Disease associated with RCD disease & gene list




KIRC specific cuproptosis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 KIRC cuproptosis AQP2 aquaporin 2 15.32 2.24 -2.77 0.0 0.0 100.0 Detail
2 KIRC cuproptosis CDKN2A cyclin dependent kinase inhibitor 2A 1.46 6.46 2.15 0.0 0.0 98.68 Detail
3 KIRC cuproptosis DBT dihydrolipoamide branched chain transacylase E2 10.91 9.35 -0.22 0.0 0.0 97.09 Detail
4 KIRC cuproptosis MLKL mixed lineage kinase domain like pseudokinase 6.98 8.81 0.34 0.0 0.0 94.02 Detail
5 KIRC cuproptosis SHMT2 serine hydroxymethyltransferase 2 10.12 12.02 0.25 0.0 0.0 93.62 Detail
6 KIRC cuproptosis VEGFA vascular endothelial growth factor A 11.55 14.76 0.35 0.0 0.0 93.25 Detail
7 KIRC cuproptosis ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 5.68 1.73 -1.72 0.0 0.0 92.63 Detail
8 KIRC cuproptosis NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 11.72 10.35 -0.18 0.0 0.0 91.49 Detail
9 KIRC cuproptosis MAL2 mal, T cell differentiation protein 2 12.29 9.02 -0.45 0.0 0.0 90.05 Detail
10 KIRC cuproptosis PDHB pyruvate dehydrogenase E1 subunit beta 11.0 9.82 -0.16 0.0 0.0 89.66 Detail
11 KIRC cuproptosis UBE2I ubiquitin conjugating enzyme E2 I 9.96 10.61 0.09 0.0 0.0 89.51 Detail
12 KIRC cuproptosis SLC16A1 solute carrier family 16 member 1 8.7 10.88 0.32 0.0 0.0 89.15 Detail
13 KIRC cuproptosis GLRX5 glutaredoxin 5 10.35 9.18 -0.17 0.0 0.0 89.1 Detail
14 KIRC cuproptosis RSL1D1 ribosomal L1 domain containing 1 11.19 11.85 0.08 0.0 0.0 89.03 Detail
15 KIRC cuproptosis PDK1 pyruvate dehydrogenase kinase 1 8.38 10.35 0.3 0.0 0.0 88.74 Detail
16 KIRC cuproptosis LARS2 leucyl-tRNA synthetase 2, mitochondrial 9.85 8.3 -0.25 0.0 0.0 88.53 Detail
17 KIRC cuproptosis FDX1 ferredoxin 1 10.18 9.03 -0.17 0.0 0.0 88.44 Detail
18 KIRC cuproptosis FOXM1 forkhead box M1 5.18 7.62 0.56 0.0 0.0 87.86 Detail
19 KIRC cuproptosis MCM5 minichromosome maintenance complex component 5 8.82 9.96 0.18 0.0 0.0 87.48 Detail
20 KIRC cuproptosis ALAS1 5'-aminolevulinate synthase 1 10.5 9.39 -0.16 0.0 0.0 87.14 Detail
21 KIRC cuproptosis TPI1 triosephosphate isomerase 1 13.22 14.21 0.1 0.0 0.0 87.12 Detail
22 KIRC cuproptosis PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 11.84 10.63 -0.16 0.0 0.0 87.07 Detail
23 KIRC cuproptosis STARD7 StAR related lipid transfer domain containing 7 12.16 11.54 -0.08 0.0 0.0 86.91 Detail
24 KIRC cuproptosis NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial 8.78 7.85 -0.16 0.0 0.0 86.6 Detail
25 KIRC cuproptosis CCL5 C-C motif chemokine ligand 5 7.12 10.15 0.51 0.0 0.0 86.53 Detail
26 KIRC cuproptosis PFKP phosphofructokinase, platelet 11.0 13.19 0.26 0.0 0.0 86.25 Detail
27 KIRC cuproptosis RPS19 ribosomal protein S19 12.27 13.61 0.15 0.0 0.0 86.12 Detail
28 KIRC cuproptosis SCO1 synthesis of cytochrome C oxidase 1 9.32 8.53 -0.13 0.0 0.0 85.99 Detail
29 KIRC cuproptosis YEATS2 YEATS domain containing 2 9.25 10.33 0.16 0.0 0.0 85.96 Detail
30 KIRC cuproptosis SCAP SREBF chaperone 10.8 9.95 -0.12 0.0 0.0 85.92 Detail
31 KIRC cuproptosis FASLG Fas ligand 2.26 5.27 1.22 0.0 0.0 85.45 Detail
32 KIRC cuproptosis DLST dihydrolipoamide S-succinyltransferase 12.13 11.15 -0.12 0.0 0.0 85.32 Detail
33 KIRC cuproptosis SDHD succinate dehydrogenase complex subunit D 12.07 11.02 -0.13 0.0 0.0 85.11 Detail
34 KIRC cuproptosis NARS2 asparaginyl-tRNA synthetase 2, mitochondrial 9.03 8.25 -0.13 0.0 0.0 85.0 Detail
35 KIRC cuproptosis MFN2 mitofusin 2 11.81 11.12 -0.09 0.0 0.0 84.8 Detail
36 KIRC cuproptosis ATF4 activating transcription factor 4 11.43 12.38 0.11 0.0 0.0 84.53 Detail
37 KIRC cuproptosis LOXL2 lysyl oxidase like 2 7.93 10.95 0.46 0.0 0.0 84.5 Detail
38 KIRC cuproptosis ACLY ATP citrate lyase 11.82 13.09 0.15 0.0 0.0 84.44 Detail
39 KIRC cuproptosis DLD dihydrolipoamide dehydrogenase 11.88 10.86 -0.13 0.0 0.0 84.27 Detail
40 KIRC cuproptosis SPARC secreted protein acidic and cysteine rich 13.88 15.71 0.18 0.0 0.0 84.12 Detail
41 KIRC cuproptosis CAT catalase 12.95 11.64 -0.15 0.0 0.0 83.91 Detail
42 KIRC cuproptosis GFM1 G elongation factor mitochondrial 1 10.76 9.8 -0.14 0.0 0.0 83.49 Detail
43 KIRC cuproptosis FDXR ferredoxin reductase 7.68 8.94 0.22 0.0 0.0 83.39 Detail
44 KIRC cuproptosis RTEL1 regulator of telomere elongation helicase 1 7.51 8.76 0.22 0.0 0.0 83.11 Detail
45 KIRC cuproptosis NDUFA4 NDUFA4 mitochondrial complex associated 12.16 10.96 -0.15 0.0 0.0 83.08 Detail
46 KIRC cuproptosis PPA2 inorganic pyrophosphatase 2 10.46 9.53 -0.13 0.0 0.0 82.54 Detail
47 KIRC cuproptosis PDE12 phosphodiesterase 12 9.57 8.67 -0.14 0.0 0.0 82.36 Detail
48 KIRC cuproptosis NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 11.73 10.95 -0.1 0.0 0.0 81.93 Detail
49 KIRC cuproptosis PRC1 protein regulator of cytokinesis 1 6.57 8.07 0.3 0.0 0.0 81.89 Detail
50 KIRC cuproptosis SLFN11 schlafen family member 11 8.73 10.35 0.25 0.0 0.0 81.82 Detail
51 KIRC cuproptosis CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X 9.84 9.14 -0.11 0.0 0.0 81.65 Detail
52 KIRC cuproptosis UQCRC1 ubiquinol-cytochrome c reductase core protein 1 12.39 11.18 -0.15 0.0 0.0 81.57 Detail
53 KIRC cuproptosis FKBP4 FKBP prolyl isomerase 4 11.82 11.0 -0.1 0.0 0.0 81.3 Detail
54 KIRC cuproptosis ACD ACD shelterin complex subunit and telomerase recruitment factor 7.8 8.55 0.13 0.0 0.0 81.13 Detail
55 KIRC cuproptosis RPLP0 ribosomal protein lateral stalk subunit P0 13.42 14.44 0.11 0.0 0.0 80.93 Detail
56 KIRC cuproptosis OGDHL oxoglutarate dehydrogenase L 12.65 9.67 -0.39 0.0 0.0 80.73 Detail
57 KIRC cuproptosis PLOD1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 11.31 12.44 0.14 0.0 0.0 80.5 Detail
58 KIRC cuproptosis DLAT dihydrolipoamide S-acetyltransferase 10.74 9.96 -0.11 0.0 0.0 80.28 Detail
59 KIRC cuproptosis TFAM transcription factor A, mitochondrial 9.37 8.7 -0.11 0.0 0.0 79.86 Detail
60 KIRC cuproptosis ANLN anillin, actin binding protein 4.93 7.41 0.59 0.0 0.0 79.79 Detail
61 KIRC cuproptosis LOX lysyl oxidase 8.2 11.67 0.51 0.0 0.0 79.78 Detail
62 KIRC cuproptosis ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) 8.49 9.83 0.21 0.0 0.0 79.62 Detail
63 KIRC cuproptosis POLG DNA polymerase gamma, catalytic subunit 9.64 10.36 0.1 0.0 0.0 79.62 Detail
64 KIRC cuproptosis PSMD6 proteasome 26S subunit, non-ATPase 6 10.26 9.59 -0.1 0.0 0.0 79.41 Detail
65 KIRC cuproptosis ISCU iron-sulfur cluster assembly enzyme 11.72 10.91 -0.1 0.0 0.0 79.28 Detail
66 KIRC cuproptosis CDKN3 cyclin dependent kinase inhibitor 3 3.23 5.21 0.69 0.0 0.0 79.2 Detail
67 KIRC cuproptosis SOD3 superoxide dismutase 3 10.9 9.22 -0.24 0.0 0.0 78.79 Detail
68 KIRC cuproptosis SDHC succinate dehydrogenase complex subunit C 11.98 11.13 -0.11 0.0 0.0 78.74 Detail
69 KIRC cuproptosis MT1H metallothionein 1H 8.86 2.87 -1.63 0.0 0.0 78.28 Detail
70 KIRC cuproptosis UBE2D2 ubiquitin conjugating enzyme E2 D2 10.53 11.06 0.07 0.0 0.0 77.91 Detail
71 KIRC cuproptosis DAXX death domain associated protein 9.66 10.18 0.08 0.0 0.0 77.67 Detail
72 KIRC cuproptosis FXN frataxin 7.95 7.26 -0.13 0.0 0.0 77.56 Detail
73 KIRC cuproptosis ZBP1 Z-DNA binding protein 1 2.21 4.72 1.09 0.0 0.0 77.41 Detail
74 KIRC cuproptosis SDHB succinate dehydrogenase complex iron sulfur subunit B 11.32 10.43 -0.12 0.0 0.0 77.21 Detail
75 KIRC cuproptosis MT1G metallothionein 1G 11.79 6.27 -0.91 0.0 0.0 77.07 Detail
76 KIRC cuproptosis NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 11.93 11.14 -0.1 0.0 0.0 76.96 Detail
77 KIRC cuproptosis DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 11.1 10.09 -0.14 0.0 0.0 76.47 Detail
78 KIRC cuproptosis PDHX pyruvate dehydrogenase complex component X 9.49 8.99 -0.08 0.0 0.0 76.45 Detail
79 KIRC cuproptosis GLS glutaminase 13.16 12.08 -0.12 0.0 0.0 75.8 Detail
80 KIRC cuproptosis MPI mannose phosphate isomerase 9.7 10.54 0.12 0.0 0.0 75.77 Detail
81 KIRC cuproptosis MOXD1 monooxygenase DBH like 1 10.02 7.03 -0.51 0.0 0.0 75.47 Detail
82 KIRC cuproptosis SLC7A11 solute carrier family 7 member 11 3.87 5.77 0.58 0.0 0.0 74.86 Detail
83 KIRC cuproptosis API5 apoptosis inhibitor 5 11.32 10.91 -0.05 0.0 0.0 74.73 Detail
84 KIRC cuproptosis RPS25 ribosomal protein S25 12.47 13.17 0.08 0.0 0.0 74.65 Detail
85 KIRC cuproptosis ISG15 ISG15 ubiquitin like modifier 7.69 9.31 0.28 0.0 0.0 74.49 Detail
86 KIRC cuproptosis OSBPL9 oxysterol binding protein like 9 11.59 11.05 -0.07 0.0 0.0 74.08 Detail
87 KIRC cuproptosis ATP8B1 ATPase phospholipid transporting 8B1 10.24 8.95 -0.19 0.0 0.0 73.94 Detail
88 KIRC cuproptosis FAS Fas cell surface death receptor 8.27 9.44 0.19 0.0 0.0 73.84 Detail
89 KIRC cuproptosis IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha 10.56 10.02 -0.08 0.0 0.0 73.8 Detail
90 KIRC cuproptosis BECN1 beclin 1 10.68 10.3 -0.05 0.0 0.0 72.5 Detail
91 KIRC cuproptosis RPL19 ribosomal protein L19 13.54 14.23 0.07 0.0 0.0 72.46 Detail
92 KIRC cuproptosis SLC11A2 solute carrier family 11 member 2 10.58 9.97 -0.08 0.0 0.0 72.26 Detail
93 KIRC cuproptosis C6orf136 chromosome 6 open reading frame 136 8.71 7.75 -0.17 0.0 0.0 72.02 Detail
94 KIRC cuproptosis CYCS cytochrome c, somatic 12.03 11.06 -0.12 0.0 0.0 71.74 Detail
95 KIRC cuproptosis DNM1L dynamin 1 like 10.83 10.36 -0.06 0.0 0.0 71.28 Detail
96 KIRC cuproptosis HSPH1 heat shock protein family H (Hsp110) member 1 10.8 10.0 -0.11 0.0 0.0 70.9 Detail
97 KIRC cuproptosis HCCS holocytochrome c synthase 9.25 8.81 -0.07 0.0 0.0 70.7 Detail
98 KIRC cuproptosis KLF5 KLF transcription factor 5 9.31 7.74 -0.27 0.0 0.0 70.45 Detail
99 KIRC cuproptosis SDSL serine dehydratase like 9.15 8.08 -0.18 0.0 0.0 70.11 Detail
100 KIRC cuproptosis XIAP X-linked inhibitor of apoptosis 10.88 10.4 -0.07 0.0 0.0 70.07 Detail
101 KIRC cuproptosis SLC31A1 solute carrier family 31 member 1 10.68 9.82 -0.12 0.0 0.0 69.85 Detail
102 KIRC cuproptosis ACO1 aconitase 1 11.89 10.71 -0.15 0.0 0.0 69.84 Detail
103 KIRC cuproptosis CP ceruloplasmin 8.14 12.13 0.58 0.0 0.0 69.77 Detail
104 KIRC cuproptosis COX11 cytochrome c oxidase copper chaperone COX11 10.48 9.98 -0.07 0.0 0.0 69.24 Detail
105 KIRC cuproptosis CYP1A1 cytochrome P450 family 1 subfamily A member 1 3.55 0.91 -1.96 0.0 0.0 68.89 Detail
106 KIRC cuproptosis MRPS16 mitochondrial ribosomal protein S16 10.73 10.3 -0.06 0.0 0.0 68.78 Detail
107 KIRC cuproptosis PGK1 phosphoglycerate kinase 1 13.43 14.26 0.09 0.0 0.0 68.5 Detail
108 KIRC cuproptosis HAUS5 HAUS augmin like complex subunit 5 7.36 8.12 0.14 0.0 0.0 68.02 Detail
109 KIRC cuproptosis SLC25A3 solute carrier family 25 member 3 13.19 12.66 -0.06 0.0 0.0 67.95 Detail
110 KIRC cuproptosis GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 11.18 10.71 -0.06 0.0 0.0 67.65 Detail
111 KIRC cuproptosis IDH2 isocitrate dehydrogenase (NADP(+)) 2 12.54 11.5 -0.12 0.0 0.0 67.36 Detail
112 KIRC cuproptosis NFS1 NFS1 cysteine desulfurase 10.09 9.45 -0.09 0.0 0.0 66.78 Detail
113 KIRC cuproptosis ISCA2 iron-sulfur cluster assembly 2 8.86 8.25 -0.1 0.0 0.0 66.75 Detail
114 KIRC cuproptosis ETFDH electron transfer flavoprotein dehydrogenase 10.12 9.33 -0.12 0.0 0.0 66.1 Detail
115 KIRC cuproptosis MRPL34 mitochondrial ribosomal protein L34 10.06 9.26 -0.12 0.0 0.0 65.94 Detail
116 KIRC cuproptosis RPL28 ribosomal protein L28 12.26 13.2 0.11 0.0 0.0 65.87 Detail
117 KIRC cuproptosis VPS45 vacuolar protein sorting 45 homolog 9.62 9.27 -0.05 0.0 0.0 65.7 Detail
118 KIRC cuproptosis POLD1 DNA polymerase delta 1, catalytic subunit 7.5 8.23 0.13 0.0 0.0 65.51 Detail
119 KIRC cuproptosis FASTKD5 FAST kinase domains 5 9.22 8.58 -0.1 0.0 0.0 65.34 Detail
120 KIRC cuproptosis UBA2 ubiquitin like modifier activating enzyme 2 10.63 11.02 0.05 0.0 0.0 65.34 Detail
121 KIRC cuproptosis USE1 unconventional SNARE in the ER 1 7.93 8.63 0.12 0.0 0.0 65.14 Detail
122 KIRC cuproptosis MT1F metallothionein 1F 10.31 7.72 -0.42 0.0 0.0 64.94 Detail
123 KIRC cuproptosis UQCRC2 ubiquinol-cytochrome c reductase core protein 2 12.36 11.76 -0.07 0.0 0.0 64.69 Detail
124 KIRC cuproptosis BRCA1 BRCA1 DNA repair associated 6.33 7.11 0.17 0.0 0.0 64.29 Detail
125 KIRC cuproptosis FAU FAU ubiquitin like and ribosomal protein S30 fusion 12.01 12.76 0.09 0.0 0.0 64.24 Detail
126 KIRC cuproptosis EXOC3 exocyst complex component 3 10.27 10.9 0.09 0.0 0.0 63.5 Detail
127 KIRC cuproptosis TPK1 thiamin pyrophosphokinase 1 7.06 7.83 0.15 0.0 0.0 63.46 Detail
128 KIRC cuproptosis TP53 tumor protein p53 9.48 10.04 0.08 0.0 0.0 63.44 Detail
129 KIRC cuproptosis NOP2 NOP2 nucleolar protein 8.36 9.05 0.11 0.0 0.0 63.41 Detail
130 KIRC cuproptosis SPATA13 spermatogenesis associated 13 9.88 8.83 -0.16 0.0 0.0 63.14 Detail
131 KIRC cuproptosis TLR3 toll like receptor 3 9.02 10.31 0.19 0.0 0.0 63.07 Detail
132 KIRC cuproptosis HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 10.57 9.95 -0.09 0.0 0.0 62.94 Detail
133 KIRC cuproptosis MRPS25 mitochondrial ribosomal protein S25 9.83 9.12 -0.11 0.0 0.0 62.76 Detail
134 KIRC cuproptosis TOP1MT DNA topoisomerase I mitochondrial 8.05 8.7 0.11 0.0 0.0 62.66 Detail
135 KIRC cuproptosis PTCD3 pentatricopeptide repeat domain 3 10.19 9.8 -0.06 0.0 0.0 62.27 Detail
136 KIRC cuproptosis CMC1 C-X9-C motif containing 1 7.63 6.94 -0.14 0.0 0.0 62.25 Detail
137 KIRC cuproptosis DNA2 DNA replication helicase/nuclease 2 4.37 5.72 0.39 0.0 0.0 61.89 Detail
138 KIRC cuproptosis CDC16 cell division cycle 16 10.15 10.49 0.05 0.0 0.0 61.88 Detail
139 KIRC cuproptosis MRPS9 mitochondrial ribosomal protein S9 9.33 8.94 -0.06 0.0 0.0 61.73 Detail
140 KIRC cuproptosis QRSL1 glutaminyl-tRNA amidotransferase subunit QRSL1 9.13 8.64 -0.08 0.0 0.0 61.45 Detail
141 KIRC cuproptosis HSPA8 heat shock protein family A (Hsp70) member 8 14.81 14.0 -0.08 0.0 0.0 61.42 Detail
142 KIRC cuproptosis MTO1 mitochondrial tRNA translation optimization 1 9.18 8.75 -0.07 0.0 0.0 61.4 Detail
143 KIRC cuproptosis LDLR low density lipoprotein receptor 9.7 8.04 -0.27 0.0 0.0 61.39 Detail
144 KIRC cuproptosis CUTC cutC copper transporter 7.9 8.24 0.06 0.0 0.0 61.11 Detail
145 KIRC cuproptosis NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 10.87 10.35 -0.07 0.0 0.0 60.73 Detail
146 KIRC cuproptosis MRPL15 mitochondrial ribosomal protein L15 10.26 9.69 -0.08 0.0 0.0 60.53 Detail
147 KIRC cuproptosis COX18 cytochrome c oxidase assembly factor COX18 8.93 8.41 -0.09 0.0 0.0 60.48 Detail
148 KIRC cuproptosis SLC16A6 solute carrier family 16 member 6 4.33 5.7 0.4 0.0 0.0 60.47 Detail
149 KIRC cuproptosis NDUFA9 NADH:ubiquinone oxidoreductase subunit A9 10.95 10.38 -0.08 0.0 0.0 60.42 Detail
150 KIRC cuproptosis SLC25A26 solute carrier family 25 member 26 8.68 8.16 -0.09 0.0 0.0 60.41 Detail
151 KIRC cuproptosis NDUFA6 NADH:ubiquinone oxidoreductase subunit A6 10.74 10.14 -0.08 0.0 0.0 60.27 Detail
152 KIRC cuproptosis SLC25A39 solute carrier family 25 member 39 11.64 10.94 -0.09 0.0 0.0 60.21 Detail
153 KIRC cuproptosis SLC30A7 solute carrier family 30 member 7 9.7 10.14 0.06 0.0 0.0 59.93 Detail
154 KIRC cuproptosis TMEM199 transmembrane protein 199 8.92 8.67 -0.04 0.0 0.0 59.79 Detail
155 KIRC cuproptosis MRPS14 mitochondrial ribosomal protein S14 8.58 8.25 -0.06 0.0 0.0 59.37 Detail
156 KIRC cuproptosis RPL3 ribosomal protein L3 14.73 15.22 0.05 0.0 0.0 59.04 Detail
157 KIRC cuproptosis FGD6 FYVE, RhoGEF and PH domain containing 6 8.73 9.48 0.12 0.0 0.0 58.81 Detail
158 KIRC cuproptosis POLE DNA polymerase epsilon, catalytic subunit 8.2 8.83 0.11 0.0 0.0 58.32 Detail
159 KIRC cuproptosis NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 11.0 10.45 -0.07 0.0 0.0 57.94 Detail
160 KIRC cuproptosis RPL7A ribosomal protein L7a 13.27 13.82 0.06 0.0 0.0 57.74 Detail
161 KIRC cuproptosis CENPJ centromere protein J 6.19 6.83 0.14 0.0 0.0 57.35 Detail
162 KIRC cuproptosis MTBP MDM2 binding protein 4.87 5.56 0.19 0.0 0.0 57.33 Detail
163 KIRC cuproptosis CCDC137 coiled-coil domain containing 137 7.91 8.42 0.09 0.0 0.0 57.05 Detail
164 KIRC cuproptosis RPL10A ribosomal protein L10a 12.64 13.17 0.06 0.0 0.0 57.03 Detail
165 KIRC cuproptosis FAM111A FAM111 trypsin like peptidase A 9.21 9.88 0.1 0.0 0.0 56.93 Detail
166 KIRC cuproptosis AHR aryl hydrocarbon receptor 10.26 10.98 0.1 0.0 0.0 56.3 Detail
167 KIRC cuproptosis RAD9A RAD9 checkpoint clamp component A 6.97 7.69 0.14 0.0 0.0 55.98 Detail
168 KIRC cuproptosis NLRP3 NLR family pyrin domain containing 3 5.48 6.91 0.34 0.0 0.0 55.93 Detail
169 KIRC cuproptosis PRDX1 peroxiredoxin 1 12.9 12.4 -0.06 0.0 0.0 55.88 Detail
170 KIRC cuproptosis CS citrate synthase 12.11 11.74 -0.05 0.0 0.0 55.83 Detail
171 KIRC cuproptosis NFE2L2 NFE2 like bZIP transcription factor 2 11.97 11.49 -0.06 0.0 0.0 55.76 Detail
172 KIRC cuproptosis AQP1 aquaporin 1 (Colton blood group) 14.99 13.69 -0.13 0.0 0.0 55.66 Detail
173 KIRC cuproptosis APP amyloid beta precursor protein 15.57 14.93 -0.06 0.0 0.0 54.98 Detail
174 KIRC cuproptosis ATM ATM serine/threonine kinase 10.12 10.72 0.08 0.0 0.0 54.95 Detail
175 KIRC cuproptosis EGFR epidermal growth factor receptor 10.08 11.21 0.15 0.0 0.0 54.68 Detail
176 KIRC cuproptosis ISCA1 iron-sulfur cluster assembly 1 10.42 10.0 -0.06 0.0 0.0 54.67 Detail
177 KIRC cuproptosis NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 11.58 10.94 -0.08 0.0 0.0 54.55 Detail
178 KIRC cuproptosis ALB albumin 9.7 4.78 -1.02 0.0 0.0 54.53 Detail
179 KIRC cuproptosis ANKRD9 ankyrin repeat domain 9 6.66 5.57 -0.26 0.0 0.0 54.11 Detail
180 KIRC cuproptosis PRND prion like protein doppel 2.81 5.36 0.93 0.0 0.0 53.9 Detail
181 KIRC cuproptosis RPS27A ribosomal protein S27a 12.51 13.03 0.06 0.0 0.0 53.75 Detail
182 KIRC cuproptosis ARF1 ADP ribosylation factor 1 12.93 13.26 0.04 0.0 0.0 53.74 Detail
183 KIRC cuproptosis PTPMT1 protein tyrosine phosphatase mitochondrial 1 9.6 9.17 -0.07 0.0 0.0 53.4 Detail
184 KIRC cuproptosis MRPS7 mitochondrial ribosomal protein S7 10.39 10.05 -0.05 0.0 0.0 53.39 Detail
185 KIRC cuproptosis SOD1 superoxide dismutase 1 12.45 11.94 -0.06 0.0 0.0 53.29 Detail
186 KIRC cuproptosis RANGAP1 Ran GTPase activating protein 1 10.49 10.05 -0.06 0.0 0.0 52.94 Detail
187 KIRC cuproptosis SOD2 superoxide dismutase 2 13.23 14.28 0.11 0.0 0.0 52.88 Detail
188 KIRC cuproptosis COX7B cytochrome c oxidase subunit 7B 11.41 10.74 -0.09 0.0 0.0 52.83 Detail
189 KIRC cuproptosis NDUFB2 NADH:ubiquinone oxidoreductase subunit B2 10.93 10.34 -0.08 0.0 0.0 52.48 Detail
190 KIRC cuproptosis MFF mitochondrial fission factor 10.67 10.36 -0.04 0.0 0.0 52.45 Detail
191 KIRC cuproptosis MRPS30 mitochondrial ribosomal protein S30 8.85 8.54 -0.05 0.0 0.0 52.27 Detail
192 KIRC cuproptosis RPL27 ribosomal protein L27 12.12 12.81 0.08 0.0 0.0 52.21 Detail
193 KIRC cuproptosis NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 10.79 10.31 -0.07 0.0 0.0 52.2 Detail
194 KIRC cuproptosis GCSH glycine cleavage system protein H 5.83 4.67 -0.32 0.0 0.0 52.07 Detail
195 KIRC cuproptosis PARS2 prolyl-tRNA synthetase 2, mitochondrial 7.51 7.01 -0.1 0.0 0.0 52.03 Detail
196 KIRC cuproptosis SSBP1 single stranded DNA binding protein 1 9.68 10.14 0.07 0.0 0.0 52.02 Detail
197 KIRC cuproptosis MT1X metallothionein 1X 10.78 8.74 -0.3 0.0 0.0 51.91 Detail
198 KIRC cuproptosis SNCA synuclein alpha 7.19 6.03 -0.25 0.0 0.0 51.76 Detail
199 KIRC cuproptosis AFG3L2 AFG3 like matrix AAA peptidase subunit 2 11.38 10.85 -0.07 0.0 0.0 51.64 Detail
200 KIRC cuproptosis KIDINS220 kinase D interacting substrate 220 11.49 11.0 -0.06 0.0 0.0 51.64 Detail
201 KIRC cuproptosis RPAIN RPA interacting protein 8.53 8.96 0.07 0.0 0.0 51.56 Detail
202 KIRC cuproptosis MT1M metallothionein 1M 6.49 4.53 -0.52 0.0 0.0 51.45 Detail
203 KIRC cuproptosis NFKBIA NFKB inhibitor alpha 11.11 11.73 0.08 0.0 0.0 51.3 Detail
204 KIRC cuproptosis BCL2 BCL2 apoptosis regulator 10.31 10.92 0.08 0.0 0.0 50.82 Detail
205 KIRC cuproptosis YAP1 Yes1 associated transcriptional regulator 11.72 11.27 -0.06 0.0 0.0 50.67 Detail
206 KIRC cuproptosis CCL20 C-C motif chemokine ligand 20 4.57 7.11 0.64 0.0 0.0 50.01 Detail
207 KIRC cuproptosis UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 8.53 8.1 -0.07 0.0 0.0 49.65 Detail
208 KIRC cuproptosis CENPW centromere protein W 4.26 5.3 0.31 0.0 0.0 49.57 Detail
209 KIRC cuproptosis ACO2 aconitase 2 12.86 12.26 -0.07 0.0 0.0 49.25 Detail
210 KIRC cuproptosis ACTR10 actin related protein 10 10.23 9.86 -0.05 0.0 0.0 49.07 Detail
211 KIRC cuproptosis GFRA3 GDNF family receptor alpha 3 2.89 1.11 -1.38 0.0 0.0 48.97 Detail
212 KIRC cuproptosis MARS2 methionyl-tRNA synthetase 2, mitochondrial 7.73 7.24 -0.09 0.0 0.0 48.83 Detail
213 KIRC cuproptosis COX19 cytochrome c oxidase assembly factor COX19 7.38 7.9 0.1 0.0 0.0 48.33 Detail
214 KIRC cuproptosis MRPL17 mitochondrial ribosomal protein L17 9.67 10.14 0.07 0.0 0.0 48.04 Detail
215 KIRC cuproptosis MDH2 malate dehydrogenase 2 11.94 11.52 -0.05 0.0 0.0 47.86 Detail
216 KIRC cuproptosis COQ2 coenzyme Q2, polyprenyltransferase 7.49 6.98 -0.1 0.0 0.0 47.83 Detail
217 KIRC cuproptosis EGLN1 egl-9 family hypoxia inducible factor 1 11.14 11.5 0.05 0.0 0.0 47.56 Detail
218 KIRC cuproptosis RIPK1 receptor interacting serine/threonine kinase 1 9.92 10.18 0.04 0.0 0.0 47.47 Detail
219 KIRC cuproptosis PURG purine rich element binding protein G 3.61 2.8 -0.37 0.0 0.0 47.34 Detail
220 KIRC cuproptosis MRPS5 mitochondrial ribosomal protein S5 10.09 9.81 -0.04 0.0 0.0 46.66 Detail
221 KIRC cuproptosis COQ7 coenzyme Q7, hydroxylase 9.21 8.94 -0.04 0.0 0.0 46.62 Detail
222 KIRC cuproptosis MUC20 mucin 20, cell surface associated 10.63 9.24 -0.2 0.0 0.0 46.38 Detail
223 KIRC cuproptosis CIAO1 cytosolic iron-sulfur assembly component 1 11.15 10.95 -0.03 0.0 0.0 46.3 Detail
224 KIRC cuproptosis RUVBL2 RuvB like AAA ATPase 2 10.03 10.46 0.06 0.0 0.0 46.11 Detail
225 KIRC cuproptosis RB1 RB transcriptional corepressor 1 10.64 11.0 0.05 0.0 0.0 45.78 Detail
226 KIRC cuproptosis CDK1 cyclin dependent kinase 1 6.57 7.33 0.16 0.0 0.0 45.33 Detail
227 KIRC cuproptosis PRKDC protein kinase, DNA-activated, catalytic subunit 11.65 11.09 -0.07 0.0 0.0 45.29 Detail
228 KIRC cuproptosis NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase 10.27 9.94 -0.05 0.0 0.0 45.12 Detail
229 KIRC cuproptosis RPUSD3 RNA pseudouridine synthase D3 8.47 8.06 -0.07 0.0 0.0 44.98 Detail
230 KIRC cuproptosis PDE3B phosphodiesterase 3B 7.55 6.5 -0.22 0.0 0.0 44.91 Detail
231 KIRC cuproptosis PSMA6 proteasome 20S subunit alpha 6 10.42 10.76 0.05 0.0 0.0 43.39 Detail
232 KIRC cuproptosis CAPRIN1 cell cycle associated protein 1 12.48 12.17 -0.04 0.0 0.0 43.19 Detail
233 KIRC cuproptosis MT1E metallothionein 1E 10.53 8.8 -0.26 0.0 0.0 43.07 Detail
234 KIRC cuproptosis NUP133 nucleoporin 133 10.13 9.8 -0.05 0.0 0.0 43.04 Detail
235 KIRC cuproptosis DBH dopamine beta-hydroxylase 4.26 3.2 -0.41 0.0 0.0 42.97 Detail
236 KIRC cuproptosis TANK TRAF family member associated NFKB activator 9.34 9.62 0.04 0.0 0.0 42.97 Detail
237 KIRC cuproptosis RPUSD4 RNA pseudouridine synthase D4 8.5 8.86 0.06 0.0 0.0 42.83 Detail
238 KIRC cuproptosis SCO2 synthesis of cytochrome C oxidase 2 8.29 8.96 0.11 0.0 0.0 42.79 Detail
239 KIRC cuproptosis ANKRD49 ankyrin repeat domain 49 7.6 7.99 0.07 0.0 0.0 42.78 Detail
240 KIRC cuproptosis STEAP2 STEAP2 metalloreductase 9.28 8.3 -0.16 0.0 0.0 42.12 Detail
241 KIRC cuproptosis CYC1 cytochrome c1 11.55 11.06 -0.06 0.0 0.0 41.65 Detail
242 KIRC cuproptosis HSCB HscB mitochondrial iron-sulfur cluster cochaperone 7.53 7.94 0.08 0.0 0.0 41.56 Detail
243 KIRC cuproptosis MCAT malonyl-CoA-acyl carrier protein transacylase 8.82 8.38 -0.07 0.0 0.0 41.52 Detail
244 KIRC cuproptosis SERPINE1 serpin family E member 1 10.21 11.93 0.22 0.0 0.0 41.49 Detail
245 KIRC cuproptosis INSL4 insulin like 4 0.67 0.08 -2.99 0.0 0.0 41.42 Detail
246 KIRC cuproptosis OXA1L OXA1L mitochondrial inner membrane protein 10.94 11.26 0.04 0.0 0.0 41.38 Detail
247 KIRC cuproptosis TRAIP TRAF interacting protein 4.13 4.8 0.22 0.0 0.0 40.16 Detail
248 KIRC cuproptosis C7orf26 integrator complex subunit 15 8.62 8.88 0.04 0.0 0.0 39.88 Detail
249 KIRC cuproptosis PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.25 9.99 -0.04 0.0 0.0 39.87 Detail
250 KIRC cuproptosis NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 9.85 9.49 -0.05 0.0 0.0 39.76 Detail
251 KIRC cuproptosis ABCB8 ATP binding cassette subfamily B member 8 9.36 8.94 -0.06 0.0 0.0 39.56 Detail
252 KIRC cuproptosis POLR2B RNA polymerase II subunit B 10.9 10.67 -0.03 0.0 0.0 39.25 Detail
253 KIRC cuproptosis ABCB4 ATP binding cassette subfamily B member 4 4.9 6.23 0.34 0.0 0.0 39.04 Detail
254 KIRC cuproptosis CIAPIN1 cytokine induced apoptosis inhibitor 1 9.92 9.67 -0.04 0.0 0.0 39.02 Detail
255 KIRC cuproptosis MAP1LC3A microtubule associated protein 1 light chain 3 alpha 8.65 8.11 -0.09 0.0 0.0 38.95 Detail
256 KIRC cuproptosis SYMPK symplekin scaffold protein 10.34 10.6 0.04 0.0 0.0 38.56 Detail
257 KIRC cuproptosis MRPL13 mitochondrial ribosomal protein L13 9.38 9.04 -0.05 0.0 0.0 38.17 Detail
258 KIRC cuproptosis MRPL16 mitochondrial ribosomal protein L16 9.84 9.51 -0.05 0.0 0.0 37.46 Detail
259 KIRC cuproptosis SPDYE1 speedy/RINGO cell cycle regulator family member E1 2.64 3.45 0.39 0.0 0.0 37.37 Detail
260 KIRC cuproptosis MADD MAP kinase activating death domain 10.41 10.08 -0.05 0.0 0.0 37.25 Detail
261 KIRC cuproptosis MTF1 metal regulatory transcription factor 1 9.17 8.77 -0.06 0.0 0.0 35.83 Detail
262 KIRC cuproptosis POLR2K RNA polymerase II, I and III subunit K 9.82 9.55 -0.04 0.0 0.0 34.95 Detail
263 KIRC cuproptosis C1QBP complement C1q binding protein 10.55 10.23 -0.04 0.0 0.0 34.91 Detail
264 KIRC cuproptosis IMP4 IMP U3 small nucleolar ribonucleoprotein 4 8.99 9.3 0.05 0.0 0.0 34.54 Detail
265 KIRC cuproptosis TSC22D2 TSC22 domain family member 2 9.49 9.02 -0.07 0.0 0.0 34.42 Detail
266 KIRC cuproptosis HSF1 heat shock transcription factor 1 10.05 10.38 0.05 0.0 0.0 33.43 Detail
267 KIRC cuproptosis SP1 Sp1 transcription factor 11.45 11.7 0.03 0.0 0.0 33.43 Detail
268 KIRC cuproptosis COX15 cytochrome c oxidase assembly homolog COX15 10.58 10.33 -0.03 0.0 0.0 33.31 Detail
269 KIRC cuproptosis N6AMT1 N-6 adenine-specific DNA methyltransferase 1 8.12 7.8 -0.06 0.0 0.0 33.01 Detail
270 KIRC cuproptosis MRPL2 mitochondrial ribosomal protein L2 9.22 8.95 -0.04 0.0 0.0 32.98 Detail
271 KIRC cuproptosis DLG3 discs large MAGUK scaffold protein 3 10.11 9.66 -0.07 0.0 0.0 32.83 Detail
272 KIRC cuproptosis PPIE peptidylprolyl isomerase E 9.33 9.58 0.04 0.0 0.0 32.32 Detail
273 KIRC cuproptosis TAF6L TATA-box binding protein associated factor 6 like 8.03 7.74 -0.05 0.0 0.0 32.27 Detail
274 KIRC cuproptosis MRPL51 mitochondrial ribosomal protein L51 10.23 10.53 0.04 0.0 0.0 32.21 Detail
275 KIRC cuproptosis GGPS1 geranylgeranyl diphosphate synthase 1 9.57 9.4 -0.03 0.0 0.0 31.48 Detail
276 KIRC cuproptosis ZNF341 zinc finger protein 341 6.1 6.46 0.08 0.0 0.0 31.42 Detail
277 KIRC cuproptosis UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 10.56 10.22 -0.05 0.0 0.0 31.32 Detail
278 KIRC cuproptosis IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma 10.28 10.02 -0.04 0.0 0.0 31.2 Detail
279 KIRC cuproptosis MRPL41 mitochondrial ribosomal protein L41 9.3 8.71 -0.09 0.0 0.0 31.17 Detail
280 KIRC cuproptosis BACE1 beta-secretase 1 10.47 10.19 -0.04 0.0 0.0 31.15 Detail
281 KIRC cuproptosis SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit 11.2 10.92 -0.04 0.0 0.0 31.03 Detail
282 KIRC cuproptosis PPP1R15A protein phosphatase 1 regulatory subunit 15A 10.29 10.94 0.09 0.0 0.0 30.88 Detail
283 KIRC cuproptosis PRNP prion protein (Kanno blood group) 11.61 11.21 -0.05 0.0 0.0 30.49 Detail
284 KIRC cuproptosis CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 8.99 8.67 -0.05 0.0 0.0 30.43 Detail
285 KIRC cuproptosis CCDC22 coiled-coil domain containing 22 8.63 8.85 0.04 0.0 0.0 30.35 Detail
286 KIRC cuproptosis CYP2D6 cytochrome P450 family 2 subfamily D member 6 1.81 2.99 0.72 0.0 0.0 30.22 Detail
287 KIRC cuproptosis SURF1 SURF1 cytochrome c oxidase assembly factor 9.91 9.56 -0.05 0.0 0.0 30.18 Detail
288 KIRC cuproptosis IDH1 isocitrate dehydrogenase (NADP(+)) 1 11.06 10.36 -0.1 0.0 0.0 29.98 Detail
289 KIRC cuproptosis MAN2C1 mannosidase alpha class 2C member 1 9.86 10.3 0.06 0.0 0.0 29.85 Detail
290 KIRC cuproptosis SEC14L2 SEC14 like lipid binding 2 7.84 8.39 0.1 0.0 0.0 29.12 Detail
291 KIRC cuproptosis NAPA NSF attachment protein alpha 11.49 11.29 -0.03 0.0 0.0 28.22 Detail
292 KIRC cuproptosis MRPL55 mitochondrial ribosomal protein L55 8.41 8.93 0.09 0.0 0.0 28.11 Detail
293 KIRC cuproptosis NRF1 nuclear respiratory factor 1 8.22 8.4 0.03 0.0 0.0 28.03 Detail
294 KIRC cuproptosis MRPS22 mitochondrial ribosomal protein S22 9.14 8.93 -0.03 0.0 0.0 27.98 Detail
295 KIRC cuproptosis MRPS18B mitochondrial ribosomal protein S18B 10.77 10.51 -0.04 0.0 0.0 27.94 Detail
296 KIRC cuproptosis STEAP4 STEAP4 metalloreductase 8.32 9.39 0.18 0.0 0.0 27.56 Detail
297 KIRC cuproptosis RHOV ras homolog family member V 5.8 4.52 -0.36 0.0 0.0 27.52 Detail
298 KIRC cuproptosis GNL3 G protein nucleolar 3 9.04 9.35 0.05 0.0 0.0 27.46 Detail
299 KIRC cuproptosis ATP6AP1 ATPase H+ transporting accessory protein 1 12.2 11.96 -0.03 0.0 0.0 26.8 Detail
300 KIRC cuproptosis ELP3 elongator acetyltransferase complex subunit 3 9.83 9.59 -0.04 0.0 0.0 26.79 Detail
301 KIRC cuproptosis WDR12 WD repeat domain 12 8.71 8.43 -0.05 0.0 0.0 26.32 Detail
302 KIRC cuproptosis FZD8 frizzled class receptor 8 8.83 8.43 -0.07 0.0 0.0 25.91 Detail
303 KIRC cuproptosis FADD Fas associated via death domain 8.88 9.17 0.05 0.0 0.0 25.82 Detail
304 KIRC cuproptosis SRP54 signal recognition particle 54 10.18 9.94 -0.03 0.0 0.0 25.79 Detail
305 KIRC cuproptosis ELF3 E74 like ETS transcription factor 3 11.35 10.38 -0.13 0.0 0.0 25.69 Detail
306 KIRC cuproptosis ZFAT zinc finger and AT-hook domain containing 9.15 8.65 -0.08 0.0 0.0 25.54 Detail
307 KIRC cuproptosis ULK1 unc-51 like autophagy activating kinase 1 9.77 10.17 0.06 0.0 0.0 25.45 Detail
308 KIRC cuproptosis MRPL44 mitochondrial ribosomal protein L44 9.79 9.5 -0.04 0.0 0.0 25.19 Detail
309 KIRC cuproptosis REXO2 RNA exonuclease 2 10.08 9.86 -0.03 0.0 0.0 24.73 Detail
310 KIRC cuproptosis CCS copper chaperone for superoxide dismutase 8.89 9.23 0.05 0.0 0.0 24.69 Detail
311 KIRC cuproptosis CISD1 CDGSH iron sulfur domain 1 9.99 9.67 -0.05 0.0 0.0 24.65 Detail
312 KIRC cuproptosis ATL2 atlastin GTPase 2 9.97 9.74 -0.03 0.0 0.0 24.39 Detail
313 KIRC cuproptosis SDHA succinate dehydrogenase complex flavoprotein subunit A 12.35 12.07 -0.03 0.0 0.0 23.75 Detail
314 KIRC cuproptosis GATC glutamyl-tRNA amidotransferase subunit C 5.49 4.94 -0.15 0.0 0.0 23.55 Detail
315 KIRC cuproptosis SLC25A19 solute carrier family 25 member 19 7.3 7.66 0.07 0.0 0.0 23.23 Detail
316 KIRC cuproptosis PCGF6 polycomb group ring finger 6 6.98 7.16 0.04 0.0 0.0 22.42 Detail
317 KIRC cuproptosis MRPL30 mitochondrial ribosomal protein L30 9.74 9.6 -0.02 0.0 0.0 22.33 Detail
318 KIRC cuproptosis BARX1 BARX homeobox 1 0.24 0.97 2.02 0.0 0.0 22.2 Detail
319 KIRC cuproptosis MTFR1 mitochondrial fission regulator 1 9.84 9.35 -0.07 0.0 0.0 21.98 Detail
320 KIRC cuproptosis NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 10.04 9.79 -0.04 0.0 0.0 21.97 Detail
321 KIRC cuproptosis CDC27 cell division cycle 27 10.24 10.41 0.02 0.0 0.0 21.69 Detail
322 KIRC cuproptosis HSPA9 heat shock protein family A (Hsp70) member 9 13.11 12.84 -0.03 0.0 0.0 21.57 Detail
323 KIRC cuproptosis MECR mitochondrial trans-2-enoyl-CoA reductase 8.49 8.29 -0.03 0.0 0.0 21.57 Detail
324 KIRC cuproptosis NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic 9.07 9.43 0.06 0.0 0.0 21.33 Detail
325 KIRC cuproptosis NDUFS6 NADH:ubiquinone oxidoreductase subunit S6 9.76 9.47 -0.04 0.0 0.0 21.3 Detail
326 KIRC cuproptosis BUD31 BUD31 homolog 9.73 10.08 0.05 0.0 0.0 20.99 Detail
327 KIRC cuproptosis DTYMK deoxythymidylate kinase 7.95 8.3 0.06 0.0 0.0 20.7 Detail
328 KIRC cuproptosis NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 11.08 10.8 -0.04 0.0 0.0 20.63 Detail
329 KIRC cuproptosis SOX2 SRY-box transcription factor 2 1.09 0.83 -0.38 0.0 0.0 20.55 Detail
330 KIRC cuproptosis COX7A1 cytochrome c oxidase subunit 7A1 8.58 7.98 -0.1 0.0 0.0 20.41 Detail
331 KIRC cuproptosis TIMM9 translocase of inner mitochondrial membrane 9 8.58 8.86 0.05 0.0 0.0 20.11 Detail
332 KIRC cuproptosis AOC2 amine oxidase copper containing 2 3.84 4.28 0.16 0.0 0.0 18.82 Detail
333 KIRC cuproptosis CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 9.46 9.71 0.04 0.0 0.0 18.73 Detail
334 KIRC cuproptosis NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic 9.01 9.17 0.03 0.0 0.0 18.44 Detail
335 KIRC cuproptosis PITRM1 pitrilysin metallopeptidase 1 10.74 10.52 -0.03 0.0 0.0 18.35 Detail
336 KIRC cuproptosis DIP2B disco interacting protein 2 homolog B 9.88 10.13 0.04 0.0 0.0 18.27 Detail
337 KIRC cuproptosis PSMB5 proteasome 20S subunit beta 5 10.81 10.62 -0.03 0.0 0.0 18.04 Detail
338 KIRC cuproptosis INTS6 integrator complex subunit 6 9.53 9.33 -0.03 0.0 0.0 17.94 Detail
339 KIRC cuproptosis MRPL14 mitochondrial ribosomal protein L14 8.79 9.09 0.05 0.0 0.0 17.46 Detail
340 KIRC cuproptosis NDUFA8 NADH:ubiquinone oxidoreductase subunit A8 9.93 9.74 -0.03 0.0 0.0 17.15 Detail
341 KIRC cuproptosis EIF3I eukaryotic translation initiation factor 3 subunit I 11.45 11.65 0.02 0.0 0.0 16.98 Detail
342 KIRC cuproptosis ATP7A ATPase copper transporting alpha 9.37 9.09 -0.04 0.0 0.0 16.06 Detail
343 KIRC cuproptosis MBTPS1 membrane bound transcription factor peptidase, site 1 11.59 11.42 -0.02 0.0 0.0 15.83 Detail
344 KIRC cuproptosis PGP phosphoglycolate phosphatase 8.13 7.87 -0.05 0.0 0.0 15.56 Detail
345 KIRC cuproptosis SPATA5 AFG2 AAA ATPase homolog A 7.69 7.45 -0.04 0.0 0.0 15.51 Detail
346 KIRC cuproptosis POT1 protection of telomeres 1 9.12 9.31 0.03 0.0 0.0 15.22 Detail
347 KIRC cuproptosis DPH1 diphthamide biosynthesis 1 9.27 9.47 0.03 0.0 0.0 15.15 Detail
348 KIRC cuproptosis FAM96A cytosolic iron-sulfur assembly component 2A 9.8 9.61 -0.03 0.0 0.0 15.02 Detail
349 KIRC cuproptosis HNRNPU heterogeneous nuclear ribonucleoprotein U 13.15 12.98 -0.02 0.0 0.0 14.97 Detail
350 KIRC cuproptosis HSPD1 heat shock protein family D (Hsp60) member 1 13.06 12.77 -0.03 0.0 0.0 14.88 Detail
351 KIRC cuproptosis COX6B1 cytochrome c oxidase subunit 6B1 11.63 11.41 -0.03 0.0 0.0 14.73 Detail
352 KIRC cuproptosis COX7C cytochrome c oxidase subunit 7C 12.29 12.05 -0.03 0.0 0.0 14.45 Detail
353 KIRC cuproptosis MMGT1 membrane magnesium transporter 1 10.18 9.89 -0.04 0.0 0.0 13.94 Detail
354 KIRC cuproptosis MRPS11 mitochondrial ribosomal protein S11 9.0 8.83 -0.03 0.0 0.0 13.78 Detail
355 KIRC cuproptosis ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 8.39 8.24 -0.03 0.0 0.0 13.44 Detail
356 KIRC cuproptosis MAP2K2 mitogen-activated protein kinase kinase 2 10.42 10.66 0.03 0.0 0.0 13.44 Detail
357 KIRC cuproptosis DHX15 DEAH-box helicase 15 11.2 11.01 -0.02 0.0 0.0 13.32 Detail
358 KIRC cuproptosis GPX4 glutathione peroxidase 4 11.48 11.86 0.05 0.0 0.0 12.58 Detail
359 KIRC cuproptosis MT3 metallothionein 3 4.63 5.91 0.35 0.0 0.0 12.53 Detail
360 KIRC cuproptosis TYR tyrosinase 0.3 0.68 1.19 0.0 0.0 12.48 Detail
361 KIRC cuproptosis NDOR1 NADPH dependent diflavin oxidoreductase 1 8.5 8.24 -0.05 0.0 0.0 12.46 Detail
362 KIRC cuproptosis DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 10.06 10.16 0.01 0.0 0.0 11.7 Detail
363 KIRC cuproptosis FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 8.17 8.01 -0.03 0.0 0.0 10.65 Detail
364 KIRC cuproptosis RAD23B RAD23 homolog B, nucleotide excision repair protein 11.63 11.49 -0.02 0.0 0.0 10.64 Detail
365 KIRC cuproptosis MTG1 mitochondrial ribosome associated GTPase 1 8.94 8.77 -0.03 0.0 0.0 10.42 Detail
366 KIRC cuproptosis CHMP4B charged multivesicular body protein 4B 11.35 11.52 0.02 0.0 0.0 10.04 Detail
367 KIRC cuproptosis GADD45GIP1 GADD45G interacting protein 1 9.33 9.72 0.06 0.0 0.0 10.03 Detail
368 KIRC cuproptosis MRPL52 mitochondrial ribosomal protein L52 8.97 8.78 -0.03 0.0 0.0 9.98 Detail
369 KIRC cuproptosis MRPS12 mitochondrial ribosomal protein S12 9.02 8.82 -0.03 0.0 0.0 9.85 Detail
370 KIRC cuproptosis SARS2 seryl-tRNA synthetase 2, mitochondrial 8.38 8.21 -0.03 0.0 0.0 8.68 Detail
371 KIRC cuproptosis DOT1L DOT1 like histone lysine methyltransferase 8.62 8.88 0.04 0.0 0.01 8.14 Detail
372 KIRC cuproptosis MRPS23 mitochondrial ribosomal protein S23 9.53 9.41 -0.02 0.0 0.01 7.54 Detail
373 KIRC cuproptosis HMBS hydroxymethylbilane synthase 8.12 7.92 -0.04 0.01 0.01 6.69 Detail
374 KIRC cuproptosis STK11 serine/threonine kinase 11 9.61 9.77 0.02 0.01 0.01 6.6 Detail
375 KIRC cuproptosis AOC3 amine oxidase copper containing 3 10.35 9.87 -0.07 0.01 0.01 6.41 Detail
376 KIRC cuproptosis ABCB10 ATP binding cassette subfamily B member 10 8.84 8.92 0.01 0.01 0.01 6.13 Detail
377 KIRC cuproptosis EIF4G1 eukaryotic translation initiation factor 4 gamma 1 12.64 12.49 -0.02 0.01 0.01 6.05 Detail
378 KIRC cuproptosis ATP7B ATPase copper transporting beta 8.34 8.51 0.03 0.01 0.01 6.01 Detail
379 KIRC cuproptosis SNAPIN SNAP associated protein 9.09 9.22 0.02 0.01 0.01 5.81 Detail
380 KIRC cuproptosis MRPL39 mitochondrial ribosomal protein L39 8.87 8.73 -0.02 0.01 0.01 5.59 Detail
381 KIRC cuproptosis SAMM50 SAMM50 sorting and assembly machinery component 10.13 10.0 -0.02 0.01 0.01 4.9 Detail
382 KIRC cuproptosis COX4I1 cytochrome c oxidase subunit 4I1 12.49 12.36 -0.01 0.01 0.01 4.86 Detail
383 KIRC cuproptosis MRPL12 mitochondrial ribosomal protein L12 9.79 9.63 -0.02 0.01 0.01 4.59 Detail
384 KIRC cuproptosis PCBP2 poly(rC) binding protein 2 13.73 13.61 -0.01 0.01 0.01 4.4 Detail
385 KIRC cuproptosis NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 10.87 10.73 -0.02 0.01 0.02 3.94 Detail
386 KIRC cuproptosis GTF2B general transcription factor IIB 8.95 8.84 -0.02 0.01 0.02 3.77 Detail
387 KIRC cuproptosis LACTB2 lactamase beta 2 9.56 9.23 -0.05 0.01 0.02 3.45 Detail
388 KIRC cuproptosis ABCE1 ATP binding cassette subfamily E member 1 10.15 10.26 0.01 0.01 0.02 3.23 Detail
389 KIRC cuproptosis MT1DP metallothionein 1D, pseudogene 1.55 2.08 0.42 0.01 0.02 3.16 Detail
390 KIRC cuproptosis NFYC nuclear transcription factor Y subunit gamma 10.06 9.95 -0.02 0.02 0.02 3.0 Detail
391 KIRC cuproptosis NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 10.5 10.36 -0.02 0.02 0.02 2.38 Detail
392 KIRC cuproptosis EARS2 glutamyl-tRNA synthetase 2, mitochondrial 9.43 9.32 -0.02 0.02 0.02 2.25 Detail
393 KIRC cuproptosis MPZL3 myelin protein zero like 3 4.86 4.41 -0.14 0.02 0.03 1.84 Detail
394 KIRC cuproptosis ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 10.37 10.23 -0.02 0.02 0.03 1.74 Detail
395 KIRC cuproptosis DDX20 DEAD-box helicase 20 8.44 8.54 0.02 0.02 0.03 1.46 Detail
396 KIRC cuproptosis COPZ1 COPI coat complex subunit zeta 1 11.61 11.77 0.02 0.02 0.03 1.36 Detail
397 KIRC cuproptosis SLC31A2 solute carrier family 31 member 2 8.88 9.17 0.05 0.02 0.03 1.16 Detail
398 KIRC cuproptosis VARS2 valyl-tRNA synthetase 2, mitochondrial 9.48 9.63 0.02 0.02 0.03 0.99 Detail
399 KIRC cuproptosis TAF4 TATA-box binding protein associated factor 4 8.35 8.46 0.02 0.03 0.03 0.48 Detail
400 KIRC cuproptosis AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 10.15 10.02 -0.02 0.03 0.04 0.15 Detail
401 KIRC cuproptosis SDHAF2 succinate dehydrogenase complex assembly factor 2 9.19 9.11 -0.01 0.03 0.04 0.14 Detail
402 KIRC cuproptosis CIT citron rho-interacting serine/threonine kinase 10.0 10.29 0.04 0.03 0.04 0.1 Detail
403 KIRC cuproptosis NDUFB11 NADH:ubiquinone oxidoreductase subunit B11 10.34 10.25 -0.01 0.03 0.04 0.09 Detail
404 KIRC cuproptosis PARK7 Parkinsonism associated deglycase 11.77 11.68 -0.01 0.03 0.04 0.06 Detail
405 KIRC cuproptosis ATOX1 antioxidant 1 copper chaperone 9.84 9.98 0.02 0.44 0.47 0.0 Detail
406 KIRC cuproptosis MT2A metallothionein 2A 11.42 11.11 -0.04 0.03 0.04 0.0 Detail
407 KIRC cuproptosis AOC1 amine oxidase copper containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
408 KIRC cuproptosis MT1A metallothionein 1A 3.78 3.7 -0.03 0.49 0.52 0.0 Detail
409 KIRC cuproptosis MT1B metallothionein 1B 0.02 0.02 0.07 0.38 0.42 0.0 Detail
410 KIRC cuproptosis MT1HL1 metallothionein 1H like 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
411 KIRC cuproptosis MT4 metallothionein 4 0.0 0.0 inf 0.54 0.58 0.0 Detail
412 KIRC cuproptosis COMMD1 copper metabolism domain containing 1 8.15 8.23 0.01 0.34 0.37 0.0 Detail
413 KIRC cuproptosis STEAP3 STEAP3 metalloreductase 8.51 8.84 0.05 0.34 0.38 0.0 Detail
414 KIRC cuproptosis COX17 cytochrome c oxidase copper chaperone COX17 8.97 8.92 -0.01 0.16 0.19 0.0 Detail
415 KIRC cuproptosis HEPH hephaestin 8.84 8.74 -0.02 0.64 0.67 0.0 Detail
416 KIRC cuproptosis HEPHL1 hephaestin like 1 1.97 1.48 -0.42 0.19 0.22 0.0 Detail
417 KIRC cuproptosis RIPK3 receptor interacting serine/threonine kinase 3 6.34 6.41 0.02 0.36 0.4 0.0 Detail
418 KIRC cuproptosis TNF tumor necrosis factor 3.57 3.76 0.08 0.38 0.42 0.0 Detail
419 KIRC cuproptosis LIAS lipoic acid synthetase 7.87 7.78 -0.02 0.14 0.16 0.0 Detail
420 KIRC cuproptosis LIPT1 lipoyltransferase 1 7.02 7.01 -0.0 0.81 0.84 0.0 Detail
421 KIRC cuproptosis ABCB11 ATP binding cassette subfamily B member 11 0.17 0.31 0.88 0.13 0.15 0.0 Detail
422 KIRC cuproptosis ABCB7 ATP binding cassette subfamily B member 7 8.83 8.91 0.01 0.06 0.07 0.0 Detail
423 KIRC cuproptosis ACP1 acid phosphatase 1 10.68 10.72 0.01 0.61 0.65 0.0 Detail
424 KIRC cuproptosis ADGRE5 adhesion G protein-coupled receptor E5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
425 KIRC cuproptosis AP1S1 adaptor related protein complex 1 subunit sigma 1 9.91 9.87 -0.01 0.42 0.46 0.0 Detail
426 KIRC cuproptosis ARFGEF1-DT ARFGEF1 divergent transcript 0.0 0.0 0.0 0.0 0.0 0.0 Detail
427 KIRC cuproptosis ARHGEF39 Rho guanine nucleotide exchange factor 39 0.0 0.0 0.0 0.0 0.0 0.0 Detail
428 KIRC cuproptosis ARMH3 armadillo like helical domain containing 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
429 KIRC cuproptosis ATP5PD ATP synthase peripheral stalk subunit d 0.0 0.0 0.0 0.0 0.0 0.0 Detail
430 KIRC cuproptosis ATP7BP1 ATPase copper transporting beta pseudogene 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
431 KIRC cuproptosis BCKDH protein phosphatase, Mg2+/Mn2+ dependent 1K 0.0 0.0 0.0 0.0 0.0 0.0 Detail
432 KIRC cuproptosis BRPF1 bromodomain and PHD finger containing 1 8.66 8.54 -0.02 0.06 0.07 0.0 Detail
433 KIRC cuproptosis C6ORF136 chromosome 6 open reading frame 136 0.0 0.0 0.0 0.0 0.0 0.0 Detail
434 KIRC cuproptosis CCDC115 coiled-coil domain containing 115 10.16 10.16 -0.0 0.58 0.61 0.0 Detail
435 KIRC cuproptosis CCDC28B coiled-coil domain containing 28B 5.84 6.13 0.07 0.1 0.12 0.0 Detail
436 KIRC cuproptosis CCL8 C-C motif chemokine ligand 8 5.34 5.33 -0.0 0.93 0.94 0.0 Detail
437 KIRC cuproptosis CD274 CD274 molecule 5.23 5.33 0.03 0.18 0.21 0.0 Detail
438 KIRC cuproptosis CDK5RAP1 CDK5 regulatory subunit associated protein 1 8.48 8.49 0.0 0.37 0.41 0.0 Detail
439 KIRC cuproptosis CEPT1 choline/ethanolamine phosphotransferase 1 9.49 9.48 -0.0 0.92 0.93 0.0 Detail
440 KIRC cuproptosis CERS2 ceramide synthase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
441 KIRC cuproptosis CERT1 ceramide transporter 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
442 KIRC cuproptosis CHTOP chromatin target of PRMT1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
443 KIRC cuproptosis CIAO2A cytosolic iron-sulfur assembly component 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
444 KIRC cuproptosis CIAO2B cytosolic iron-sulfur assembly component 2B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
445 KIRC cuproptosis CLEC11A C-type lectin domain containing 11A 7.34 7.39 0.01 0.8 0.82 0.0 Detail
446 KIRC cuproptosis CLUH clustered mitochondria homolog 0.0 0.0 0.0 0.0 0.0 0.0 Detail
447 KIRC cuproptosis CMPK1 cytidine/uridine monophosphate kinase 1 11.48 11.53 0.01 0.15 0.18 0.0 Detail
448 KIRC cuproptosis CNN1 calponin 1 8.45 8.57 0.02 0.37 0.41 0.0 Detail
449 KIRC cuproptosis COA5 cytochrome c oxidase assembly factor 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
450 KIRC cuproptosis COA6 cytochrome c oxidase assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
451 KIRC cuproptosis COAS unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
452 KIRC cuproptosis COPB2 COPI coat complex subunit beta 2 11.51 11.45 -0.01 0.08 0.1 0.0 Detail
453 KIRC cuproptosis copper鈥搝inc alloy (CZA) unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
454 KIRC cuproptosis COPS5 COP9 signalosome subunit 5 9.89 9.99 0.01 0.04 0.05 0.0 Detail
455 KIRC cuproptosis COX14 cytochrome c oxidase assembly factor COX14 0.0 0.0 0.0 0.0 0.0 0.0 Detail
456 KIRC cuproptosis COX23 coiled-coil-helix-coiled-coil-helix domain containing 7 0.0 0.0 0.0 0.0 0.0 0.0 Detail
457 KIRC cuproptosis CSTF3 cleavage stimulation factor subunit 3 8.82 8.84 0.0 0.72 0.75 0.0 Detail
458 KIRC cuproptosis CTR1 solute carrier family 31 member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
459 KIRC cuproptosis CTR2 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
460 KIRC cuproptosis DAPK2 death associated protein kinase 2 6.28 6.48 0.04 0.61 0.64 0.0 Detail
461 KIRC cuproptosis DARS1 aspartyl-tRNA synthetase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
462 KIRC cuproptosis DBR1 debranching RNA lariats 1 8.45 8.4 -0.01 0.91 0.92 0.0 Detail
463 KIRC cuproptosis DCYTB cytochrome b reductase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
464 KIRC cuproptosis DMT1 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
465 KIRC cuproptosis DPYD dihydropyrimidine dehydrogenase 9.43 9.26 -0.03 0.12 0.15 0.0 Detail
466 KIRC cuproptosis DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 11.48 11.45 -0.0 0.96 0.96 0.0 Detail
467 KIRC cuproptosis DYNLRB1 dynein light chain roadblock-type 1 11.21 11.32 0.01 0.46 0.5 0.0 Detail
468 KIRC cuproptosis EFCC1 EF-hand and coiled-coil domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
469 KIRC cuproptosis ELOB elongin B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
470 KIRC cuproptosis EMC6 ER membrane protein complex subunit 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
471 KIRC cuproptosis EPC2 enhancer of polycomb homolog 2 9.19 9.2 0.0 0.28 0.31 0.0 Detail
472 KIRC cuproptosis ERK1 mitogen-activated protein kinase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
473 KIRC cuproptosis FAK protein tyrosine kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
474 KIRC cuproptosis FDX2 ferredoxin 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
475 KIRC cuproptosis FOXD2-AS1 FOXD2 adjacent opposite strand RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
476 KIRC cuproptosis FPGS folylpolyglutamate synthase 9.25 9.26 0.0 0.71 0.74 0.0 Detail
477 KIRC cuproptosis GATB glutamyl-tRNA amidotransferase subunit B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
478 KIRC cuproptosis GCLC glutamate-cysteine ligase catalytic subunit 9.54 9.53 -0.0 0.84 0.86 0.0 Detail
479 KIRC cuproptosis GCLM glutamate-cysteine ligase modifier subunit 8.68 8.61 -0.01 0.88 0.89 0.0 Detail
480 KIRC cuproptosis GLS40 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
481 KIRC cuproptosis glycerophospholipid unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
482 KIRC cuproptosis GRX1 glutaredoxin 0.0 0.0 0.0 0.0 0.0 0.0 Detail
483 KIRC cuproptosis GSH unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
484 KIRC cuproptosis GSS glutathione synthetase 10.28 10.17 -0.02 0.04 0.05 0.0 Detail
485 KIRC cuproptosis GTPBP4 GTP binding protein 4 9.41 9.37 -0.01 0.33 0.37 0.0 Detail
486 KIRC cuproptosis GTPBP6 GTP binding protein 6 (putative) 0.0 0.0 0.0 0.0 0.0 0.0 Detail
487 KIRC cuproptosis H1-10-AS1 H1-10 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
488 KIRC cuproptosis H2AC6 H2A clustered histone 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
489 KIRC cuproptosis H2BC6-AS1 H2BC6 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
490 KIRC cuproptosis H3C1 H3 clustered histone 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
491 KIRC cuproptosis HARS2 histidyl-tRNA synthetase 2, mitochondrial 9.52 9.61 0.01 0.06 0.07 0.0 Detail
492 KIRC cuproptosis HIST1H3A H3 clustered histone 1 0.56 0.37 -0.6 0.04 0.05 0.0 Detail
493 KIRC cuproptosis HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 13.43 13.35 -0.01 0.1 0.12 0.0 Detail
494 KIRC cuproptosis HSP70 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
495 KIRC cuproptosis IBA57 iron-sulfur cluster assembly factor IBA57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
496 KIRC cuproptosis IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta 10.67 10.66 -0.0 0.19 0.22 0.0 Detail
497 KIRC cuproptosis IFT81 intraflagellar transport 81 8.26 8.22 -0.01 0.94 0.95 0.0 Detail
498 KIRC cuproptosis IL-8 C-X-C motif chemokine ligand 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
499 KIRC cuproptosis INKA1 inka box actin regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
500 KIRC cuproptosis IOP1 cytosolic iron-sulfur assembly component 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
501 KIRC cuproptosis ISCU2 iron-sulfur cluster assembly enzyme 0.0 0.0 0.0 0.0 0.0 0.0 Detail
502 KIRC cuproptosis ISD11 LYR motif containing 4 0.0 0.0 0.0 0.0 0.0 0.0 Detail
503 KIRC cuproptosis KAT8 lysine acetyltransferase 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
504 KIRC cuproptosis KMT2A lysine methyltransferase 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
505 KIRC cuproptosis LASTR lncRNA associated with SART3 regulation of splicing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
506 KIRC cuproptosis LINC02038 long intergenic non-protein coding RNA 2038 0.0 0.0 0.0 0.0 0.0 0.0 Detail
507 KIRC cuproptosis LINC02154 long intergenic non-protein coding RNA 2154 0.0 0.0 0.0 0.0 0.0 0.0 Detail
508 KIRC cuproptosis LINC03085 long intergenic non-protein coding RNA 3085 0.0 0.0 0.0 0.0 0.0 0.0 Detail
509 KIRC cuproptosis LIPT2 lipoyl(octanoyl) transferase 2 5.21 5.27 0.02 0.65 0.68 0.0 Detail
510 KIRC cuproptosis LONP1 lon peptidase 1, mitochondrial 10.82 10.96 0.02 0.1 0.12 0.0 Detail
511 KIRC cuproptosis MAD2L2 mitotic arrest deficient 2 like 2 8.17 8.29 0.02 0.4 0.44 0.0 Detail
512 KIRC cuproptosis MAP2K1 mitogen-activated protein kinase kinase 1 10.5 10.54 0.01 0.18 0.21 0.0 Detail
513 KIRC cuproptosis MARCHF5 membrane associated ring-CH-type finger 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
514 KIRC cuproptosis MAU2 MAU2 sister chromatid cohesion factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
515 KIRC cuproptosis MBTPS2 membrane bound transcription factor peptidase, site 2 9.35 9.39 0.01 0.16 0.18 0.0 Detail
516 KIRC cuproptosis MCMBP minichromosome maintenance complex binding protein 0.0 0.0 0.0 0.0 0.0 0.0 Detail
517 KIRC cuproptosis MCUR1 mitochondrial calcium uniporter regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
518 KIRC cuproptosis MEK1 mitogen-activated protein kinase kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
519 KIRC cuproptosis MEK2 mitogen-activated protein kinase kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
520 KIRC cuproptosis METTL17 methyltransferase like 17 0.0 0.0 0.0 0.0 0.0 0.0 Detail
521 KIRC cuproptosis MPC1 mitochondrial pyruvate carrier 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
522 KIRC cuproptosis MRM2 mitochondrial rRNA methyltransferase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
523 KIRC cuproptosis MRPL21 mitochondrial ribosomal protein L21 8.94 9.04 0.01 0.24 0.28 0.0 Detail
524 KIRC cuproptosis MRPL36 mitochondrial ribosomal protein L36 8.2 8.24 0.01 0.98 0.98 0.0 Detail
525 KIRC cuproptosis MRPL40 mitochondrial ribosomal protein L40 9.52 9.68 0.02 0.23 0.26 0.0 Detail
526 KIRC cuproptosis MRPL53 mitochondrial ribosomal protein L53 8.81 8.99 0.03 0.04 0.05 0.0 Detail
527 KIRC cuproptosis MRPL57 mitochondrial ribosomal protein L57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
528 KIRC cuproptosis MRPS18A mitochondrial ribosomal protein S18A 9.37 9.34 -0.0 0.25 0.29 0.0 Detail
529 KIRC cuproptosis MRPS18C mitochondrial ribosomal protein S18C 8.2 8.17 -0.01 0.5 0.53 0.0 Detail
530 KIRC cuproptosis MRPS21 mitochondrial ribosomal protein S21 9.67 9.77 0.01 0.68 0.71 0.0 Detail
531 KIRC cuproptosis MRPS2 mitochondrial ribosomal protein S2 9.88 9.79 -0.01 0.09 0.11 0.0 Detail
532 KIRC cuproptosis MRPS33 mitochondrial ribosomal protein S33 9.35 9.31 -0.01 0.22 0.25 0.0 Detail
533 KIRC cuproptosis MRRF mitochondrial ribosome recycling factor 8.93 8.98 0.01 0.46 0.5 0.0 Detail
534 KIRC cuproptosis MT1 metallothionein 1A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
535 KIRC cuproptosis MT2 metallothionein 1B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
536 KIRC cuproptosis MT3A unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
537 KIRC cuproptosis MT-CO1 mitochondrially encoded cytochrome c oxidase I 0.0 0.0 0.0 0.0 0.0 0.0 Detail
538 KIRC cuproptosis MT-CO2 mitochondrially encoded cytochrome c oxidase II 0.0 0.0 0.0 0.0 0.0 0.0 Detail
539 KIRC cuproptosis MTCO2P12 MT-CO2 pseudogene 12 0.0 0.0 0.0 0.0 0.0 0.0 Detail
540 KIRC cuproptosis MT-CO3 mitochondrially encoded cytochrome c oxidase III 0.0 0.0 0.0 0.0 0.0 0.0 Detail
541 KIRC cuproptosis MT unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
542 KIRC cuproptosis MTERF1 mitochondrial transcription termination factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
543 KIRC cuproptosis MTFR1L mitochondrial fission regulator 1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
544 KIRC cuproptosis MTIF3 mitochondrial translational initiation factor 3 9.7 9.74 0.01 0.9 0.91 0.0 Detail
545 KIRC cuproptosis mTOR mechanistic target of rapamycin kinase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
546 KIRC cuproptosis MYO1B myosin IB 11.24 11.29 0.01 0.32 0.36 0.0 Detail
547 KIRC cuproptosis NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
548 KIRC cuproptosis NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 10.6 10.63 0.0 0.45 0.48 0.0 Detail
549 KIRC cuproptosis NDUFB4 NADH:ubiquinone oxidoreductase subunit B4 10.84 10.88 0.01 1.0 1.0 0.0 Detail
550 KIRC cuproptosis NDUFB7 NADH:ubiquinone oxidoreductase subunit B7 10.37 10.28 -0.01 0.08 0.1 0.0 Detail
551 KIRC cuproptosis NDUFC1 NADH:ubiquinone oxidoreductase subunit C1 10.2 10.29 0.01 0.47 0.5 0.0 Detail
552 KIRC cuproptosis NFU1 NFU1 iron-sulfur cluster scaffold 9.43 9.43 0.0 0.82 0.84 0.0 Detail
553 KIRC cuproptosis NNAT neuronatin 2.84 2.66 -0.1 0.29 0.33 0.0 Detail
554 KIRC cuproptosis NPL4 NPL4 homolog, ubiquitin recognition factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
555 KIRC cuproptosis NTHL1 nth like DNA glycosylase 1 7.13 7.25 0.02 0.36 0.4 0.0 Detail
556 KIRC cuproptosis P3H3 prolyl 3-hydroxylase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
557 KIRC cuproptosis p53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
558 KIRC cuproptosis P53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
559 KIRC cuproptosis p97 eukaryotic translation initiation factor 4 gamma 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
560 KIRC cuproptosis PDHA pyruvate dehydrogenase E1 subunit alpha 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
561 KIRC cuproptosis PDH pyruvate dehydrogenase phosphatase catalytic subunit 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
562 KIRC cuproptosis PDZD4 PDZ domain containing 4 5.6 5.88 0.07 0.1 0.12 0.0 Detail
563 KIRC cuproptosis PET100 PET100 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
564 KIRC cuproptosis PET117 PET117 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
565 KIRC cuproptosis PHF5A PHD finger protein 5A 8.49 8.58 0.01 0.06 0.08 0.0 Detail
566 KIRC cuproptosis PHOB unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
567 KIRC cuproptosis PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.0 0.0 0.0 0.0 0.0 0.0 Detail
568 KIRC cuproptosis PMVK phosphomevalonate kinase 10.02 10.11 0.01 0.43 0.46 0.0 Detail
569 KIRC cuproptosis PPAT phosphoribosyl pyrophosphate amidotransferase 8.05 8.1 0.01 0.22 0.26 0.0 Detail
570 KIRC cuproptosis PRDM10 PR/SET domain 10 7.74 7.66 -0.02 0.33 0.37 0.0 Detail
571 KIRC cuproptosis RANTES C-C motif chemokine ligand 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
572 KIRC cuproptosis RCC1L RCC1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
573 KIRC cuproptosis RMND1 required for meiotic nuclear division 1 homolog 9.13 9.18 0.01 0.77 0.8 0.0 Detail
574 KIRC cuproptosis RPAP1 RNA polymerase II associated protein 1 8.92 8.99 0.01 0.11 0.13 0.0 Detail
575 KIRC cuproptosis RRN3 RRN3 homolog, RNA polymerase I transcription factor 10.05 10.12 0.01 0.08 0.09 0.0 Detail
576 KIRC cuproptosis S6K1 ribosomal protein S6 kinase B1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
577 KIRC cuproptosis SEPTIN1 septin 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
578 KIRC cuproptosis SERPIND1 serpin family D member 1 1.87 1.74 -0.1 0.11 0.13 0.0 Detail
579 KIRC cuproptosis SGF29 SAGA complex associated factor 29 0.0 0.0 0.0 0.0 0.0 0.0 Detail
580 KIRC cuproptosis SLC25A32 solute carrier family 25 member 32 8.78 8.86 0.01 0.09 0.1 0.0 Detail
581 KIRC cuproptosis SLC25A51 solute carrier family 25 member 51 0.0 0.0 0.0 0.0 0.0 0.0 Detail
582 KIRC cuproptosis SLC30A10 solute carrier family 30 member 10 0.57 1.2 1.08 0.47 0.51 0.0 Detail
583 KIRC cuproptosis SLC33A1 solute carrier family 33 member 1 9.53 9.59 0.01 0.29 0.33 0.0 Detail
584 KIRC cuproptosis SLC52A2 solute carrier family 52 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
585 KIRC cuproptosis SLC7A5 solute carrier family 7 member 5 9.55 9.64 0.01 0.65 0.68 0.0 Detail
586 KIRC cuproptosis SMAD3-AS1 SMAD3 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
587 KIRC cuproptosis sp1 Sp1 transcription factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
588 KIRC cuproptosis STEAP4 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
589 KIRC cuproptosis STEAP STEAP family member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
590 KIRC cuproptosis SURF6 surfeit 6 9.12 9.07 -0.01 0.37 0.41 0.0 Detail
591 KIRC cuproptosis TADA2A transcriptional adaptor 2A 7.0 6.97 -0.01 0.94 0.95 0.0 Detail
592 KIRC cuproptosis TARS2 threonyl-tRNA synthetase 2, mitochondrial 9.07 9.04 -0.0 0.56 0.6 0.0 Detail
593 KIRC cuproptosis TEDC1 tubulin epsilon and delta complex 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
594 KIRC cuproptosis TEFM transcription elongation factor, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 Detail
595 KIRC cuproptosis TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
596 KIRC cuproptosis TKT transketolase 11.2 11.23 0.0 0.88 0.89 0.0 Detail
597 KIRC cuproptosis TMEM191B transmembrane protein 191B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
598 KIRC cuproptosis TRAPPC11 trafficking protein particle complex subunit 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
599 KIRC cuproptosis TRIM32 tripartite motif containing 32 8.58 8.51 -0.01 0.48 0.51 0.0 Detail
600 KIRC cuproptosis TRRAP transformation/transcription domain associated protein 10.75 10.65 -0.01 0.28 0.32 0.0 Detail
601 KIRC cuproptosis TUBGCP4 tubulin gamma complex component 4 8.08 7.92 -0.03 0.24 0.27 0.0 Detail
602 KIRC cuproptosis TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 8.99 9.06 0.01 0.22 0.26 0.0 Detail
603 KIRC cuproptosis TWNK twinkle mtDNA helicase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
604 KIRC cuproptosis U2SURP U2 snRNP associated SURP domain containing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
605 KIRC cuproptosis UBAP2L ubiquitin associated protein 2 like 11.18 11.25 0.01 0.04 0.05 0.0 Detail
606 KIRC cuproptosis UBE2D1 ubiquitin conjugating enzyme E2 D1 8.5 8.5 0.0 0.49 0.52 0.0 Detail
607 KIRC cuproptosis UBE2D3 ubiquitin conjugating enzyme E2 D3 12.51 12.47 -0.01 0.27 0.3 0.0 Detail
608 KIRC cuproptosis UlK1 unc-51 like autophagy activating kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
609 KIRC cuproptosis ULK2 unc-51 like autophagy activating kinase 2 9.24 9.11 -0.02 0.11 0.13 0.0 Detail
610 KIRC cuproptosis UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
611 KIRC cuproptosis UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
612 KIRC cuproptosis UTP25 UTP25 small subunit processome component 0.0 0.0 0.0 0.0 0.0 0.0 Detail
613 KIRC cuproptosis WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 8.78 8.71 -0.01 0.36 0.39 0.0 Detail
614 KIRC cuproptosis xCT solute carrier family 7 member 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
615 KIRC cuproptosis XRN1 5'-3' exoribonuclease 1 10.05 10.05 0.0 0.66 0.69 0.0 Detail
616 KIRC cuproptosis YAE1 YAE1 maturation factor of ABCE1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
617 KIRC cuproptosis YARS2 tyrosyl-tRNA synthetase 2 7.96 8.08 0.02 0.09 0.11 0.0 Detail
618 KIRC cuproptosis ZBTB11 zinc finger and BTB domain containing 11 9.15 9.16 0.0 0.99 0.99 0.0 Detail
619 KIRC cuproptosis ZKSCAN5 zinc finger with KRAB and SCAN domains 5 8.54 8.51 -0.0 0.27 0.31 0.0 Detail
620 KIRC cuproptosis ZNF365 zinc finger protein 365 4.23 4.42 0.06 0.75 0.78 0.0 Detail

Ensemble learning for KIRC based on specific cuproptosis gene regulaors.