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GENE：LAMTOR1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LAMTOR1
FullNmae late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26068
EnsembleID ENSG00000149357
Uniprot Q6IAA8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LAMTOR1 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
LAMTOR1 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
LAMTOR1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LAMTOR1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
LAMTOR1 GO:0001558,GO:0001919,GO:0001919,GO:0005085,GO:0005085,GO:0005515,GO:0005764,GO:0005764,GO:0005765,GO:0005765,GO:0005765,GO:0005886,GO:0007032,GO:0007040,GO:0008104,GO:0010874,GO:0016197,GO:0031669,GO:0031902,GO:0031902,GO:0032008,GO:0032418,GO:0035577,GO:0035579,GO:0038202,GO:0042632,GO:0043410,GO:0043410,GO:0043495,GO:0045121,GO:0051020,GO:0060090,GO:0060090,GO:0060620,GO:0070062,GO:0071230,GO:0071230,GO:0071230,GO:0071986,GO:0071986,GO:0071986,GO:0072657,GO:0101003,GO:0150032,GO:1904263,GO:1990877

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LAMTOR1 hsa:55004 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 LAMTOR1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LAMTOR1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 LAMTOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LAMTOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LAMTOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 LAMTOR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000042E1F LAMTOR1 20371350 23446348 23622248 24398324 25416803 mrna cleavage,inhibition clip,clash TarBase
URS0000031E12 LAMTOR1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039607D LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 LAMTOR1 20371350 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD LAMTOR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 LAMTOR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 LAMTOR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 LAMTOR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 LAMTOR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E LAMTOR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 LAMTOR1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TBC1D7 LAMTOR1 25348397 N/A physical interaction ComPPI
BAG3 LAMTOR1 25348397 N/A physical interaction ComPPI
XRCC5 LAMTOR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LAMTOR3 LAMTOR1 22980980 24234451 25348397 25561175 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EEF1A1 LAMTOR1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ATP6AP2 LAMTOR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB9A LAMTOR1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MME LAMTOR1 17342744 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
LIMK1 LAMTOR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DUSP22 LAMTOR1 25348397 N/A physical interaction ComPPI
GNAS LAMTOR1 25348397 N/A physical interaction ComPPI
ELAVL1 LAMTOR1 25348397 N/A physical interaction ComPPI
MTOR LAMTOR1 22980980 24234451 25348397 association cross-linking study ComPPI,IntAct
CAPN1 LAMTOR1 12358155 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
TGOLN2 LAMTOR1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TMEM132A LAMTOR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPTOR LAMTOR1 22980980 24234451 25348397 25561175 association anti tag coimmunoprecipitation,cross-linking study ComPPI,IntAct
RRAGC LAMTOR1 20381137 22424946 22980980 24234451 25348397 25561175 25567906 colocalization,association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
RRAGB LAMTOR1 20381137 22980980 24234451 25348397 25561175 25567906 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGD LAMTOR1 20381137 22424946 24234451 25348397 25561175 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGA LAMTOR1 22980980 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LAMTOR1 GNAS 25348397 N/A physical interaction ComPPI
LAMTOR1 LAMTOR5 22980980 24234451 25348397 25561175 colocalization,association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
LAMTOR1 ZNRF2 25348397 N/A physical interaction ComPPI
ATP6V1B2 LAMTOR1 22980980 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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