Disease associated with RCD disease & gene list




THCA specific anoikis gene regulaors.

Different color in column1 means high , low , non-diff expressed gene in disease.


NO. Disease CellDeathType Genesymbol Fullname Control_mean Disease_mean log2FC pvalue padj Weight Detail
1 THCA anoikis TLE1 TLE family member 1, transcriptional corepressor 9.76 8.42 -0.21 0.0 0.0 100.0 Detail
2 THCA anoikis BCL2 BCL2 apoptosis regulator 11.87 10.09 -0.23 0.0 0.0 98.76 Detail
3 THCA anoikis BCL2L1 BCL2 like 1 10.77 11.77 0.13 0.0 0.0 96.51 Detail
4 THCA anoikis E2F1 E2F transcription factor 1 5.42 7.46 0.46 0.0 0.0 87.9 Detail
5 THCA anoikis TFDP1 transcription factor Dp-1 10.6 10.2 -0.06 0.0 0.0 83.57 Detail
6 THCA anoikis SRC SRC proto-oncogene, non-receptor tyrosine kinase 9.38 9.95 0.09 0.0 0.0 80.89 Detail
7 THCA anoikis DAPK2 death associated protein kinase 2 10.67 12.07 0.18 0.0 0.0 72.8 Detail
8 THCA anoikis ITGB1 integrin subunit beta 1 12.46 12.86 0.05 0.0 0.0 55.61 Detail
9 THCA anoikis MYBBP1A MYB binding protein 1a 9.65 10.0 0.05 0.0 0.0 54.8 Detail
10 THCA anoikis ANKRD13C ankyrin repeat domain 13C 9.21 8.97 -0.04 0.0 0.0 52.06 Detail
11 THCA anoikis NTRK2 neurotrophic receptor tyrosine kinase 2 13.77 13.22 -0.06 0.0 0.0 39.99 Detail
12 THCA anoikis ITGA5 integrin subunit alpha 5 9.81 10.28 0.07 0.0 0.0 37.36 Detail
13 THCA anoikis MCL1 MCL1 apoptosis regulator, BCL2 family member 13.45 13.01 -0.05 0.0 0.0 26.39 Detail
14 THCA anoikis CHEK2 checkpoint kinase 2 6.87 7.15 0.06 0.0 0.0 25.62 Detail
15 THCA anoikis STK11 serine/threonine kinase 11 10.1 10.32 0.03 0.0 0.0 23.7 Detail
16 THCA anoikis BMF Bcl2 modifying factor 9.9 10.34 0.06 0.0 0.0 22.69 Detail
17 THCA anoikis PTK2 protein tyrosine kinase 2 10.92 11.07 0.02 0.0 0.0 22.48 Detail
18 THCA anoikis PTRH2 peptidyl-tRNA hydrolase 2 7.82 7.97 0.03 0.0 0.0 14.45 Detail
19 THCA anoikis CAV1 caveolin 1 12.87 12.29 -0.07 0.0 0.0 13.41 Detail
20 THCA anoikis BRMS1 BRMS1 transcriptional repressor and anoikis regulator 9.75 9.89 0.02 0.0 0.0 11.77 Detail
21 THCA anoikis IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma 8.76 8.62 -0.02 0.01 0.02 4.75 Detail
22 THCA anoikis MAP3K7 mitogen-activated protein kinase kinase kinase 7 9.44 9.3 -0.02 0.02 0.02 3.47 Detail
23 THCA anoikis CRYBA1 crystallin beta A1 0.07 0.06 -0.24 0.37 0.4 0.0 Detail
24 THCA anoikis NOTCH1 notch receptor 1 9.37 9.61 0.04 0.04 0.05 0.0 Detail
25 THCA anoikis PDK4 pyruvate dehydrogenase kinase 4 12.17 12.09 -0.01 0.57 0.59 0.0 Detail
26 THCA anoikis PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 8.54 8.37 -0.03 0.06 0.07 0.0 Detail
27 THCA anoikis SIK1 salt inducible kinase 1 9.75 9.74 -0.0 0.87 0.87 0.0 Detail
28 THCA anoikis SNAI2 snail family transcriptional repressor 2 6.76 6.44 -0.07 0.09 0.1 0.0 Detail
29 THCA anoikis TSC2 TSC complex subunit 2 11.12 11.06 -0.01 0.08 0.09 0.0 Detail

Ensemble learning for THCA based on specific anoikis gene regulaors.