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GENE：PEX5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PEX5
FullNmae peroxisomal biogenesis factor 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9719
EnsembleID ENSG00000139197
Uniprot P50542

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PEX5 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PEX5 GO:0000038,GO:0000268,GO:0000425,GO:0001764,GO:0005052,GO:0005052,GO:0005052,GO:0005515,GO:0005737,GO:0005739,GO:0005777,GO:0005778,GO:0005778,GO:0005778,GO:0005782,GO:0005782,GO:0005794,GO:0005829,GO:0005829,GO:0005829,GO:0006635,GO:0007006,GO:0007029,GO:0016020,GO:0016558,GO:0016558,GO:0016558,GO:0016558,GO:0016560,GO:0016560,GO:0016562,GO:0019899,GO:0021795,GO:0021895,GO:0031267,GO:0031333,GO:0032991,GO:0033328,GO:0034614,GO:0040018,GO:0044721,GO:0044721,GO:0045046,GO:0048468,GO:0050905,GO:0140597,GO:0140597

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PEX5 hsa:5830 path:hsa04146 Peroxisome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SSTR5 PEX5 16012170 23180781 physical association two hybrid,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PEX5 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PEX5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PEX5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PEX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PEX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PEX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PEX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PEX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PEX5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PEX5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000C85B2 PEX5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000096022 PEX5 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ATM PEX5 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
LDHB PEX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TOMM22 PEX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MKRN3 PEX5 25348397 N/A physical interaction ComPPI
FIS1 PEX5 25348397 N/A physical interaction ComPPI
ACOX3 PEX5 25348397 N/A physical interaction ComPPI
GSK3B PEX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PEX10 PEX5 10837480 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PEX2 PEX5 25348397 N/A physical interaction ComPPI
ACOX1 PEX5 25348397 N/A physical interaction ComPPI
UBB PEX5 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
UBC PEX5 17726030 21980954 25348397 27898060 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,OmniPath
RPS27A PEX5 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
UBA52 PEX5 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
SQSTM1 PEX5 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
ATM PEX5 10567403 14525934 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
XPO1 PEX5 25348397 N/A physical interaction ComPPI
PDZK1 PEX5 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SCP2 PEX5 25348397 N/A physical interaction ComPPI
EHHADH PEX5 25348397 N/A physical interaction ComPPI
NOS2 PEX5 25348397 N/A physical interaction ComPPI
PEX12 PEX5 10562279 10837480 11370741 12096124 12456682 12667447 14525934 15456864 16849337 22002062 24234451 25162638 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,filter binding,physical interaction,two hybrid ComPPI,HPRD,IntAct,OmniPath
PEX13 PEX5 10087260 11071920 11101511 11865044 12453410 12876220 14525934 15456864 16849337 19584060 20655618 22002062 25348397 27898060 8858165 8858166 8858167 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
PEX14 PEX5 10022913 10087260 10212238 10837480 11865044 12096124 12667447 12876220 14525934 15456864 15949802 16107331 16849337 19197237 19584060 21525035 22002062 22021076 22375831 24234451 24879895 25348397 27898060 9094717 9312008 colocalization,association,physical association two hybrid,experimental interaction detection,isothermal titration calorimetry,molecular sieving,nuclear magnetic resonance,peptide array,pull down,ubiquitin reconstruction,physical interaction,fluorescence microscopy ComPPI,HPRD,IntAct,OmniPath
AP2M1 PEX5 25348397 N/A physical interaction ComPPI
PECR PEX5 25348397 N/A physical interaction ComPPI
PEX7 PEX5 10087260 11546814 11865044 14525934 22002062 23297417 24879895 25348397 27898060 8670791 9094717 9425153 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,OmniPath
POT1 PEX5 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TINF2 PEX5 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
BRCA1 PEX5 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TOMM20 PEX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
S100A6 PEX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNUPN PEX5 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AGPS PEX5 25348397 N/A physical interaction ComPPI
GNPAT PEX5 25348397 N/A physical interaction ComPPI
RPL14 PEX5 25348397 N/A physical interaction ComPPI
TOMM7 PEX5 25348397 N/A physical interaction ComPPI
ACD PEX5 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
BAAT PEX5 25348397 N/A physical interaction ComPPI
CAT PEX5 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MYH9 PEX5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AGXT PEX5 14525934 15911627 22529745 25348397 27898060 N/A experimental interaction detection,isothermal titration calorimetry,molecular sieving,static light scattering,x-ray crystallography,physical interaction ComPPI,HPRD,OmniPath
PRR13 PEX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
USP2 PEX5 25348397 N/A physical interaction ComPPI
NUDT3 PEX5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CCDC14 PEX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ECH1 PEX5 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIRT3 PEX5 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HACL1 PEX5 25348397 N/A physical interaction ComPPI
IDH1 PEX5 25348397 N/A physical interaction ComPPI
EPHX2 PEX5 25348397 N/A physical interaction ComPPI
PLGRKT PEX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 PEX5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DDO PEX5 14525934 20178365 25348397 27898060 9820813 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
HMGCL PEX5 25348397 N/A physical interaction ComPPI
PRDX5 PEX5 25348397 N/A physical interaction ComPPI
PIPOX PEX5 25348397 N/A physical interaction ComPPI
DAO PEX5 25348397 N/A physical interaction ComPPI
HSD17B4 PEX5 25348397 N/A physical interaction ComPPI
SLX4 PEX5 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IDE PEX5 25348397 N/A physical interaction ComPPI
HOXA7 PEX5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PDZK1P1 PEX5 25348397 N/A physical interaction ComPPI
PEX5 USP9X 22371489 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PEX5 ACOX2 25348397 N/A physical interaction ComPPI
PEX5 ECI2 25348397 N/A physical interaction ComPPI
PEX5 DECR2 25348397 N/A physical interaction ComPPI
PEX5 AMACR 25348397 N/A physical interaction ComPPI
PEX5 CRAT 25348397 N/A physical interaction ComPPI
PEX5 CROT 25348397 N/A physical interaction ComPPI
PEX5 ACOT2 25348397 N/A physical interaction ComPPI
PEX5 HAO1 25348397 N/A physical interaction ComPPI
PEX5 HAO2 25348397 N/A physical interaction ComPPI
PEX5 SLC27A2 25348397 N/A physical interaction ComPPI
PEX5 GSTK1 25348397 N/A physical interaction ComPPI
PEX5 MLYCD 25348397 N/A physical interaction ComPPI
PEX5 NUDT7 25348397 N/A physical interaction ComPPI
PEX5 LONP2 25348397 N/A physical interaction ComPPI
PEX5 NUDT19 25348397 N/A physical interaction ComPPI
PEX5 DHRS4 25348397 N/A physical interaction ComPPI
PEX5 MPV17 25348397 N/A physical interaction ComPPI
PEX5 ACAD11 25348397 N/A physical interaction ComPPI
PEX5 HSDL2 25348397 N/A physical interaction ComPPI
PEX5 ZADH2 25348397 N/A physical interaction ComPPI
PEX5 TYSND1 25348397 N/A physical interaction ComPPI
PEX5 RANBP6 25348397 N/A physical interaction ComPPI
PEX5 TM6SF1 25348397 N/A physical interaction ComPPI
PEX5 CAPRIN2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PEX5 GDPD5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PEX5 ZNF772 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PEX5 MOV10 25348397 N/A physical interaction ComPPI
PEX5 NXF1 25348397 N/A physical interaction ComPPI
PEX5 CCDC8 25348397 N/A physical interaction ComPPI
PEX5 ACAA1 25348397 N/A physical interaction ComPPI
PEX5 IQCN 25348397 N/A physical interaction ComPPI
PEX5 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ACOT8 PEX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NEU2 PEX5 25348397 N/A physical interaction ComPPI
PEX5 SCARB1 14525934 14652019 27898060 N/A experimental interaction detection HPRD,OmniPath
SSTR5 PEX5 14525934 16012170 N/A experimental interaction detection,two hybrid HPRD
PEX5 HSPA1A 11415446 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
PLEC PEX5 24234451 30021884 physical association cross-linking study IntAct
PEX5 SLC7A2 27898060 7628448 N/A N/A OmniPath

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