GENE：MVB12A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MVB12A |
| FullNmae | multivesicular body subunit 12A |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25153 |
| EnsembleID | ENSG00000141971 |
| Uniprot | Q96EY5 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MVB12A | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MVB12A | GO:0000813,GO:0000813,GO:0000813,GO:0000813,GO:0005515,GO:0005634,GO:0005813,GO:0005829,GO:0005829,GO:0008289,GO:0010008,GO:0010008,GO:0016236,GO:0017124,GO:0019075,GO:0019075,GO:0031902,GO:0031982,GO:0032510,GO:0032801,GO:0036258,GO:0036258,GO:0039702,GO:0042058,GO:0042058,GO:0043130,GO:0043162,GO:0043231,GO:0043328,GO:0046755,GO:0046755,GO:0070062,GO:0090148 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MVB12A | hsa:93343 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | MVB12A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| PRDM14 | MVB12A | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | MVB12A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VPS37C | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| SH3KBP1 | MVB12A | 14525934 16895919 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| CDK5R1 | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| CD2AP | MVB12A | 14525934 16895919 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| GRB2 | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| ARFIP1 | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| CEP55 | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| PDCD6 | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| CIDEB | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| WARS1 | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| MVB12A | APP | 25348397 | N/A | physical interaction | ComPPI |
| MVB12A | LTB4R2 | 25348397 | N/A | physical interaction | ComPPI |
| MVB12A | SMCHD1 | 25348397 | N/A | physical interaction | ComPPI |
| OXTR | MVB12A | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |