Disease associated with RCD disease & gene list




LIHC specific anoikis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 LIHC anoikis E2F1 E2F transcription factor 1 4.94 8.49 0.78 0.0 0.0 100.0 Detail
2 LIHC anoikis PDK4 pyruvate dehydrogenase kinase 4 13.15 10.87 -0.27 0.0 0.0 71.73 Detail
3 LIHC anoikis DAPK2 death associated protein kinase 2 6.37 7.87 0.31 0.0 0.0 69.43 Detail
4 LIHC anoikis SIK1 salt inducible kinase 1 12.73 11.05 -0.2 0.0 0.0 65.48 Detail
5 LIHC anoikis PTK2 protein tyrosine kinase 2 10.21 10.88 0.09 0.0 0.0 64.9 Detail
6 LIHC anoikis MCL1 MCL1 apoptosis regulator, BCL2 family member 13.94 12.99 -0.1 0.0 0.0 62.41 Detail
7 LIHC anoikis BRMS1 BRMS1 transcriptional repressor and anoikis regulator 9.48 10.17 0.1 0.0 0.0 61.04 Detail
8 LIHC anoikis CHEK2 checkpoint kinase 2 6.57 7.77 0.24 0.0 0.0 53.87 Detail
9 LIHC anoikis TSC2 TSC complex subunit 2 10.12 10.56 0.06 0.0 0.0 52.01 Detail
10 LIHC anoikis NTRK2 neurotrophic receptor tyrosine kinase 2 6.05 3.96 -0.61 0.0 0.0 51.17 Detail
11 LIHC anoikis SRC SRC proto-oncogene, non-receptor tyrosine kinase 8.45 9.26 0.13 0.0 0.0 30.07 Detail
12 LIHC anoikis PTRH2 peptidyl-tRNA hydrolase 2 8.91 9.38 0.08 0.0 0.0 28.96 Detail
13 LIHC anoikis IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 9.38 9.98 0.09 0.0 0.0 28.72 Detail
14 LIHC anoikis ITGA5 integrin subunit alpha 5 11.09 11.54 0.06 0.0 0.0 28.09 Detail
15 LIHC anoikis TLE1 TLE family member 1, transcriptional corepressor 10.83 11.11 0.04 0.0 0.0 21.61 Detail
16 LIHC anoikis PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 8.12 7.74 -0.07 0.0 0.0 16.25 Detail
17 LIHC anoikis MYBBP1A MYB binding protein 1a 9.42 9.73 0.05 0.0 0.0 15.42 Detail
18 LIHC anoikis STK11 serine/threonine kinase 11 10.19 10.37 0.03 0.0 0.01 11.12 Detail
19 LIHC anoikis ANKRD13C ankyrin repeat domain 13C 8.54 8.38 -0.03 0.03 0.05 0.0 Detail
20 LIHC anoikis BCL2 BCL2 apoptosis regulator 7.09 6.8 -0.06 0.1 0.14 0.0 Detail
21 LIHC anoikis BCL2L1 BCL2 like 1 11.61 11.71 0.01 0.53 0.55 0.0 Detail
22 LIHC anoikis BMF Bcl2 modifying factor 7.78 8.31 0.09 0.04 0.06 0.0 Detail
23 LIHC anoikis CAV1 caveolin 1 9.51 9.67 0.03 0.25 0.3 0.0 Detail
24 LIHC anoikis CRYBA1 crystallin beta A1 0.14 0.18 0.36 0.33 0.38 0.0 Detail
25 LIHC anoikis ITGB1 integrin subunit beta 1 13.15 13.32 0.02 0.05 0.07 0.0 Detail
26 LIHC anoikis MAP3K7 mitogen-activated protein kinase kinase kinase 7 8.63 8.66 0.01 0.52 0.55 0.0 Detail
27 LIHC anoikis NOTCH1 notch receptor 1 9.38 9.38 -0.0 0.86 0.86 0.0 Detail
28 LIHC anoikis SNAI2 snail family transcriptional repressor 2 7.26 7.61 0.07 0.14 0.18 0.0 Detail
29 LIHC anoikis TFDP1 transcription factor Dp-1 9.77 9.76 -0.0 0.5 0.55 0.0 Detail

Ensemble learning for LIHC based on specific anoikis gene regulaors.