Disease specific cell death gene regulator search
Search Results:
PAAD specific anoikis gene regulaors.
Different color in column1 means high , low , non-diff expressed gene in disease.
| NO. | Disease | CellDeathType | Genesymbol | Fullname | Control_mean | Disease_mean | log2FC | pvalue | padj | Weight | Detail |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PAAD | anoikis | NOTCH1 | notch receptor 1 | 10.91 | 10.21 | -0.1 | 0.02 | 0.28 | 100.0 | Detail |
| 2 | PAAD | anoikis | BMF | Bcl2 modifying factor | 10.68 | 9.23 | -0.21 | 0.02 | 0.28 | 97.86 | Detail |
| 3 | PAAD | anoikis | BCL2 | BCL2 apoptosis regulator | 9.63 | 7.93 | -0.28 | 0.05 | 0.28 | 83.57 | Detail |
| 4 | PAAD | anoikis | PTK2 | protein tyrosine kinase 2 | 10.62 | 11.07 | 0.06 | 0.06 | 0.28 | 77.86 | Detail |
| 5 | PAAD | anoikis | BCL2L1 | BCL2 like 1 | 11.45 | 12.26 | 0.1 | 0.06 | 0.28 | 77.14 | Detail |
| 6 | PAAD | anoikis | DAPK2 | death associated protein kinase 2 | 8.23 | 7.48 | -0.14 | 0.07 | 0.28 | 75.71 | Detail |
| 7 | PAAD | anoikis | CRYBA1 | crystallin beta A1 | 0.44 | 0.16 | -1.46 | 0.07 | 0.28 | 55.71 | Detail |
| 8 | PAAD | anoikis | TLE1 | TLE family member 1, transcriptional corepressor | 10.32 | 9.92 | -0.06 | 0.19 | 0.63 | 52.14 | Detail |
| 9 | PAAD | anoikis | IKBKG | inhibitor of nuclear factor kappa B kinase regulatory subunit gamma | 9.41 | 9.07 | -0.05 | 0.21 | 0.63 | 49.29 | Detail |
| 10 | PAAD | anoikis | MYBBP1A | MYB binding protein 1a | 10.06 | 9.7 | -0.05 | 0.23 | 0.63 | 47.86 | Detail |
| 11 | PAAD | anoikis | SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 10.86 | 11.36 | 0.06 | 0.24 | 0.63 | 46.43 | Detail |
| 12 | PAAD | anoikis | CAV1 | caveolin 1 | 11.46 | 10.88 | -0.07 | 0.27 | 0.63 | 42.86 | Detail |
| 13 | PAAD | anoikis | E2F1 | E2F transcription factor 1 | 6.89 | 7.37 | 0.1 | 0.31 | 0.63 | 39.29 | Detail |
| 14 | PAAD | anoikis | TFDP1 | transcription factor Dp-1 | 10.37 | 10.51 | 0.02 | 0.31 | 0.63 | 39.29 | Detail |
| 15 | PAAD | anoikis | NTRK2 | neurotrophic receptor tyrosine kinase 2 | 9.52 | 8.85 | -0.11 | 0.4 | 0.72 | 30.71 | Detail |
| 16 | PAAD | anoikis | SIK1 | salt inducible kinase 1 | 10.51 | 11.12 | 0.08 | 0.41 | 0.72 | 30.0 | Detail |
| 17 | PAAD | anoikis | CHEK2 | checkpoint kinase 2 | 7.23 | 6.97 | -0.05 | 0.42 | 0.72 | 29.29 | Detail |
| 18 | PAAD | anoikis | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 9.47 | 9.17 | -0.05 | 0.5 | 0.76 | 23.57 | Detail |
| 19 | PAAD | anoikis | PDK4 | pyruvate dehydrogenase kinase 4 | 11.12 | 10.78 | -0.05 | 0.5 | 0.76 | 23.57 | Detail |
| 20 | PAAD | anoikis | TSC2 | TSC complex subunit 2 | 10.81 | 10.71 | -0.01 | 0.56 | 0.81 | 19.29 | Detail |
| 21 | PAAD | anoikis | BRMS1 | BRMS1 transcriptional repressor and anoikis regulator | 10.08 | 9.99 | -0.01 | 0.59 | 0.82 | 17.14 | Detail |
| 22 | PAAD | anoikis | ITGB1 | integrin subunit beta 1 | 13.93 | 14.2 | 0.03 | 0.75 | 0.83 | 7.14 | Detail |
| 23 | PAAD | anoikis | SNAI2 | snail family transcriptional repressor 2 | 8.98 | 8.73 | -0.04 | 0.75 | 0.83 | 7.14 | Detail |
| 24 | PAAD | anoikis | STK11 | serine/threonine kinase 11 | 10.28 | 10.19 | -0.01 | 0.75 | 0.83 | 7.14 | Detail |
| 25 | PAAD | anoikis | ITGA5 | integrin subunit alpha 5 | 11.67 | 11.73 | 0.01 | 0.76 | 0.83 | 6.43 | Detail |
| 26 | PAAD | anoikis | PTRH2 | peptidyl-tRNA hydrolase 2 | 8.4 | 8.51 | 0.02 | 0.76 | 0.83 | 6.43 | Detail |
| 27 | PAAD | anoikis | ANKRD13C | ankyrin repeat domain 13C | 8.99 | 8.91 | -0.01 | 0.78 | 0.83 | 5.71 | Detail |
| 28 | PAAD | anoikis | MCL1 | MCL1 apoptosis regulator, BCL2 family member | 13.52 | 13.37 | -0.02 | 0.87 | 0.87 | 0.0 | Detail |
| 29 | PAAD | anoikis | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 8.79 | 8.67 | -0.02 | 0.87 | 0.87 | 0.0 | Detail |
Ensemble learning visualization:
Ensemble learning for PAAD based on specific anoikis gene regulaors.
