Disease associated with RCD disease & gene list




LIHC specific cuproptosis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 LIHC cuproptosis VPS45 vacuolar protein sorting 45 homolog 8.47 9.64 0.19 0.0 0.0 100.0 Detail
2 LIHC cuproptosis CDKN3 cyclin dependent kinase inhibitor 3 3.06 7.2 1.23 0.0 0.0 97.37 Detail
3 LIHC cuproptosis DBH dopamine beta-hydroxylase 10.09 5.39 -0.9 0.0 0.0 96.55 Detail
4 LIHC cuproptosis PRC1 protein regulator of cytokinesis 1 5.47 8.71 0.67 0.0 0.0 96.28 Detail
5 LIHC cuproptosis ETFDH electron transfer flavoprotein dehydrogenase 12.03 10.09 -0.25 0.0 0.0 95.78 Detail
6 LIHC cuproptosis TRAIP TRAF interacting protein 3.08 6.13 1.0 0.0 0.0 94.58 Detail
7 LIHC cuproptosis CDK1 cyclin dependent kinase 1 4.71 8.18 0.8 0.0 0.0 94.51 Detail
8 LIHC cuproptosis FOXM1 forkhead box M1 5.04 8.65 0.78 0.0 0.0 93.87 Detail
9 LIHC cuproptosis MT1H metallothionein 1H 11.63 4.1 -1.51 0.0 0.0 93.64 Detail
10 LIHC cuproptosis MT1G metallothionein 1G 15.01 8.06 -0.9 0.0 0.0 93.24 Detail
11 LIHC cuproptosis MT1F metallothionein 1F 12.5 6.66 -0.91 0.0 0.0 92.5 Detail
12 LIHC cuproptosis MT1M metallothionein 1M 11.58 5.32 -1.12 0.0 0.0 92.32 Detail
13 LIHC cuproptosis ANLN anillin, actin binding protein 3.81 7.65 1.01 0.0 0.0 91.53 Detail
14 LIHC cuproptosis FXN frataxin 9.78 8.42 -0.22 0.0 0.0 91.15 Detail
15 LIHC cuproptosis CENPW centromere protein W 4.61 6.97 0.6 0.0 0.0 90.75 Detail
16 LIHC cuproptosis CDKN2A cyclin dependent kinase inhibitor 2A 3.75 7.8 1.06 0.0 0.0 90.1 Detail
17 LIHC cuproptosis ALB albumin 22.15 19.82 -0.16 0.0 0.0 89.91 Detail
18 LIHC cuproptosis MT1E metallothionein 1E 14.28 9.19 -0.64 0.0 0.0 89.78 Detail
19 LIHC cuproptosis MT2A metallothionein 2A 16.1 12.07 -0.42 0.0 0.0 89.24 Detail
20 LIHC cuproptosis MAP2K1 mitogen-activated protein kinase kinase 1 11.27 10.04 -0.17 0.0 0.0 88.81 Detail
21 LIHC cuproptosis HAUS5 HAUS augmin like complex subunit 5 7.43 8.47 0.19 0.0 0.0 88.7 Detail
22 LIHC cuproptosis ZNF341 zinc finger protein 341 6.01 7.12 0.24 0.0 0.0 88.54 Detail
23 LIHC cuproptosis STEAP3 STEAP3 metalloreductase 13.2 10.94 -0.27 0.0 0.0 88.53 Detail
24 LIHC cuproptosis UBAP2L ubiquitin associated protein 2 like 10.43 11.42 0.13 0.0 0.0 88.13 Detail
25 LIHC cuproptosis MT1X metallothionein 1X 14.49 9.96 -0.54 0.0 0.0 87.05 Detail
26 LIHC cuproptosis MTBP MDM2 binding protein 3.41 5.52 0.7 0.0 0.0 84.25 Detail
27 LIHC cuproptosis MYO1B myosin IB 13.69 12.33 -0.15 0.0 0.0 83.88 Detail
28 LIHC cuproptosis CP ceruloplasmin 16.49 14.28 -0.21 0.0 0.0 83.71 Detail
29 LIHC cuproptosis SNAPIN SNAP associated protein 8.89 9.61 0.11 0.0 0.0 83.39 Detail
30 LIHC cuproptosis CAT catalase 14.52 12.89 -0.17 0.0 0.0 83.36 Detail
31 LIHC cuproptosis MRPS23 mitochondrial ribosomal protein S23 8.89 9.74 0.13 0.0 0.0 83.31 Detail
32 LIHC cuproptosis STEAP4 STEAP4 metalloreductase 10.05 7.22 -0.48 0.0 0.0 83.22 Detail
33 LIHC cuproptosis SLC31A1 solute carrier family 31 member 1 12.56 11.42 -0.14 0.0 0.0 82.74 Detail
34 LIHC cuproptosis ZKSCAN5 zinc finger with KRAB and SCAN domains 5 7.61 8.3 0.13 0.0 0.0 82.11 Detail
35 LIHC cuproptosis DBT dihydrolipoamide branched chain transacylase E2 10.84 9.66 -0.17 0.0 0.0 81.97 Detail
36 LIHC cuproptosis NDOR1 NADPH dependent diflavin oxidoreductase 1 8.07 9.19 0.19 0.0 0.0 80.74 Detail
37 LIHC cuproptosis POLD1 DNA polymerase delta 1, catalytic subunit 7.98 9.2 0.21 0.0 0.0 80.4 Detail
38 LIHC cuproptosis ATP6AP1 ATPase H+ transporting accessory protein 1 11.18 11.91 0.09 0.0 0.0 80.07 Detail
39 LIHC cuproptosis DAXX death domain associated protein 9.76 10.5 0.11 0.0 0.0 79.94 Detail
40 LIHC cuproptosis CCDC137 coiled-coil domain containing 137 8.18 9.18 0.17 0.0 0.0 79.77 Detail
41 LIHC cuproptosis DTYMK deoxythymidylate kinase 8.08 9.28 0.2 0.0 0.0 79.57 Detail
42 LIHC cuproptosis ACLY ATP citrate lyase 10.25 11.31 0.14 0.0 0.0 79.17 Detail
43 LIHC cuproptosis YEATS2 YEATS domain containing 2 7.67 8.79 0.2 0.0 0.0 78.66 Detail
44 LIHC cuproptosis SDHB succinate dehydrogenase complex iron sulfur subunit B 12.35 11.35 -0.12 0.0 0.0 78.63 Detail
45 LIHC cuproptosis UBE2D3 ubiquitin conjugating enzyme E2 D3 12.61 12.07 -0.06 0.0 0.0 78.09 Detail
46 LIHC cuproptosis SDHD succinate dehydrogenase complex subunit D 12.39 11.48 -0.11 0.0 0.0 77.89 Detail
47 LIHC cuproptosis RAD9A RAD9 checkpoint clamp component A 7.27 8.3 0.19 0.0 0.0 77.34 Detail
48 LIHC cuproptosis OGDHL oxoglutarate dehydrogenase L 12.63 10.15 -0.32 0.0 0.0 77.17 Detail
49 LIHC cuproptosis LOXL2 lysyl oxidase like 2 6.92 8.45 0.29 0.0 0.0 75.77 Detail
50 LIHC cuproptosis CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X 10.87 10.01 -0.12 0.0 0.0 74.95 Detail
51 LIHC cuproptosis CMPK1 cytidine/uridine monophosphate kinase 1 12.81 12.11 -0.08 0.0 0.0 74.49 Detail
52 LIHC cuproptosis SLC31A2 solute carrier family 31 member 2 9.21 8.02 -0.2 0.0 0.0 74.19 Detail
53 LIHC cuproptosis CENPJ centromere protein J 5.53 6.8 0.3 0.0 0.0 73.89 Detail
54 LIHC cuproptosis POLR2K RNA polymerase II, I and III subunit K 9.5 10.37 0.13 0.0 0.0 73.85 Detail
55 LIHC cuproptosis CCDC28B coiled-coil domain containing 28B 4.17 6.27 0.59 0.0 0.0 73.76 Detail
56 LIHC cuproptosis ZFAT zinc finger and AT-hook domain containing 6.92 7.71 0.15 0.0 0.0 73.06 Detail
57 LIHC cuproptosis SDHA succinate dehydrogenase complex flavoprotein subunit A 13.29 12.43 -0.1 0.0 0.0 72.32 Detail
58 LIHC cuproptosis MT1DP metallothionein 1D, pseudogene 5.73 2.77 -1.05 0.0 0.0 72.06 Detail
59 LIHC cuproptosis RTEL1 regulator of telomere elongation helicase 1 8.08 8.93 0.15 0.0 0.0 71.89 Detail
60 LIHC cuproptosis COX19 cytochrome c oxidase assembly factor COX19 7.31 8.28 0.18 0.0 0.0 71.84 Detail
61 LIHC cuproptosis MCM5 minichromosome maintenance complex component 5 9.14 10.45 0.19 0.0 0.0 71.72 Detail
62 LIHC cuproptosis HARS2 histidyl-tRNA synthetase 2, mitochondrial 8.97 9.55 0.09 0.0 0.0 71.64 Detail
63 LIHC cuproptosis CDK5RAP1 CDK5 regulatory subunit associated protein 1 8.78 9.26 0.08 0.0 0.0 71.28 Detail
64 LIHC cuproptosis NFE2L2 NFE2 like bZIP transcription factor 2 11.88 10.97 -0.11 0.0 0.0 69.94 Detail
65 LIHC cuproptosis SLC7A11 solute carrier family 7 member 11 2.51 5.87 1.23 0.0 0.0 69.75 Detail
66 LIHC cuproptosis NUP133 nucleoporin 133 9.24 9.82 0.09 0.0 0.0 69.1 Detail
67 LIHC cuproptosis DNA2 DNA replication helicase/nuclease 2 4.73 6.24 0.4 0.0 0.0 68.73 Detail
68 LIHC cuproptosis COX18 cytochrome c oxidase assembly factor COX18 9.37 8.64 -0.12 0.0 0.0 67.5 Detail
69 LIHC cuproptosis MRPL39 mitochondrial ribosomal protein L39 9.34 8.7 -0.1 0.0 0.0 67.47 Detail
70 LIHC cuproptosis PGP phosphoglycolate phosphatase 8.18 9.18 0.17 0.0 0.0 66.73 Detail
71 LIHC cuproptosis SERPINE1 serpin family E member 1 13.43 10.95 -0.29 0.0 0.0 66.47 Detail
72 LIHC cuproptosis MRPS21 mitochondrial ribosomal protein S21 10.0 10.9 0.12 0.0 0.0 66.3 Detail
73 LIHC cuproptosis SLC25A39 solute carrier family 25 member 39 11.45 12.18 0.09 0.0 0.0 66.24 Detail
74 LIHC cuproptosis ACO1 aconitase 1 12.7 11.79 -0.11 0.0 0.0 65.67 Detail
75 LIHC cuproptosis CS citrate synthase 10.6 11.28 0.09 0.0 0.0 65.52 Detail
76 LIHC cuproptosis DAPK2 death associated protein kinase 2 6.37 7.87 0.31 0.0 0.0 64.99 Detail
77 LIHC cuproptosis MT1A metallothionein 1A 9.36 6.29 -0.57 0.0 0.0 62.88 Detail
78 LIHC cuproptosis SLC25A19 solute carrier family 25 member 19 6.9 7.81 0.18 0.0 0.0 62.59 Detail
79 LIHC cuproptosis ALAS1 5'-aminolevulinate synthase 1 13.84 12.34 -0.17 0.0 0.0 61.73 Detail
80 LIHC cuproptosis TPK1 thiamin pyrophosphokinase 1 6.94 5.77 -0.27 0.0 0.0 61.65 Detail
81 LIHC cuproptosis GGPS1 geranylgeranyl diphosphate synthase 1 8.77 9.32 0.09 0.0 0.0 61.45 Detail
82 LIHC cuproptosis PRNP prion protein (Kanno blood group) 11.06 9.77 -0.18 0.0 0.0 61.44 Detail
83 LIHC cuproptosis NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase 9.42 9.97 0.08 0.0 0.0 61.39 Detail
84 LIHC cuproptosis WDR12 WD repeat domain 12 8.17 8.77 0.1 0.0 0.0 60.74 Detail
85 LIHC cuproptosis DPYD dihydropyrimidine dehydrogenase 11.0 9.77 -0.17 0.0 0.0 60.15 Detail
86 LIHC cuproptosis IFT81 intraflagellar transport 81 6.2 7.26 0.23 0.0 0.0 59.97 Detail
87 LIHC cuproptosis GTPBP4 GTP binding protein 4 9.22 9.82 0.09 0.0 0.0 58.62 Detail
88 LIHC cuproptosis PPP1R15A protein phosphatase 1 regulatory subunit 15A 10.82 9.78 -0.15 0.0 0.0 58.51 Detail
89 LIHC cuproptosis LDLR low density lipoprotein receptor 12.42 11.04 -0.17 0.0 0.0 58.35 Detail
90 LIHC cuproptosis UQCRC2 ubiquinol-cytochrome c reductase core protein 2 12.44 11.78 -0.08 0.0 0.0 58.25 Detail
91 LIHC cuproptosis GCSH glycine cleavage system protein H 7.12 5.8 -0.29 0.0 0.0 58.08 Detail
92 LIHC cuproptosis MT1B metallothionein 1B 2.34 0.52 -2.18 0.0 0.0 57.74 Detail
93 LIHC cuproptosis FDX1 ferredoxin 1 11.0 10.23 -0.1 0.0 0.0 57.06 Detail
94 LIHC cuproptosis AP1S1 adaptor related protein complex 1 subunit sigma 1 9.74 10.34 0.09 0.0 0.0 57.06 Detail
95 LIHC cuproptosis RPAP1 RNA polymerase II associated protein 1 8.93 9.45 0.08 0.0 0.0 56.86 Detail
96 LIHC cuproptosis HNRNPU heterogeneous nuclear ribonucleoprotein U 12.6 13.01 0.05 0.0 0.0 56.57 Detail
97 LIHC cuproptosis TLR3 toll like receptor 3 7.95 6.36 -0.32 0.0 0.0 56.48 Detail
98 LIHC cuproptosis AOC3 amine oxidase copper containing 3 9.82 8.95 -0.13 0.0 0.0 56.09 Detail
99 LIHC cuproptosis MAP2K2 mitogen-activated protein kinase kinase 2 10.96 11.57 0.08 0.0 0.0 55.91 Detail
100 LIHC cuproptosis DDX20 DEAD-box helicase 20 7.65 8.13 0.09 0.0 0.0 55.13 Detail
101 LIHC cuproptosis TANK TRAF family member associated NFKB activator 9.97 9.38 -0.09 0.0 0.0 55.03 Detail
102 LIHC cuproptosis NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 11.48 10.82 -0.09 0.0 0.0 54.74 Detail
103 LIHC cuproptosis HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 12.3 11.54 -0.09 0.0 0.0 54.49 Detail
104 LIHC cuproptosis PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.57 10.07 -0.07 0.0 0.0 54.32 Detail
105 LIHC cuproptosis CEPT1 choline/ethanolamine phosphotransferase 1 9.92 9.42 -0.08 0.0 0.0 54.0 Detail
106 LIHC cuproptosis DYNLRB1 dynein light chain roadblock-type 1 10.52 11.15 0.08 0.0 0.0 52.87 Detail
107 LIHC cuproptosis RRN3 RRN3 homolog, RNA polymerase I transcription factor 10.45 9.82 -0.09 0.0 0.0 52.8 Detail
108 LIHC cuproptosis TSC22D2 TSC22 domain family member 2 9.6 8.57 -0.16 0.0 0.0 52.46 Detail
109 LIHC cuproptosis HSF1 heat shock transcription factor 1 10.42 11.13 0.1 0.0 0.0 52.2 Detail
110 LIHC cuproptosis NOP2 NOP2 nucleolar protein 9.04 9.68 0.1 0.0 0.0 52.03 Detail
111 LIHC cuproptosis ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 10.31 10.87 0.08 0.0 0.0 51.51 Detail
112 LIHC cuproptosis MRPS14 mitochondrial ribosomal protein S14 8.74 9.19 0.07 0.0 0.0 50.61 Detail
113 LIHC cuproptosis NRF1 nuclear respiratory factor 1 7.69 8.12 0.08 0.0 0.0 50.52 Detail
114 LIHC cuproptosis MFN2 mitofusin 2 12.07 11.49 -0.07 0.0 0.0 49.98 Detail
115 LIHC cuproptosis UBE2I ubiquitin conjugating enzyme E2 I 9.87 10.37 0.07 0.0 0.0 49.86 Detail
116 LIHC cuproptosis AHR aryl hydrocarbon receptor 11.48 10.54 -0.12 0.0 0.0 49.58 Detail
117 LIHC cuproptosis SHMT2 serine hydroxymethyltransferase 2 12.85 12.26 -0.07 0.0 0.0 49.35 Detail
118 LIHC cuproptosis DOT1L DOT1 like histone lysine methyltransferase 8.91 9.65 0.11 0.0 0.0 49.01 Detail
119 LIHC cuproptosis ARF1 ADP ribosylation factor 1 13.26 13.67 0.04 0.0 0.0 48.89 Detail
120 LIHC cuproptosis PRND prion like protein doppel 1.02 3.18 1.64 0.0 0.0 48.61 Detail
121 LIHC cuproptosis SURF6 surfeit 6 9.2 9.64 0.07 0.0 0.0 48.01 Detail
122 LIHC cuproptosis COPS5 COP9 signalosome subunit 5 10.22 10.69 0.07 0.0 0.0 48.0 Detail
123 LIHC cuproptosis ABCB11 ATP binding cassette subfamily B member 11 10.44 7.73 -0.43 0.0 0.0 47.98 Detail
124 LIHC cuproptosis SOD1 superoxide dismutase 1 14.6 13.72 -0.09 0.0 0.0 47.85 Detail
125 LIHC cuproptosis PRKDC protein kinase, DNA-activated, catalytic subunit 10.54 11.29 0.1 0.0 0.0 47.71 Detail
126 LIHC cuproptosis TMEM199 transmembrane protein 199 8.76 9.15 0.06 0.0 0.0 47.64 Detail
127 LIHC cuproptosis ACD ACD shelterin complex subunit and telomerase recruitment factor 7.64 8.21 0.1 0.0 0.0 47.58 Detail
128 LIHC cuproptosis PSMB5 proteasome 20S subunit beta 5 11.12 11.52 0.05 0.0 0.0 47.35 Detail
129 LIHC cuproptosis NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 12.27 11.73 -0.07 0.0 0.0 46.61 Detail
130 LIHC cuproptosis MRPL34 mitochondrial ribosomal protein L34 11.14 10.56 -0.08 0.0 0.0 46.53 Detail
131 LIHC cuproptosis TKT transketolase 11.48 12.54 0.13 0.0 0.0 46.3 Detail
132 LIHC cuproptosis SNCA synuclein alpha 4.06 2.74 -0.57 0.0 0.0 45.61 Detail
133 LIHC cuproptosis DNM1L dynamin 1 like 9.32 9.82 0.08 0.0 0.0 45.13 Detail
134 LIHC cuproptosis PDE3B phosphodiesterase 3B 10.33 9.35 -0.14 0.0 0.0 45.1 Detail
135 LIHC cuproptosis IDH2 isocitrate dehydrogenase (NADP(+)) 2 13.22 12.39 -0.09 0.0 0.0 44.91 Detail
136 LIHC cuproptosis PHF5A PHD finger protein 5A 8.54 8.95 0.07 0.0 0.0 44.87 Detail
137 LIHC cuproptosis NLRP3 NLR family pyrin domain containing 3 5.75 4.46 -0.37 0.0 0.0 44.81 Detail
138 LIHC cuproptosis MFF mitochondrial fission factor 9.94 10.28 0.05 0.0 0.0 44.59 Detail
139 LIHC cuproptosis FAM111A FAM111 trypsin like peptidase A 8.54 9.15 0.1 0.0 0.0 44.47 Detail
140 LIHC cuproptosis PMVK phosphomevalonate kinase 10.71 11.3 0.08 0.0 0.0 44.24 Detail
141 LIHC cuproptosis SLC16A1 solute carrier family 16 member 1 11.77 10.79 -0.13 0.0 0.0 43.94 Detail
142 LIHC cuproptosis SEC14L2 SEC14 like lipid binding 2 12.89 11.23 -0.2 0.0 0.0 43.77 Detail
143 LIHC cuproptosis MRPS12 mitochondrial ribosomal protein S12 9.47 10.11 0.09 0.0 0.0 43.44 Detail
144 LIHC cuproptosis OXA1L OXA1L mitochondrial inner membrane protein 11.4 11.73 0.04 0.0 0.0 42.56 Detail
145 LIHC cuproptosis MRPL16 mitochondrial ribosomal protein L16 10.65 10.29 -0.05 0.0 0.0 42.43 Detail
146 LIHC cuproptosis COPZ1 COPI coat complex subunit zeta 1 11.52 11.87 0.04 0.0 0.0 42.39 Detail
147 LIHC cuproptosis NFKBIA NFKB inhibitor alpha 12.21 11.52 -0.08 0.0 0.0 42.19 Detail
148 LIHC cuproptosis GCLC glutamate-cysteine ligase catalytic subunit 11.88 11.13 -0.09 0.0 0.0 42.05 Detail
149 LIHC cuproptosis CCS copper chaperone for superoxide dismutase 10.96 10.35 -0.08 0.0 0.0 41.99 Detail
150 LIHC cuproptosis CAPRIN1 cell cycle associated protein 1 11.28 11.65 0.05 0.0 0.0 41.39 Detail
151 LIHC cuproptosis CCDC22 coiled-coil domain containing 22 8.86 9.23 0.06 0.0 0.0 41.33 Detail
152 LIHC cuproptosis API5 apoptosis inhibitor 5 11.05 10.76 -0.04 0.0 0.0 41.16 Detail
153 LIHC cuproptosis BRPF1 bromodomain and PHD finger containing 1 7.98 8.41 0.08 0.0 0.0 40.99 Detail
154 LIHC cuproptosis CYP1A1 cytochrome P450 family 1 subfamily A member 1 9.75 6.44 -0.6 0.0 0.0 40.9 Detail
155 LIHC cuproptosis RPL27 ribosomal protein L27 12.57 13.29 0.08 0.0 0.0 40.53 Detail
156 LIHC cuproptosis EXOC3 exocyst complex component 3 9.85 10.21 0.05 0.0 0.0 40.25 Detail
157 LIHC cuproptosis FZD8 frizzled class receptor 8 7.4 6.27 -0.24 0.0 0.0 39.65 Detail
158 LIHC cuproptosis TIMM9 translocase of inner mitochondrial membrane 9 8.61 9.08 0.08 0.0 0.0 39.16 Detail
159 LIHC cuproptosis SERPIND1 serpin family D member 1 15.17 14.11 -0.1 0.0 0.0 39.04 Detail
160 LIHC cuproptosis ELP3 elongator acetyltransferase complex subunit 3 9.82 9.39 -0.06 0.0 0.0 38.96 Detail
161 LIHC cuproptosis C6orf136 chromosome 6 open reading frame 136 8.68 9.17 0.08 0.0 0.0 38.65 Detail
162 LIHC cuproptosis COQ2 coenzyme Q2, polyprenyltransferase 8.29 7.73 -0.1 0.0 0.0 38.28 Detail
163 LIHC cuproptosis INTS6 integrator complex subunit 6 9.69 9.11 -0.09 0.0 0.0 38.22 Detail
164 LIHC cuproptosis MTO1 mitochondrial tRNA translation optimization 1 9.46 9.01 -0.07 0.0 0.0 37.95 Detail
165 LIHC cuproptosis MRPS2 mitochondrial ribosomal protein S2 10.81 10.38 -0.06 0.0 0.0 37.87 Detail
166 LIHC cuproptosis SPDYE1 speedy/RINGO cell cycle regulator family member E1 1.86 2.55 0.46 0.0 0.0 37.82 Detail
167 LIHC cuproptosis ANKRD49 ankyrin repeat domain 49 7.2 7.68 0.09 0.0 0.0 37.71 Detail
168 LIHC cuproptosis MRPL13 mitochondrial ribosomal protein L13 9.64 10.24 0.09 0.0 0.0 37.45 Detail
169 LIHC cuproptosis SAMM50 SAMM50 sorting and assembly machinery component 10.06 10.5 0.06 0.0 0.0 37.1 Detail
170 LIHC cuproptosis CD274 CD274 molecule 4.32 3.15 -0.45 0.0 0.0 36.85 Detail
171 LIHC cuproptosis SYMPK symplekin scaffold protein 10.89 11.28 0.05 0.0 0.0 36.42 Detail
172 LIHC cuproptosis FAS Fas cell surface death receptor 8.93 7.98 -0.16 0.0 0.0 36.4 Detail
173 LIHC cuproptosis SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit 10.39 10.74 0.05 0.0 0.0 36.25 Detail
174 LIHC cuproptosis RUVBL2 RuvB like AAA ATPase 2 10.52 10.97 0.06 0.0 0.0 36.11 Detail
175 LIHC cuproptosis ABCB4 ATP binding cassette subfamily B member 4 12.31 10.67 -0.21 0.0 0.0 35.64 Detail
176 LIHC cuproptosis BACE1 beta-secretase 1 10.8 10.36 -0.06 0.0 0.0 35.5 Detail
177 LIHC cuproptosis MRPL44 mitochondrial ribosomal protein L44 10.06 9.76 -0.04 0.0 0.0 34.98 Detail
178 LIHC cuproptosis XRN1 5'-3' exoribonuclease 1 9.99 9.47 -0.08 0.0 0.0 34.47 Detail
179 LIHC cuproptosis GFM1 G elongation factor mitochondrial 1 10.82 10.44 -0.05 0.0 0.0 34.4 Detail
180 LIHC cuproptosis MAP1LC3A microtubule associated protein 1 light chain 3 alpha 9.69 8.88 -0.13 0.0 0.0 34.13 Detail
181 LIHC cuproptosis IDH1 isocitrate dehydrogenase (NADP(+)) 1 13.53 13.0 -0.06 0.0 0.0 34.08 Detail
182 LIHC cuproptosis HSPH1 heat shock protein family H (Hsp110) member 1 9.88 10.45 0.08 0.0 0.0 33.77 Detail
183 LIHC cuproptosis EGFR epidermal growth factor receptor 10.53 9.6 -0.13 0.0 0.0 33.2 Detail
184 LIHC cuproptosis HMBS hydroxymethylbilane synthase 8.98 9.41 0.07 0.0 0.0 33.06 Detail
185 LIHC cuproptosis UBE2D2 ubiquitin conjugating enzyme E2 D2 10.32 10.61 0.04 0.0 0.0 32.4 Detail
186 LIHC cuproptosis SLC25A26 solute carrier family 25 member 26 9.28 8.9 -0.06 0.0 0.0 32.32 Detail
187 LIHC cuproptosis AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 9.86 9.49 -0.05 0.0 0.0 32.3 Detail
188 LIHC cuproptosis PDZD4 PDZ domain containing 4 6.16 5.03 -0.29 0.0 0.0 32.19 Detail
189 LIHC cuproptosis TAF4 TATA-box binding protein associated factor 4 8.34 8.77 0.07 0.0 0.0 32.16 Detail
190 LIHC cuproptosis DLST dihydrolipoamide S-succinyltransferase 11.73 11.33 -0.05 0.0 0.0 31.49 Detail
191 LIHC cuproptosis LARS2 leucyl-tRNA synthetase 2, mitochondrial 9.41 8.98 -0.07 0.0 0.0 31.49 Detail
192 LIHC cuproptosis DBR1 debranching RNA lariats 1 7.6 7.92 0.06 0.0 0.0 31.29 Detail
193 LIHC cuproptosis PDHX pyruvate dehydrogenase complex component X 9.84 9.52 -0.05 0.0 0.0 31.03 Detail
194 LIHC cuproptosis CCL20 C-C motif chemokine ligand 20 6.32 8.37 0.41 0.0 0.0 31.0 Detail
195 LIHC cuproptosis CYC1 cytochrome c1 11.79 12.32 0.06 0.0 0.0 30.67 Detail
196 LIHC cuproptosis BUD31 BUD31 homolog 9.95 10.41 0.07 0.0 0.0 30.38 Detail
197 LIHC cuproptosis MRPL55 mitochondrial ribosomal protein L55 10.01 10.57 0.08 0.0 0.0 30.1 Detail
198 LIHC cuproptosis SPARC secreted protein acidic and cysteine rich 12.56 13.23 0.07 0.0 0.0 29.75 Detail
199 LIHC cuproptosis RAD23B RAD23 homolog B, nucleotide excision repair protein 12.7 12.35 -0.04 0.0 0.0 29.73 Detail
200 LIHC cuproptosis PARS2 prolyl-tRNA synthetase 2, mitochondrial 6.91 7.32 0.08 0.0 0.0 29.69 Detail
201 LIHC cuproptosis PPA2 inorganic pyrophosphatase 2 10.41 9.98 -0.06 0.0 0.0 29.55 Detail
202 LIHC cuproptosis HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 13.42 13.66 0.03 0.0 0.0 29.35 Detail
203 LIHC cuproptosis SCO1 synthesis of cytochrome C oxidase 1 9.36 8.93 -0.07 0.0 0.0 29.23 Detail
204 LIHC cuproptosis ABCB7 ATP binding cassette subfamily B member 7 9.17 8.85 -0.05 0.0 0.0 29.22 Detail
205 LIHC cuproptosis NDUFS6 NADH:ubiquinone oxidoreductase subunit S6 10.63 11.14 0.07 0.0 0.0 28.89 Detail
206 LIHC cuproptosis SURF1 SURF1 cytochrome c oxidase assembly factor 10.99 10.53 -0.06 0.0 0.0 28.72 Detail
207 LIHC cuproptosis MRRF mitochondrial ribosome recycling factor 8.63 8.95 0.05 0.0 0.0 28.69 Detail
208 LIHC cuproptosis DLD dihydrolipoamide dehydrogenase 11.41 11.02 -0.05 0.0 0.0 28.62 Detail
209 LIHC cuproptosis PSMA6 proteasome 20S subunit alpha 6 11.13 11.45 0.04 0.0 0.0 28.33 Detail
210 LIHC cuproptosis NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 11.14 11.64 0.06 0.0 0.0 28.21 Detail
211 LIHC cuproptosis RPS19 ribosomal protein S19 13.37 14.01 0.07 0.0 0.0 27.72 Detail
212 LIHC cuproptosis GFRA3 GDNF family receptor alpha 3 1.94 1.39 -0.48 0.0 0.0 27.69 Detail
213 LIHC cuproptosis NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial 8.4 7.98 -0.07 0.0 0.0 27.49 Detail
214 LIHC cuproptosis CCL5 C-C motif chemokine ligand 5 9.35 8.33 -0.17 0.0 0.0 27.32 Detail
215 LIHC cuproptosis RPLP0 ribosomal protein lateral stalk subunit P0 14.14 14.68 0.05 0.0 0.0 27.26 Detail
216 LIHC cuproptosis LOX lysyl oxidase 5.6 6.68 0.26 0.0 0.0 27.21 Detail
217 LIHC cuproptosis CSTF3 cleavage stimulation factor subunit 3 9.0 9.29 0.05 0.0 0.0 27.11 Detail
218 LIHC cuproptosis FPGS folylpolyglutamate synthase 10.88 10.45 -0.06 0.0 0.0 26.98 Detail
219 LIHC cuproptosis ABCE1 ATP binding cassette subfamily E member 1 10.27 9.95 -0.05 0.0 0.0 25.58 Detail
220 LIHC cuproptosis CLEC11A C-type lectin domain containing 11A 7.52 6.56 -0.2 0.0 0.0 25.27 Detail
221 LIHC cuproptosis TRIM32 tripartite motif containing 32 7.35 7.76 0.08 0.0 0.0 25.22 Detail
222 LIHC cuproptosis UBA2 ubiquitin like modifier activating enzyme 2 10.23 10.58 0.05 0.0 0.0 24.45 Detail
223 LIHC cuproptosis RANGAP1 Ran GTPase activating protein 1 11.4 11.85 0.06 0.0 0.0 24.44 Detail
224 LIHC cuproptosis ANKRD9 ankyrin repeat domain 9 6.56 7.13 0.12 0.0 0.0 24.07 Detail
225 LIHC cuproptosis OSBPL9 oxysterol binding protein like 9 11.38 10.98 -0.05 0.0 0.0 23.84 Detail
226 LIHC cuproptosis DPH1 diphthamide biosynthesis 1 9.45 9.08 -0.06 0.0 0.0 23.64 Detail
227 LIHC cuproptosis FADD Fas associated via death domain 8.87 9.24 0.06 0.0 0.0 23.61 Detail
228 LIHC cuproptosis NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic 9.2 8.94 -0.04 0.0 0.0 23.61 Detail
229 LIHC cuproptosis N6AMT1 N-6 adenine-specific DNA methyltransferase 1 7.12 7.43 0.06 0.0 0.0 23.1 Detail
230 LIHC cuproptosis MRPL17 mitochondrial ribosomal protein L17 9.45 9.83 0.06 0.0 0.0 22.63 Detail
231 LIHC cuproptosis GNL3 G protein nucleolar 3 10.14 10.51 0.05 0.0 0.0 22.61 Detail
232 LIHC cuproptosis PPAT phosphoribosyl pyrophosphate amidotransferase 7.44 7.84 0.08 0.0 0.0 22.5 Detail
233 LIHC cuproptosis FAM96A cytosolic iron-sulfur assembly component 2A 11.42 11.03 -0.05 0.0 0.0 22.43 Detail
234 LIHC cuproptosis CIAPIN1 cytokine induced apoptosis inhibitor 1 9.38 9.7 0.05 0.0 0.0 22.01 Detail
235 LIHC cuproptosis MRPL52 mitochondrial ribosomal protein L52 9.44 9.91 0.07 0.0 0.0 21.63 Detail
236 LIHC cuproptosis GLS glutaminase 8.58 9.3 0.12 0.0 0.0 21.43 Detail
237 LIHC cuproptosis NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 12.03 12.57 0.06 0.0 0.0 21.17 Detail
238 LIHC cuproptosis NFS1 NFS1 cysteine desulfurase 10.25 9.98 -0.04 0.0 0.0 20.69 Detail
239 LIHC cuproptosis ATP7B ATPase copper transporting beta 9.73 9.05 -0.11 0.0 0.0 20.39 Detail
240 LIHC cuproptosis PRDM10 PR/SET domain 10 7.04 7.36 0.06 0.0 0.0 20.19 Detail
241 LIHC cuproptosis NNAT neuronatin 1.12 1.87 0.73 0.0 0.0 20.15 Detail
242 LIHC cuproptosis ISCA2 iron-sulfur cluster assembly 2 8.24 8.53 0.05 0.0 0.0 19.99 Detail
243 LIHC cuproptosis AFG3L2 AFG3 like matrix AAA peptidase subunit 2 10.92 10.66 -0.03 0.0 0.0 19.39 Detail
244 LIHC cuproptosis MRPS22 mitochondrial ribosomal protein S22 9.89 9.67 -0.03 0.0 0.0 19.32 Detail
245 LIHC cuproptosis SDSL serine dehydratase like 10.82 10.0 -0.11 0.0 0.0 19.25 Detail
246 LIHC cuproptosis FASLG Fas ligand 3.92 3.16 -0.31 0.0 0.0 19.1 Detail
247 LIHC cuproptosis BRCA1 BRCA1 DNA repair associated 6.62 7.42 0.17 0.0 0.0 18.79 Detail
248 LIHC cuproptosis MBTPS2 membrane bound transcription factor peptidase, site 2 9.72 9.39 -0.05 0.0 0.0 18.79 Detail
249 LIHC cuproptosis GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 10.55 10.76 0.03 0.0 0.0 18.6 Detail
250 LIHC cuproptosis ISCA1 iron-sulfur cluster assembly 1 9.93 9.66 -0.04 0.0 0.0 18.21 Detail
251 LIHC cuproptosis SSBP1 single stranded DNA binding protein 1 10.09 10.37 0.04 0.0 0.0 18.13 Detail
252 LIHC cuproptosis IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma 9.92 10.28 0.05 0.0 0.0 17.85 Detail
253 LIHC cuproptosis EIF4G1 eukaryotic translation initiation factor 4 gamma 1 13.59 13.34 -0.03 0.0 0.0 17.68 Detail
254 LIHC cuproptosis RMND1 required for meiotic nuclear division 1 homolog 9.44 9.09 -0.05 0.0 0.0 17.66 Detail
255 LIHC cuproptosis RPL28 ribosomal protein L28 13.28 13.81 0.06 0.0 0.0 17.38 Detail
256 LIHC cuproptosis SOD2 superoxide dismutase 2 14.26 13.57 -0.07 0.0 0.0 16.99 Detail
257 LIHC cuproptosis NDUFC1 NADH:ubiquinone oxidoreductase subunit C1 10.2 9.92 -0.04 0.0 0.0 16.89 Detail
258 LIHC cuproptosis TOP1MT DNA topoisomerase I mitochondrial 9.56 10.03 0.07 0.0 0.0 16.76 Detail
259 LIHC cuproptosis TADA2A transcriptional adaptor 2A 6.39 6.68 0.06 0.0 0.0 16.48 Detail
260 LIHC cuproptosis C7orf26 integrator complex subunit 15 8.83 9.09 0.04 0.0 0.0 16.45 Detail
261 LIHC cuproptosis COX15 cytochrome c oxidase assembly homolog COX15 10.38 10.17 -0.03 0.0 0.0 16.26 Detail
262 LIHC cuproptosis APP amyloid beta precursor protein 13.73 13.09 -0.07 0.0 0.0 15.85 Detail
263 LIHC cuproptosis ATOX1 antioxidant 1 copper chaperone 11.19 11.62 0.05 0.0 0.0 15.67 Detail
264 LIHC cuproptosis GLRX5 glutaredoxin 5 11.22 10.88 -0.04 0.0 0.0 15.44 Detail
265 LIHC cuproptosis AQP1 aquaporin 1 (Colton blood group) 11.06 10.4 -0.09 0.0 0.0 15.42 Detail
266 LIHC cuproptosis ATP8B1 ATPase phospholipid transporting 8B1 9.44 9.85 0.06 0.0 0.0 15.39 Detail
267 LIHC cuproptosis RPL19 ribosomal protein L19 14.09 14.47 0.04 0.0 0.0 15.17 Detail
268 LIHC cuproptosis TFAM transcription factor A, mitochondrial 8.98 8.72 -0.04 0.0 0.0 14.07 Detail
269 LIHC cuproptosis CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 9.52 9.8 0.04 0.0 0.0 13.91 Detail
270 LIHC cuproptosis UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 8.53 8.25 -0.05 0.0 0.0 13.88 Detail
271 LIHC cuproptosis HEPH hephaestin 6.94 6.24 -0.15 0.0 0.0 13.84 Detail
272 LIHC cuproptosis PDHB pyruvate dehydrogenase E1 subunit beta 11.07 10.82 -0.03 0.0 0.0 13.75 Detail
273 LIHC cuproptosis NDUFA8 NADH:ubiquinone oxidoreductase subunit A8 9.87 10.15 0.04 0.0 0.0 13.11 Detail
274 LIHC cuproptosis CMC1 C-X9-C motif containing 1 8.18 8.46 0.05 0.0 0.0 13.1 Detail
275 LIHC cuproptosis RPL10A ribosomal protein L10a 12.81 13.16 0.04 0.0 0.0 12.8 Detail
276 LIHC cuproptosis TRRAP transformation/transcription domain associated protein 9.84 10.08 0.04 0.0 0.0 12.78 Detail
277 LIHC cuproptosis PCBP2 poly(rC) binding protein 2 13.53 13.32 -0.02 0.0 0.0 12.43 Detail
278 LIHC cuproptosis PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 11.4 11.22 -0.02 0.0 0.0 12.0 Detail
279 LIHC cuproptosis MRPS16 mitochondrial ribosomal protein S16 11.05 11.24 0.02 0.0 0.01 11.66 Detail
280 LIHC cuproptosis ZNF365 zinc finger protein 365 0.79 1.43 0.86 0.0 0.01 11.47 Detail
281 LIHC cuproptosis SLC25A3 solute carrier family 25 member 3 13.04 13.26 0.02 0.0 0.01 11.4 Detail
282 LIHC cuproptosis PTPMT1 protein tyrosine phosphatase mitochondrial 1 9.42 9.62 0.03 0.0 0.01 11.11 Detail
283 LIHC cuproptosis RPS27A ribosomal protein S27a 12.64 13.0 0.04 0.0 0.01 11.0 Detail
284 LIHC cuproptosis STK11 serine/threonine kinase 11 10.19 10.37 0.03 0.0 0.01 10.67 Detail
285 LIHC cuproptosis ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 8.88 8.59 -0.05 0.0 0.01 10.54 Detail
286 LIHC cuproptosis NDUFA4 NDUFA4 mitochondrial complex associated 12.23 12.52 0.03 0.0 0.01 10.0 Detail
287 LIHC cuproptosis NFYC nuclear transcription factor Y subunit gamma 9.99 10.21 0.03 0.0 0.01 9.42 Detail
288 LIHC cuproptosis SLC25A32 solute carrier family 25 member 32 9.34 9.07 -0.04 0.01 0.01 9.23 Detail
289 LIHC cuproptosis COX7A1 cytochrome c oxidase subunit 7A1 6.22 5.74 -0.12 0.01 0.01 8.95 Detail
290 LIHC cuproptosis MRPS18A mitochondrial ribosomal protein S18A 10.04 10.29 0.04 0.01 0.01 8.66 Detail
291 LIHC cuproptosis EPC2 enhancer of polycomb homolog 2 8.39 8.13 -0.05 0.01 0.01 8.6 Detail
292 LIHC cuproptosis TNF tumor necrosis factor 3.35 2.67 -0.33 0.01 0.01 8.45 Detail
293 LIHC cuproptosis MRPS7 mitochondrial ribosomal protein S7 10.53 10.75 0.03 0.01 0.01 8.39 Detail
294 LIHC cuproptosis MRPL21 mitochondrial ribosomal protein L21 9.46 9.79 0.05 0.01 0.01 8.2 Detail
295 LIHC cuproptosis GCLM glutamate-cysteine ligase modifier subunit 10.0 9.54 -0.07 0.01 0.01 8.18 Detail
296 LIHC cuproptosis UQCRC1 ubiquinol-cytochrome c reductase core protein 1 13.07 12.81 -0.03 0.01 0.01 8.16 Detail
297 LIHC cuproptosis ABCB8 ATP binding cassette subfamily B member 8 9.96 10.21 0.04 0.01 0.01 8.06 Detail
298 LIHC cuproptosis DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 10.24 9.99 -0.04 0.01 0.01 8.06 Detail
299 LIHC cuproptosis NDUFA6 NADH:ubiquinone oxidoreductase subunit A6 10.79 11.05 0.04 0.01 0.01 8.06 Detail
300 LIHC cuproptosis COX6B1 cytochrome c oxidase subunit 6B1 12.13 12.51 0.04 0.01 0.01 8.0 Detail
301 LIHC cuproptosis CYP2D6 cytochrome P450 family 2 subfamily D member 6 13.26 12.21 -0.12 0.01 0.01 7.62 Detail
302 LIHC cuproptosis ABCB10 ATP binding cassette subfamily B member 10 9.31 9.54 0.04 0.01 0.01 7.55 Detail
303 LIHC cuproptosis CHMP4B charged multivesicular body protein 4B 11.09 11.35 0.03 0.01 0.01 7.33 Detail
304 LIHC cuproptosis SLFN11 schlafen family member 11 7.65 7.25 -0.08 0.01 0.01 7.32 Detail
305 LIHC cuproptosis GTF2B general transcription factor IIB 9.41 9.2 -0.03 0.01 0.01 7.29 Detail
306 LIHC cuproptosis FGD6 FYVE, RhoGEF and PH domain containing 6 7.64 8.07 0.08 0.01 0.01 7.19 Detail
307 LIHC cuproptosis CYCS cytochrome c, somatic 11.33 11.64 0.04 0.01 0.01 6.98 Detail
308 LIHC cuproptosis MRPS18C mitochondrial ribosomal protein S18C 8.73 8.51 -0.04 0.01 0.01 6.98 Detail
309 LIHC cuproptosis CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 10.49 10.28 -0.03 0.01 0.02 6.25 Detail
310 LIHC cuproptosis MRPL51 mitochondrial ribosomal protein L51 10.88 11.11 0.03 0.01 0.02 6.18 Detail
311 LIHC cuproptosis MRPL41 mitochondrial ribosomal protein L41 11.05 10.75 -0.04 0.01 0.02 6.06 Detail
312 LIHC cuproptosis RPAIN RPA interacting protein 9.09 8.87 -0.04 0.01 0.02 5.81 Detail
313 LIHC cuproptosis RPUSD3 RNA pseudouridine synthase D3 9.25 9.46 0.03 0.01 0.02 5.72 Detail
314 LIHC cuproptosis IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha 9.95 9.77 -0.03 0.01 0.02 5.51 Detail
315 LIHC cuproptosis NAPA NSF attachment protein alpha 12.4 12.18 -0.02 0.01 0.02 5.49 Detail
316 LIHC cuproptosis RPUSD4 RNA pseudouridine synthase D4 9.18 8.97 -0.03 0.01 0.02 4.99 Detail
317 LIHC cuproptosis IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta 10.68 10.86 0.02 0.01 0.02 4.75 Detail
318 LIHC cuproptosis NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 10.71 10.48 -0.03 0.01 0.02 4.24 Detail
319 LIHC cuproptosis CUTC cutC copper transporter 8.86 8.63 -0.04 0.02 0.03 3.72 Detail
320 LIHC cuproptosis PGK1 phosphoglycerate kinase 1 12.5 12.7 0.02 0.02 0.03 3.44 Detail
321 LIHC cuproptosis NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 12.46 12.25 -0.02 0.02 0.03 3.0 Detail
322 LIHC cuproptosis ULK2 unc-51 like autophagy activating kinase 2 7.54 6.85 -0.14 0.02 0.03 2.73 Detail
323 LIHC cuproptosis YARS2 tyrosyl-tRNA synthetase 2 8.08 8.25 0.03 0.02 0.03 2.61 Detail
324 LIHC cuproptosis SCAP SREBF chaperone 11.48 11.69 0.03 0.02 0.03 2.47 Detail
325 LIHC cuproptosis CIT citron rho-interacting serine/threonine kinase 6.6 7.19 0.12 0.02 0.04 1.93 Detail
326 LIHC cuproptosis RIPK3 receptor interacting serine/threonine kinase 3 5.26 4.82 -0.13 0.02 0.04 1.9 Detail
327 LIHC cuproptosis PCGF6 polycomb group ring finger 6 8.0 7.78 -0.04 0.03 0.04 1.53 Detail
328 LIHC cuproptosis ISCU iron-sulfur cluster assembly enzyme 10.86 10.71 -0.02 0.03 0.04 1.47 Detail
329 LIHC cuproptosis MRPL40 mitochondrial ribosomal protein L40 10.54 10.32 -0.03 0.03 0.04 1.47 Detail
330 LIHC cuproptosis EGLN1 egl-9 family hypoxia inducible factor 1 11.13 11.31 0.02 0.03 0.04 1.36 Detail
331 LIHC cuproptosis MRPL30 mitochondrial ribosomal protein L30 9.64 9.78 0.02 0.03 0.04 1.24 Detail
332 LIHC cuproptosis HSCB HscB mitochondrial iron-sulfur cluster cochaperone 8.85 8.63 -0.04 0.03 0.04 0.81 Detail
333 LIHC cuproptosis PDE12 phosphodiesterase 12 9.41 9.21 -0.03 0.03 0.05 0.46 Detail
334 LIHC cuproptosis DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 9.94 10.12 0.03 0.03 0.05 0.14 Detail
335 LIHC cuproptosis SOX2 SRY-box transcription factor 2 0.81 1.82 1.16 0.03 0.04 0.1 Detail
336 LIHC cuproptosis PARK7 Parkinsonism associated deglycase 12.42 12.17 -0.03 0.03 0.05 0.07 Detail
337 LIHC cuproptosis ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) 10.36 10.44 0.01 0.29 0.35 0.0 Detail
338 LIHC cuproptosis ATP7A ATPase copper transporting alpha 6.77 7.02 0.05 0.04 0.06 0.0 Detail
339 LIHC cuproptosis SCO2 synthesis of cytochrome C oxidase 2 9.73 9.65 -0.01 0.38 0.43 0.0 Detail
340 LIHC cuproptosis AOC1 amine oxidase copper containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
341 LIHC cuproptosis AQP2 aquaporin 2 0.09 0.16 0.9 0.48 0.54 0.0 Detail
342 LIHC cuproptosis BECN1 beclin 1 10.34 10.41 0.01 0.33 0.39 0.0 Detail
343 LIHC cuproptosis MT1HL1 metallothionein 1H like 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
344 LIHC cuproptosis MT3 metallothionein 3 0.6 1.65 1.47 0.05 0.08 0.0 Detail
345 LIHC cuproptosis MT4 metallothionein 4 0.0 0.03 inf 0.36 0.42 0.0 Detail
346 LIHC cuproptosis COMMD1 copper metabolism domain containing 1 8.54 8.47 -0.01 0.37 0.42 0.0 Detail
347 LIHC cuproptosis XIAP X-linked inhibitor of apoptosis 10.18 10.09 -0.01 0.17 0.21 0.0 Detail
348 LIHC cuproptosis STEAP2 STEAP2 metalloreductase 7.08 6.83 -0.05 0.7 0.73 0.0 Detail
349 LIHC cuproptosis SLC11A2 solute carrier family 11 member 2 10.12 10.08 -0.01 0.65 0.69 0.0 Detail
350 LIHC cuproptosis COX17 cytochrome c oxidase copper chaperone COX17 10.12 10.13 0.0 0.99 0.99 0.0 Detail
351 LIHC cuproptosis FKBP4 FKBP prolyl isomerase 4 11.6 11.73 0.02 0.25 0.3 0.0 Detail
352 LIHC cuproptosis HEPHL1 hephaestin like 1 0.78 0.9 0.2 0.7 0.73 0.0 Detail
353 LIHC cuproptosis MMGT1 membrane magnesium transporter 1 8.6 8.7 0.02 0.29 0.35 0.0 Detail
354 LIHC cuproptosis MLKL mixed lineage kinase domain like pseudokinase 7.1 7.2 0.02 0.35 0.41 0.0 Detail
355 LIHC cuproptosis RIPK1 receptor interacting serine/threonine kinase 1 10.21 10.09 -0.02 0.04 0.06 0.0 Detail
356 LIHC cuproptosis LIAS lipoic acid synthetase 8.1 8.11 0.0 0.88 0.9 0.0 Detail
357 LIHC cuproptosis LIPT1 lipoyltransferase 1 6.45 6.63 0.04 0.06 0.08 0.0 Detail
358 LIHC cuproptosis DLAT dihydrolipoamide S-acetyltransferase 9.46 9.67 0.03 0.08 0.11 0.0 Detail
359 LIHC cuproptosis MTF1 metal regulatory transcription factor 1 7.79 7.86 0.01 0.39 0.44 0.0 Detail
360 LIHC cuproptosis ACO2 aconitase 2 11.86 11.93 0.01 0.94 0.96 0.0 Detail
361 LIHC cuproptosis ACP1 acid phosphatase 1 10.98 11.09 0.01 0.11 0.14 0.0 Detail
362 LIHC cuproptosis ACTR10 actin related protein 10 9.55 9.62 0.01 0.25 0.31 0.0 Detail
363 LIHC cuproptosis ADGRE5 adhesion G protein-coupled receptor E5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
364 LIHC cuproptosis AOC2 amine oxidase copper containing 2 4.32 4.63 0.1 0.03 0.05 0.0 Detail
365 LIHC cuproptosis ARFGEF1-DT ARFGEF1 divergent transcript 0.0 0.0 0.0 0.0 0.0 0.0 Detail
366 LIHC cuproptosis ARHGEF39 Rho guanine nucleotide exchange factor 39 0.0 0.0 0.0 0.0 0.0 0.0 Detail
367 LIHC cuproptosis ARMH3 armadillo like helical domain containing 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
368 LIHC cuproptosis ATF4 activating transcription factor 4 12.71 12.76 0.01 0.7 0.73 0.0 Detail
369 LIHC cuproptosis ATL2 atlastin GTPase 2 10.28 10.23 -0.01 0.8 0.83 0.0 Detail
370 LIHC cuproptosis ATM ATM serine/threonine kinase 9.32 9.13 -0.03 0.17 0.22 0.0 Detail
371 LIHC cuproptosis ATP5PD ATP synthase peripheral stalk subunit d 0.0 0.0 0.0 0.0 0.0 0.0 Detail
372 LIHC cuproptosis ATP7BP1 ATPase copper transporting beta pseudogene 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
373 LIHC cuproptosis BARX1 BARX homeobox 1 2.03 1.95 -0.06 0.06 0.08 0.0 Detail
374 LIHC cuproptosis BCKDH protein phosphatase, Mg2+/Mn2+ dependent 1K 0.0 0.0 0.0 0.0 0.0 0.0 Detail
375 LIHC cuproptosis BCL2 BCL2 apoptosis regulator 7.09 6.8 -0.06 0.1 0.13 0.0 Detail
376 LIHC cuproptosis C1QBP complement C1q binding protein 10.83 10.62 -0.03 0.08 0.11 0.0 Detail
377 LIHC cuproptosis C6ORF136 chromosome 6 open reading frame 136 0.0 0.0 0.0 0.0 0.0 0.0 Detail
378 LIHC cuproptosis CCDC115 coiled-coil domain containing 115 9.15 9.01 -0.02 0.06 0.08 0.0 Detail
379 LIHC cuproptosis CCL8 C-C motif chemokine ligand 8 3.87 4.15 0.1 0.3 0.36 0.0 Detail
380 LIHC cuproptosis CDC16 cell division cycle 16 10.14 10.29 0.02 0.05 0.07 0.0 Detail
381 LIHC cuproptosis CDC27 cell division cycle 27 9.95 10.05 0.01 0.23 0.29 0.0 Detail
382 LIHC cuproptosis CERS2 ceramide synthase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
383 LIHC cuproptosis CERT1 ceramide transporter 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
384 LIHC cuproptosis CHTOP chromatin target of PRMT1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
385 LIHC cuproptosis CIAO1 cytosolic iron-sulfur assembly component 1 11.12 11.08 -0.01 0.13 0.17 0.0 Detail
386 LIHC cuproptosis CIAO2A cytosolic iron-sulfur assembly component 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
387 LIHC cuproptosis CIAO2B cytosolic iron-sulfur assembly component 2B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
388 LIHC cuproptosis CISD1 CDGSH iron sulfur domain 1 9.46 9.44 -0.0 0.91 0.93 0.0 Detail
389 LIHC cuproptosis CLUH clustered mitochondria homolog 0.0 0.0 0.0 0.0 0.0 0.0 Detail
390 LIHC cuproptosis CNN1 calponin 1 5.89 6.32 0.1 0.07 0.1 0.0 Detail
391 LIHC cuproptosis COA5 cytochrome c oxidase assembly factor 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
392 LIHC cuproptosis COA6 cytochrome c oxidase assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
393 LIHC cuproptosis COAS unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
394 LIHC cuproptosis COPB2 COPI coat complex subunit beta 2 11.39 11.45 0.01 0.22 0.27 0.0 Detail
395 LIHC cuproptosis copper鈥搝inc alloy (CZA) unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
396 LIHC cuproptosis COQ7 coenzyme Q7, hydroxylase 8.56 8.48 -0.01 0.26 0.32 0.0 Detail
397 LIHC cuproptosis COX11 cytochrome c oxidase copper chaperone COX11 10.24 10.31 0.01 0.44 0.5 0.0 Detail
398 LIHC cuproptosis COX14 cytochrome c oxidase assembly factor COX14 0.0 0.0 0.0 0.0 0.0 0.0 Detail
399 LIHC cuproptosis COX23 coiled-coil-helix-coiled-coil-helix domain containing 7 0.0 0.0 0.0 0.0 0.0 0.0 Detail
400 LIHC cuproptosis COX4I1 cytochrome c oxidase subunit 4I1 13.08 13.0 -0.01 0.26 0.32 0.0 Detail
401 LIHC cuproptosis COX7B cytochrome c oxidase subunit 7B 11.5 11.67 0.02 0.2 0.25 0.0 Detail
402 LIHC cuproptosis COX7C cytochrome c oxidase subunit 7C 12.41 12.47 0.01 0.71 0.74 0.0 Detail
403 LIHC cuproptosis CTR1 solute carrier family 31 member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
404 LIHC cuproptosis CTR2 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
405 LIHC cuproptosis DARS1 aspartyl-tRNA synthetase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
406 LIHC cuproptosis DCYTB cytochrome b reductase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
407 LIHC cuproptosis DHX15 DEAH-box helicase 15 10.4 10.54 0.02 0.05 0.07 0.0 Detail
408 LIHC cuproptosis DIP2B disco interacting protein 2 homolog B 9.84 9.89 0.01 0.33 0.39 0.0 Detail
409 LIHC cuproptosis DLG3 discs large MAGUK scaffold protein 3 6.91 6.65 -0.05 0.33 0.39 0.0 Detail
410 LIHC cuproptosis DMT1 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
411 LIHC cuproptosis DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 10.14 10.1 -0.01 0.6 0.65 0.0 Detail
412 LIHC cuproptosis EARS2 glutamyl-tRNA synthetase 2, mitochondrial 9.53 9.54 0.0 0.68 0.72 0.0 Detail
413 LIHC cuproptosis EFCC1 EF-hand and coiled-coil domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
414 LIHC cuproptosis EIF3I eukaryotic translation initiation factor 3 subunit I 11.83 11.92 0.01 0.27 0.33 0.0 Detail
415 LIHC cuproptosis ELF3 E74 like ETS transcription factor 3 11.12 11.19 0.01 0.49 0.55 0.0 Detail
416 LIHC cuproptosis ELOB elongin B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
417 LIHC cuproptosis EMC6 ER membrane protein complex subunit 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
418 LIHC cuproptosis ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.02 1.42 0.48 0.9 0.91 0.0 Detail
419 LIHC cuproptosis ERK1 mitogen-activated protein kinase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
420 LIHC cuproptosis FAK protein tyrosine kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
421 LIHC cuproptosis FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 8.24 8.4 0.03 0.17 0.22 0.0 Detail
422 LIHC cuproptosis FASTKD5 FAST kinase domains 5 8.92 8.78 -0.02 0.13 0.17 0.0 Detail
423 LIHC cuproptosis FAU FAU ubiquitin like and ribosomal protein S30 fusion 13.05 13.15 0.01 0.61 0.66 0.0 Detail
424 LIHC cuproptosis FDX2 ferredoxin 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
425 LIHC cuproptosis FDXR ferredoxin reductase 9.42 9.46 0.0 0.7 0.73 0.0 Detail
426 LIHC cuproptosis FOXD2-AS1 FOXD2 adjacent opposite strand RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
427 LIHC cuproptosis GADD45GIP1 GADD45G interacting protein 1 10.08 10.42 0.05 0.03 0.05 0.0 Detail
428 LIHC cuproptosis GATB glutamyl-tRNA amidotransferase subunit B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
429 LIHC cuproptosis GATC glutamyl-tRNA amidotransferase subunit C 5.04 5.16 0.03 0.36 0.42 0.0 Detail
430 LIHC cuproptosis GLS40 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
431 LIHC cuproptosis glycerophospholipid unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
432 LIHC cuproptosis GPX4 glutathione peroxidase 4 12.86 12.89 0.0 0.81 0.83 0.0 Detail
433 LIHC cuproptosis GRX1 glutaredoxin 0.0 0.0 0.0 0.0 0.0 0.0 Detail
434 LIHC cuproptosis GSH unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
435 LIHC cuproptosis GSS glutathione synthetase 10.45 10.59 0.02 0.09 0.12 0.0 Detail
436 LIHC cuproptosis GTPBP6 GTP binding protein 6 (putative) 0.0 0.0 0.0 0.0 0.0 0.0 Detail
437 LIHC cuproptosis H1-10-AS1 H1-10 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
438 LIHC cuproptosis H2AC6 H2A clustered histone 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
439 LIHC cuproptosis H2BC6-AS1 H2BC6 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
440 LIHC cuproptosis H3C1 H3 clustered histone 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
441 LIHC cuproptosis HCCS holocytochrome c synthase 9.11 9.02 -0.01 0.27 0.33 0.0 Detail
442 LIHC cuproptosis HIST1H3A H3 clustered histone 1 0.52 0.84 0.68 0.05 0.07 0.0 Detail
443 LIHC cuproptosis HSP70 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
444 LIHC cuproptosis HSPA8 heat shock protein family A (Hsp70) member 8 14.3 14.13 -0.02 0.37 0.43 0.0 Detail
445 LIHC cuproptosis HSPA9 heat shock protein family A (Hsp70) member 9 13.49 13.41 -0.01 0.37 0.42 0.0 Detail
446 LIHC cuproptosis HSPD1 heat shock protein family D (Hsp60) member 1 13.75 13.84 0.01 0.32 0.38 0.0 Detail
447 LIHC cuproptosis IBA57 iron-sulfur cluster assembly factor IBA57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
448 LIHC cuproptosis IL-8 C-X-C motif chemokine ligand 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
449 LIHC cuproptosis IMP4 IMP U3 small nucleolar ribonucleoprotein 4 10.0 10.06 0.01 0.51 0.57 0.0 Detail
450 LIHC cuproptosis INKA1 inka box actin regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
451 LIHC cuproptosis INSL4 insulin like 4 0.04 0.13 1.52 0.63 0.68 0.0 Detail
452 LIHC cuproptosis IOP1 cytosolic iron-sulfur assembly component 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
453 LIHC cuproptosis ISCU2 iron-sulfur cluster assembly enzyme 0.0 0.0 0.0 0.0 0.0 0.0 Detail
454 LIHC cuproptosis ISD11 LYR motif containing 4 0.0 0.0 0.0 0.0 0.0 0.0 Detail
455 LIHC cuproptosis ISG15 ISG15 ubiquitin like modifier 10.62 10.21 -0.06 0.25 0.3 0.0 Detail
456 LIHC cuproptosis KAT8 lysine acetyltransferase 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
457 LIHC cuproptosis KIDINS220 kinase D interacting substrate 220 10.01 9.87 -0.02 0.55 0.6 0.0 Detail
458 LIHC cuproptosis KLF5 KLF transcription factor 5 7.2 6.86 -0.07 0.57 0.62 0.0 Detail
459 LIHC cuproptosis KMT2A lysine methyltransferase 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
460 LIHC cuproptosis LACTB2 lactamase beta 2 9.89 9.73 -0.02 0.13 0.17 0.0 Detail
461 LIHC cuproptosis LASTR lncRNA associated with SART3 regulation of splicing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
462 LIHC cuproptosis LINC02038 long intergenic non-protein coding RNA 2038 0.0 0.0 0.0 0.0 0.0 0.0 Detail
463 LIHC cuproptosis LINC02154 long intergenic non-protein coding RNA 2154 0.0 0.0 0.0 0.0 0.0 0.0 Detail
464 LIHC cuproptosis LINC03085 long intergenic non-protein coding RNA 3085 0.0 0.0 0.0 0.0 0.0 0.0 Detail
465 LIHC cuproptosis LIPT2 lipoyl(octanoyl) transferase 2 4.74 4.76 0.0 0.77 0.8 0.0 Detail
466 LIHC cuproptosis LONP1 lon peptidase 1, mitochondrial 11.82 11.77 -0.01 0.45 0.51 0.0 Detail
467 LIHC cuproptosis MAD2L2 mitotic arrest deficient 2 like 2 9.35 9.57 0.03 0.08 0.11 0.0 Detail
468 LIHC cuproptosis MADD MAP kinase activating death domain 9.71 9.77 0.01 0.54 0.6 0.0 Detail
469 LIHC cuproptosis MAL2 mal, T cell differentiation protein 2 10.47 10.51 0.01 0.09 0.12 0.0 Detail
470 LIHC cuproptosis MAN2C1 mannosidase alpha class 2C member 1 10.57 10.61 0.01 0.27 0.33 0.0 Detail
471 LIHC cuproptosis MARCHF5 membrane associated ring-CH-type finger 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
472 LIHC cuproptosis MARS2 methionyl-tRNA synthetase 2, mitochondrial 7.89 7.73 -0.03 0.23 0.29 0.0 Detail
473 LIHC cuproptosis MAU2 MAU2 sister chromatid cohesion factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
474 LIHC cuproptosis MBTPS1 membrane bound transcription factor peptidase, site 1 10.97 10.79 -0.02 0.03 0.05 0.0 Detail
475 LIHC cuproptosis MCAT malonyl-CoA-acyl carrier protein transacylase 8.99 8.8 -0.03 0.04 0.06 0.0 Detail
476 LIHC cuproptosis MCMBP minichromosome maintenance complex binding protein 0.0 0.0 0.0 0.0 0.0 0.0 Detail
477 LIHC cuproptosis MCUR1 mitochondrial calcium uniporter regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
478 LIHC cuproptosis MDH2 malate dehydrogenase 2 12.64 12.7 0.01 0.5 0.56 0.0 Detail
479 LIHC cuproptosis MECR mitochondrial trans-2-enoyl-CoA reductase 8.86 8.9 0.01 0.53 0.59 0.0 Detail
480 LIHC cuproptosis MEK1 mitogen-activated protein kinase kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
481 LIHC cuproptosis MEK2 mitogen-activated protein kinase kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
482 LIHC cuproptosis METTL17 methyltransferase like 17 0.0 0.0 0.0 0.0 0.0 0.0 Detail
483 LIHC cuproptosis MOXD1 monooxygenase DBH like 1 5.62 5.24 -0.1 0.33 0.39 0.0 Detail
484 LIHC cuproptosis MPC1 mitochondrial pyruvate carrier 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
485 LIHC cuproptosis MPI mannose phosphate isomerase 9.91 9.84 -0.01 0.27 0.32 0.0 Detail
486 LIHC cuproptosis MPZL3 myelin protein zero like 3 4.67 4.16 -0.17 0.07 0.1 0.0 Detail
487 LIHC cuproptosis MRM2 mitochondrial rRNA methyltransferase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
488 LIHC cuproptosis MRPL12 mitochondrial ribosomal protein L12 11.36 11.4 0.01 0.82 0.85 0.0 Detail
489 LIHC cuproptosis MRPL14 mitochondrial ribosomal protein L14 10.6 10.87 0.04 0.08 0.11 0.0 Detail
490 LIHC cuproptosis MRPL15 mitochondrial ribosomal protein L15 10.37 10.57 0.03 0.1 0.13 0.0 Detail
491 LIHC cuproptosis MRPL2 mitochondrial ribosomal protein L2 10.4 10.47 0.01 0.69 0.73 0.0 Detail
492 LIHC cuproptosis MRPL36 mitochondrial ribosomal protein L36 9.11 9.22 0.02 0.37 0.42 0.0 Detail
493 LIHC cuproptosis MRPL53 mitochondrial ribosomal protein L53 9.73 9.96 0.03 0.04 0.06 0.0 Detail
494 LIHC cuproptosis MRPL57 mitochondrial ribosomal protein L57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
495 LIHC cuproptosis MRPS11 mitochondrial ribosomal protein S11 9.62 9.77 0.02 0.07 0.09 0.0 Detail
496 LIHC cuproptosis MRPS18B mitochondrial ribosomal protein S18B 11.23 11.28 0.01 0.61 0.66 0.0 Detail
497 LIHC cuproptosis MRPS25 mitochondrial ribosomal protein S25 10.44 10.47 0.0 0.9 0.91 0.0 Detail
498 LIHC cuproptosis MRPS30 mitochondrial ribosomal protein S30 9.23 9.11 -0.02 0.04 0.06 0.0 Detail
499 LIHC cuproptosis MRPS33 mitochondrial ribosomal protein S33 9.81 9.86 0.01 0.55 0.6 0.0 Detail
500 LIHC cuproptosis MRPS5 mitochondrial ribosomal protein S5 10.64 10.63 -0.0 0.64 0.68 0.0 Detail
501 LIHC cuproptosis MRPS9 mitochondrial ribosomal protein S9 9.36 9.36 -0.0 0.99 0.99 0.0 Detail
502 LIHC cuproptosis MT1 metallothionein 1A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
503 LIHC cuproptosis MT2 metallothionein 1B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
504 LIHC cuproptosis MT3A unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
505 LIHC cuproptosis MT-CO1 mitochondrially encoded cytochrome c oxidase I 0.0 0.0 0.0 0.0 0.0 0.0 Detail
506 LIHC cuproptosis MT-CO2 mitochondrially encoded cytochrome c oxidase II 0.0 0.0 0.0 0.0 0.0 0.0 Detail
507 LIHC cuproptosis MTCO2P12 MT-CO2 pseudogene 12 0.0 0.0 0.0 0.0 0.0 0.0 Detail
508 LIHC cuproptosis MT-CO3 mitochondrially encoded cytochrome c oxidase III 0.0 0.0 0.0 0.0 0.0 0.0 Detail
509 LIHC cuproptosis MT unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
510 LIHC cuproptosis MTERF1 mitochondrial transcription termination factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
511 LIHC cuproptosis MTFR1 mitochondrial fission regulator 1 9.93 10.01 0.01 0.54 0.59 0.0 Detail
512 LIHC cuproptosis MTFR1L mitochondrial fission regulator 1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
513 LIHC cuproptosis MTG1 mitochondrial ribosome associated GTPase 1 9.77 9.92 0.02 0.12 0.15 0.0 Detail
514 LIHC cuproptosis MTIF3 mitochondrial translational initiation factor 3 9.76 9.82 0.01 0.58 0.64 0.0 Detail
515 LIHC cuproptosis mTOR mechanistic target of rapamycin kinase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
516 LIHC cuproptosis MUC20 mucin 20, cell surface associated 7.55 7.62 0.01 0.97 0.98 0.0 Detail
517 LIHC cuproptosis NARS2 asparaginyl-tRNA synthetase 2, mitochondrial 9.17 8.99 -0.03 0.09 0.12 0.0 Detail
518 LIHC cuproptosis NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 11.68 11.67 -0.0 0.72 0.75 0.0 Detail
519 LIHC cuproptosis NDUFA9 NADH:ubiquinone oxidoreductase subunit A9 10.85 10.75 -0.01 0.34 0.39 0.0 Detail
520 LIHC cuproptosis NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
521 LIHC cuproptosis NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 11.21 11.15 -0.01 0.31 0.37 0.0 Detail
522 LIHC cuproptosis NDUFB11 NADH:ubiquinone oxidoreductase subunit B11 11.48 11.48 0.0 0.54 0.6 0.0 Detail
523 LIHC cuproptosis NDUFB2 NADH:ubiquinone oxidoreductase subunit B2 11.14 11.1 -0.01 0.49 0.55 0.0 Detail
524 LIHC cuproptosis NDUFB4 NADH:ubiquinone oxidoreductase subunit B4 11.13 11.21 0.01 0.62 0.66 0.0 Detail
525 LIHC cuproptosis NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 10.84 10.74 -0.01 0.07 0.1 0.0 Detail
526 LIHC cuproptosis NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 10.29 10.29 0.0 0.63 0.67 0.0 Detail
527 LIHC cuproptosis NDUFB7 NADH:ubiquinone oxidoreductase subunit B7 11.23 11.39 0.02 0.28 0.34 0.0 Detail
528 LIHC cuproptosis NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 12.14 12.07 -0.01 0.53 0.59 0.0 Detail
529 LIHC cuproptosis NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 12.29 12.33 0.01 0.64 0.68 0.0 Detail
530 LIHC cuproptosis NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 11.15 11.05 -0.01 0.06 0.09 0.0 Detail
531 LIHC cuproptosis NFU1 NFU1 iron-sulfur cluster scaffold 8.98 9.08 0.02 0.22 0.28 0.0 Detail
532 LIHC cuproptosis NPL4 NPL4 homolog, ubiquitin recognition factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
533 LIHC cuproptosis NTHL1 nth like DNA glycosylase 1 9.8 9.46 -0.05 0.04 0.06 0.0 Detail
534 LIHC cuproptosis NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic 10.47 10.51 0.0 0.69 0.72 0.0 Detail
535 LIHC cuproptosis P3H3 prolyl 3-hydroxylase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
536 LIHC cuproptosis p53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
537 LIHC cuproptosis P53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
538 LIHC cuproptosis p97 eukaryotic translation initiation factor 4 gamma 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
539 LIHC cuproptosis PDHA pyruvate dehydrogenase E1 subunit alpha 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
540 LIHC cuproptosis PDH pyruvate dehydrogenase phosphatase catalytic subunit 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
541 LIHC cuproptosis PDK1 pyruvate dehydrogenase kinase 1 8.23 8.39 0.03 0.24 0.3 0.0 Detail
542 LIHC cuproptosis PET100 PET100 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
543 LIHC cuproptosis PET117 PET117 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
544 LIHC cuproptosis PFKP phosphofructokinase, platelet 6.85 7.54 0.14 0.05 0.07 0.0 Detail
545 LIHC cuproptosis PHOB unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
546 LIHC cuproptosis PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.0 0.0 0.0 0.0 0.0 0.0 Detail
547 LIHC cuproptosis PITRM1 pitrilysin metallopeptidase 1 10.83 10.67 -0.02 0.03 0.05 0.0 Detail
548 LIHC cuproptosis PLOD1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 12.38 12.52 0.02 0.17 0.22 0.0 Detail
549 LIHC cuproptosis POLE DNA polymerase epsilon, catalytic subunit 9.77 9.84 0.01 0.62 0.66 0.0 Detail
550 LIHC cuproptosis POLG DNA polymerase gamma, catalytic subunit 9.82 9.85 0.0 0.47 0.53 0.0 Detail
551 LIHC cuproptosis POLR2B RNA polymerase II subunit B 10.13 10.23 0.01 0.06 0.08 0.0 Detail
552 LIHC cuproptosis POT1 protection of telomeres 1 8.52 8.48 -0.01 0.67 0.71 0.0 Detail
553 LIHC cuproptosis PPIE peptidylprolyl isomerase E 9.5 9.49 -0.0 0.98 0.99 0.0 Detail
554 LIHC cuproptosis PRDX1 peroxiredoxin 1 13.28 13.41 0.01 0.14 0.17 0.0 Detail
555 LIHC cuproptosis PSMD6 proteasome 26S subunit, non-ATPase 6 10.32 10.2 -0.02 0.04 0.06 0.0 Detail
556 LIHC cuproptosis PTCD3 pentatricopeptide repeat domain 3 10.29 10.18 -0.02 0.1 0.13 0.0 Detail
557 LIHC cuproptosis PURG purine rich element binding protein G 0.39 0.71 0.87 0.06 0.09 0.0 Detail
558 LIHC cuproptosis QRSL1 glutaminyl-tRNA amidotransferase subunit QRSL1 8.63 8.73 0.02 0.1 0.14 0.0 Detail
559 LIHC cuproptosis RANTES C-C motif chemokine ligand 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
560 LIHC cuproptosis RB1 RB transcriptional corepressor 1 9.17 8.81 -0.06 0.09 0.12 0.0 Detail
561 LIHC cuproptosis RCC1L RCC1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
562 LIHC cuproptosis REXO2 RNA exonuclease 2 9.42 9.42 -0.0 0.96 0.97 0.0 Detail
563 LIHC cuproptosis RHOV ras homolog family member V 2.73 2.74 0.01 0.18 0.22 0.0 Detail
564 LIHC cuproptosis RPL3 ribosomal protein L3 15.13 15.06 -0.01 0.33 0.39 0.0 Detail
565 LIHC cuproptosis RPL7A ribosomal protein L7a 13.37 13.62 0.03 0.05 0.07 0.0 Detail
566 LIHC cuproptosis RPS25 ribosomal protein S25 12.71 12.9 0.02 0.09 0.12 0.0 Detail
567 LIHC cuproptosis RSL1D1 ribosomal L1 domain containing 1 11.36 11.42 0.01 0.64 0.68 0.0 Detail
568 LIHC cuproptosis S6K1 ribosomal protein S6 kinase B1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
569 LIHC cuproptosis SARS2 seryl-tRNA synthetase 2, mitochondrial 8.97 8.98 0.0 0.97 0.98 0.0 Detail
570 LIHC cuproptosis SDHAF2 succinate dehydrogenase complex assembly factor 2 9.63 9.66 0.0 0.87 0.89 0.0 Detail
571 LIHC cuproptosis SDHC succinate dehydrogenase complex subunit C 12.0 12.13 0.02 0.09 0.12 0.0 Detail
572 LIHC cuproptosis SEPTIN1 septin 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
573 LIHC cuproptosis SGF29 SAGA complex associated factor 29 0.0 0.0 0.0 0.0 0.0 0.0 Detail
574 LIHC cuproptosis SLC16A6 solute carrier family 16 member 6 3.31 3.15 -0.07 0.34 0.4 0.0 Detail
575 LIHC cuproptosis SLC25A51 solute carrier family 25 member 51 0.0 0.0 0.0 0.0 0.0 0.0 Detail
576 LIHC cuproptosis SLC30A10 solute carrier family 30 member 10 9.57 9.54 -0.01 0.23 0.28 0.0 Detail
577 LIHC cuproptosis SLC30A7 solute carrier family 30 member 7 9.79 9.65 -0.02 0.06 0.08 0.0 Detail
578 LIHC cuproptosis SLC33A1 solute carrier family 33 member 1 9.41 9.56 0.02 0.07 0.09 0.0 Detail
579 LIHC cuproptosis SLC52A2 solute carrier family 52 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
580 LIHC cuproptosis SLC7A5 solute carrier family 7 member 5 8.7 8.5 -0.03 0.66 0.7 0.0 Detail
581 LIHC cuproptosis SMAD3-AS1 SMAD3 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
582 LIHC cuproptosis SOD3 superoxide dismutase 3 7.85 7.39 -0.09 0.27 0.33 0.0 Detail
583 LIHC cuproptosis sp1 Sp1 transcription factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
584 LIHC cuproptosis SP1 Sp1 transcription factor 10.55 10.67 0.02 0.07 0.1 0.0 Detail
585 LIHC cuproptosis SPATA13 spermatogenesis associated 13 8.25 7.49 -0.14 0.03 0.05 0.0 Detail
586 LIHC cuproptosis SPATA5 AFG2 AAA ATPase homolog A 6.65 6.78 0.03 0.32 0.38 0.0 Detail
587 LIHC cuproptosis SRP54 signal recognition particle 54 10.49 10.32 -0.02 0.06 0.09 0.0 Detail
588 LIHC cuproptosis STARD7 StAR related lipid transfer domain containing 7 11.66 11.74 0.01 0.38 0.43 0.0 Detail
589 LIHC cuproptosis STEAP4 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
590 LIHC cuproptosis STEAP STEAP family member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
591 LIHC cuproptosis TAF6L TATA-box binding protein associated factor 6 like 8.92 8.89 -0.0 1.0 1.0 0.0 Detail
592 LIHC cuproptosis TARS2 threonyl-tRNA synthetase 2, mitochondrial 9.88 10.03 0.02 0.08 0.11 0.0 Detail
593 LIHC cuproptosis TEDC1 tubulin epsilon and delta complex 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
594 LIHC cuproptosis TEFM transcription elongation factor, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 Detail
595 LIHC cuproptosis TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
596 LIHC cuproptosis TMEM191B transmembrane protein 191B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
597 LIHC cuproptosis TP53 tumor protein p53 9.63 9.5 -0.02 0.59 0.64 0.0 Detail
598 LIHC cuproptosis TPI1 triosephosphate isomerase 1 13.11 13.15 0.0 0.81 0.84 0.0 Detail
599 LIHC cuproptosis TRAPPC11 trafficking protein particle complex subunit 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
600 LIHC cuproptosis TUBGCP4 tubulin gamma complex component 4 7.21 7.13 -0.02 0.5 0.56 0.0 Detail
601 LIHC cuproptosis TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 10.07 10.0 -0.01 0.43 0.49 0.0 Detail
602 LIHC cuproptosis TWNK twinkle mtDNA helicase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
603 LIHC cuproptosis TYR tyrosinase 0.03 0.25 3.16 0.08 0.11 0.0 Detail
604 LIHC cuproptosis U2SURP U2 snRNP associated SURP domain containing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
605 LIHC cuproptosis UBE2D1 ubiquitin conjugating enzyme E2 D1 8.06 8.2 0.03 0.12 0.15 0.0 Detail
606 LIHC cuproptosis UlK1 unc-51 like autophagy activating kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
607 LIHC cuproptosis ULK1 unc-51 like autophagy activating kinase 1 10.45 10.66 0.03 0.06 0.09 0.0 Detail
608 LIHC cuproptosis UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
609 LIHC cuproptosis UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
610 LIHC cuproptosis UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 11.17 11.29 0.01 0.36 0.42 0.0 Detail
611 LIHC cuproptosis USE1 unconventional SNARE in the ER 1 8.97 9.17 0.03 0.08 0.11 0.0 Detail
612 LIHC cuproptosis UTP25 UTP25 small subunit processome component 0.0 0.0 0.0 0.0 0.0 0.0 Detail
613 LIHC cuproptosis VARS2 valyl-tRNA synthetase 2, mitochondrial 10.15 10.26 0.02 0.24 0.3 0.0 Detail
614 LIHC cuproptosis VEGFA vascular endothelial growth factor A 11.64 11.75 0.01 0.46 0.52 0.0 Detail
615 LIHC cuproptosis WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 8.07 8.22 0.03 0.09 0.12 0.0 Detail
616 LIHC cuproptosis xCT solute carrier family 7 member 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
617 LIHC cuproptosis YAE1 YAE1 maturation factor of ABCE1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
618 LIHC cuproptosis YAP1 Yes1 associated transcriptional regulator 10.62 10.57 -0.01 0.77 0.8 0.0 Detail
619 LIHC cuproptosis ZBP1 Z-DNA binding protein 1 3.85 3.38 -0.19 0.09 0.12 0.0 Detail
620 LIHC cuproptosis ZBTB11 zinc finger and BTB domain containing 11 8.56 8.68 0.02 0.15 0.19 0.0 Detail

Ensemble learning for LIHC based on specific cuproptosis gene regulaors.