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GENE：DYNLL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DYNLL2
FullNmae dynein light chain LC8-type 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24596
EnsembleID ENSG00000264364
Uniprot Q96FJ2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DYNLL2 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DYNLL2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DYNLL2 GO:0005515,GO:0005634,GO:0005813,GO:0005829,GO:0005856,GO:0005868,GO:0005874,GO:0005886,GO:0005929,GO:0007017,GO:0016020,GO:0031475,GO:0045505,GO:0097542,GO:0097731,GO:0098794,GO:0098794,GO:0098978,GO:0098978

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DYNLL2 hsa:140735 path:hsa04814 Motor proteins - Homo sapiens (human)
DYNLL2 hsa:140735 path:hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human)
DYNLL2 hsa:140735 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 DYNLL2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB DYNLL2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00003BBF48 DYNLL2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001B341F DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D860 DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD DYNLL2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C DYNLL2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000458AD2 DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 DYNLL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 DYNLL2 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF DYNLL2 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075A9CF DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004DEA91 DYNLL2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 DYNLL2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 DYNLL2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 DYNLL2 20371350 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 DYNLL2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 DYNLL2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 DYNLL2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 DYNLL2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 DYNLL2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000DD591 DYNLL2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 DYNLL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000315338 DYNLL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001CC864 DYNLL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000183BED DYNLL2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002DD349 DYNLL2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DYNLL1 DYNLL2 17353931 24234451 25348397 27173435 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
BCL2L11 DYNLL2 25348397 N/A physical interaction ComPPI
DYNLL2 DNAL4 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
DYNLL2 BMF 11546872 14525934 14561217 24234451 25348397 25416956 physical association experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
DYNLL2 DLGAP1 10844022 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
DYNLL2 GPHN 12097491 14525934 24234451 25348397 27173435 association,physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
DYNLL2 EWSR1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DYNLL2 XIAP 14525934 16189514 24234451 25348397 27173435 association,physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
DYNLL2 HOMER3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
DYNLL2 DYNC1I1 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DYNLL2 MYO5A 10844022 11546872 14525934 17029413 20889982 25348397 27898060 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
DYNLL2 DLG4 25348397 N/A physical interaction ComPPI
DYNLL2 DLG2 25348397 N/A physical interaction ComPPI
DYNLL2 SHANK2 25348397 N/A physical interaction ComPPI
DYNLL2 AMOT 19615732 24234451 24366813 25348397 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 PAK1 15845372 20889982 21988832 24234451 25348397 27898060 physical association two hybrid,physical interaction ComPPI,IntAct,OmniPath
DYNLL2 DYRK1A 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DYNLL2 CSNK1A1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DYNLL2 RASGRP3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DYNLL2 HMBOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DYNLL2 IHO1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DYNLL2 EED 25348397 N/A physical interaction ComPPI
DYNLL2 WWC1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DYNLL2 PCBP1 25348397 N/A physical interaction ComPPI
DYNLL2 H2BC11 25348397 N/A physical interaction ComPPI
DYNLL2 H2BC4 25348397 N/A physical interaction ComPPI
DYNLL2 SKAP1 25348397 N/A physical interaction ComPPI
DYNLL2 MCM2 25348397 N/A physical interaction ComPPI
DYNLL2 DYNC2I2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 NRF1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 SHMT2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 CIZ1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 NEK9 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 MTPAP 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 TLK2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 DIABLO 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 CLINT1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 AMBRA1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 SKP1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 DCAF7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 OFD1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 RAF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 PPP1CB 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 DYNLT1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DYNLL2 G3BP1 25348397 N/A physical interaction ComPPI
DYNLL2 STRN4 18782753 24234451 25348397 association tandem affinity purification ComPPI,IntAct
DYNLL2 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DYNLL2 SFMBT1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
DYNLL2 TLK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL2 GABARAPL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL2 SEPTIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL2 KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL2 SUDS3 24234451 30021884 physical association cross-linking study IntAct
DYNLL2 BMF 11546872 12209154 14561217 20889982 25416956 27898060 inhibition N/A OmniPath
DYNLL2 AMBRA1 20921139 27898060 inhibition N/A OmniPath

Visualization










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