cuproptosis CDKN2A cyclin dependent kinase inhibitor 2A 5.93 7.13 0.27 0.19 0.3 0.0 Detail
222 ESCA cuproptosis GCSH glycine cleavage system protein H 3.22 3.61 0.17 0.18 0.28 0.0 Detail
223 ESCA cuproptosis AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 9.46 9.66 0.03 0.23 0.34 0.0 Detail
224 ESCA cuproptosis ABCB10 ATP binding cassette subfamily B member 10 8.99 9.16 0.03 0.27 0.38 0.0 Detail
225 ESCA cuproptosis ABCB11 ATP binding cassette subfamily B member 11 1.39 1.16 -0.26 0.44 0.56 0.0 Detail
226 ESCA cuproptosis ABCB4 ATP binding cassette subfamily B member 4 3.03 3.46 0.19 0.65 0.74 0.0 Detail
227 ESCA cuproptosis ABCB7 ATP binding cassette subfamily B member 7 9.04 8.8 -0.04 0.04 0.09 0.0 Detail
228 ESCA cuproptosis ABCB8 ATP binding cassette subfamily B member 8 9.28 9.37 0.01 0.47 0.59 0.0 Detail
229 ESCA cuproptosis ACP1 acid phosphatase 1 10.09 10.27 0.02 0.43 0.55 0.0 Detail
230 ESCA cuproptosis ACTR10 actin related protein 10 9.49 9.42 -0.01 0.58 0.68 0.0 Detail
231 ESCA cuproptosis ADGRE5 adhesion G protein-coupled receptor E5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
232 ESCA cuproptosis AFG3L2 AFG3 like matrix AAA peptidase subunit 2 10.44 10.36 -0.01 0.72 0.81 0.0 Detail
233 ESCA cuproptosis ALAS1 5'-aminolevulinate synthase 1 10.25 10.11 -0.02 0.48 0.6 0.0 Detail
234 ESCA cuproptosis ALB albumin 3.97 1.79 -1.15 0.1 0.18 0.0 Detail
235 ESCA cuproptosis ANKRD49 ankyrin repeat domain 49 8.37 8.51 0.02 0.51 0.63 0.0 Detail
236 ESCA cuproptosis AOC2 amine oxidase copper containing 2 3.82 4.23 0.14 0.48 0.6 0.0 Detail
237 ESCA cuproptosis API5 apoptosis inhibitor 5 11.28 11.41 0.02 0.4 0.53 0.0 Detail
238 ESCA cuproptosis ARFGEF1-DT ARFGEF1 divergent transcript 0.0 0.0 0.0 0.0 0.0 0.0 Detail
239 ESCA cuproptosis ARHGEF39 Rho guanine nucleotide exchange factor 39 0.0 0.0 0.0 0.0 0.0 0.0 Detail
240 ESCA cuproptosis ARMH3 armadillo like helical domain containing 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
241 ESCA cuproptosis ATL2 atlastin GTPase 2 10.76 10.76 -0.0 0.91 0.94 0.0 Detail
242 ESCA cuproptosis ATM ATM serine/threonine kinase 10.41 10.07 -0.05 0.08 0.15 0.0 Detail
243 ESCA cuproptosis ATP5PD ATP synthase peripheral stalk subunit d 0.0 0.0 0.0 0.0 0.0 0.0 Detail
244 ESCA cuproptosis ATP6AP1 ATPase H+ transporting accessory protein 1 11.3 11.55 0.03 0.15 0.26 0.0 Detail
245 ESCA cuproptosis ATP7BP1 ATPase copper transporting beta pseudogene 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
246 ESCA cuproptosis ATP8B1 ATPase phospholipid transporting 8B1 11.93 11.16 -0.1 0.08 0.16 0.0 Detail
247 ESCA cuproptosis ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 8.21 7.88 -0.06 0.05 0.1 0.0 Detail
248 ESCA cuproptosis BARX1 BARX homeobox 1 6.51 4.52 -0.53 0.11 0.19 0.0 Detail
249 ESCA cuproptosis BCKDH protein phosphatase, Mg2+/Mn2+ dependent 1K 0.0 0.0 0.0 0.0 0.0 0.0 Detail
250 ESCA cuproptosis BRPF1 bromodomain and PHD finger containing 1 9.22 9.16 -0.01 0.67 0.76 0.0 Detail
251 ESCA cuproptosis C6orf136 chromosome 6 open reading frame 136 8.01 8.28 0.05 0.45 0.58 0.0 Detail
252 ESCA cuproptosis C6ORF136 chromosome 6 open reading frame 136 0.0 0.0 0.0 0.0 0.0 0.0 Detail
253 ESCA cuproptosis C7orf26 integrator complex subunit 15 9.21 9.42 0.03 0.05 0.11 0.0 Detail
254 ESCA cuproptosis CCDC115 coiled-coil domain containing 115 8.9 8.91 0.0 0.89 0.93 0.0 Detail
255 ESCA cuproptosis CCL5 C-C motif chemokine ligand 5 7.47 8.06 0.11 0.33 0.45 0.0 Detail
256 ESCA cuproptosis CCL8 C-C motif chemokine ligand 8 3.3 4.17 0.34 0.23 0.34 0.0 Detail
257 ESCA cuproptosis CCS copper chaperone for superoxide dismutase 8.34 8.33 -0.0 0.73 0.81 0.0 Detail
258 ESCA cuproptosis CD274 CD274 molecule 4.54 5.3 0.22 0.04 0.09 0.0 Detail
259 ESCA cuproptosis CDC16 cell division cycle 16 10.3 10.22 -0.01 0.56 0.67 0.0 Detail
260 ESCA cuproptosis CEPT1 choline/ethanolamine phosphotransferase 1 8.99 8.97 -0.0 0.8 0.87 0.0 Detail
261 ESCA cuproptosis CERS2 ceramide synthase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
262 ESCA cuproptosis CERT1 ceramide transporter 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
263 ESCA cuproptosis CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 8.48 8.85 0.06 0.02 0.06 0.0 Detail
264 ESCA cuproptosis CHTOP chromatin target of PRMT1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
265 ESCA cuproptosis CIAO1 cytosolic iron-sulfur assembly component 1 10.43 10.6 0.02 0.13 0.23 0.0 Detail
266 ESCA cuproptosis CIAO2A cytosolic iron-sulfur assembly component 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
267 ESCA cuproptosis CIAO2B cytosolic iron-sulfur assembly component 2B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
268 ESCA cuproptosis CIAPIN1 cytokine induced apoptosis inhibitor 1 9.24 9.58 0.05 0.08 0.16 0.0 Detail
269 ESCA cuproptosis CISD1 CDGSH iron sulfur domain 1 8.71 8.62 -0.01 0.56 0.67 0.0 Detail
270 ESCA cuproptosis CIT citron rho-interacting serine/threonine kinase 9.27 9.96 0.1 0.04 0.09 0.0 Detail
271 ESCA cuproptosis CLEC11A C-type lectin domain containing 11A 6.78 7.26 0.1 0.18 0.29 0.0 Detail
272 ESCA cuproptosis CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 9.15 9.31 0.02 0.36 0.48 0.0 Detail
273 ESCA cuproptosis CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X 9.71 9.67 -0.01 0.65 0.74 0.0 Detail
274 ESCA cuproptosis CLUH clustered mitochondria homolog 0.0 0.0 0.0 0.0 0.0 0.0 Detail
275 ESCA cuproptosis CMC1 C-X9-C motif containing 1 6.97 7.03 0.01 0.83 0.89 0.0 Detail
276 ESCA cuproptosis CMPK1 cytidine/uridine monophosphate kinase 1 12.01 12.09 0.01 0.92 0.95 0.0 Detail
277 ESCA cuproptosis COA5 cytochrome c oxidase assembly factor 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
278 ESCA cuproptosis COA6 cytochrome c oxidase assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
279 ESCA cuproptosis COAS unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
280 ESCA cuproptosis copper鈥搝inc alloy (CZA) unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
281 ESCA cuproptosis COPZ1 COPI coat complex subunit zeta 1 11.04 11.43 0.05 0.05 0.1 0.0 Detail
282 ESCA cuproptosis COX11 cytochrome c oxidase copper chaperone COX11 9.71 9.59 -0.02 0.21 0.31 0.0 Detail
283 ESCA cuproptosis COX14 cytochrome c oxidase assembly factor COX14 0.0 0.0 0.0 0.0 0.0 0.0 Detail
284 ESCA cuproptosis COX15 cytochrome c oxidase assembly homolog COX15 10.14 10.1 -0.01 0.8 0.87 0.0 Detail
285 ESCA cuproptosis COX18 cytochrome c oxidase assembly factor COX18 8.07 7.92 -0.03 0.56 0.67 0.0 Detail
286 ESCA cuproptosis COX23 coiled-coil-helix-coiled-coil-helix domain containing 7 0.0 0.0 0.0 0.0 0.0 0.0 Detail
287 ESCA cuproptosis COX6B1 cytochrome c oxidase subunit 6B1 11.27 11.28 0.0 0.77 0.84 0.0 Detail
288 ESCA cuproptosis COX7A1 cytochrome c oxidase subunit 7A1 6.88 5.45 -0.34 0.02 0.05 0.0 Detail
289 ESCA cuproptosis COX7B cytochrome c oxidase subunit 7B 11.06 10.84 -0.03 0.17 0.27 0.0 Detail
290 ESCA cuproptosis CS citrate synthase 12.41 12.2 -0.02 0.13 0.23 0.0 Detail
291 ESCA cuproptosis CTR1 solute carrier family 31 member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
292 ESCA cuproptosis CTR2 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
293 ESCA cuproptosis CYC1 cytochrome c1 11.0 11.24 0.03 0.25 0.36 0.0 Detail
294 ESCA cuproptosis CYCS cytochrome c, somatic 11.73 12.05 0.04 0.19 0.29 0.0 Detail
295 ESCA cuproptosis DAPK2 death associated protein kinase 2 7.16 7.03 -0.03 0.74 0.82 0.0 Detail
296 ESCA cuproptosis DARS1 aspartyl-tRNA synthetase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
297 ESCA cuproptosis DBH dopamine beta-hydroxylase 3.36 2.12 -0.66 0.03 0.07 0.0 Detail
298 ESCA cuproptosis DCYTB cytochrome b reductase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
299 ESCA cuproptosis DDX20 DEAD-box helicase 20 8.42 8.71 0.05 0.02 0.06 0.0 Detail
300 ESCA cuproptosis DHX15 DEAH-box helicase 15 11.36 11.61 0.03 0.03 0.07 0.0 Detail
301 ESCA cuproptosis DLG3 discs large MAGUK scaffold protein 3 10.06 9.74 -0.05 0.2 0.3 0.0 Detail
302 ESCA cuproptosis DLST dihydrolipoamide S-succinyltransferase 10.88 10.63 -0.03 0.04 0.09 0.0 Detail
303 ESCA cuproptosis DMT1 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
304 ESCA cuproptosis DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 9.99 10.15 0.02 0.42 0.55 0.0 Detail
305 ESCA cuproptosis DNM1L dynamin 1 like 10.85 11.05 0.03 0.22 0.32 0.0 Detail
306 ESCA cuproptosis DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 10.17 10.33 0.02 0.18 0.28 0.0 Detail
307 ESCA cuproptosis DOT1L DOT1 like histone lysine methyltransferase 10.93 10.97 0.01 0.62 0.71 0.0 Detail
308 ESCA cuproptosis DPH1 diphthamide biosynthesis 1 9.26 9.07 -0.03 0.17 0.27 0.0 Detail
309 ESCA cuproptosis DPYD dihydropyrimidine dehydrogenase 9.18 8.79 -0.06 0.5 0.62 0.0 Detail
310 ESCA cuproptosis DYNLRB1 dynein light chain roadblock-type 1 10.73 11.14 0.05 0.02 0.05 0.0 Detail
311 ESCA cuproptosis EARS2 glutamyl-tRNA synthetase 2, mitochondrial 8.85 9.01 0.03 0.28 0.39 0.0 Detail
312 ESCA cuproptosis EFCC1 EF-hand and coiled-coil domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
313 ESCA cuproptosis EGFR epidermal growth factor receptor 11.66 11.74 0.01 0.88 0.93 0.0 Detail
314 ESCA cuproptosis EGLN1 egl-9 family hypoxia inducible factor 1 10.95 10.56 -0.05 0.03 0.07 0.0 Detail
315 ESCA cuproptosis EIF4G1 eukaryotic translation initiation factor 4 gamma 1 13.38 13.68 0.03 0.14 0.24 0.0 Detail
316 ESCA cuproptosis ELF3 E74 like ETS transcription factor 3 9.96 11.96 0.26 0.03 0.08 0.0 Detail
317 ESCA cuproptosis ELOB elongin B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
318 ESCA cuproptosis ELP3 elongator acetyltransferase complex subunit 3 8.75 8.74 -0.0 0.9 0.93 0.0 Detail
319 ESCA cuproptosis EMC6 ER membrane protein complex subunit 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
320 ESCA cuproptosis ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 7.48 6.88 -0.12 0.55 0.66 0.0 Detail
321 ESCA cuproptosis EPC2 enhancer of polycomb homolog 2 9.12 9.06 -0.01 0.98 0.99 0.0 Detail
322 ESCA cuproptosis ERK1 mitogen-activated protein kinase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
323 ESCA cuproptosis EXOC3 exocyst complex component 3 10.55 10.29 -0.04 0.11 0.2 0.0 Detail
324 ESCA cuproptosis FAK protein tyrosine kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
325 ESCA cuproptosis FAM111A FAM111 trypsin like peptidase A 9.24 9.88 0.1 0.05 0.11 0.0 Detail
326 ESCA cuproptosis FAM96A cytosolic iron-sulfur assembly component 2A 8.59 9.3 0.12 0.06 0.13 0.0 Detail
327 ESCA cuproptosis FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 7.86 7.6 -0.05 0.2 0.31 0.0 Detail
328 ESCA cuproptosis FASTKD5 FAST kinase domains 5 8.62 8.89 0.04 0.12 0.21 0.0 Detail
329 ESCA cuproptosis FAU FAU ubiquitin like and ribosomal protein S30 fusion 11.35 11.41 0.01 0.83 0.89 0.0 Detail
330 ESCA cuproptosis FDX2 ferredoxin 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
331 ESCA cuproptosis FDXR ferredoxin reductase 7.57 8.21 0.12 0.1 0.19 0.0 Detail
332 ESCA cuproptosis FOXD2-AS1 FOXD2 adjacent opposite strand RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
333 ESCA cuproptosis FXN frataxin 7.97 7.86 -0.02 0.42 0.55 0.0 Detail
334 ESCA cuproptosis GADD45GIP1 GADD45G interacting protein 1 9.13 9.52 0.06 0.06 0.13 0.0 Detail
335 ESCA cuproptosis GATB glutamyl-tRNA amidotransferase subunit B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
336 ESCA cuproptosis GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 11.85 11.73 -0.01 0.2 0.31 0.0 Detail
337 ESCA cuproptosis GCLC glutamate-cysteine ligase catalytic subunit 10.5 10.72 0.03 0.72 0.81 0.0 Detail
338 ESCA cuproptosis GCLM glutamate-cysteine ligase modifier subunit 8.68 9.51 0.13 0.02 0.06 0.0 Detail
339 ESCA cuproptosis GFM1 G elongation factor mitochondrial 1 10.21 10.62 0.06 0.02 0.06 0.0 Detail
340 ESCA cuproptosis GGPS1 geranylgeranyl diphosphate synthase 1 9.33 9.41 0.01 0.55 0.66 0.0 Detail
341 ESCA cuproptosis GLRX5 glutaredoxin 5 9.44 9.56 0.02 0.39 0.52 0.0 Detail
342 ESCA cuproptosis GLS40 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
343 ESCA cuproptosis glycerophospholipid unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
344 ESCA cuproptosis GNL3 G protein nucleolar 3 10.08 10.37 0.04 0.25 0.36 0.0 Detail
345 ESCA cuproptosis GPX4 glutathione peroxidase 4 10.92 11.19 0.03 0.13 0.22 0.0 Detail
346 ESCA cuproptosis GRX1 glutaredoxin 0.0 0.0 0.0 0.0 0.0 0.0 Detail
347 ESCA cuproptosis GSH unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
348 ESCA cuproptosis GTF2B general transcription factor IIB 8.79 8.87 0.01 0.43 0.55 0.0 Detail
349 ESCA cuproptosis GTPBP6 GTP binding protein 6 (putative) 0.0 0.0 0.0 0.0 0.0 0.0 Detail
350 ESCA cuproptosis H1-10-AS1 H1-10 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
351 ESCA cuproptosis H2AC6 H2A clustered histone 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
352 ESCA cuproptosis H2BC6-AS1 H2BC6 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
353 ESCA cuproptosis H3C1 H3 clustered histone 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
354 ESCA cuproptosis HARS2 histidyl-tRNA synthetase 2, mitochondrial 8.95 8.92 -0.0 0.92 0.95 0.0 Detail
355 ESCA cuproptosis HCCS holocytochrome c synthase 8.92 9.08 0.03 0.18 0.28 0.0 Detail
356 ESCA cuproptosis HIST1H3A H3 clustered histone 1 0.33 0.96 1.53 0.02 0.05 0.0 Detail
357 ESCA cuproptosis HSCB HscB mitochondrial iron-sulfur cluster cochaperone 7.12 6.94 -0.04 0.18 0.28 0.0 Detail
358 ESCA cuproptosis HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 9.38 9.82 0.07 0.02 0.05 0.0 Detail
359 ESCA cuproptosis HSP70 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
360 ESCA cuproptosis HSPA8 heat shock protein family A (Hsp70) member 8 14.77 14.46 -0.03 0.14 0.23 0.0 Detail
361 ESCA cuproptosis HSPA9 heat shock protein family A (Hsp70) member 9 11.98 12.19 0.02 0.13 0.23 0.0 Detail
362 ESCA cuproptosis HSPH1 heat shock protein family H (Hsp110) member 1 11.32 12.02 0.09 0.02 0.06 0.0 Detail
363 ESCA cuproptosis IBA57 iron-sulfur cluster assembly factor IBA57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
364 ESCA cuproptosis IDH1 isocitrate dehydrogenase (NADP(+)) 1 10.53 11.28 0.1 0.06 0.13 0.0 Detail
365 ESCA cuproptosis IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha 10.22 10.48 0.04 0.11 0.19 0.0 Detail
366 ESCA cuproptosis IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta 10.12 10.25 0.02 0.36 0.48 0.0 Detail
367 ESCA cuproptosis IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma 9.99 10.23 0.03 0.12 0.21 0.0 Detail
368 ESCA cuproptosis IFT81 intraflagellar transport 81 7.32 7.75 0.08 0.16 0.26 0.0 Detail
369 ESCA cuproptosis IL-8 C-X-C motif chemokine ligand 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
370 ESCA cuproptosis INKA1 inka box actin regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
371 ESCA cuproptosis INSL4 insulin like 4 0.07 0.59 3.06 0.09 0.17 0.0 Detail
372 ESCA cuproptosis IOP1 cytosolic iron-sulfur assembly component 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
373 ESCA cuproptosis ISCA1 iron-sulfur cluster assembly 1 9.32 9.02 -0.05 0.04 0.08 0.0 Detail
374 ESCA cuproptosis ISCA2 iron-sulfur cluster assembly 2 7.41 7.76 0.07 0.14 0.24 0.0 Detail
375 ESCA cuproptosis ISCU2 iron-sulfur cluster assembly enzyme 0.0 0.0 0.0 0.0 0.0 0.0 Detail
376 ESCA cuproptosis ISD11 LYR motif containing 4 0.0 0.0 0.0 0.0 0.0 0.0 Detail
377 ESCA cuproptosis KAT8 lysine acetyltransferase 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
378 ESCA cuproptosis KIDINS220 kinase D interacting substrate 220 11.31 11.07 -0.03 0.1 0.19 0.0 Detail
379 ESCA cuproptosis KLF5 KLF transcription factor 5 11.37 12.93 0.19 0.02 0.06 0.0 Detail
380 ESCA cuproptosis KMT2A lysine methyltransferase 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
381 ESCA cuproptosis LARS2 leucyl-tRNA synthetase 2, mitochondrial 9.03 8.95 -0.01 0.5 0.62 0.0 Detail
382 ESCA cuproptosis LASTR lncRNA associated with SART3 regulation of splicing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
383 ESCA cuproptosis LDLR low density lipoprotein receptor 11.85 11.94 0.01 0.9 0.93 0.0 Detail
384 ESCA cuproptosis LINC02038 long intergenic non-protein coding RNA 2038 0.0 0.0 0.0 0.0 0.0 0.0 Detail
385 ESCA cuproptosis LINC02154 long intergenic non-protein coding RNA 2154 0.0 0.0 0.0 0.0 0.0 0.0 Detail
386 ESCA cuproptosis LINC03085 long intergenic non-protein coding RNA 3085 0.0 0.0 0.0 0.0 0.0 0.0 Detail
387 ESCA cuproptosis LIPT2 lipoyl(octanoyl) transferase 2 4.87 5.6 0.2 0.03 0.08 0.0 Detail
388 ESCA cuproptosis LONP1 lon peptidase 1, mitochondrial 10.59 10.62 0.0 0.84 0.89 0.0 Detail
389 ESCA cuproptosis LOX lysyl oxidase 8.69 9.59 0.14 0.07 0.13 0.0 Detail
390 ESCA cuproptosis MADD MAP kinase activating death domain 10.54 10.3 -0.03 0.11 0.2 0.0 Detail
391 ESCA cuproptosis MAL2 mal, T cell differentiation protein 2 11.03 12.69 0.2 0.16 0.26 0.0 Detail
392 ESCA cuproptosis MAP2K2 mitogen-activated protein kinase kinase 2 10.87 10.96 0.01 0.41 0.54 0.0 Detail
393 ESCA cuproptosis MARCHF5 membrane associated ring-CH-type finger 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
394 ESCA cuproptosis MARS2 methionyl-tRNA synthetase 2, mitochondrial 8.03 8.23 0.04 0.39 0.52 0.0 Detail
395 ESCA cuproptosis MAU2 MAU2 sister chromatid cohesion factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
396 ESCA cuproptosis MBTPS1 membrane bound transcription factor peptidase, site 1 11.58 11.3 -0.04 0.05 0.11 0.0 Detail
397 ESCA cuproptosis MBTPS2 membrane bound transcription factor peptidase, site 2 9.22 9.27 0.01 0.98 0.98 0.0 Detail
398 ESCA cuproptosis MCAT malonyl-CoA-acyl carrier protein transacylase 7.84 8.04 0.04 0.29 0.41 0.0 Detail
399 ESCA cuproptosis MCMBP minichromosome maintenance complex binding protein 0.0 0.0 0.0 0.0 0.0 0.0 Detail
400 ESCA cuproptosis MCUR1 mitochondrial calcium uniporter regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
401 ESCA cuproptosis MDH2 malate dehydrogenase 2 11.84 12.12 0.03 0.13 0.22 0.0 Detail
402 ESCA cuproptosis MECR mitochondrial trans-2-enoyl-CoA reductase 8.06 7.91 -0.03 0.23 0.34 0.0 Detail
403 ESCA cuproptosis MEK1 mitogen-activated protein kinase kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
404 ESCA cuproptosis MEK2 mitogen-activated protein kinase kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
405 ESCA cuproptosis METTL17 methyltransferase like 17 0.0 0.0 0.0 0.0 0.0 0.0 Detail
406 ESCA cuproptosis MFF mitochondrial fission factor 9.77 9.83 0.01 0.69 0.78 0.0 Detail
407 ESCA cuproptosis MFN2 mitofusin 2 11.95 11.49 -0.06 0.03 0.08 0.0 Detail
408 ESCA cuproptosis MOXD1 monooxygenase DBH like 1 8.42 7.61 -0.15 0.22 0.33 0.0 Detail
409 ESCA cuproptosis MPC1 mitochondrial pyruvate carrier 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
410 ESCA cuproptosis MPI mannose phosphate isomerase 9.04 8.96 -0.01 0.62 0.71 0.0 Detail
411 ESCA cuproptosis MPZL3 myelin protein zero like 3 5.53 6.21 0.17 0.32 0.45 0.0 Detail
412 ESCA cuproptosis MRM2 mitochondrial rRNA methyltransferase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
413 ESCA cuproptosis MRPL15 mitochondrial ribosomal protein L15 9.22 9.64 0.06 0.03 0.08 0.0 Detail
414 ESCA cuproptosis MRPL16 mitochondrial ribosomal protein L16 9.09 9.11 0.0 0.97 0.98 0.0 Detail
415 ESCA cuproptosis MRPL30 mitochondrial ribosomal protein L30 9.61 9.89 0.04 0.04 0.1 0.0 Detail
416 ESCA cuproptosis MRPL34 mitochondrial ribosomal protein L34 9.43 9.08 -0.06 0.03 0.08 0.0 Detail
417 ESCA cuproptosis MRPL39 mitochondrial ribosomal protein L39 8.19 7.9 -0.05 0.07 0.13 0.0 Detail
418 ESCA cuproptosis MRPL40 mitochondrial ribosomal protein L40 8.64 8.71 0.01 0.63 0.72 0.0 Detail
419 ESCA cuproptosis MRPL41 mitochondrial ribosomal protein L41 9.02 8.99 -0.0 0.65 0.74 0.0 Detail
420 ESCA cuproptosis MRPL52 mitochondrial ribosomal protein L52 8.38 8.8 0.07 0.04 0.09 0.0 Detail
421 ESCA cuproptosis MRPL53 mitochondrial ribosomal protein L53 8.58 8.63 0.01 0.95 0.97 0.0 Detail
422 ESCA cuproptosis MRPL55 mitochondrial ribosomal protein L55 8.32 8.63 0.05 0.04 0.09 0.0 Detail
423 ESCA cuproptosis MRPL57 mitochondrial ribosomal protein L57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
424 ESCA cuproptosis MRPS11 mitochondrial ribosomal protein S11 8.64 8.95 0.05 0.03 0.08 0.0 Detail
425 ESCA cuproptosis MRPS14 mitochondrial ribosomal protein S14 8.18 8.28 0.02 0.35 0.47 0.0 Detail
426 ESCA cuproptosis MRPS16 mitochondrial ribosomal protein S16 10.03 10.32 0.04 0.05 0.1 0.0 Detail
427 ESCA cuproptosis MRPS18A mitochondrial ribosomal protein S18A 9.14 9.31 0.03 0.76 0.84 0.0 Detail
428 ESCA cuproptosis MRPS18B mitochondrial ribosomal protein S18B 9.87 10.07 0.03 0.38 0.51 0.0 Detail
429 ESCA cuproptosis MRPS18C mitochondrial ribosomal protein S18C 7.99 7.85 -0.03 0.33 0.45 0.0 Detail
430 ESCA cuproptosis MRPS22 mitochondrial ribosomal protein S22 8.73 9.17 0.07 0.02 0.05 0.0 Detail
431 ESCA cuproptosis MRPS23 mitochondrial ribosomal protein S23 8.81 8.97 0.02 0.42 0.55 0.0 Detail
432 ESCA cuproptosis MRPS2 mitochondrial ribosomal protein S2 9.37 9.84 0.07 0.02 0.05 0.0 Detail
433 ESCA cuproptosis MRPS33 mitochondrial ribosomal protein S33 8.17 8.35 0.03 0.42 0.55 0.0 Detail
434 ESCA cuproptosis MRPS7 mitochondrial ribosomal protein S7 9.56 9.67 0.02 0.54 0.65 0.0 Detail
435 ESCA cuproptosis MRPS9 mitochondrial ribosomal protein S9 8.82 8.9 0.01 0.69 0.78 0.0 Detail
436 ESCA cuproptosis MT1 metallothionein 1A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
437 ESCA cuproptosis MT2 metallothionein 1B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
438 ESCA cuproptosis MT3A unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
439 ESCA cuproptosis MT-CO1 mitochondrially encoded cytochrome c oxidase I 0.0 0.0 0.0 0.0 0.0 0.0 Detail
440 ESCA cuproptosis MT-CO2 mitochondrially encoded cytochrome c oxidase II 0.0 0.0 0.0 0.0 0.0 0.0 Detail
441 ESCA cuproptosis MTCO2P12 MT-CO2 pseudogene 12 0.0 0.0 0.0 0.0 0.0 0.0 Detail
442 ESCA cuproptosis MT-CO3 mitochondrially encoded cytochrome c oxidase III 0.0 0.0 0.0 0.0 0.0 0.0 Detail
443 ESCA cuproptosis MT unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
444 ESCA cuproptosis MTERF1 mitochondrial transcription termination factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
445 ESCA cuproptosis MTFR1 mitochondrial fission regulator 1 9.34 9.59 0.04 0.24 0.35 0.0 Detail
446 ESCA cuproptosis MTFR1L mitochondrial fission regulator 1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
447 ESCA cuproptosis MTG1 mitochondrial ribosome associated GTPase 1 8.29 8.55 0.04 0.61 0.71 0.0 Detail
448 ESCA cuproptosis MTIF3 mitochondrial translational initiation factor 3 9.53 9.18 -0.05 0.08 0.15 0.0 Detail
449 ESCA cuproptosis MTO1 mitochondrial tRNA translation optimization 1 8.86 8.66 -0.03 0.08 0.16 0.0 Detail
450 ESCA cuproptosis mTOR mechanistic target of rapamycin kinase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
451 ESCA cuproptosis MUC20 mucin 20, cell surface associated 8.26 9.11 0.14 0.17 0.27 0.0 Detail
452 ESCA cuproptosis NAPA NSF attachment protein alpha 11.56 11.36 -0.02 0.51 0.63 0.0 Detail
453 ESCA cuproptosis NARS2 asparaginyl-tRNA synthetase 2, mitochondrial 7.97 8.3 0.06 0.16 0.26 0.0 Detail
454 ESCA cuproptosis NDOR1 NADPH dependent diflavin oxidoreductase 1 10.16 9.99 -0.02 0.15 0.25 0.0 Detail
455 ESCA cuproptosis NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 9.88 9.74 -0.02 0.26 0.37 0.0 Detail
456 ESCA cuproptosis NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 10.06 10.04 -0.0 0.86 0.91 0.0 Detail
457 ESCA cuproptosis NDUFA4 NDUFA4 mitochondrial complex associated 11.16 10.93 -0.03 0.17 0.28 0.0 Detail
458 ESCA cuproptosis NDUFA6 NADH:ubiquinone oxidoreductase subunit A6 10.08 9.84 -0.03 0.08 0.16 0.0 Detail
459 ESCA cuproptosis NDUFA8 NADH:ubiquinone oxidoreductase subunit A8 9.34 9.04 -0.05 0.04 0.09 0.0 Detail
460 ESCA cuproptosis NDUFA9 NADH:ubiquinone oxidoreductase subunit A9 9.95 10.11 0.02 0.45 0.58 0.0 Detail
461 ESCA cuproptosis NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 9.91 9.97 0.01 0.85 0.91 0.0 Detail
462 ESCA cuproptosis NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
463 ESCA cuproptosis NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 10.14 9.86 -0.04 0.1 0.18 0.0 Detail
464 ESCA cuproptosis NDUFB11 NADH:ubiquinone oxidoreductase subunit B11 10.11 10.09 -0.0 0.83 0.89 0.0 Detail
465 ESCA cuproptosis NDUFB2 NADH:ubiquinone oxidoreductase subunit B2 9.72 9.34 -0.06 0.02 0.06 0.0 Detail
466 ESCA cuproptosis NDUFB4 NADH:ubiquinone oxidoreductase subunit B4 10.51 10.73 0.03 0.25 0.37 0.0 Detail
467 ESCA cuproptosis NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 10.35 10.42 0.01 0.89 0.93 0.0 Detail
468 ESCA cuproptosis NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 9.12 8.99 -0.02 0.28 0.39 0.0 Detail
469 ESCA cuproptosis NDUFB7 NADH:ubiquinone oxidoreductase subunit B7 9.97 9.72 -0.04 0.09 0.16 0.0 Detail
470 ESCA cuproptosis NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 10.84 11.1 0.03 0.26 0.37 0.0 Detail
471 ESCA cuproptosis NDUFC1 NADH:ubiquinone oxidoreductase subunit C1 9.05 8.87 -0.03 0.29 0.41 0.0 Detail
472 ESCA cuproptosis NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 10.28 10.52 0.03 0.16 0.26 0.0 Detail
473 ESCA cuproptosis NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 10.77 10.61 -0.02 0.36 0.48 0.0 Detail
474 ESCA cuproptosis NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 9.93 9.88 -0.01 0.47 0.59 0.0 Detail
475 ESCA cuproptosis NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 11.01 10.75 -0.04 0.08 0.16 0.0 Detail
476 ESCA cuproptosis NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 9.91 9.74 -0.02 0.29 0.41 0.0 Detail
477 ESCA cuproptosis NFKBIA NFKB inhibitor alpha 11.06 11.3 0.03 0.47 0.59 0.0 Detail
478 ESCA cuproptosis NFS1 NFS1 cysteine desulfurase 8.87 9.13 0.04 0.21 0.31 0.0 Detail
479 ESCA cuproptosis NFU1 NFU1 iron-sulfur cluster scaffold 8.41 8.24 -0.03 0.24 0.35 0.0 Detail
480 ESCA cuproptosis NFYC nuclear transcription factor Y subunit gamma 9.8 9.96 0.02 0.43 0.56 0.0 Detail
481 ESCA cuproptosis NLRP3 NLR family pyrin domain containing 3 5.17 4.94 -0.06 0.59 0.69 0.0 Detail
482 ESCA cuproptosis NNAT neuronatin 5.39 5.18 -0.06 0.28 0.4 0.0 Detail
483 ESCA cuproptosis NPL4 NPL4 homolog, ubiquitin recognition factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
484 ESCA cuproptosis NRF1 nuclear respiratory factor 1 8.01 8.17 0.03 0.02 0.05 0.0 Detail
485 ESCA cuproptosis NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase 10.36 10.55 0.03 0.27 0.38 0.0 Detail
486 ESCA cuproptosis NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic 8.49 8.41 -0.01 0.58 0.69 0.0 Detail
487 ESCA cuproptosis NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic 9.01 9.14 0.02 0.39 0.52 0.0 Detail
488 ESCA cuproptosis NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial 7.99 8.03 0.01 0.8 0.87 0.0 Detail
489 ESCA cuproptosis OGDHL oxoglutarate dehydrogenase L 4.05 4.14 0.03 0.94 0.97 0.0 Detail
490 ESCA cuproptosis OSBPL9 oxysterol binding protein like 9 10.76 10.47 -0.04 0.2 0.31 0.0 Detail
491 ESCA cuproptosis OXA1L OXA1L mitochondrial inner membrane protein 11.04 10.98 -0.01 0.57 0.68 0.0 Detail
492 ESCA cuproptosis P3H3 prolyl 3-hydroxylase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
493 ESCA cuproptosis p53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
494 ESCA cuproptosis P53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
495 ESCA cuproptosis p97 eukaryotic translation initiation factor 4 gamma 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
496 ESCA cuproptosis PARS2 prolyl-tRNA synthetase 2, mitochondrial 7.01 7.09 0.02 0.77 0.84 0.0 Detail
497 ESCA cuproptosis PCBP2 poly(rC) binding protein 2 12.8 12.67 -0.01 0.55 0.66 0.0 Detail
498 ESCA cuproptosis PCGF6 polycomb group ring finger 6 6.96 7.39 0.09 0.02 0.06 0.0 Detail
499 ESCA cuproptosis PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.18 10.12 -0.01 0.59 0.69 0.0 Detail
500 ESCA cuproptosis PDE3B phosphodiesterase 3B 8.46 8.1 -0.06 0.67 0.76 0.0 Detail
501 ESCA cuproptosis PDHA pyruvate dehydrogenase E1 subunit alpha 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
502 ESCA cuproptosis PDH pyruvate dehydrogenase phosphatase catalytic subunit 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
503 ESCA cuproptosis PDHX pyruvate dehydrogenase complex component X 9.73 9.35 -0.06 0.06 0.13 0.0 Detail
504 ESCA cuproptosis PDK1 pyruvate dehydrogenase kinase 1 9.77 9.39 -0.06 0.02 0.06 0.0 Detail
505 ESCA cuproptosis PET100 PET100 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
506 ESCA cuproptosis PET117 PET117 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
507 ESCA cuproptosis PFKP phosphofructokinase, platelet 10.47 11.45 0.13 0.02 0.06 0.0 Detail
508 ESCA cuproptosis PGP phosphoglycolate phosphatase 8.4 8.79 0.07 0.04 0.1 0.0 Detail
509 ESCA cuproptosis PHOB unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
510 ESCA cuproptosis PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.0 0.0 0.0 0.0 0.0 0.0 Detail
511 ESCA cuproptosis PITRM1 pitrilysin metallopeptidase 1 10.92 10.94 0.0 0.93 0.96 0.0 Detail
512 ESCA cuproptosis PMVK phosphomevalonate kinase 9.67 9.2 -0.07 0.02 0.06 0.0 Detail
513 ESCA cuproptosis POLG DNA polymerase gamma, catalytic subunit 10.36 10.43 0.01 0.54 0.65 0.0 Detail
514 ESCA cuproptosis POLR2B RNA polymerase II subunit B 11.06 11.19 0.02 0.54 0.65 0.0 Detail
515 ESCA cuproptosis POT1 protection of telomeres 1 8.69 8.89 0.03 0.3 0.42 0.0 Detail
516 ESCA cuproptosis PPA2 inorganic pyrophosphatase 2 9.92 9.66 -0.04 0.08 0.15 0.0 Detail
517 ESCA cuproptosis PPIE peptidylprolyl isomerase E 8.94 9.09 0.02 0.59 0.69 0.0 Detail
518 ESCA cuproptosis PPP1R15A protein phosphatase 1 regulatory subunit 15A 10.72 10.83 0.01 0.76 0.84 0.0 Detail
519 ESCA cuproptosis PRDM10 PR/SET domain 10 8.65 8.73 0.01 0.38 0.51 0.0 Detail
520 ESCA cuproptosis PSMD6 proteasome 26S subunit, non-ATPase 6 9.8 9.75 -0.01 0.89 0.93 0.0 Detail
521 ESCA cuproptosis PTCD3 pentatricopeptide repeat domain 3 9.98 10.23 0.04 0.05 0.11 0.0 Detail
522 ESCA cuproptosis PTPMT1 protein tyrosine phosphatase mitochondrial 1 8.98 9.13 0.02 0.34 0.46 0.0 Detail
523 ESCA cuproptosis PURG purine rich element binding protein G 2.59 1.85 -0.49 0.07 0.14 0.0 Detail
524 ESCA cuproptosis QRSL1 glutaminyl-tRNA amidotransferase subunit QRSL1 8.74 8.78 0.01 0.97 0.98 0.0 Detail
525 ESCA cuproptosis RANTES C-C motif chemokine ligand 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
526 ESCA cuproptosis RCC1L RCC1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
527 ESCA cuproptosis RMND1 required for meiotic nuclear division 1 homolog 7.76 8.05 0.05 0.05 0.11 0.0 Detail
528 ESCA cuproptosis RPAIN RPA interacting protein 8.7 8.73 0.01 0.89 0.93 0.0 Detail
529 ESCA cuproptosis RPAP1 RNA polymerase II associated protein 1 9.63 9.66 0.01 0.72 0.81 0.0 Detail
530 ESCA cuproptosis RPL10A ribosomal protein L10a 12.61 12.48 -0.02 0.95 0.98 0.0 Detail
531 ESCA cuproptosis RPL19 ribosomal protein L19 13.16 13.46 0.03 0.15 0.26 0.0 Detail
532 ESCA cuproptosis RPL27 ribosomal protein L27 12.71 12.84 0.02 0.31 0.43 0.0 Detail
533 ESCA cuproptosis RPL28 ribosomal protein L28 13.47 14.11 0.07 0.02 0.06 0.0 Detail
534 ESCA cuproptosis RPL7A ribosomal protein L7a 12.59 12.51 -0.01 0.99 0.99 0.0 Detail
535 ESCA cuproptosis RPLP0 ribosomal protein lateral stalk subunit P0 13.74 13.84 0.01 0.44 0.57 0.0 Detail
536 ESCA cuproptosis RPS25 ribosomal protein S25 11.86 11.59 -0.03 0.26 0.37 0.0 Detail
537 ESCA cuproptosis RPS27A ribosomal protein S27a 11.61 11.67 0.01 0.62 0.72 0.0 Detail
538 ESCA cuproptosis RPUSD3 RNA pseudouridine synthase D3 8.51 8.73 0.04 0.22 0.33 0.0 Detail
539 ESCA cuproptosis RPUSD4 RNA pseudouridine synthase D4 8.83 8.55 -0.05 0.11 0.2 0.0 Detail
540 ESCA cuproptosis RRN3 RRN3 homolog, RNA polymerase I transcription factor 10.09 10.21 0.02 0.53 0.65 0.0 Detail
541 ESCA cuproptosis RSL1D1 ribosomal L1 domain containing 1 11.38 11.58 0.03 0.19 0.29 0.0 Detail
542 ESCA cuproptosis RTEL1 regulator of telomere elongation helicase 1 9.11 9.63 0.08 0.04 0.08 0.0 Detail
543 ESCA cuproptosis S6K1 ribosomal protein S6 kinase B1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
544 ESCA cuproptosis SAMM50 SAMM50 sorting and assembly machinery component 9.92 9.6 -0.05 0.06 0.12 0.0 Detail
545 ESCA cuproptosis SARS2 seryl-tRNA synthetase 2, mitochondrial 8.41 8.82 0.07 0.24 0.35 0.0 Detail
546 ESCA cuproptosis SCAP SREBF chaperone 11.19 10.85 -0.04 0.03 0.08 0.0 Detail
547 ESCA cuproptosis SDHA succinate dehydrogenase complex flavoprotein subunit A 11.72 11.36 -0.05 0.07 0.14 0.0 Detail
548 ESCA cuproptosis SDHAF2 succinate dehydrogenase complex assembly factor 2 9.05 9.33 0.04 0.04 0.09 0.0 Detail
549 ESCA cuproptosis SDHB succinate dehydrogenase complex iron sulfur subunit B 10.33 10.28 -0.01 0.47 0.59 0.0 Detail
550 ESCA cuproptosis SDHC succinate dehydrogenase complex subunit C 10.06 10.17 0.02 0.57 0.68 0.0 Detail
551 ESCA cuproptosis SDHD succinate dehydrogenase complex subunit D 11.0 10.68 -0.04 0.03 0.07 0.0 Detail
552 ESCA cuproptosis SDSL serine dehydratase like 6.17 6.48 0.07 0.96 0.98 0.0 Detail
553 ESCA cuproptosis SEC14L2 SEC14 like lipid binding 2 7.89 8.21 0.06 0.3 0.41 0.0 Detail
554 ESCA cuproptosis SEPTIN1 septin 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
555 ESCA cuproptosis SERPINE1 serpin family E member 1 10.61 11.65 0.13 0.09 0.17 0.0 Detail
556 ESCA cuproptosis SGF29 SAGA complex associated factor 29 0.0 0.0 0.0 0.0 0.0 0.0 Detail
557 ESCA cuproptosis SLC16A6 solute carrier family 16 member 6 4.74 5.08 0.1 0.14 0.23 0.0 Detail
558 ESCA cuproptosis SLC25A39 solute carrier family 25 member 39 11.01 11.65 0.08 0.04 0.1 0.0 Detail
559 ESCA cuproptosis SLC25A51 solute carrier family 25 member 51 0.0 0.0 0.0 0.0 0.0 0.0 Detail
560 ESCA cuproptosis SLC30A7 solute carrier family 30 member 7 10.27 10.6 0.05 0.16 0.26 0.0 Detail
561 ESCA cuproptosis SLC33A1 solute carrier family 33 member 1 9.38 9.61 0.04 0.3 0.41 0.0 Detail
562 ESCA cuproptosis SLC52A2 solute carrier family 52 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
563 ESCA cuproptosis SLC7A11 solute carrier family 7 member 11 8.31 10.09 0.28 0.09 0.17 0.0 Detail
564 ESCA cuproptosis SLC7A5 solute carrier family 7 member 5 12.11 12.8 0.08 0.17 0.27 0.0 Detail
565 ESCA cuproptosis SLFN11 schlafen family member 11 8.48 9.38 0.15 0.03 0.07 0.0 Detail
566 ESCA cuproptosis SMAD3-AS1 SMAD3 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
567 ESCA cuproptosis SNAPIN SNAP associated protein 8.34 8.58 0.04 0.13 0.22 0.0 Detail
568 ESCA cuproptosis SOD1 superoxide dismutase 1 11.04 11.19 0.02 0.51 0.63 0.0 Detail
569 ESCA cuproptosis SOD2 superoxide dismutase 2 12.14 12.65 0.06 0.11 0.19 0.0 Detail
570 ESCA cuproptosis SOX2 SRY-box transcription factor 2 8.34 7.74 -0.11 0.79 0.86 0.0 Detail
571 ESCA cuproptosis sp1 Sp1 transcription factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
572 ESCA cuproptosis SP1 Sp1 transcription factor 11.79 11.98 0.02 0.07 0.13 0.0 Detail
573 ESCA cuproptosis SPATA13 spermatogenesis associated 13 9.02 8.77 -0.04 0.6 0.7 0.0 Detail
574 ESCA cuproptosis SPDYE1 speedy/RINGO cell cycle regulator family member E1 4.6 4.84 0.08 0.47 0.59 0.0 Detail
575 ESCA cuproptosis SRP54 signal recognition particle 54 9.68 10.01 0.05 0.02 0.06 0.0 Detail
576 ESCA cuproptosis STARD7 StAR related lipid transfer domain containing 7 11.24 11.61 0.05 0.04 0.09 0.0 Detail
577 ESCA cuproptosis STEAP4 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
578 ESCA cuproptosis STEAP STEAP family member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
579 ESCA cuproptosis STK11 serine/threonine kinase 11 10.31 10.12 -0.03 0.34 0.46 0.0 Detail
580 ESCA cuproptosis TANK TRAF family member associated NFKB activator 9.68 9.85 0.02 0.16 0.26 0.0 Detail
581 ESCA cuproptosis TARS2 threonyl-tRNA synthetase 2, mitochondrial 8.65 9.01 0.06 0.06 0.12 0.0 Detail
582 ESCA cuproptosis TEDC1 tubulin epsilon and delta complex 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
583 ESCA cuproptosis TEFM transcription elongation factor, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 Detail
584 ESCA cuproptosis TFAM transcription factor A, mitochondrial 8.69 9.13 0.07 0.04 0.08 0.0 Detail
585 ESCA cuproptosis TIMM9 translocase of inner mitochondrial membrane 9 8.57 8.81 0.04 0.08 0.15 0.0 Detail
586 ESCA cuproptosis TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
587 ESCA cuproptosis TMEM191B transmembrane protein 191B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
588 ESCA cuproptosis TP53 tumor protein p53 9.66 10.31 0.09 0.03 0.08 0.0 Detail
589 ESCA cuproptosis TPK1 thiamin pyrophosphokinase 1 6.07 6.11 0.01 0.89 0.93 0.0 Detail
590 ESCA cuproptosis TRAPPC11 trafficking protein particle complex subunit 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
591 ESCA cuproptosis TRIM32 tripartite motif containing 32 8.39 8.61 0.04 0.16 0.26 0.0 Detail
592 ESCA cuproptosis TSC22D2 TSC22 domain family member 2 10.54 10.02 -0.07 0.11 0.2 0.0 Detail
593 ESCA cuproptosis TUBGCP4 tubulin gamma complex component 4 8.52 8.75 0.04 0.12 0.21 0.0 Detail
594 ESCA cuproptosis TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 8.54 8.63 0.01 0.87 0.92 0.0 Detail
595 ESCA cuproptosis TWNK twinkle mtDNA helicase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
596 ESCA cuproptosis TYR tyrosinase 0.04 0.18 2.1 0.26 0.38 0.0 Detail
597 ESCA cuproptosis U2SURP U2 snRNP associated SURP domain containing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
598 ESCA cuproptosis UBE2D2 ubiquitin conjugating enzyme E2 D2 10.49 10.63 0.02 0.2 0.31 0.0 Detail
599 ESCA cuproptosis UBE2D3 ubiquitin conjugating enzyme E2 D3 11.88 11.73 -0.02 0.18 0.28 0.0 Detail
600 ESCA cuproptosis UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 7.95 7.56 -0.07 0.08 0.15 0.0 Detail
601 ESCA cuproptosis UlK1 unc-51 like autophagy activating kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
602 ESCA cuproptosis UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
603 ESCA cuproptosis UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
604 ESCA cuproptosis UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 10.03 9.98 -0.01 0.54 0.65 0.0 Detail
605 ESCA cuproptosis USE1 unconventional SNARE in the ER 1 7.73 7.8 0.01 0.8 0.87 0.0 Detail
606 ESCA cuproptosis UTP25 UTP25 small subunit processome component 0.0 0.0 0.0 0.0 0.0 0.0 Detail
607 ESCA cuproptosis VARS2 valyl-tRNA synthetase 2, mitochondrial 9.17 9.38 0.03 0.65 0.74 0.0 Detail
608 ESCA cuproptosis VEGFA vascular endothelial growth factor A 11.09 11.66 0.07 0.06 0.13 0.0 Detail
609 ESCA cuproptosis VPS45 vacuolar protein sorting 45 homolog 9.49 9.47 -0.0 0.81 0.88 0.0 Detail
610 ESCA cuproptosis WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 8.35 8.4 0.01 0.97 0.98 0.0 Detail
611 ESCA cuproptosis xCT solute carrier family 7 member 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
612 ESCA cuproptosis XRN1 5'-3' exoribonuclease 1 10.27 10.69 0.06 0.03 0.07 0.0 Detail
613 ESCA cuproptosis YAE1 YAE1 maturation factor of ABCE1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
614 ESCA cuproptosis YAP1 Yes1 associated transcriptional regulator 12.08 11.63 -0.05 0.03 0.08 0.0 Detail
615 ESCA cuproptosis ZBP1 Z-DNA binding protein 1 3.67 5.19 0.5 0.02 0.06 0.0 Detail
616 ESCA cuproptosis ZBTB11 zinc finger and BTB domain containing 11 9.82 10.04 0.03 0.17 0.27 0.0 Detail
617 ESCA cuproptosis ZFAT zinc finger and AT-hook domain containing 7.96 8.12 0.03 0.23 0.34 0.0 Detail
618 ESCA cuproptosis ZKSCAN5 zinc finger with KRAB and SCAN domains 5 8.28 8.64 0.06 0.06 0.12 0.0 Detail
619 ESCA cuproptosis ZNF341 zinc finger protein 341 7.21 7.33 0.02 0.41 0.54 0.0 Detail
620 ESCA cuproptosis ZNF365 zinc finger protein 365 5.59 5.39 -0.05 0.97 0.98 0.0 Detail

Ensemble learning for ESCA based on specific cuproptosis gene regulaors.