Disease specific cell death gene regulator search
Search Results:
THCA specific anoikis gene regulaors.
Different color in column1 means high , low , non-diff expressed gene in disease.
NO. | Disease | CellDeathType | Genesymbol | Fullname | Control_mean | Disease_mean | log2FC | pvalue | padj | Weight | Detail |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | THCA | anoikis | TLE1 | TLE family member 1, transcriptional corepressor | 9.76 | 8.42 | -0.21 | 0.0 | 0.0 | 100.0 | Detail |
2 | THCA | anoikis | BCL2 | BCL2 apoptosis regulator | 11.87 | 10.09 | -0.23 | 0.0 | 0.0 | 98.76 | Detail |
3 | THCA | anoikis | BCL2L1 | BCL2 like 1 | 10.77 | 11.77 | 0.13 | 0.0 | 0.0 | 96.51 | Detail |
4 | THCA | anoikis | E2F1 | E2F transcription factor 1 | 5.42 | 7.46 | 0.46 | 0.0 | 0.0 | 87.9 | Detail |
5 | THCA | anoikis | TFDP1 | transcription factor Dp-1 | 10.6 | 10.2 | -0.06 | 0.0 | 0.0 | 83.57 | Detail |
6 | THCA | anoikis | SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 9.38 | 9.95 | 0.09 | 0.0 | 0.0 | 80.89 | Detail |
7 | THCA | anoikis | DAPK2 | death associated protein kinase 2 | 10.67 | 12.07 | 0.18 | 0.0 | 0.0 | 72.8 | Detail |
8 | THCA | anoikis | ITGB1 | integrin subunit beta 1 | 12.46 | 12.86 | 0.05 | 0.0 | 0.0 | 55.61 | Detail |
9 | THCA | anoikis | MYBBP1A | MYB binding protein 1a | 9.65 | 10.0 | 0.05 | 0.0 | 0.0 | 54.8 | Detail |
10 | THCA | anoikis | ANKRD13C | ankyrin repeat domain 13C | 9.21 | 8.97 | -0.04 | 0.0 | 0.0 | 52.06 | Detail |
11 | THCA | anoikis | NTRK2 | neurotrophic receptor tyrosine kinase 2 | 13.77 | 13.22 | -0.06 | 0.0 | 0.0 | 39.99 | Detail |
12 | THCA | anoikis | ITGA5 | integrin subunit alpha 5 | 9.81 | 10.28 | 0.07 | 0.0 | 0.0 | 37.36 | Detail |
13 | THCA | anoikis | MCL1 | MCL1 apoptosis regulator, BCL2 family member | 13.45 | 13.01 | -0.05 | 0.0 | 0.0 | 26.39 | Detail |
14 | THCA | anoikis | CHEK2 | checkpoint kinase 2 | 6.87 | 7.15 | 0.06 | 0.0 | 0.0 | 25.62 | Detail |
15 | THCA | anoikis | STK11 | serine/threonine kinase 11 | 10.1 | 10.32 | 0.03 | 0.0 | 0.0 | 23.7 | Detail |
16 | THCA | anoikis | BMF | Bcl2 modifying factor | 9.9 | 10.34 | 0.06 | 0.0 | 0.0 | 22.69 | Detail |
17 | THCA | anoikis | PTK2 | protein tyrosine kinase 2 | 10.92 | 11.07 | 0.02 | 0.0 | 0.0 | 22.48 | Detail |
18 | THCA | anoikis | PTRH2 | peptidyl-tRNA hydrolase 2 | 7.82 | 7.97 | 0.03 | 0.0 | 0.0 | 14.45 | Detail |
19 | THCA | anoikis | CAV1 | caveolin 1 | 12.87 | 12.29 | -0.07 | 0.0 | 0.0 | 13.41 | Detail |
20 | THCA | anoikis | BRMS1 | BRMS1 transcriptional repressor and anoikis regulator | 9.75 | 9.89 | 0.02 | 0.0 | 0.0 | 11.77 | Detail |
21 | THCA | anoikis | IKBKG | inhibitor of nuclear factor kappa B kinase regulatory subunit gamma | 8.76 | 8.62 | -0.02 | 0.01 | 0.02 | 4.75 | Detail |
22 | THCA | anoikis | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 9.44 | 9.3 | -0.02 | 0.02 | 0.02 | 3.47 | Detail |
23 | THCA | anoikis | CRYBA1 | crystallin beta A1 | 0.07 | 0.06 | -0.24 | 0.37 | 0.4 | 0.0 | Detail |
24 | THCA | anoikis | NOTCH1 | notch receptor 1 | 9.37 | 9.61 | 0.04 | 0.04 | 0.05 | 0.0 | Detail |
25 | THCA | anoikis | PDK4 | pyruvate dehydrogenase kinase 4 | 12.17 | 12.09 | -0.01 | 0.57 | 0.59 | 0.0 | Detail |
26 | THCA | anoikis | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 8.54 | 8.37 | -0.03 | 0.06 | 0.07 | 0.0 | Detail |
27 | THCA | anoikis | SIK1 | salt inducible kinase 1 | 9.75 | 9.74 | -0.0 | 0.87 | 0.87 | 0.0 | Detail |
28 | THCA | anoikis | SNAI2 | snail family transcriptional repressor 2 | 6.76 | 6.44 | -0.07 | 0.09 | 0.1 | 0.0 | Detail |
29 | THCA | anoikis | TSC2 | TSC complex subunit 2 | 11.12 | 11.06 | -0.01 | 0.08 | 0.09 | 0.0 | Detail |
Ensemble learning visualization:
Ensemble learning for THCA based on specific anoikis gene regulaors.

