GENE：MVB12B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MVB12B |
| FullNmae | multivesicular body subunit 12B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:23368 |
| EnsembleID | ENSG00000196814 |
| Uniprot | Q9H7P6 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MVB12B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| MVB12B | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MVB12B | GO:0000813,GO:0000813,GO:0005515,GO:0005634,GO:0005769,GO:0005770,GO:0005770,GO:0005829,GO:0005886,GO:0008289,GO:0010008,GO:0015031,GO:0019075,GO:0019075,GO:0031902,GO:0031982,GO:0042058,GO:0042058,GO:0043162,GO:0046755,GO:0046755,GO:0070062 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MVB12B | hsa:89853 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | MVB12B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | MVB12B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | MVB12B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | MVB12B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | MVB12B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | MVB12B | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | MVB12B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000070B1D | MVB12B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003804D8 | MVB12B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004407DC | MVB12B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | MVB12B | 21572407 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000022B729 | MVB12B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | MVB12B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CC005 | MVB12B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | MVB12B | 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FEM1B | MVB12B | 25348397 | N/A | physical interaction | ComPPI |
| LNX1 | MVB12B | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| ITM2C | MVB12B | 25348397 | N/A | physical interaction | ComPPI |
| PLCG1 | MVB12B | 25348397 | N/A | physical interaction | ComPPI |