Disease associated with RCD disease & gene list




LUAD specific cuproptosis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 LUAD cuproptosis CAT catalase 12.82 10.79 -0.25 0.0 0.0 100.0 Detail
2 LUAD cuproptosis PPAT phosphoribosyl pyrophosphate amidotransferase 6.69 8.55 0.35 0.0 0.0 99.26 Detail
3 LUAD cuproptosis ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 9.71 10.98 0.18 0.0 0.0 98.83 Detail
4 LUAD cuproptosis AOC3 amine oxidase copper containing 3 12.87 9.93 -0.37 0.0 0.0 98.8 Detail
5 LUAD cuproptosis ANLN anillin, actin binding protein 5.67 9.31 0.71 0.0 0.0 96.86 Detail
6 LUAD cuproptosis HSPD1 heat shock protein family D (Hsp60) member 1 11.53 12.77 0.15 0.0 0.0 96.58 Detail
7 LUAD cuproptosis PRC1 protein regulator of cytokinesis 1 6.74 9.18 0.45 0.0 0.0 96.49 Detail
8 LUAD cuproptosis TARS2 threonyl-tRNA synthetase 2, mitochondrial 8.44 9.38 0.15 0.0 0.0 96.08 Detail
9 LUAD cuproptosis FOXM1 forkhead box M1 5.93 9.27 0.64 0.0 0.0 95.79 Detail
10 LUAD cuproptosis WDR12 WD repeat domain 12 7.55 8.8 0.22 0.0 0.0 94.8 Detail
11 LUAD cuproptosis SHMT2 serine hydroxymethyltransferase 2 9.56 10.97 0.2 0.0 0.0 94.19 Detail
12 LUAD cuproptosis DAPK2 death associated protein kinase 2 10.44 8.11 -0.36 0.0 0.0 94.17 Detail
13 LUAD cuproptosis TRAIP TRAF interacting protein 4.43 6.37 0.52 0.0 0.0 93.73 Detail
14 LUAD cuproptosis GNL3 G protein nucleolar 3 9.49 10.64 0.16 0.0 0.0 93.2 Detail
15 LUAD cuproptosis LDLR low density lipoprotein receptor 12.82 10.72 -0.26 0.0 0.0 93.05 Detail
16 LUAD cuproptosis PPP1R15A protein phosphatase 1 regulatory subunit 15A 12.48 10.61 -0.23 0.0 0.0 93.05 Detail
17 LUAD cuproptosis SLC25A39 solute carrier family 25 member 39 10.53 11.76 0.16 0.0 0.0 92.68 Detail
18 LUAD cuproptosis DNA2 DNA replication helicase/nuclease 2 4.75 6.99 0.56 0.0 0.0 92.28 Detail
19 LUAD cuproptosis ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) 7.68 9.4 0.29 0.0 0.0 90.21 Detail
20 LUAD cuproptosis PDK1 pyruvate dehydrogenase kinase 1 7.54 9.1 0.27 0.0 0.0 89.6 Detail
21 LUAD cuproptosis COX7A1 cytochrome c oxidase subunit 7A1 8.17 6.21 -0.4 0.0 0.0 89.53 Detail
22 LUAD cuproptosis NSF N-ethylmaleimide sensitive factor, vesicle fusing ATPase 9.83 10.63 0.11 0.0 0.0 88.91 Detail
23 LUAD cuproptosis ZNF365 zinc finger protein 365 7.11 4.82 -0.56 0.0 0.0 88.86 Detail
24 LUAD cuproptosis SLC7A5 solute carrier family 7 member 5 8.52 10.94 0.36 0.0 0.0 88.59 Detail
25 LUAD cuproptosis CDKN3 cyclin dependent kinase inhibitor 3 3.74 6.89 0.88 0.0 0.0 88.56 Detail
26 LUAD cuproptosis IDH2 isocitrate dehydrogenase (NADP(+)) 2 10.17 11.35 0.16 0.0 0.0 88.44 Detail
27 LUAD cuproptosis MYO1B myosin IB 12.61 11.57 -0.12 0.0 0.0 88.44 Detail
28 LUAD cuproptosis UBE2I ubiquitin conjugating enzyme E2 I 10.37 10.97 0.08 0.0 0.0 88.38 Detail
29 LUAD cuproptosis CDK1 cyclin dependent kinase 1 6.84 9.1 0.41 0.0 0.0 87.97 Detail
30 LUAD cuproptosis CSTF3 cleavage stimulation factor subunit 3 8.62 9.25 0.1 0.0 0.0 86.33 Detail
31 LUAD cuproptosis HMBS hydroxymethylbilane synthase 7.92 9.15 0.21 0.0 0.0 85.56 Detail
32 LUAD cuproptosis NFS1 NFS1 cysteine desulfurase 8.32 9.0 0.11 0.0 0.0 85.35 Detail
33 LUAD cuproptosis NOP2 NOP2 nucleolar protein 8.61 9.73 0.18 0.0 0.0 85.21 Detail
34 LUAD cuproptosis TPI1 triosephosphate isomerase 1 12.19 13.28 0.12 0.0 0.0 84.82 Detail
35 LUAD cuproptosis ULK2 unc-51 like autophagy activating kinase 2 9.75 8.68 -0.17 0.0 0.0 84.44 Detail
36 LUAD cuproptosis AP1S1 adaptor related protein complex 1 subunit sigma 1 9.04 10.11 0.16 0.0 0.0 84.12 Detail
37 LUAD cuproptosis EARS2 glutamyl-tRNA synthetase 2, mitochondrial 8.55 9.3 0.12 0.0 0.0 84.04 Detail
38 LUAD cuproptosis COPB2 COPI coat complex subunit beta 2 11.28 11.92 0.08 0.0 0.0 83.93 Detail
39 LUAD cuproptosis GSS glutathione synthetase 9.41 10.19 0.11 0.0 0.0 82.96 Detail
40 LUAD cuproptosis PARS2 prolyl-tRNA synthetase 2, mitochondrial 6.19 7.14 0.21 0.0 0.0 82.67 Detail
41 LUAD cuproptosis MRPL12 mitochondrial ribosomal protein L12 9.01 10.25 0.19 0.0 0.0 82.44 Detail
42 LUAD cuproptosis MTBP MDM2 binding protein 4.8 6.37 0.41 0.0 0.0 82.19 Detail
43 LUAD cuproptosis PFKP phosphofructokinase, platelet 9.39 11.25 0.26 0.0 0.0 81.99 Detail
44 LUAD cuproptosis SNCA synuclein alpha 7.14 5.32 -0.42 0.0 0.0 81.66 Detail
45 LUAD cuproptosis CCDC137 coiled-coil domain containing 137 8.32 9.26 0.16 0.0 0.0 81.65 Detail
46 LUAD cuproptosis DTYMK deoxythymidylate kinase 7.86 9.15 0.22 0.0 0.0 81.43 Detail
47 LUAD cuproptosis MTFR1 mitochondrial fission regulator 1 8.31 9.42 0.18 0.0 0.0 81.09 Detail
48 LUAD cuproptosis SLC31A2 solute carrier family 31 member 2 10.16 8.71 -0.22 0.0 0.0 80.86 Detail
49 LUAD cuproptosis MRPL30 mitochondrial ribosomal protein L30 8.98 9.64 0.1 0.0 0.0 79.91 Detail
50 LUAD cuproptosis MARS2 methionyl-tRNA synthetase 2, mitochondrial 6.8 7.72 0.18 0.0 0.0 78.86 Detail
51 LUAD cuproptosis NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 10.42 11.0 0.08 0.0 0.0 78.57 Detail
52 LUAD cuproptosis SRP54 signal recognition particle 54 9.97 10.63 0.09 0.0 0.0 78.18 Detail
53 LUAD cuproptosis MRPL15 mitochondrial ribosomal protein L15 9.0 10.01 0.15 0.0 0.0 78.16 Detail
54 LUAD cuproptosis IMP4 IMP U3 small nucleolar ribonucleoprotein 4 8.75 9.5 0.12 0.0 0.0 76.02 Detail
55 LUAD cuproptosis FADD Fas associated via death domain 8.62 9.37 0.12 0.0 0.0 75.28 Detail
56 LUAD cuproptosis PLOD1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 10.98 11.77 0.1 0.0 0.0 75.27 Detail
57 LUAD cuproptosis MRPL36 mitochondrial ribosomal protein L36 7.48 8.52 0.19 0.0 0.0 75.05 Detail
58 LUAD cuproptosis MRPL17 mitochondrial ribosomal protein L17 9.26 10.12 0.13 0.0 0.0 74.96 Detail
59 LUAD cuproptosis MDH2 malate dehydrogenase 2 11.14 11.88 0.09 0.0 0.0 74.86 Detail
60 LUAD cuproptosis MRPS30 mitochondrial ribosomal protein S30 8.16 8.89 0.12 0.0 0.0 74.65 Detail
61 LUAD cuproptosis GTPBP4 GTP binding protein 4 9.38 10.18 0.12 0.0 0.0 74.4 Detail
62 LUAD cuproptosis STARD7 StAR related lipid transfer domain containing 7 12.33 11.8 -0.06 0.0 0.0 74.19 Detail
63 LUAD cuproptosis CDK5RAP1 CDK5 regulatory subunit associated protein 1 8.59 9.16 0.09 0.0 0.0 74.09 Detail
64 LUAD cuproptosis VPS45 vacuolar protein sorting 45 homolog 9.28 9.84 0.08 0.0 0.0 73.47 Detail
65 LUAD cuproptosis AQP1 aquaporin 1 (Colton blood group) 14.99 12.4 -0.27 0.0 0.0 73.32 Detail
66 LUAD cuproptosis MT1M metallothionein 1M 7.84 4.96 -0.66 0.0 0.0 73.05 Detail
67 LUAD cuproptosis TPK1 thiamin pyrophosphokinase 1 7.5 6.29 -0.25 0.0 0.0 72.76 Detail
68 LUAD cuproptosis MRPS33 mitochondrial ribosomal protein S33 8.51 9.38 0.14 0.0 0.0 72.38 Detail
69 LUAD cuproptosis TOP1MT DNA topoisomerase I mitochondrial 8.34 9.2 0.14 0.0 0.0 71.88 Detail
70 LUAD cuproptosis CP ceruloplasmin 9.21 12.26 0.41 0.0 0.0 71.8 Detail
71 LUAD cuproptosis FKBP4 FKBP prolyl isomerase 4 10.15 11.09 0.13 0.0 0.0 71.44 Detail
72 LUAD cuproptosis EIF3I eukaryotic translation initiation factor 3 subunit I 11.3 11.95 0.08 0.0 0.0 71.32 Detail
73 LUAD cuproptosis CHMP4B charged multivesicular body protein 4B 11.54 12.07 0.06 0.0 0.0 71.31 Detail
74 LUAD cuproptosis MRPS5 mitochondrial ribosomal protein S5 9.5 10.01 0.07 0.0 0.0 70.91 Detail
75 LUAD cuproptosis NDUFS6 NADH:ubiquinone oxidoreductase subunit S6 9.26 10.15 0.13 0.0 0.0 70.53 Detail
76 LUAD cuproptosis RHOV ras homolog family member V 5.09 7.98 0.65 0.0 0.0 70.17 Detail
77 LUAD cuproptosis NFE2L2 NFE2 like bZIP transcription factor 2 11.86 11.33 -0.07 0.0 0.0 70.11 Detail
78 LUAD cuproptosis TAF4 TATA-box binding protein associated factor 4 8.35 8.96 0.1 0.0 0.0 70.07 Detail
79 LUAD cuproptosis UBAP2L ubiquitin associated protein 2 like 11.26 11.82 0.07 0.0 0.0 69.88 Detail
80 LUAD cuproptosis CIAO1 cytosolic iron-sulfur assembly component 1 10.63 10.93 0.04 0.0 0.0 69.6 Detail
81 LUAD cuproptosis PDZD4 PDZ domain containing 4 7.14 5.34 -0.42 0.0 0.0 69.42 Detail
82 LUAD cuproptosis SOD3 superoxide dismutase 3 10.67 9.33 -0.19 0.0 0.0 69.3 Detail
83 LUAD cuproptosis MRPS16 mitochondrial ribosomal protein S16 10.18 10.77 0.08 0.0 0.0 69.0 Detail
84 LUAD cuproptosis SSBP1 single stranded DNA binding protein 1 9.47 10.14 0.1 0.0 0.0 68.92 Detail
85 LUAD cuproptosis HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 13.22 13.66 0.05 0.0 0.0 68.73 Detail
86 LUAD cuproptosis MRPS12 mitochondrial ribosomal protein S12 8.36 9.34 0.16 0.0 0.0 68.51 Detail
87 LUAD cuproptosis GCSH glycine cleavage system protein H 1.91 3.69 0.95 0.0 0.0 68.02 Detail
88 LUAD cuproptosis MRPS23 mitochondrial ribosomal protein S23 9.2 10.05 0.13 0.0 0.0 67.88 Detail
89 LUAD cuproptosis MRPL13 mitochondrial ribosomal protein L13 8.56 9.45 0.14 0.0 0.0 67.84 Detail
90 LUAD cuproptosis ABCE1 ATP binding cassette subfamily E member 1 9.95 10.54 0.08 0.0 0.0 67.65 Detail
91 LUAD cuproptosis PRKDC protein kinase, DNA-activated, catalytic subunit 11.09 11.98 0.11 0.0 0.0 67.65 Detail
92 LUAD cuproptosis CYC1 cytochrome c1 10.16 11.06 0.12 0.0 0.0 67.44 Detail
93 LUAD cuproptosis ZNF341 zinc finger protein 341 6.93 7.73 0.16 0.0 0.0 67.03 Detail
94 LUAD cuproptosis DLG3 discs large MAGUK scaffold protein 3 9.69 10.37 0.1 0.0 0.0 66.85 Detail
95 LUAD cuproptosis C6orf136 chromosome 6 open reading frame 136 7.47 8.13 0.12 0.0 0.0 66.4 Detail
96 LUAD cuproptosis SLC7A11 solute carrier family 7 member 11 6.18 8.61 0.48 0.0 0.0 66.31 Detail
97 LUAD cuproptosis BACE1 beta-secretase 1 10.36 9.65 -0.1 0.0 0.0 66.11 Detail
98 LUAD cuproptosis MFF mitochondrial fission factor 9.68 10.18 0.07 0.0 0.0 66.09 Detail
99 LUAD cuproptosis RANGAP1 Ran GTPase activating protein 1 10.34 10.95 0.08 0.0 0.0 65.94 Detail
100 LUAD cuproptosis MAD2L2 mitotic arrest deficient 2 like 2 8.18 9.07 0.15 0.0 0.0 65.79 Detail
101 LUAD cuproptosis BRCA1 BRCA1 DNA repair associated 6.88 8.08 0.23 0.0 0.0 65.63 Detail
102 LUAD cuproptosis SARS2 seryl-tRNA synthetase 2, mitochondrial 7.88 8.59 0.13 0.0 0.0 65.44 Detail
103 LUAD cuproptosis YARS2 tyrosyl-tRNA synthetase 2 7.81 8.44 0.11 0.0 0.0 65.43 Detail
104 LUAD cuproptosis PDE3B phosphodiesterase 3B 9.21 7.84 -0.23 0.0 0.0 65.23 Detail
105 LUAD cuproptosis TIMM9 translocase of inner mitochondrial membrane 9 8.18 8.86 0.12 0.0 0.0 65.13 Detail
106 LUAD cuproptosis CNN1 calponin 1 9.32 7.59 -0.3 0.0 0.0 65.1 Detail
107 LUAD cuproptosis RTEL1 regulator of telomere elongation helicase 1 7.94 8.9 0.17 0.0 0.0 64.82 Detail
108 LUAD cuproptosis MRPL2 mitochondrial ribosomal protein L2 8.49 9.1 0.1 0.0 0.0 64.56 Detail
109 LUAD cuproptosis RSL1D1 ribosomal L1 domain containing 1 11.25 11.78 0.07 0.0 0.0 64.49 Detail
110 LUAD cuproptosis PSMB5 proteasome 20S subunit beta 5 10.49 11.19 0.09 0.0 0.0 64.35 Detail
111 LUAD cuproptosis PRNP prion protein (Kanno blood group) 11.7 10.95 -0.09 0.0 0.0 64.12 Detail
112 LUAD cuproptosis AOC2 amine oxidase copper containing 2 5.25 4.14 -0.34 0.0 0.0 64.02 Detail
113 LUAD cuproptosis COX18 cytochrome c oxidase assembly factor COX18 8.27 8.85 0.1 0.0 0.0 63.98 Detail
114 LUAD cuproptosis HARS2 histidyl-tRNA synthetase 2, mitochondrial 8.96 9.44 0.08 0.0 0.0 63.7 Detail
115 LUAD cuproptosis MRPL21 mitochondrial ribosomal protein L21 8.4 9.11 0.12 0.0 0.0 63.69 Detail
116 LUAD cuproptosis CENPW centromere protein W 5.52 6.88 0.32 0.0 0.0 63.09 Detail
117 LUAD cuproptosis CCS copper chaperone for superoxide dismutase 8.55 9.11 0.09 0.0 0.0 62.82 Detail
118 LUAD cuproptosis ACP1 acid phosphatase 1 10.34 10.83 0.07 0.0 0.0 62.79 Detail
119 LUAD cuproptosis MECR mitochondrial trans-2-enoyl-CoA reductase 7.99 8.47 0.08 0.0 0.0 62.52 Detail
120 LUAD cuproptosis TFAM transcription factor A, mitochondrial 8.59 9.2 0.1 0.0 0.0 62.38 Detail
121 LUAD cuproptosis MRPL55 mitochondrial ribosomal protein L55 8.53 9.25 0.12 0.0 0.0 62.35 Detail
122 LUAD cuproptosis HSPA9 heat shock protein family A (Hsp70) member 9 11.73 12.27 0.06 0.0 0.0 62.06 Detail
123 LUAD cuproptosis IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma 9.65 10.14 0.07 0.0 0.0 61.98 Detail
124 LUAD cuproptosis NNAT neuronatin 4.41 3.38 -0.38 0.0 0.0 61.96 Detail
125 LUAD cuproptosis MRPL44 mitochondrial ribosomal protein L44 8.83 9.33 0.08 0.0 0.0 61.87 Detail
126 LUAD cuproptosis RPUSD4 RNA pseudouridine synthase D4 8.36 8.84 0.08 0.0 0.0 61.71 Detail
127 LUAD cuproptosis SDHC succinate dehydrogenase complex subunit C 10.53 11.09 0.07 0.0 0.0 61.7 Detail
128 LUAD cuproptosis POLE DNA polymerase epsilon, catalytic subunit 8.68 9.54 0.14 0.0 0.0 61.66 Detail
129 LUAD cuproptosis SDHA succinate dehydrogenase complex flavoprotein subunit A 10.79 11.32 0.07 0.0 0.0 61.37 Detail
130 LUAD cuproptosis NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 10.69 11.13 0.06 0.0 0.0 60.91 Detail
131 LUAD cuproptosis MRRF mitochondrial ribosome recycling factor 8.15 8.67 0.09 0.0 0.0 60.4 Detail
132 LUAD cuproptosis VARS2 valyl-tRNA synthetase 2, mitochondrial 9.04 9.63 0.09 0.0 0.0 60.3 Detail
133 LUAD cuproptosis ABCB4 ATP binding cassette subfamily B member 4 2.77 4.32 0.64 0.0 0.0 59.57 Detail
134 LUAD cuproptosis MRPS21 mitochondrial ribosomal protein S21 9.49 10.19 0.1 0.0 0.0 59.4 Detail
135 LUAD cuproptosis RAD9A RAD9 checkpoint clamp component A 7.5 8.2 0.13 0.0 0.0 59.32 Detail
136 LUAD cuproptosis MPI mannose phosphate isomerase 8.85 9.33 0.08 0.0 0.0 59.19 Detail
137 LUAD cuproptosis POLR2B RNA polymerase II subunit B 10.64 11.0 0.05 0.0 0.0 59.05 Detail
138 LUAD cuproptosis MRPL52 mitochondrial ribosomal protein L52 8.6 9.35 0.12 0.0 0.0 58.78 Detail
139 LUAD cuproptosis DHX15 DEAH-box helicase 15 10.99 11.37 0.05 0.0 0.0 58.7 Detail
140 LUAD cuproptosis MUC20 mucin 20, cell surface associated 8.49 10.14 0.26 0.0 0.0 58.7 Detail
141 LUAD cuproptosis RRN3 RRN3 homolog, RNA polymerase I transcription factor 9.71 10.1 0.06 0.0 0.0 58.25 Detail
142 LUAD cuproptosis TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 8.81 9.3 0.08 0.0 0.0 58.12 Detail
143 LUAD cuproptosis NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 9.93 10.41 0.07 0.0 0.0 58.01 Detail
144 LUAD cuproptosis MRPL51 mitochondrial ribosomal protein L51 9.98 10.56 0.08 0.0 0.0 57.95 Detail
145 LUAD cuproptosis MTG1 mitochondrial ribosome associated GTPase 1 8.25 8.9 0.11 0.0 0.0 57.92 Detail
146 LUAD cuproptosis HAUS5 HAUS augmin like complex subunit 5 7.82 8.54 0.13 0.0 0.0 57.91 Detail
147 LUAD cuproptosis ISCA2 iron-sulfur cluster assembly 2 8.06 8.73 0.11 0.0 0.0 57.69 Detail
148 LUAD cuproptosis PARK7 Parkinsonism associated deglycase 11.33 11.8 0.06 0.0 0.0 57.36 Detail
149 LUAD cuproptosis SLC16A6 solute carrier family 16 member 6 6.43 5.04 -0.35 0.0 0.0 57.22 Detail
150 LUAD cuproptosis CHCHD1 coiled-coil-helix-coiled-coil-helix domain containing 1 8.76 9.34 0.09 0.0 0.0 57.1 Detail
151 LUAD cuproptosis BARX1 BARX homeobox 1 0.9 4.48 2.32 0.0 0.0 56.94 Detail
152 LUAD cuproptosis CAPRIN1 cell cycle associated protein 1 12.03 12.41 0.04 0.0 0.0 56.59 Detail
153 LUAD cuproptosis LOXL2 lysyl oxidase like 2 8.18 9.64 0.24 0.0 0.0 56.58 Detail
154 LUAD cuproptosis IDH1 isocitrate dehydrogenase (NADP(+)) 1 11.06 11.85 0.1 0.0 0.0 56.18 Detail
155 LUAD cuproptosis PPIE peptidylprolyl isomerase E 9.32 9.8 0.07 0.0 0.0 55.93 Detail
156 LUAD cuproptosis HSF1 heat shock transcription factor 1 10.37 10.86 0.07 0.0 0.0 55.17 Detail
157 LUAD cuproptosis POLD1 DNA polymerase delta 1, catalytic subunit 8.74 9.29 0.09 0.0 0.0 54.81 Detail
158 LUAD cuproptosis HNRNPU heterogeneous nuclear ribonucleoprotein U 12.91 13.28 0.04 0.0 0.0 54.78 Detail
159 LUAD cuproptosis DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 9.66 10.04 0.06 0.0 0.0 54.77 Detail
160 LUAD cuproptosis ARF1 ADP ribosylation factor 1 13.27 13.69 0.05 0.0 0.0 54.64 Detail
161 LUAD cuproptosis PURG purine rich element binding protein G 2.56 1.59 -0.68 0.0 0.0 54.64 Detail
162 LUAD cuproptosis MCM5 minichromosome maintenance complex component 5 9.51 10.12 0.09 0.0 0.0 54.48 Detail
163 LUAD cuproptosis MRPS7 mitochondrial ribosomal protein S7 9.9 10.4 0.07 0.0 0.0 54.45 Detail
164 LUAD cuproptosis HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 9.69 10.24 0.08 0.0 0.0 54.43 Detail
165 LUAD cuproptosis NDUFB4 NADH:ubiquinone oxidoreductase subunit B4 10.14 10.67 0.07 0.0 0.0 54.22 Detail
166 LUAD cuproptosis NFKBIA NFKB inhibitor alpha 12.93 11.98 -0.11 0.0 0.0 54.07 Detail
167 LUAD cuproptosis NDUFAB1 NADH:ubiquinone oxidoreductase subunit AB1 9.37 9.89 0.08 0.0 0.0 53.85 Detail
168 LUAD cuproptosis TKT transketolase 12.64 13.37 0.08 0.0 0.0 53.84 Detail
169 LUAD cuproptosis MRPS14 mitochondrial ribosomal protein S14 8.2 8.64 0.08 0.0 0.0 53.7 Detail
170 LUAD cuproptosis PGK1 phosphoglycerate kinase 1 12.86 13.58 0.08 0.0 0.0 53.15 Detail
171 LUAD cuproptosis GGPS1 geranylgeranyl diphosphate synthase 1 9.45 9.85 0.06 0.0 0.0 52.96 Detail
172 LUAD cuproptosis CCDC28B coiled-coil domain containing 28B 5.31 6.23 0.23 0.0 0.0 52.81 Detail
173 LUAD cuproptosis CYP2D6 cytochrome P450 family 2 subfamily D member 6 2.6 4.53 0.8 0.0 0.0 52.75 Detail
174 LUAD cuproptosis SLC30A7 solute carrier family 30 member 7 9.59 10.01 0.06 0.0 0.0 52.51 Detail
175 LUAD cuproptosis NDUFB11 NADH:ubiquinone oxidoreductase subunit B11 10.13 10.69 0.08 0.0 0.0 52.45 Detail
176 LUAD cuproptosis SLFN11 schlafen family member 11 10.83 9.94 -0.12 0.0 0.0 52.37 Detail
177 LUAD cuproptosis SDSL serine dehydratase like 7.24 8.1 0.16 0.0 0.0 52.24 Detail
178 LUAD cuproptosis LONP1 lon peptidase 1, mitochondrial 10.35 10.77 0.06 0.0 0.0 51.2 Detail
179 LUAD cuproptosis RPLP0 ribosomal protein lateral stalk subunit P0 13.75 14.44 0.07 0.0 0.0 51.05 Detail
180 LUAD cuproptosis CDKN2A cyclin dependent kinase inhibitor 2A 5.09 7.24 0.51 0.0 0.0 51.03 Detail
181 LUAD cuproptosis MRPS2 mitochondrial ribosomal protein S2 9.12 9.59 0.07 0.0 0.0 50.84 Detail
182 LUAD cuproptosis PGP phosphoglycolate phosphatase 8.26 8.79 0.09 0.0 0.0 50.71 Detail
183 LUAD cuproptosis SNAPIN SNAP associated protein 9.1 9.57 0.07 0.0 0.0 50.62 Detail
184 LUAD cuproptosis ISCU iron-sulfur cluster assembly enzyme 10.89 10.49 -0.05 0.0 0.0 50.33 Detail
185 LUAD cuproptosis CD274 CD274 molecule 7.31 6.06 -0.27 0.0 0.0 50.27 Detail
186 LUAD cuproptosis NDOR1 NADPH dependent diflavin oxidoreductase 1 8.77 9.3 0.08 0.0 0.0 50.19 Detail
187 LUAD cuproptosis CEPT1 choline/ethanolamine phosphotransferase 1 9.49 9.08 -0.06 0.0 0.0 50.14 Detail
188 LUAD cuproptosis SLC33A1 solute carrier family 33 member 1 8.96 9.4 0.07 0.0 0.0 50.12 Detail
189 LUAD cuproptosis EIF4G1 eukaryotic translation initiation factor 4 gamma 1 12.72 13.15 0.05 0.0 0.0 49.77 Detail
190 LUAD cuproptosis RAD23B RAD23 homolog B, nucleotide excision repair protein 11.56 11.93 0.04 0.0 0.0 49.57 Detail
191 LUAD cuproptosis STEAP3 STEAP3 metalloreductase 9.86 10.59 0.1 0.0 0.0 49.55 Detail
192 LUAD cuproptosis C1QBP complement C1q binding protein 9.8 10.44 0.09 0.0 0.0 49.47 Detail
193 LUAD cuproptosis COX6B1 cytochrome c oxidase subunit 6B1 10.86 11.47 0.08 0.0 0.0 49.18 Detail
194 LUAD cuproptosis AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 9.45 9.79 0.05 0.0 0.0 48.88 Detail
195 LUAD cuproptosis FGD6 FYVE, RhoGEF and PH domain containing 6 9.27 9.98 0.11 0.0 0.0 48.66 Detail
196 LUAD cuproptosis SPATA13 spermatogenesis associated 13 9.1 8.28 -0.14 0.0 0.0 47.88 Detail
197 LUAD cuproptosis CYP1A1 cytochrome P450 family 1 subfamily A member 1 3.35 1.42 -1.24 0.0 0.0 47.55 Detail
198 LUAD cuproptosis NUBP2 NUBP iron-sulfur cluster assembly factor 2, cytosolic 9.45 9.93 0.07 0.0 0.0 47.13 Detail
199 LUAD cuproptosis MRPS18A mitochondrial ribosomal protein S18A 9.13 9.61 0.07 0.0 0.0 46.9 Detail
200 LUAD cuproptosis MT1A metallothionein 1A 5.36 3.29 -0.7 0.0 0.0 46.77 Detail
201 LUAD cuproptosis ATL2 atlastin GTPase 2 10.13 10.69 0.08 0.0 0.0 46.49 Detail
202 LUAD cuproptosis STEAP2 STEAP2 metalloreductase 8.0 9.04 0.18 0.0 0.0 46.09 Detail
203 LUAD cuproptosis ULK1 unc-51 like autophagy activating kinase 1 9.78 10.3 0.07 0.0 0.0 45.7 Detail
204 LUAD cuproptosis DAXX death domain associated protein 10.12 10.4 0.04 0.0 0.0 45.47 Detail
205 LUAD cuproptosis CYCS cytochrome c, somatic 10.81 11.4 0.08 0.0 0.0 45.19 Detail
206 LUAD cuproptosis MBTPS2 membrane bound transcription factor peptidase, site 2 8.74 9.13 0.06 0.0 0.0 44.61 Detail
207 LUAD cuproptosis LACTB2 lactamase beta 2 8.57 9.27 0.11 0.0 0.0 44.43 Detail
208 LUAD cuproptosis OXA1L OXA1L mitochondrial inner membrane protein 10.73 11.1 0.05 0.0 0.0 44.38 Detail
209 LUAD cuproptosis KIDINS220 kinase D interacting substrate 220 11.34 10.89 -0.06 0.0 0.0 44.35 Detail
210 LUAD cuproptosis DLAT dihydrolipoamide S-acetyltransferase 9.76 10.12 0.05 0.0 0.0 44.33 Detail
211 LUAD cuproptosis SOD1 superoxide dismutase 1 11.15 11.62 0.06 0.0 0.0 44.27 Detail
212 LUAD cuproptosis CISD1 CDGSH iron sulfur domain 1 8.27 8.73 0.08 0.0 0.0 44.21 Detail
213 LUAD cuproptosis PSMA6 proteasome 20S subunit alpha 6 11.05 11.67 0.08 0.0 0.0 43.93 Detail
214 LUAD cuproptosis GCLM glutamate-cysteine ligase modifier subunit 8.27 9.13 0.14 0.0 0.0 43.88 Detail
215 LUAD cuproptosis ACLY ATP citrate lyase 11.4 11.79 0.05 0.0 0.0 43.72 Detail
216 LUAD cuproptosis ALAS1 5'-aminolevulinate synthase 1 10.99 10.57 -0.06 0.0 0.0 43.51 Detail
217 LUAD cuproptosis NDUFB10 NADH:ubiquinone oxidoreductase subunit B10 9.89 10.3 0.06 0.0 0.0 43.39 Detail
218 LUAD cuproptosis DPYD dihydropyrimidine dehydrogenase 10.6 9.7 -0.13 0.0 0.0 43.34 Detail
219 LUAD cuproptosis ISG15 ISG15 ubiquitin like modifier 9.24 10.3 0.16 0.0 0.0 43.13 Detail
220 LUAD cuproptosis UBE2D1 ubiquitin conjugating enzyme E2 D1 8.81 9.21 0.06 0.0 0.0 42.37 Detail
221 LUAD cuproptosis TRRAP transformation/transcription domain associated protein 10.38 10.88 0.07 0.0 0.0 42.27 Detail
222 LUAD cuproptosis PCGF6 polycomb group ring finger 6 7.02 7.4 0.08 0.0 0.0 42.13 Detail
223 LUAD cuproptosis BUD31 BUD31 homolog 9.88 10.34 0.07 0.0 0.0 42.02 Detail
224 LUAD cuproptosis MFN2 mitofusin 2 11.5 11.21 -0.04 0.0 0.0 41.89 Detail
225 LUAD cuproptosis MRPS9 mitochondrial ribosomal protein S9 8.55 8.89 0.06 0.0 0.0 41.88 Detail
226 LUAD cuproptosis NDUFB9 NADH:ubiquinone oxidoreductase subunit B9 10.76 11.35 0.08 0.0 0.0 41.79 Detail
227 LUAD cuproptosis CIAPIN1 cytokine induced apoptosis inhibitor 1 9.53 9.88 0.05 0.0 0.0 41.74 Detail
228 LUAD cuproptosis TLR3 toll like receptor 3 8.52 7.59 -0.17 0.0 0.0 41.73 Detail
229 LUAD cuproptosis COQ7 coenzyme Q7, hydroxylase 8.74 8.39 -0.06 0.0 0.0 41.72 Detail
230 LUAD cuproptosis HEPHL1 hephaestin like 1 0.54 1.67 1.63 0.0 0.0 41.7 Detail
231 LUAD cuproptosis GCLC glutamate-cysteine ligase catalytic subunit 8.87 10.11 0.19 0.0 0.0 41.65 Detail
232 LUAD cuproptosis FZD8 frizzled class receptor 8 8.62 7.85 -0.13 0.0 0.0 41.6 Detail
233 LUAD cuproptosis ANKRD49 ankyrin repeat domain 49 7.75 8.18 0.08 0.0 0.0 41.56 Detail
234 LUAD cuproptosis MRPS25 mitochondrial ribosomal protein S25 9.56 10.12 0.08 0.0 0.0 41.21 Detail
235 LUAD cuproptosis RPUSD3 RNA pseudouridine synthase D3 8.4 8.77 0.06 0.0 0.0 40.99 Detail
236 LUAD cuproptosis ELF3 E74 like ETS transcription factor 3 11.92 12.68 0.09 0.0 0.0 40.86 Detail
237 LUAD cuproptosis SUPT16H SPT16 homolog, facilitates chromatin remodeling subunit 10.99 11.32 0.04 0.0 0.0 40.73 Detail
238 LUAD cuproptosis NDUFA9 NADH:ubiquinone oxidoreductase subunit A9 9.73 10.17 0.06 0.0 0.0 40.19 Detail
239 LUAD cuproptosis FAS Fas cell surface death receptor 9.5 8.68 -0.13 0.0 0.0 40.02 Detail
240 LUAD cuproptosis MRPS11 mitochondrial ribosomal protein S11 8.46 8.86 0.07 0.0 0.0 39.93 Detail
241 LUAD cuproptosis MRPL53 mitochondrial ribosomal protein L53 8.9 9.32 0.07 0.0 0.0 39.45 Detail
242 LUAD cuproptosis CS citrate synthase 11.51 11.84 0.04 0.0 0.0 39.26 Detail
243 LUAD cuproptosis SCO1 synthesis of cytochrome C oxidase 1 8.31 8.63 0.05 0.0 0.0 38.91 Detail
244 LUAD cuproptosis RPS19 ribosomal protein S19 13.16 13.76 0.06 0.0 0.0 38.81 Detail
245 LUAD cuproptosis RB1 RB transcriptional corepressor 1 10.25 9.83 -0.06 0.0 0.0 38.67 Detail
246 LUAD cuproptosis PTCD3 pentatricopeptide repeat domain 3 9.66 9.97 0.05 0.0 0.0 38.4 Detail
247 LUAD cuproptosis DOT1L DOT1 like histone lysine methyltransferase 9.89 9.32 -0.09 0.0 0.0 38.18 Detail
248 LUAD cuproptosis CMC1 C-X9-C motif containing 1 7.03 7.47 0.09 0.0 0.0 38.18 Detail
249 LUAD cuproptosis OGDHL oxoglutarate dehydrogenase L 1.73 3.71 1.1 0.0 0.0 38.14 Detail
250 LUAD cuproptosis GFM1 G elongation factor mitochondrial 1 9.72 10.03 0.05 0.0 0.0 37.84 Detail
251 LUAD cuproptosis STEAP4 STEAP4 metalloreductase 12.53 11.29 -0.15 0.0 0.0 37.78 Detail
252 LUAD cuproptosis CLEC11A C-type lectin domain containing 11A 6.92 7.63 0.14 0.0 0.0 37.65 Detail
253 LUAD cuproptosis DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 11.74 11.42 -0.04 0.0 0.0 37.31 Detail
254 LUAD cuproptosis UQCRC1 ubiquinol-cytochrome c reductase core protein 1 11.09 11.43 0.04 0.0 0.0 37.17 Detail
255 LUAD cuproptosis MRPL41 mitochondrial ribosomal protein L41 8.53 9.03 0.08 0.0 0.0 36.92 Detail
256 LUAD cuproptosis NAPA NSF attachment protein alpha 11.52 11.22 -0.04 0.0 0.0 36.88 Detail
257 LUAD cuproptosis MRPL16 mitochondrial ribosomal protein L16 9.09 9.4 0.05 0.0 0.0 36.53 Detail
258 LUAD cuproptosis NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 10.0 10.35 0.05 0.0 0.0 36.53 Detail
259 LUAD cuproptosis ZBP1 Z-DNA binding protein 1 5.18 6.1 0.24 0.0 0.0 36.44 Detail
260 LUAD cuproptosis ISCA1 iron-sulfur cluster assembly 1 9.41 9.08 -0.05 0.0 0.0 36.36 Detail
261 LUAD cuproptosis MT1H metallothionein 1H 1.4 2.82 1.01 0.0 0.0 36.11 Detail
262 LUAD cuproptosis SURF6 surfeit 6 9.04 9.4 0.06 0.0 0.0 36.08 Detail
263 LUAD cuproptosis COPZ1 COPI coat complex subunit zeta 1 11.61 11.91 0.04 0.0 0.0 35.76 Detail
264 LUAD cuproptosis TP53 tumor protein p53 9.83 10.21 0.06 0.0 0.0 35.7 Detail
265 LUAD cuproptosis NLRP3 NLR family pyrin domain containing 3 7.34 6.45 -0.18 0.0 0.0 35.6 Detail
266 LUAD cuproptosis SCO2 synthesis of cytochrome C oxidase 2 8.81 9.29 0.08 0.0 0.0 35.54 Detail
267 LUAD cuproptosis GATC glutamyl-tRNA amidotransferase subunit C 4.76 5.23 0.14 0.0 0.0 35.48 Detail
268 LUAD cuproptosis SDHAF2 succinate dehydrogenase complex assembly factor 2 9.21 9.49 0.04 0.0 0.0 35.44 Detail
269 LUAD cuproptosis NUP133 nucleoporin 133 9.87 10.13 0.04 0.0 0.0 35.3 Detail
270 LUAD cuproptosis NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 10.23 10.64 0.06 0.0 0.0 35.19 Detail
271 LUAD cuproptosis CCDC115 coiled-coil domain containing 115 10.16 9.88 -0.04 0.0 0.0 34.93 Detail
272 LUAD cuproptosis TSC22D2 TSC22 domain family member 2 9.51 9.07 -0.07 0.0 0.0 34.93 Detail
273 LUAD cuproptosis MTF1 metal regulatory transcription factor 1 9.29 8.92 -0.06 0.0 0.0 34.8 Detail
274 LUAD cuproptosis UBA2 ubiquitin like modifier activating enzyme 2 10.71 11.1 0.05 0.0 0.0 34.7 Detail
275 LUAD cuproptosis RUVBL2 RuvB like AAA ATPase 2 10.11 10.51 0.06 0.0 0.0 34.22 Detail
276 LUAD cuproptosis LARS2 leucyl-tRNA synthetase 2, mitochondrial 8.46 8.71 0.04 0.0 0.0 33.83 Detail
277 LUAD cuproptosis NTHL1 nth like DNA glycosylase 1 8.15 8.65 0.08 0.0 0.0 33.83 Detail
278 LUAD cuproptosis SEC14L2 SEC14 like lipid binding 2 6.92 7.59 0.13 0.0 0.0 33.73 Detail
279 LUAD cuproptosis COPS5 COP9 signalosome subunit 5 9.72 10.08 0.05 0.0 0.0 33.08 Detail
280 LUAD cuproptosis RPL19 ribosomal protein L19 13.86 14.23 0.04 0.0 0.0 32.95 Detail
281 LUAD cuproptosis GADD45GIP1 GADD45G interacting protein 1 9.05 9.47 0.07 0.0 0.0 32.84 Detail
282 LUAD cuproptosis HSCB HscB mitochondrial iron-sulfur cluster cochaperone 7.41 7.82 0.08 0.0 0.0 32.53 Detail
283 LUAD cuproptosis MAP1LC3A microtubule associated protein 1 light chain 3 alpha 8.71 8.05 -0.11 0.0 0.0 32.43 Detail
284 LUAD cuproptosis PRDX1 peroxiredoxin 1 12.56 13.06 0.06 0.0 0.0 32.18 Detail
285 LUAD cuproptosis NRF1 nuclear respiratory factor 1 8.69 8.51 -0.03 0.0 0.0 32.13 Detail
286 LUAD cuproptosis NDUFA8 NADH:ubiquinone oxidoreductase subunit A8 9.18 9.5 0.05 0.0 0.0 31.98 Detail
287 LUAD cuproptosis FDX1 ferredoxin 1 9.59 9.23 -0.05 0.0 0.0 31.65 Detail
288 LUAD cuproptosis BECN1 beclin 1 10.6 10.81 0.03 0.0 0.0 31.09 Detail
289 LUAD cuproptosis ABCB8 ATP binding cassette subfamily B member 8 9.24 9.54 0.05 0.0 0.0 30.99 Detail
290 LUAD cuproptosis HCCS holocytochrome c synthase 8.58 8.86 0.05 0.0 0.0 30.95 Detail
291 LUAD cuproptosis FPGS folylpolyglutamate synthase 9.94 10.28 0.05 0.0 0.0 30.85 Detail
292 LUAD cuproptosis POLR2K RNA polymerase II, I and III subunit K 9.64 10.0 0.05 0.0 0.0 30.5 Detail
293 LUAD cuproptosis MAL2 mal, T cell differentiation protein 2 12.49 12.92 0.05 0.0 0.0 30.21 Detail
294 LUAD cuproptosis PITRM1 pitrilysin metallopeptidase 1 10.47 10.78 0.04 0.0 0.0 30.19 Detail
295 LUAD cuproptosis COX7B cytochrome c oxidase subunit 7B 10.05 10.46 0.06 0.0 0.0 30.02 Detail
296 LUAD cuproptosis RPL27 ribosomal protein L27 12.7 13.19 0.05 0.0 0.0 29.91 Detail
297 LUAD cuproptosis CENPJ centromere protein J 6.9 7.41 0.1 0.0 0.0 29.74 Detail
298 LUAD cuproptosis ZFAT zinc finger and AT-hook domain containing 7.73 8.12 0.07 0.0 0.0 29.74 Detail
299 LUAD cuproptosis CIT citron rho-interacting serine/threonine kinase 9.28 10.42 0.17 0.0 0.0 29.19 Detail
300 LUAD cuproptosis RPL28 ribosomal protein L28 13.08 13.55 0.05 0.0 0.0 29.09 Detail
301 LUAD cuproptosis MCAT malonyl-CoA-acyl carrier protein transacylase 7.9 8.23 0.06 0.0 0.0 28.36 Detail
302 LUAD cuproptosis NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 10.52 10.82 0.04 0.0 0.0 28.31 Detail
303 LUAD cuproptosis UBE2D3 ubiquitin conjugating enzyme E2 D3 12.47 12.26 -0.03 0.0 0.0 28.27 Detail
304 LUAD cuproptosis TAF6L TATA-box binding protein associated factor 6 like 7.75 8.01 0.05 0.0 0.0 27.41 Detail
305 LUAD cuproptosis DBH dopamine beta-hydroxylase 3.63 2.89 -0.33 0.0 0.0 26.74 Detail
306 LUAD cuproptosis PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 9.97 10.23 0.04 0.0 0.0 26.63 Detail
307 LUAD cuproptosis YAP1 Yes1 associated transcriptional regulator 11.87 11.51 -0.04 0.0 0.0 26.61 Detail
308 LUAD cuproptosis ATOX1 antioxidant 1 copper chaperone 9.03 9.36 0.05 0.0 0.0 26.33 Detail
309 LUAD cuproptosis HEPH hephaestin 8.8 8.21 -0.1 0.0 0.0 26.19 Detail
310 LUAD cuproptosis NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 10.08 10.4 0.05 0.0 0.0 26.1 Detail
311 LUAD cuproptosis MRPS18B mitochondrial ribosomal protein S18B 10.18 10.49 0.04 0.0 0.0 26.07 Detail
312 LUAD cuproptosis PDHX pyruvate dehydrogenase complex component X 8.94 9.22 0.05 0.0 0.0 25.77 Detail
313 LUAD cuproptosis TADA2A transcriptional adaptor 2A 7.19 7.47 0.06 0.0 0.0 25.53 Detail
314 LUAD cuproptosis POT1 protection of telomeres 1 8.58 8.87 0.05 0.0 0.0 25.12 Detail
315 LUAD cuproptosis LIAS lipoic acid synthetase 6.98 7.34 0.07 0.0 0.0 25.09 Detail
316 LUAD cuproptosis ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 7.97 8.24 0.05 0.0 0.0 24.67 Detail
317 LUAD cuproptosis ANKRD9 ankyrin repeat domain 9 6.22 6.73 0.11 0.0 0.0 24.62 Detail
318 LUAD cuproptosis PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 10.32 10.08 -0.03 0.0 0.0 24.32 Detail
319 LUAD cuproptosis XIAP X-linked inhibitor of apoptosis 10.52 10.75 0.03 0.0 0.0 24.29 Detail
320 LUAD cuproptosis FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial 8.02 7.76 -0.05 0.0 0.0 24.05 Detail
321 LUAD cuproptosis MT1E metallothionein 1E 9.85 8.95 -0.14 0.0 0.0 23.73 Detail
322 LUAD cuproptosis PPA2 inorganic pyrophosphatase 2 9.78 10.08 0.04 0.0 0.0 23.58 Detail
323 LUAD cuproptosis GLRX5 glutaredoxin 5 9.31 9.56 0.04 0.0 0.0 23.22 Detail
324 LUAD cuproptosis MMGT1 membrane magnesium transporter 1 10.12 9.86 -0.04 0.0 0.0 22.53 Detail
325 LUAD cuproptosis INSL4 insulin like 4 0.14 1.75 3.67 0.0 0.0 22.3 Detail
326 LUAD cuproptosis DNM1L dynamin 1 like 9.99 10.25 0.04 0.0 0.0 22.15 Detail
327 LUAD cuproptosis REXO2 RNA exonuclease 2 9.6 9.84 0.04 0.0 0.0 21.23 Detail
328 LUAD cuproptosis RMND1 required for meiotic nuclear division 1 homolog 8.14 8.42 0.05 0.0 0.0 20.72 Detail
329 LUAD cuproptosis COX7C cytochrome c oxidase subunit 7C 11.29 11.59 0.04 0.0 0.0 20.23 Detail
330 LUAD cuproptosis DBR1 debranching RNA lariats 1 8.63 8.46 -0.03 0.0 0.0 20.17 Detail
331 LUAD cuproptosis TNF tumor necrosis factor 5.5 4.76 -0.21 0.0 0.0 20.02 Detail
332 LUAD cuproptosis MAP2K2 mitogen-activated protein kinase kinase 2 10.7 10.9 0.03 0.0 0.0 19.88 Detail
333 LUAD cuproptosis TMEM199 transmembrane protein 199 8.71 8.91 0.03 0.0 0.0 19.76 Detail
334 LUAD cuproptosis SDHB succinate dehydrogenase complex iron sulfur subunit B 10.17 10.37 0.03 0.0 0.0 19.7 Detail
335 LUAD cuproptosis MRPL40 mitochondrial ribosomal protein L40 8.9 9.2 0.05 0.0 0.0 19.58 Detail
336 LUAD cuproptosis IFT81 intraflagellar transport 81 7.99 8.35 0.06 0.0 0.0 19.19 Detail
337 LUAD cuproptosis COX15 cytochrome c oxidase assembly homolog COX15 9.78 9.99 0.03 0.0 0.0 18.59 Detail
338 LUAD cuproptosis CCL20 C-C motif chemokine ligand 20 6.74 7.93 0.23 0.0 0.0 18.53 Detail
339 LUAD cuproptosis IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha 9.97 9.81 -0.02 0.0 0.0 18.51 Detail
340 LUAD cuproptosis SYMPK symplekin scaffold protein 10.66 10.9 0.03 0.0 0.0 18.4 Detail
341 LUAD cuproptosis RPL10A ribosomal protein L10a 12.95 13.28 0.04 0.0 0.0 18.27 Detail
342 LUAD cuproptosis RIPK1 receptor interacting serine/threonine kinase 1 10.14 9.98 -0.02 0.0 0.0 18.04 Detail
343 LUAD cuproptosis SLC30A10 solute carrier family 30 member 10 0.08 0.78 3.33 0.0 0.0 17.91 Detail
344 LUAD cuproptosis MT1F metallothionein 1F 6.32 6.85 0.11 0.0 0.0 17.6 Detail
345 LUAD cuproptosis BCL2 BCL2 apoptosis regulator 8.36 7.93 -0.08 0.0 0.0 17.04 Detail
346 LUAD cuproptosis PRDM10 PR/SET domain 10 7.58 7.77 0.04 0.0 0.0 17.0 Detail
347 LUAD cuproptosis RPS25 ribosomal protein S25 12.66 12.9 0.03 0.0 0.0 16.83 Detail
348 LUAD cuproptosis CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit X 9.12 9.33 0.03 0.0 0.0 16.37 Detail
349 LUAD cuproptosis NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 10.04 10.28 0.03 0.0 0.0 16.17 Detail
350 LUAD cuproptosis RPL7A ribosomal protein L7a 13.37 13.67 0.03 0.0 0.0 16.16 Detail
351 LUAD cuproptosis APP amyloid beta precursor protein 14.09 13.81 -0.03 0.0 0.0 15.74 Detail
352 LUAD cuproptosis TRIM32 tripartite motif containing 32 8.42 8.58 0.03 0.0 0.0 15.44 Detail
353 LUAD cuproptosis FAM96A cytosolic iron-sulfur assembly component 2A 9.47 9.69 0.03 0.0 0.0 15.37 Detail
354 LUAD cuproptosis GPX4 glutathione peroxidase 4 11.54 11.79 0.03 0.0 0.01 15.17 Detail
355 LUAD cuproptosis SLC31A1 solute carrier family 31 member 1 10.8 10.56 -0.03 0.0 0.01 14.87 Detail
356 LUAD cuproptosis HSPA8 heat shock protein family A (Hsp70) member 8 14.23 14.41 0.02 0.0 0.01 14.87 Detail
357 LUAD cuproptosis ABCB7 ATP binding cassette subfamily B member 7 8.55 8.7 0.03 0.0 0.01 14.8 Detail
358 LUAD cuproptosis COX17 cytochrome c oxidase copper chaperone COX17 8.82 9.1 0.04 0.0 0.01 14.45 Detail
359 LUAD cuproptosis WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 8.1 8.32 0.04 0.0 0.01 14.29 Detail
360 LUAD cuproptosis ATP8B1 ATPase phospholipid transporting 8B1 9.94 10.29 0.05 0.0 0.01 14.23 Detail
361 LUAD cuproptosis GFRA3 GDNF family receptor alpha 3 5.08 6.47 0.35 0.0 0.01 14.07 Detail
362 LUAD cuproptosis COX19 cytochrome c oxidase assembly factor COX19 7.96 8.2 0.04 0.01 0.01 13.66 Detail
363 LUAD cuproptosis GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 10.97 11.13 0.02 0.01 0.01 13.6 Detail
364 LUAD cuproptosis MAN2C1 mannosidase alpha class 2C member 1 10.14 9.89 -0.04 0.01 0.01 13.2 Detail
365 LUAD cuproptosis NUBPL NUBP iron-sulfur cluster assembly factor, mitochondrial 7.67 7.91 0.05 0.01 0.01 12.99 Detail
366 LUAD cuproptosis DBT dihydrolipoamide branched chain transacylase E2 9.42 9.24 -0.03 0.01 0.01 12.77 Detail
367 LUAD cuproptosis NDUFB2 NADH:ubiquinone oxidoreductase subunit B2 10.17 10.37 0.03 0.01 0.01 12.63 Detail
368 LUAD cuproptosis NDUFC1 NADH:ubiquinone oxidoreductase subunit C1 9.12 9.33 0.03 0.01 0.01 12.58 Detail
369 LUAD cuproptosis HIST1H3A H3 clustered histone 1 0.3 0.6 1.0 0.01 0.01 12.55 Detail
370 LUAD cuproptosis SOX2 SRY-box transcription factor 2 6.16 7.21 0.23 0.01 0.01 12.34 Detail
371 LUAD cuproptosis AHR aryl hydrocarbon receptor 12.23 11.85 -0.05 0.01 0.01 12.27 Detail
372 LUAD cuproptosis MT2A metallothionein 2A 11.43 10.79 -0.08 0.01 0.01 12.16 Detail
373 LUAD cuproptosis ATP7B ATPase copper transporting beta 7.53 7.16 -0.07 0.01 0.01 12.0 Detail
374 LUAD cuproptosis ACO2 aconitase 2 11.25 11.13 -0.01 0.01 0.01 11.84 Detail
375 LUAD cuproptosis RPS27A ribosomal protein S27a 12.64 12.86 0.02 0.01 0.01 11.73 Detail
376 LUAD cuproptosis API5 apoptosis inhibitor 5 10.98 11.12 0.02 0.01 0.01 11.33 Detail
377 LUAD cuproptosis MADD MAP kinase activating death domain 10.23 10.06 -0.02 0.01 0.01 11.19 Detail
378 LUAD cuproptosis UQCRC2 ubiquinol-cytochrome c reductase core protein 2 11.28 11.44 0.02 0.01 0.01 11.08 Detail
379 LUAD cuproptosis NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 10.25 10.46 0.03 0.01 0.01 11.04 Detail
380 LUAD cuproptosis UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 10.29 10.53 0.03 0.01 0.01 11.03 Detail
381 LUAD cuproptosis CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 9.28 9.46 0.03 0.01 0.01 10.73 Detail
382 LUAD cuproptosis CDC27 cell division cycle 27 10.17 10.31 0.02 0.01 0.02 10.31 Detail
383 LUAD cuproptosis SP1 Sp1 transcription factor 11.27 11.15 -0.02 0.01 0.02 10.0 Detail
384 LUAD cuproptosis GLS glutaminase 11.66 11.38 -0.04 0.01 0.02 9.98 Detail
385 LUAD cuproptosis COX11 cytochrome c oxidase copper chaperone COX11 9.65 9.84 0.03 0.01 0.02 9.81 Detail
386 LUAD cuproptosis COMMD1 copper metabolism domain containing 1 7.89 8.09 0.04 0.01 0.02 9.73 Detail
387 LUAD cuproptosis XRN1 5'-3' exoribonuclease 1 9.93 9.76 -0.03 0.02 0.02 9.07 Detail
388 LUAD cuproptosis BRPF1 bromodomain and PHD finger containing 1 9.07 8.94 -0.02 0.02 0.02 8.91 Detail
389 LUAD cuproptosis ZKSCAN5 zinc finger with KRAB and SCAN domains 5 8.21 8.35 0.02 0.02 0.02 8.75 Detail
390 LUAD cuproptosis OSBPL9 oxysterol binding protein like 9 11.09 11.0 -0.01 0.02 0.02 8.69 Detail
391 LUAD cuproptosis UBE2D2 ubiquitin conjugating enzyme E2 D2 10.6 10.71 0.02 0.02 0.03 8.41 Detail
392 LUAD cuproptosis COQ2 coenzyme Q2, polyprenyltransferase 7.91 8.07 0.03 0.02 0.03 8.32 Detail
393 LUAD cuproptosis NDUFA6 NADH:ubiquinone oxidoreductase subunit A6 9.77 9.96 0.03 0.02 0.03 8.23 Detail
394 LUAD cuproptosis SLC25A26 solute carrier family 25 member 26 8.51 8.36 -0.02 0.02 0.03 8.07 Detail
395 LUAD cuproptosis EGLN1 egl-9 family hypoxia inducible factor 1 10.08 10.29 0.03 0.02 0.03 7.66 Detail
396 LUAD cuproptosis CMPK1 cytidine/uridine monophosphate kinase 1 11.88 12.01 0.02 0.02 0.03 7.63 Detail
397 LUAD cuproptosis CCL5 C-C motif chemokine ligand 5 10.13 9.69 -0.06 0.03 0.03 7.16 Detail
398 LUAD cuproptosis DDX20 DEAD-box helicase 20 8.58 8.46 -0.02 0.03 0.04 6.4 Detail
399 LUAD cuproptosis SERPIND1 serpin family D member 1 6.47 5.5 -0.24 0.03 0.04 6.32 Detail
400 LUAD cuproptosis SCAP SREBF chaperone 10.69 10.56 -0.02 0.04 0.04 5.79 Detail
401 LUAD cuproptosis HSPH1 heat shock protein family H (Hsp110) member 1 10.81 10.99 0.02 0.04 0.05 5.33 Detail
402 LUAD cuproptosis FDXR ferredoxin reductase 8.02 8.24 0.04 0.04 0.05 5.25 Detail
403 LUAD cuproptosis ATP7A ATPase copper transporting alpha 9.1 9.0 -0.02 0.27 0.3 0.0 Detail
404 LUAD cuproptosis CCDC22 coiled-coil domain containing 22 8.96 9.02 0.01 0.09 0.1 0.0 Detail
405 LUAD cuproptosis PRND prion like protein doppel 3.9 3.4 -0.2 0.16 0.19 0.0 Detail
406 LUAD cuproptosis AOC1 amine oxidase copper containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
407 LUAD cuproptosis AQP2 aquaporin 2 1.71 1.57 -0.13 0.16 0.19 0.0 Detail
408 LUAD cuproptosis MT1B metallothionein 1B 0.04 0.05 0.3 0.9 0.9 0.0 Detail
409 LUAD cuproptosis MT1DP metallothionein 1D, pseudogene 1.1 1.41 0.36 0.24 0.27 0.0 Detail
410 LUAD cuproptosis MT1G metallothionein 1G 5.19 5.52 0.09 0.18 0.21 0.0 Detail
411 LUAD cuproptosis MT1HL1 metallothionein 1H like 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
412 LUAD cuproptosis MT1X metallothionein 1X 9.02 8.6 -0.07 0.18 0.21 0.0 Detail
413 LUAD cuproptosis MT3 metallothionein 3 1.87 2.03 0.11 0.74 0.76 0.0 Detail
414 LUAD cuproptosis MT4 metallothionein 4 0.0 0.0 inf 0.64 0.67 0.0 Detail
415 LUAD cuproptosis CUTC cutC copper transporter 8.08 8.06 -0.0 0.54 0.58 0.0 Detail
416 LUAD cuproptosis SLC11A2 solute carrier family 11 member 2 10.66 10.71 0.01 0.6 0.63 0.0 Detail
417 LUAD cuproptosis FASLG Fas ligand 4.55 4.55 0.0 0.74 0.76 0.0 Detail
418 LUAD cuproptosis MLKL mixed lineage kinase domain like pseudokinase 8.56 8.38 -0.03 0.16 0.19 0.0 Detail
419 LUAD cuproptosis RIPK3 receptor interacting serine/threonine kinase 3 8.21 8.02 -0.03 0.37 0.4 0.0 Detail
420 LUAD cuproptosis LIPT1 lipoyltransferase 1 6.8 6.79 -0.0 0.8 0.81 0.0 Detail
421 LUAD cuproptosis DLD dihydrolipoamide dehydrogenase 10.42 10.48 0.01 0.57 0.6 0.0 Detail
422 LUAD cuproptosis PDHB pyruvate dehydrogenase E1 subunit beta 10.06 10.15 0.01 0.12 0.15 0.0 Detail
423 LUAD cuproptosis ABCB10 ATP binding cassette subfamily B member 10 8.94 9.03 0.01 0.12 0.14 0.0 Detail
424 LUAD cuproptosis ABCB11 ATP binding cassette subfamily B member 11 0.67 1.1 0.72 0.04 0.05 0.0 Detail
425 LUAD cuproptosis ACD ACD shelterin complex subunit and telomerase recruitment factor 8.2 8.3 0.02 0.11 0.13 0.0 Detail
426 LUAD cuproptosis ACO1 aconitase 1 10.55 10.5 -0.01 0.51 0.55 0.0 Detail
427 LUAD cuproptosis ACTR10 actin related protein 10 10.04 10.04 0.0 0.94 0.95 0.0 Detail
428 LUAD cuproptosis ADGRE5 adhesion G protein-coupled receptor E5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
429 LUAD cuproptosis AFG3L2 AFG3 like matrix AAA peptidase subunit 2 10.05 10.18 0.02 0.08 0.1 0.0 Detail
430 LUAD cuproptosis ALB albumin 1.4 2.53 0.85 0.07 0.08 0.0 Detail
431 LUAD cuproptosis ARFGEF1-DT ARFGEF1 divergent transcript 0.0 0.0 0.0 0.0 0.0 0.0 Detail
432 LUAD cuproptosis ARHGEF39 Rho guanine nucleotide exchange factor 39 0.0 0.0 0.0 0.0 0.0 0.0 Detail
433 LUAD cuproptosis ARMH3 armadillo like helical domain containing 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
434 LUAD cuproptosis ATF4 activating transcription factor 4 12.41 12.38 -0.0 0.65 0.67 0.0 Detail
435 LUAD cuproptosis ATM ATM serine/threonine kinase 9.88 9.86 -0.0 0.99 0.99 0.0 Detail
436 LUAD cuproptosis ATP5PD ATP synthase peripheral stalk subunit d 0.0 0.0 0.0 0.0 0.0 0.0 Detail
437 LUAD cuproptosis ATP6AP1 ATPase H+ transporting accessory protein 1 12.17 12.09 -0.01 0.15 0.18 0.0 Detail
438 LUAD cuproptosis ATP7BP1 ATPase copper transporting beta pseudogene 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
439 LUAD cuproptosis BCKDH protein phosphatase, Mg2+/Mn2+ dependent 1K 0.0 0.0 0.0 0.0 0.0 0.0 Detail
440 LUAD cuproptosis C6ORF136 chromosome 6 open reading frame 136 0.0 0.0 0.0 0.0 0.0 0.0 Detail
441 LUAD cuproptosis C7orf26 integrator complex subunit 15 9.15 9.18 0.0 0.76 0.78 0.0 Detail
442 LUAD cuproptosis CCL8 C-C motif chemokine ligand 8 5.46 5.73 0.07 0.38 0.42 0.0 Detail
443 LUAD cuproptosis CDC16 cell division cycle 16 10.11 10.11 0.0 0.69 0.71 0.0 Detail
444 LUAD cuproptosis CERS2 ceramide synthase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
445 LUAD cuproptosis CERT1 ceramide transporter 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
446 LUAD cuproptosis CHTOP chromatin target of PRMT1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
447 LUAD cuproptosis CIAO2A cytosolic iron-sulfur assembly component 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
448 LUAD cuproptosis CIAO2B cytosolic iron-sulfur assembly component 2B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
449 LUAD cuproptosis CLUH clustered mitochondria homolog 0.0 0.0 0.0 0.0 0.0 0.0 Detail
450 LUAD cuproptosis COA5 cytochrome c oxidase assembly factor 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
451 LUAD cuproptosis COA6 cytochrome c oxidase assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
452 LUAD cuproptosis COAS unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
453 LUAD cuproptosis copper鈥搝inc alloy (CZA) unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
454 LUAD cuproptosis COX14 cytochrome c oxidase assembly factor COX14 0.0 0.0 0.0 0.0 0.0 0.0 Detail
455 LUAD cuproptosis COX23 coiled-coil-helix-coiled-coil-helix domain containing 7 0.0 0.0 0.0 0.0 0.0 0.0 Detail
456 LUAD cuproptosis COX4I1 cytochrome c oxidase subunit 4I1 12.04 12.2 0.02 0.05 0.07 0.0 Detail
457 LUAD cuproptosis CTR1 solute carrier family 31 member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
458 LUAD cuproptosis CTR2 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
459 LUAD cuproptosis DARS1 aspartyl-tRNA synthetase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
460 LUAD cuproptosis DCYTB cytochrome b reductase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
461 LUAD cuproptosis DIP2B disco interacting protein 2 homolog B 10.04 10.08 0.01 0.54 0.58 0.0 Detail
462 LUAD cuproptosis DLST dihydrolipoamide S-succinyltransferase 11.06 11.05 -0.0 0.61 0.64 0.0 Detail
463 LUAD cuproptosis DMT1 solute carrier family 11 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
464 LUAD cuproptosis DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 10.27 10.41 0.02 0.06 0.07 0.0 Detail
465 LUAD cuproptosis DPH1 diphthamide biosynthesis 1 8.91 8.96 0.01 0.29 0.32 0.0 Detail
466 LUAD cuproptosis DYNLRB1 dynein light chain roadblock-type 1 11.02 11.0 -0.0 0.54 0.58 0.0 Detail
467 LUAD cuproptosis EFCC1 EF-hand and coiled-coil domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
468 LUAD cuproptosis EGFR epidermal growth factor receptor 10.13 9.86 -0.04 0.16 0.19 0.0 Detail
469 LUAD cuproptosis ELOB elongin B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
470 LUAD cuproptosis ELP3 elongator acetyltransferase complex subunit 3 9.39 9.38 -0.0 0.36 0.39 0.0 Detail
471 LUAD cuproptosis EMC6 ER membrane protein complex subunit 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
472 LUAD cuproptosis ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 7.82 7.74 -0.02 0.43 0.46 0.0 Detail
473 LUAD cuproptosis EPC2 enhancer of polycomb homolog 2 9.21 9.16 -0.01 0.78 0.79 0.0 Detail
474 LUAD cuproptosis ERK1 mitogen-activated protein kinase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
475 LUAD cuproptosis ETFDH electron transfer flavoprotein dehydrogenase 8.36 8.25 -0.02 0.16 0.19 0.0 Detail
476 LUAD cuproptosis EXOC3 exocyst complex component 3 10.16 10.35 0.03 0.04 0.05 0.0 Detail
477 LUAD cuproptosis FAK protein tyrosine kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
478 LUAD cuproptosis FAM111A FAM111 trypsin like peptidase A 9.85 9.82 -0.0 0.8 0.81 0.0 Detail
479 LUAD cuproptosis FASTKD5 FAST kinase domains 5 8.85 8.78 -0.01 0.6 0.63 0.0 Detail
480 LUAD cuproptosis FAU FAU ubiquitin like and ribosomal protein S30 fusion 12.56 12.69 0.02 0.06 0.07 0.0 Detail
481 LUAD cuproptosis FDX2 ferredoxin 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
482 LUAD cuproptosis FOXD2-AS1 FOXD2 adjacent opposite strand RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
483 LUAD cuproptosis FXN frataxin 7.34 7.38 0.01 0.55 0.59 0.0 Detail
484 LUAD cuproptosis GATB glutamyl-tRNA amidotransferase subunit B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
485 LUAD cuproptosis GLS40 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
486 LUAD cuproptosis glycerophospholipid unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
487 LUAD cuproptosis GRX1 glutaredoxin 0.0 0.0 0.0 0.0 0.0 0.0 Detail
488 LUAD cuproptosis GSH unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
489 LUAD cuproptosis GTF2B general transcription factor IIB 9.28 9.18 -0.02 0.05 0.06 0.0 Detail
490 LUAD cuproptosis GTPBP6 GTP binding protein 6 (putative) 0.0 0.0 0.0 0.0 0.0 0.0 Detail
491 LUAD cuproptosis H1-10-AS1 H1-10 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
492 LUAD cuproptosis H2AC6 H2A clustered histone 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
493 LUAD cuproptosis H2BC6-AS1 H2BC6 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
494 LUAD cuproptosis H3C1 H3 clustered histone 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
495 LUAD cuproptosis HSP70 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
496 LUAD cuproptosis IBA57 iron-sulfur cluster assembly factor IBA57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
497 LUAD cuproptosis IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta 10.05 10.12 0.01 0.24 0.27 0.0 Detail
498 LUAD cuproptosis IL-8 C-X-C motif chemokine ligand 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
499 LUAD cuproptosis INKA1 inka box actin regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
500 LUAD cuproptosis INTS6 integrator complex subunit 6 9.24 9.25 0.0 0.87 0.88 0.0 Detail
501 LUAD cuproptosis IOP1 cytosolic iron-sulfur assembly component 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
502 LUAD cuproptosis ISCU2 iron-sulfur cluster assembly enzyme 0.0 0.0 0.0 0.0 0.0 0.0 Detail
503 LUAD cuproptosis ISD11 LYR motif containing 4 0.0 0.0 0.0 0.0 0.0 0.0 Detail
504 LUAD cuproptosis KAT8 lysine acetyltransferase 8 0.0 0.0 0.0 0.0 0.0 0.0 Detail
505 LUAD cuproptosis KLF5 KLF transcription factor 5 11.2 11.0 -0.03 0.07 0.09 0.0 Detail
506 LUAD cuproptosis KMT2A lysine methyltransferase 2A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
507 LUAD cuproptosis LASTR lncRNA associated with SART3 regulation of splicing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
508 LUAD cuproptosis LINC02038 long intergenic non-protein coding RNA 2038 0.0 0.0 0.0 0.0 0.0 0.0 Detail
509 LUAD cuproptosis LINC02154 long intergenic non-protein coding RNA 2154 0.0 0.0 0.0 0.0 0.0 0.0 Detail
510 LUAD cuproptosis LINC03085 long intergenic non-protein coding RNA 3085 0.0 0.0 0.0 0.0 0.0 0.0 Detail
511 LUAD cuproptosis LIPT2 lipoyl(octanoyl) transferase 2 4.39 4.68 0.09 0.05 0.06 0.0 Detail
512 LUAD cuproptosis LOX lysyl oxidase 8.86 9.11 0.04 0.16 0.19 0.0 Detail
513 LUAD cuproptosis MAP2K1 mitogen-activated protein kinase kinase 1 10.48 10.5 0.0 0.83 0.84 0.0 Detail
514 LUAD cuproptosis MARCHF5 membrane associated ring-CH-type finger 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
515 LUAD cuproptosis MAU2 MAU2 sister chromatid cohesion factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
516 LUAD cuproptosis MBTPS1 membrane bound transcription factor peptidase, site 1 11.61 11.57 -0.01 0.47 0.5 0.0 Detail
517 LUAD cuproptosis MCMBP minichromosome maintenance complex binding protein 0.0 0.0 0.0 0.0 0.0 0.0 Detail
518 LUAD cuproptosis MCUR1 mitochondrial calcium uniporter regulator 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
519 LUAD cuproptosis MEK1 mitogen-activated protein kinase kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
520 LUAD cuproptosis MEK2 mitogen-activated protein kinase kinase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
521 LUAD cuproptosis METTL17 methyltransferase like 17 0.0 0.0 0.0 0.0 0.0 0.0 Detail
522 LUAD cuproptosis MOXD1 monooxygenase DBH like 1 9.3 9.44 0.02 0.18 0.21 0.0 Detail
523 LUAD cuproptosis MPC1 mitochondrial pyruvate carrier 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
524 LUAD cuproptosis MPZL3 myelin protein zero like 3 6.24 6.23 -0.0 0.42 0.45 0.0 Detail
525 LUAD cuproptosis MRM2 mitochondrial rRNA methyltransferase 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
526 LUAD cuproptosis MRPL14 mitochondrial ribosomal protein L14 10.53 10.46 -0.01 0.38 0.42 0.0 Detail
527 LUAD cuproptosis MRPL34 mitochondrial ribosomal protein L34 9.2 9.1 -0.02 0.19 0.22 0.0 Detail
528 LUAD cuproptosis MRPL39 mitochondrial ribosomal protein L39 8.1 8.27 0.03 0.06 0.07 0.0 Detail
529 LUAD cuproptosis MRPL57 mitochondrial ribosomal protein L57 0.0 0.0 0.0 0.0 0.0 0.0 Detail
530 LUAD cuproptosis MRPS18C mitochondrial ribosomal protein S18C 8.11 8.09 -0.0 0.61 0.64 0.0 Detail
531 LUAD cuproptosis MRPS22 mitochondrial ribosomal protein S22 8.66 8.75 0.01 0.34 0.37 0.0 Detail
532 LUAD cuproptosis MT1 metallothionein 1A 0.0 0.0 0.0 0.0 0.0 0.0 Detail
533 LUAD cuproptosis MT2 metallothionein 1B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
534 LUAD cuproptosis MT3A unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
535 LUAD cuproptosis MT-CO1 mitochondrially encoded cytochrome c oxidase I 0.0 0.0 0.0 0.0 0.0 0.0 Detail
536 LUAD cuproptosis MT-CO2 mitochondrially encoded cytochrome c oxidase II 0.0 0.0 0.0 0.0 0.0 0.0 Detail
537 LUAD cuproptosis MTCO2P12 MT-CO2 pseudogene 12 0.0 0.0 0.0 0.0 0.0 0.0 Detail
538 LUAD cuproptosis MT-CO3 mitochondrially encoded cytochrome c oxidase III 0.0 0.0 0.0 0.0 0.0 0.0 Detail
539 LUAD cuproptosis MT unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
540 LUAD cuproptosis MTERF1 mitochondrial transcription termination factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
541 LUAD cuproptosis MTFR1L mitochondrial fission regulator 1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
542 LUAD cuproptosis MTIF3 mitochondrial translational initiation factor 3 9.06 9.06 0.0 0.69 0.72 0.0 Detail
543 LUAD cuproptosis MTO1 mitochondrial tRNA translation optimization 1 8.33 8.37 0.01 0.33 0.37 0.0 Detail
544 LUAD cuproptosis mTOR mechanistic target of rapamycin kinase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
545 LUAD cuproptosis N6AMT1 N-6 adenine-specific DNA methyltransferase 1 7.73 7.62 -0.02 0.19 0.21 0.0 Detail
546 LUAD cuproptosis NARS2 asparaginyl-tRNA synthetase 2, mitochondrial 8.6 8.72 0.02 0.17 0.19 0.0 Detail
547 LUAD cuproptosis NDUFA4 NDUFA4 mitochondrial complex associated 11.46 11.6 0.02 0.11 0.13 0.0 Detail
548 LUAD cuproptosis NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 0.0 0.0 0.0 0.0 0.0 0.0 Detail
549 LUAD cuproptosis NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 9.17 9.23 0.01 0.41 0.45 0.0 Detail
550 LUAD cuproptosis NDUFB7 NADH:ubiquinone oxidoreductase subunit B7 9.92 10.03 0.01 0.18 0.2 0.0 Detail
551 LUAD cuproptosis NFU1 NFU1 iron-sulfur cluster scaffold 8.98 9.06 0.01 0.24 0.27 0.0 Detail
552 LUAD cuproptosis NFYC nuclear transcription factor Y subunit gamma 9.87 10.01 0.02 0.06 0.07 0.0 Detail
553 LUAD cuproptosis NPL4 NPL4 homolog, ubiquitin recognition factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
554 LUAD cuproptosis NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic 8.93 9.0 0.01 0.25 0.28 0.0 Detail
555 LUAD cuproptosis P3H3 prolyl 3-hydroxylase 3 0.0 0.0 0.0 0.0 0.0 0.0 Detail
556 LUAD cuproptosis p53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
557 LUAD cuproptosis P53 tumor protein p53 0.0 0.0 0.0 0.0 0.0 0.0 Detail
558 LUAD cuproptosis p97 eukaryotic translation initiation factor 4 gamma 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
559 LUAD cuproptosis PCBP2 poly(rC) binding protein 2 13.18 13.18 0.0 0.71 0.73 0.0 Detail
560 LUAD cuproptosis PDE12 phosphodiesterase 12 9.12 9.04 -0.01 0.27 0.3 0.0 Detail
561 LUAD cuproptosis PDHA pyruvate dehydrogenase E1 subunit alpha 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
562 LUAD cuproptosis PDH pyruvate dehydrogenase phosphatase catalytic subunit 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
563 LUAD cuproptosis PET100 PET100 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
564 LUAD cuproptosis PET117 PET117 cytochrome c oxidase chaperone 0.0 0.0 0.0 0.0 0.0 0.0 Detail
565 LUAD cuproptosis PHF5A PHD finger protein 5A 8.84 8.98 0.02 0.08 0.09 0.0 Detail
566 LUAD cuproptosis PHOB unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
567 LUAD cuproptosis PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.0 0.0 0.0 0.0 0.0 0.0 Detail
568 LUAD cuproptosis PMVK phosphomevalonate kinase 9.84 9.97 0.02 0.07 0.08 0.0 Detail
569 LUAD cuproptosis POLG DNA polymerase gamma, catalytic subunit 9.96 9.98 0.0 0.63 0.66 0.0 Detail
570 LUAD cuproptosis PSMD6 proteasome 26S subunit, non-ATPase 6 9.87 9.91 0.01 0.62 0.65 0.0 Detail
571 LUAD cuproptosis PTPMT1 protein tyrosine phosphatase mitochondrial 1 9.92 9.9 -0.0 0.88 0.89 0.0 Detail
572 LUAD cuproptosis QRSL1 glutaminyl-tRNA amidotransferase subunit QRSL1 8.32 8.46 0.02 0.04 0.05 0.0 Detail
573 LUAD cuproptosis RANTES C-C motif chemokine ligand 5 0.0 0.0 0.0 0.0 0.0 0.0 Detail
574 LUAD cuproptosis RCC1L RCC1 like 0.0 0.0 0.0 0.0 0.0 0.0 Detail
575 LUAD cuproptosis RPAIN RPA interacting protein 9.0 9.18 0.03 0.08 0.09 0.0 Detail
576 LUAD cuproptosis RPAP1 RNA polymerase II associated protein 1 8.91 9.01 0.02 0.1 0.12 0.0 Detail
577 LUAD cuproptosis RPL3 ribosomal protein L3 14.73 14.81 0.01 0.34 0.37 0.0 Detail
578 LUAD cuproptosis S6K1 ribosomal protein S6 kinase B1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
579 LUAD cuproptosis SAMM50 SAMM50 sorting and assembly machinery component 9.54 9.58 0.01 0.57 0.6 0.0 Detail
580 LUAD cuproptosis SDHD succinate dehydrogenase complex subunit D 10.78 10.69 -0.01 0.17 0.2 0.0 Detail
581 LUAD cuproptosis SEPTIN1 septin 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
582 LUAD cuproptosis SERPINE1 serpin family E member 1 10.57 10.56 -0.0 0.92 0.92 0.0 Detail
583 LUAD cuproptosis SGF29 SAGA complex associated factor 29 0.0 0.0 0.0 0.0 0.0 0.0 Detail
584 LUAD cuproptosis SLC16A1 solute carrier family 16 member 1 7.92 8.29 0.06 0.26 0.29 0.0 Detail
585 LUAD cuproptosis SLC25A19 solute carrier family 25 member 19 8.17 8.27 0.02 0.15 0.17 0.0 Detail
586 LUAD cuproptosis SLC25A32 solute carrier family 25 member 32 9.06 9.15 0.01 0.26 0.29 0.0 Detail
587 LUAD cuproptosis SLC25A3 solute carrier family 25 member 3 12.57 12.58 0.0 0.8 0.81 0.0 Detail
588 LUAD cuproptosis SLC25A51 solute carrier family 25 member 51 0.0 0.0 0.0 0.0 0.0 0.0 Detail
589 LUAD cuproptosis SLC52A2 solute carrier family 52 member 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
590 LUAD cuproptosis SMAD3-AS1 SMAD3 antisense RNA 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
591 LUAD cuproptosis SOD2 superoxide dismutase 2 12.79 12.56 -0.03 0.07 0.09 0.0 Detail
592 LUAD cuproptosis sp1 Sp1 transcription factor 0.0 0.0 0.0 0.0 0.0 0.0 Detail
593 LUAD cuproptosis SPARC secreted protein acidic and cysteine rich 14.57 14.43 -0.01 0.34 0.38 0.0 Detail
594 LUAD cuproptosis SPATA5 AFG2 AAA ATPase homolog A 7.5 7.41 -0.02 0.14 0.17 0.0 Detail
595 LUAD cuproptosis SPDYE1 speedy/RINGO cell cycle regulator family member E1 3.58 3.68 0.04 0.54 0.58 0.0 Detail
596 LUAD cuproptosis STEAP4 unknown 0.0 0.0 0.0 0.0 0.0 0.0 Detail
597 LUAD cuproptosis STEAP STEAP family member 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
598 LUAD cuproptosis STK11 serine/threonine kinase 11 9.74 9.49 -0.04 0.21 0.23 0.0 Detail
599 LUAD cuproptosis SURF1 SURF1 cytochrome c oxidase assembly factor 9.59 9.7 0.02 0.24 0.27 0.0 Detail
600 LUAD cuproptosis TANK TRAF family member associated NFKB activator 9.95 9.85 -0.01 0.05 0.07 0.0 Detail
601 LUAD cuproptosis TEDC1 tubulin epsilon and delta complex 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
602 LUAD cuproptosis TEFM transcription elongation factor, mitochondrial 0.0 0.0 0.0 0.0 0.0 0.0 Detail
603 LUAD cuproptosis TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
604 LUAD cuproptosis TMEM191B transmembrane protein 191B 0.0 0.0 0.0 0.0 0.0 0.0 Detail
605 LUAD cuproptosis TRAPPC11 trafficking protein particle complex subunit 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
606 LUAD cuproptosis TUBGCP4 tubulin gamma complex component 4 7.56 7.73 0.03 0.06 0.07 0.0 Detail
607 LUAD cuproptosis TWNK twinkle mtDNA helicase 0.0 0.0 0.0 0.0 0.0 0.0 Detail
608 LUAD cuproptosis TYR tyrosinase 0.0 0.13 inf 0.01 0.01 0.0 Detail
609 LUAD cuproptosis U2SURP U2 snRNP associated SURP domain containing 0.0 0.0 0.0 0.0 0.0 0.0 Detail
610 LUAD cuproptosis UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 8.03 8.09 0.01 0.53 0.57 0.0 Detail
611 LUAD cuproptosis UlK1 unc-51 like autophagy activating kinase 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
612 LUAD cuproptosis UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
613 LUAD cuproptosis UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 0.0 0.0 0.0 0.0 0.0 0.0 Detail
614 LUAD cuproptosis USE1 unconventional SNARE in the ER 1 8.0 8.11 0.02 0.2 0.23 0.0 Detail
615 LUAD cuproptosis UTP25 UTP25 small subunit processome component 0.0 0.0 0.0 0.0 0.0 0.0 Detail
616 LUAD cuproptosis VEGFA vascular endothelial growth factor A 12.04 12.08 0.0 0.76 0.78 0.0 Detail
617 LUAD cuproptosis xCT solute carrier family 7 member 11 0.0 0.0 0.0 0.0 0.0 0.0 Detail
618 LUAD cuproptosis YAE1 YAE1 maturation factor of ABCE1 0.0 0.0 0.0 0.0 0.0 0.0 Detail
619 LUAD cuproptosis YEATS2 YEATS domain containing 2 9.8 9.92 0.02 0.49 0.53 0.0 Detail
620 LUAD cuproptosis ZBTB11 zinc finger and BTB domain containing 11 9.26 9.33 0.01 0.06 0.07 0.0 Detail

Ensemble learning for LUAD based on specific cuproptosis gene regulaors.