Gene Information gene info

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GENE：FUNDC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FUNDC1
FullNmae FUN14 domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28746
EnsembleID ENSG00000069509
Uniprot Q8IVP5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FUNDC1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FUNDC1 GO:0000422,GO:0000422,GO:0000422,GO:0000422,GO:0001666,GO:0001666,GO:0005515,GO:0005741,GO:0005741,GO:0010243

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FUNDC1 hsa:139341 path:hsa04137 Mitophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 FUNDC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 FUNDC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FUNDC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 FUNDC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E3523 FUNDC1 24573672 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
YES1 FUNDC1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 FUNDC1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GABARAPL2 FUNDC1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAP1LC3B FUNDC1 20562859 24234451 24671035 25348397 25416956 27898060 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,fluorescence microscopy,bimolecular fluorescence complementation,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
FUNDC1 CTBP1 25348397 N/A physical interaction ComPPI
FUNDC1 CTBP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FUNDC1 EHHADH 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FUNDC1 SNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FUNDC1 GABARAPL1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
FUNDC1 SENP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FUNDC1 MAP1LC3A 20562859 24234451 25348397 25416956 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FUNDC1 MARCHF5 25348397 N/A physical interaction ComPPI
TUFM FUNDC1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SRC FUNDC1 22267086 27898060 inhibition N/A OmniPath

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