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GENE：MAP1LC3C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAP1LC3C
FullNmae microtubule associated protein 1 light chain 3 gamma
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13353
EnsembleID ENSG00000197769
Uniprot Q9BXW4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAP1LC3C ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAP1LC3C ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
MAP1LC3C autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAP1LC3C autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MAP1LC3C GO:0000045,GO:0000421,GO:0000421,GO:0000422,GO:0005515,GO:0005776,GO:0005776,GO:0005776,GO:0005829,GO:0005829,GO:0005874,GO:0006995,GO:0008429,GO:0009267,GO:0012505,GO:0016236,GO:0016236,GO:0031090,GO:0031410,GO:0031625,GO:0031625,GO:0032527,GO:0035973,GO:0036464,GO:0097352,GO:0097352

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MAP1LC3C hsa:440738 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa04140 Autophagy - animal - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa04216 Ferroptosis - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa05131 Shigellosis - Homo sapiens (human)
MAP1LC3C hsa:440738 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NBR1 MAP1LC3C 19250911 23022382 23180781 physical association pull down InnateDB
SQSTM1 MAP1LC3C 19250911 23022382 23180781 physical association pull down InnateDB
CALCOCO2 MAP1LC3C 23022382 23180781 physical association anti tag coimmunoprecipitation,fluorescence polarization spectroscopy,nuclear magnetic resonance,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 MAP1LC3C 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MAP1LC3C 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MAP1LC3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MAP1LC3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 MAP1LC3C 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
TRIM21 MAP1LC3C 25348397 N/A physical interaction ComPPI
LAT MAP1LC3C 25348397 N/A two hybrid ComPPI
TSR2 MAP1LC3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GABARAPL2 MAP1LC3C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF5 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
TNIP1 MAP1LC3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OPTN MAP1LC3C 25348397 N/A physical interaction ComPPI
KBTBD7 MAP1LC3C 20562859 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
NBR1 MAP1LC3C 19250911 20562859 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
CUL3 MAP1LC3C 25348397 N/A physical interaction ComPPI
PRKAR1A MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
UBC MAP1LC3C 25348397 N/A physical interaction ComPPI
RNF123 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
NSMAF MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
SQSTM1 MAP1LC3C 19250911 20562859 24234451 24668264 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
RABGAP1 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
HNRNPA2B1 MAP1LC3C 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LMNB1 MAP1LC3C 24234451 25348397 26524528 N/A pull down,physical interaction ComPPI,IntAct
TFCP2 MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SF3A1 MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
FNBP1 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
GABARAP MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RASSF1 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
TBC1D25 MAP1LC3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAX1BP1 MAP1LC3C 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STK4 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
TP53INP1 MAP1LC3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LACRT MAP1LC3C 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ZNF24 MAP1LC3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MEFV MAP1LC3C 25348397 N/A physical interaction ComPPI
USP11 MAP1LC3C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NEDD4 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
PIK3C3 MAP1LC3C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STK3 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
RB1CC1 MAP1LC3C 20562859 24234451 24290141 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CLINT1 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
PDCD6IP MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
NEK9 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
ULK1 MAP1LC3C 20562859 24234451 24290141 25348397 association,physical association pull down,physical interaction ComPPI,IntAct
PIK3R4 MAP1LC3C 25348397 N/A physical interaction ComPPI
SAFB2 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
CALCOCO2 MAP1LC3C 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GYS1 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
ATG3 MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG7 MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG10 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
GMEB2 MAP1LC3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATG16L1 MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
ACTA2 MAP1LC3C 25348397 N/A physical interaction ComPPI
UBA5 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
ATG4B MAP1LC3C 20562859 24234451 25348397 physical association pull down,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NCOA7 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
DNAAF4 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
HADHB MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
PCM1 MAP1LC3C 24234451 25348397 28712572 physical association anti tag coimmunoprecipitation ComPPI,IntAct
ATG5 MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IPO5 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
FNIP1 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
NIPSNAP2 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
ATG2A MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
ANKFY1 MAP1LC3C 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
KBTBD6 MAP1LC3C 20562859 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
TBC1D15 MAP1LC3C 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
MAP1LC3C ATG13 20562859 24234451 24290141 25348397 association,physical association two hybrid,pull down,surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct
MAP1LC3C WDFY3 24234451 24668264 25348397 association,physical association anti tag coimmunoprecipitation,isothermal titration calorimetry,pull down,physical interaction ComPPI,IntAct
MAP1LC3C WDR81 25348397 N/A physical interaction ComPPI
MAP1LC3C ATG101 20562859 24234451 24290141 25348397 association,physical association pull down,physical interaction ComPPI,IntAct
MAP1LC3C FYCO1 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
MAP1LC3C TECPR2 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
MAP1LC3C TBC1D2B 20562859 24234451 25348397 physical association pull down ComPPI,IntAct
MAP1LC3C APOBEC3B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3C RUFY4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAP1LC3C RHOXF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM72A MAP1LC3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAP1LC3C MAP1LC3C 20562859 24234451 24668264 association,physical association anti tag coimmunoprecipitation,pull down IntAct
TP53INP1 MAP1LC3C 22421968 27898060 stimulant N/A OmniPath
MAP1LC3C NBR1 19250911 20562859 21620860 23022382 27898060 inhibition N/A OmniPath
ATG4B MAP1LC3C 15187094 20562859 27898060 stimulant N/A OmniPath

Visualization










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