Disease specific cell death gene regulator search
Search Results:
LUSC specific anoikis gene regulaors.
Different color in column1 means high , low , non-diff expressed gene in disease.
| NO. | Disease | CellDeathType | Genesymbol | Fullname | Control_mean | Disease_mean | log2FC | pvalue | padj | Weight | Detail |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | LUSC | anoikis | CHEK2 | checkpoint kinase 2 | 6.66 | 8.96 | 0.43 | 0.0 | 0.0 | 100.0 | Detail |
| 2 | LUSC | anoikis | PDK4 | pyruvate dehydrogenase kinase 4 | 11.93 | 7.1 | -0.75 | 0.0 | 0.0 | 99.93 | Detail |
| 3 | LUSC | anoikis | CAV1 | caveolin 1 | 14.7 | 11.0 | -0.42 | 0.0 | 0.0 | 99.62 | Detail |
| 4 | LUSC | anoikis | DAPK2 | death associated protein kinase 2 | 10.05 | 7.18 | -0.48 | 0.0 | 0.0 | 95.39 | Detail |
| 5 | LUSC | anoikis | E2F1 | E2F transcription factor 1 | 7.08 | 8.95 | 0.34 | 0.0 | 0.0 | 92.65 | Detail |
| 6 | LUSC | anoikis | TFDP1 | transcription factor Dp-1 | 10.18 | 11.28 | 0.15 | 0.0 | 0.0 | 89.83 | Detail |
| 7 | LUSC | anoikis | MYBBP1A | MYB binding protein 1a | 9.38 | 10.51 | 0.16 | 0.0 | 0.0 | 80.3 | Detail |
| 8 | LUSC | anoikis | PTRH2 | peptidyl-tRNA hydrolase 2 | 7.9 | 8.85 | 0.16 | 0.0 | 0.0 | 76.81 | Detail |
| 9 | LUSC | anoikis | BRMS1 | BRMS1 transcriptional repressor and anoikis regulator | 9.42 | 10.18 | 0.11 | 0.0 | 0.0 | 76.18 | Detail |
| 10 | LUSC | anoikis | SNAI2 | snail family transcriptional repressor 2 | 7.97 | 9.82 | 0.3 | 0.0 | 0.0 | 75.72 | Detail |
| 11 | LUSC | anoikis | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 9.2 | 9.78 | 0.09 | 0.0 | 0.0 | 73.44 | Detail |
| 12 | LUSC | anoikis | MCL1 | MCL1 apoptosis regulator, BCL2 family member | 13.98 | 13.03 | -0.1 | 0.0 | 0.0 | 71.63 | Detail |
| 13 | LUSC | anoikis | SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 10.24 | 11.01 | 0.1 | 0.0 | 0.0 | 66.24 | Detail |
| 14 | LUSC | anoikis | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 8.92 | 9.69 | 0.12 | 0.0 | 0.0 | 50.79 | Detail |
| 15 | LUSC | anoikis | SIK1 | salt inducible kinase 1 | 11.89 | 10.84 | -0.13 | 0.0 | 0.0 | 40.21 | Detail |
| 16 | LUSC | anoikis | BCL2L1 | BCL2 like 1 | 11.83 | 11.38 | -0.06 | 0.0 | 0.0 | 32.48 | Detail |
| 17 | LUSC | anoikis | ANKRD13C | ankyrin repeat domain 13C | 9.12 | 8.85 | -0.04 | 0.0 | 0.0 | 30.15 | Detail |
| 18 | LUSC | anoikis | NTRK2 | neurotrophic receptor tyrosine kinase 2 | 9.27 | 11.05 | 0.25 | 0.0 | 0.0 | 23.17 | Detail |
| 19 | LUSC | anoikis | STK11 | serine/threonine kinase 11 | 9.59 | 9.91 | 0.05 | 0.0 | 0.0 | 12.88 | Detail |
| 20 | LUSC | anoikis | ITGB1 | integrin subunit beta 1 | 13.68 | 13.33 | -0.04 | 0.0 | 0.0 | 12.51 | Detail |
| 21 | LUSC | anoikis | ITGA5 | integrin subunit alpha 5 | 11.99 | 11.41 | -0.07 | 0.0 | 0.0 | 10.83 | Detail |
| 22 | LUSC | anoikis | PTK2 | protein tyrosine kinase 2 | 11.1 | 11.35 | 0.03 | 0.0 | 0.0 | 10.0 | Detail |
| 23 | LUSC | anoikis | IKBKG | inhibitor of nuclear factor kappa B kinase regulatory subunit gamma | 9.04 | 9.28 | 0.04 | 0.0 | 0.0 | 2.17 | Detail |
| 24 | LUSC | anoikis | BCL2 | BCL2 apoptosis regulator | 8.58 | 8.43 | -0.03 | 0.15 | 0.16 | 0.0 | Detail |
| 25 | LUSC | anoikis | BMF | Bcl2 modifying factor | 8.99 | 8.77 | -0.04 | 0.2 | 0.21 | 0.0 | Detail |
| 26 | LUSC | anoikis | CRYBA1 | crystallin beta A1 | 0.15 | 0.13 | -0.13 | 0.57 | 0.57 | 0.0 | Detail |
| 27 | LUSC | anoikis | NOTCH1 | notch receptor 1 | 11.02 | 10.78 | -0.03 | 0.06 | 0.07 | 0.0 | Detail |
| 28 | LUSC | anoikis | TLE1 | TLE family member 1, transcriptional corepressor | 9.13 | 9.23 | 0.02 | 0.11 | 0.13 | 0.0 | Detail |
| 29 | LUSC | anoikis | TSC2 | TSC complex subunit 2 | 10.61 | 10.37 | -0.03 | 0.0 | 0.0 | 0.0 | Detail |
Ensemble learning visualization:
Ensemble learning for LUSC based on specific anoikis gene regulaors.
