GENE:PLIN2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PLIN2 |
| FullNmae | perilipin 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:248 |
| EnsembleID | ENSG00000147872 |
| Uniprot | Q99541 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PLIN2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PLIN2 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PLIN2 | GO:0005515,GO:0005576,GO:0005634,GO:0005783,GO:0005811,GO:0005811,GO:0005829,GO:0005886,GO:0009410,GO:0010890,GO:0014070,GO:0015909,GO:0019915,GO:0019915,GO:0042149,GO:1905691 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PLIN2 | hsa:123 | path:hsa03320 | PPAR signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PLIN2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | PLIN2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | PLIN2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | PLIN2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | PLIN2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | PLIN2 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| SMARCA4 | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | PLIN2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARA | PLIN2 | 17150915 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARG | PLIN2 | 11420178 16403437 17322100 19571381 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003BBF48 | PLIN2 | 25416803 27591428 | mrna cleavage,inhibition | experimental interaction detection,quantitative reverse transcription pcr | TarBase |
| URS0000065D58 | PLIN2 | 25416803 27591428 | mrna cleavage,inhibition | experimental interaction detection,quantitative reverse transcription pcr | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAPK10 | PLIN2 | 18624398 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| POGZ | PLIN2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| LIPE | PLIN2 | 25348397 | N/A | physical interaction | ComPPI |
| APOB | PLIN2 | 25348397 | N/A | physical interaction | ComPPI |
| ARF1 | PLIN2 | 14525934 15336557 27898060 | N/A | experimental interaction detection,two hybrid | HPRD,OmniPath |
