Disease associated with RCD disease & gene list




KICH specific anoikis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 KICH anoikis NTRK2 neurotrophic receptor tyrosine kinase 2 11.06 5.42 -1.03 0.0 0.0 100.0 Detail
2 KICH anoikis E2F1 E2F transcription factor 1 4.59 7.98 0.8 0.0 0.0 98.8 Detail
3 KICH anoikis PDK4 pyruvate dehydrogenase kinase 4 12.97 9.84 -0.4 0.0 0.0 87.95 Detail
4 KICH anoikis TFDP1 transcription factor Dp-1 10.46 9.6 -0.12 0.0 0.0 81.53 Detail
5 KICH anoikis ITGB1 integrin subunit beta 1 13.11 12.16 -0.11 0.0 0.0 77.51 Detail
6 KICH anoikis TLE1 TLE family member 1, transcriptional corepressor 9.22 10.56 0.2 0.0 0.0 72.29 Detail
7 KICH anoikis SNAI2 snail family transcriptional repressor 2 7.75 6.0 -0.37 0.0 0.0 71.49 Detail
8 KICH anoikis IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 8.57 9.17 0.1 0.0 0.0 67.07 Detail
9 KICH anoikis ANKRD13C ankyrin repeat domain 13C 9.07 8.56 -0.08 0.0 0.0 61.45 Detail
10 KICH anoikis MYBBP1A MYB binding protein 1a 8.77 9.39 0.1 0.0 0.0 61.45 Detail
11 KICH anoikis STK11 serine/threonine kinase 11 10.08 10.67 0.08 0.0 0.0 60.24 Detail
12 KICH anoikis BCL2 BCL2 apoptosis regulator 9.89 10.88 0.14 0.0 0.0 59.44 Detail
13 KICH anoikis BCL2L1 BCL2 like 1 12.06 12.84 0.09 0.0 0.0 59.44 Detail
14 KICH anoikis BRMS1 BRMS1 transcriptional repressor and anoikis regulator 9.76 10.29 0.08 0.0 0.0 55.82 Detail
15 KICH anoikis CAV1 caveolin 1 10.17 11.43 0.17 0.0 0.0 45.38 Detail
16 KICH anoikis MCL1 MCL1 apoptosis regulator, BCL2 family member 12.67 11.81 -0.1 0.0 0.0 42.57 Detail
17 KICH anoikis TSC2 TSC complex subunit 2 10.34 10.77 0.06 0.0 0.0 40.16 Detail
18 KICH anoikis MAP3K7 mitogen-activated protein kinase kinase kinase 7 9.24 8.88 -0.06 0.0 0.0 28.51 Detail
19 KICH anoikis NOTCH1 notch receptor 1 10.05 9.51 -0.08 0.01 0.02 4.02 Detail
20 KICH anoikis BMF Bcl2 modifying factor 9.25 9.47 0.03 0.26 0.34 0.0 Detail
21 KICH anoikis CHEK2 checkpoint kinase 2 5.7 5.22 -0.13 0.02 0.02 0.0 Detail
22 KICH anoikis CRYBA1 crystallin beta A1 0.05 0.16 1.67 0.16 0.23 0.0 Detail
23 KICH anoikis DAPK2 death associated protein kinase 2 6.7 7.16 0.1 0.28 0.35 0.0 Detail
24 KICH anoikis ITGA5 integrin subunit alpha 5 9.85 9.93 0.01 0.96 0.96 0.0 Detail
25 KICH anoikis PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 8.52 8.53 0.0 0.93 0.96 0.0 Detail
26 KICH anoikis PTK2 protein tyrosine kinase 2 11.31 11.17 -0.02 0.34 0.41 0.0 Detail
27 KICH anoikis PTRH2 peptidyl-tRNA hydrolase 2 7.61 7.65 0.01 0.93 0.96 0.0 Detail
28 KICH anoikis SIK1 salt inducible kinase 1 11.1 10.91 -0.03 0.51 0.59 0.0 Detail
29 KICH anoikis SRC SRC proto-oncogene, non-receptor tyrosine kinase 10.13 10.08 -0.01 0.79 0.88 0.0 Detail

Ensemble learning for KICH based on specific anoikis gene regulaors.