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GENE：RPS6KB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPS6KB1
FullNmae ribosomal protein S6 kinase B1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10436
EnsembleID ENSG00000108443
Uniprot P23443

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPS6KB1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPS6KB1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPS6KB1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPS6KB1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPS6KB1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RPS6KB1 GO:0000082,GO:0001662,GO:0003009,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004711,GO:0004712,GO:0005515,GO:0005524,GO:0005654,GO:0005654,GO:0005737,GO:0005739,GO:0005741,GO:0005829,GO:0006915,GO:0007165,GO:0007281,GO:0007616,GO:0009410,GO:0009612,GO:0009636,GO:0009749,GO:0009986,GO:0014732,GO:0014878,GO:0014911,GO:0016477,GO:0018105,GO:0018105,GO:0030165,GO:0031667,GO:0031670,GO:0031929,GO:0031929,GO:0032496,GO:0032869,GO:0033574,GO:0033762,GO:0034612,GO:0042277,GO:0042802,GO:0043005,GO:0043066,GO:0043201,GO:0043491,GO:0044539,GO:0045471,GO:0045727,GO:0045931,GO:0045948,GO:0045948,GO:0046324,GO:0046627,GO:0048015,GO:0048471,GO:0048633,GO:0048661,GO:0050804,GO:0051721,GO:0071346,GO:0071363,GO:0071549,GO:0098794,GO:0098978,GO:0106310,GO:1904263,GO:2001237

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RPS6KB1 hsa:6198 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa01522 Endocrine resistance - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04140 Autophagy - animal - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04213 Longevity regulating pathway - multiple species - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04714 Thermogenesis - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa04931 Insulin resistance - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05131 Shigellosis - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05200 Pathways in cancer - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05210 Colorectal cancer - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05221 Acute myeloid leukemia - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05224 Breast cancer - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05226 Gastric cancer - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)
RPS6KB1 hsa:6198 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RPS6KB1 PDCD4 17053147 23180781 phosphorylation reaction,ubiquitination reaction enzymatic study,protein kinase assay InnateDB
RPS6KB1 RPS6KB1 12807916 15905173 16914728 17053147 23180781 26467481 9312143 phosphorylation reaction,ubiquitination reaction,up-regulates activity,down-regulates activity enzymatic study InnateDB,Signor
RPS6KB1 MTOR 15760907 23180781 physical association anti tag coimmunoprecipitation InnateDB
POLDIP3 RPS6KB1 18423201 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF3B RPS6KB1 16286006 23180781 physical association anti tag coimmunoprecipitation InnateDB
RPS6KB1 PDK1 16286006 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF4 RPS6KB1 12801526 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
RPS6KB1 PRKCZ 16931574 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP RPS6KB1 21832049 23180781 physical association protein array InnateDB
RPS6KB1 TERT 15843522 23180781 physical association anti tag coimmunoprecipitation InnateDB
AKT1 RPS6KB1 11943559 15149849 21071413 23331499 stimulation N/A SignaLink,SignaLink
MAPK8 RPS6KB1 23816567 phosphorylation reaction,stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
EIF4EBP1 RPS6KB1 20005715 interaction type N/A PSP
RPTOR RPS6KB1 20005715 interaction type N/A PSP
PPP1R9B RPS6KB1 20005715 interaction type N/A PSP,SignaLink
RPS6 RPS6KB1 20005715 interaction type N/A PSP
RPTOR RPS6KB1 12150926 12150926 12604610 12604610 16183647 18988627 20005715 20005715 21071413 N/A N/A SignaLink
EIF4EBP1 RPS6KB1 20005715 20005715 N/A N/A SignaLink
RPS6 RPS6KB1 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 RPS6KB1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MYC RPS6KB1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA RPS6KB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RPS6KB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RPS6KB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RPS6KB1 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F2 RPS6KB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 RPS6KB1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 RPS6KB1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 RPS6KB1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D RPS6KB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D RPS6KB1 24398324 25416803 26080838 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunocytochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A RPS6KB1 24398324 25416803 26238185 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002C02E4 RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 RPS6KB1 24157791 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000040780F RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 RPS6KB1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 RPS6KB1 25416803 26701625 28260062 mrna cleavage,inhibition quantitative reverse transcription pcr,clip TarBase
URS0000171525 RPS6KB1 25416803 25985365 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001D4A78 RPS6KB1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F14FE RPS6KB1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 RPS6KB1 22135298 phosphorylation N/A PhosphoSite
PDPK1 RPS6KB1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPK1 RPS6KB1 22135298 phosphorylation N/A PhosphoSite
MTOR RPS6KB1 22135298 phosphorylation N/A PhosphoSite
PIK3CA RPS6KB1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
NEK6 RPS6KB1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 BACH2 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 IRS1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 TARBP2 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 MTOR 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 FMR1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 NDRG2 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 RPS6 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RPS6KB1 GSK3B 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 PDCD4 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 TP63 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 TRIB2 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 DEPTOR 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 RPS6KB1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 EEF2K 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RPS6KB1 ESR1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 LTC4S 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 MXD1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 URI1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 CAD 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 NCBP1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 CCT2 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 PIP5K1C 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 GLI1 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 RICTOR 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RPS6KB1 EIF4B 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 H2BC3 22135298 phosphorylation N/A PhosphoSite
RPS6KB1 POLDIP3 22135298 phosphorylation N/A PhosphoSite
EEF2K RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 PIK3CA 25361965 interaction type N/A PTMCode2
RPS6KB1 AKT1 25361965 interaction type N/A PTMCode2
AKT1 RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 RPTOR 25361965 interaction type N/A PTMCode2
RPTOR RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 TERT 25361965 interaction type N/A PTMCode2
TERT RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 CDC42 25361965 interaction type N/A PTMCode2
CDC42 RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 EIF4EBP1 25361965 interaction type N/A PTMCode2
EIF4EBP1 RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 PDPK1 25361965 interaction type N/A PTMCode2
RICTOR RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 EIF3B 25361965 interaction type N/A PTMCode2
EIF3B RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6 RPS6KB1 25361965 interaction type N/A PTMCode2
RPS6KB1 PPP2CA 25361965 interaction type N/A PTMCode2
PPP2CA RPS6KB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 RPS6KB1 14525934 19168580 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK9 RPS6KB1 11279232 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CDC42 RPS6KB1 11438723 14525934 24234451 25348397 physical association beta lactamase complementation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
EIF3H RPS6KB1 25348397 N/A physical interaction ComPPI
STAT1 RPS6KB1 25348397 N/A physical interaction ComPPI
UBL4A RPS6KB1 25348397 N/A physical interaction ComPPI
RAC1 RPS6KB1 11438723 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DPPA4 RPS6KB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSP90AB1 RPS6KB1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PPP1R9A RPS6KB1 12052877 14525934 25348397 9653190 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PAK1 RPS6KB1 23175184 24234451 25348397 association pull down ComPPI,IntAct
MAPK1 RPS6KB1 11279232 12054624 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
BTK RPS6KB1 25348397 N/A physical interaction ComPPI
SYK RPS6KB1 25348397 N/A physical interaction ComPPI
MAPK8 RPS6KB1 11279232 14525934 21988832 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
LYN RPS6KB1 25348397 N/A physical interaction ComPPI
SRC RPS6KB1 25348397 N/A physical interaction ComPPI
NFATC1 RPS6KB1 25348397 N/A physical interaction ComPPI
MAPK3 RPS6KB1 11279232 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EP300 RPS6KB1 25348397 N/A physical interaction ComPPI
KAT2B RPS6KB1 25348397 N/A physical interaction ComPPI
GLI1 RPS6KB1 22439934 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RBX1 RPS6KB1 25348397 N/A physical interaction ComPPI
IRS2 RPS6KB1 25348397 N/A physical interaction ComPPI
PIK3CA RPS6KB1 11279232 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HSP90AA1 RPS6KB1 25348397 N/A physical interaction ComPPI
PLD2 RPS6KB1 25348397 N/A physical interaction ComPPI
NR1I2 RPS6KB1 25348397 N/A physical interaction ComPPI
CLEC3B RPS6KB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDPK1 RPS6KB1 10601311 11438723 14525934 24234451 25348397 9271440 9427642 9445476 physical association beta lactamase complementation,experimental interaction detection,in vitro,in vivo ComPPI,HPRD,IntAct
MAPT RPS6KB1 25348397 N/A anti bait coimmunoprecipitation,physical interaction,in vitro ComPPI
CSNK2A1 RPS6KB1 25348397 N/A physical interaction ComPPI
HNRNPL RPS6KB1 25348397 N/A physical interaction ComPPI
EIF4EBP1 RPS6KB1 11438723 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PPP1R9B RPS6KB1 14525934 25348397 9653190 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PRKCZ RPS6KB1 25348397 N/A physical interaction ComPPI
TERT RPS6KB1 25348397 N/A physical interaction,in vivo ComPPI
PPP2CA RPS6KB1 10200280 11438723 14525934 16109716 16899564 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SQSTM1 RPS6KB1 25348397 N/A physical interaction ComPPI
EIF3C RPS6KB1 25348397 N/A physical interaction ComPPI
EIF3F RPS6KB1 25348397 N/A physical interaction ComPPI
XPO1 RPS6KB1 14525934 16895915 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RPS6 RPS6KB1 11438723 14525934 16810323 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RPS6KB1 NCBP1 10973943 14525934 18423201 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RPS6KB1 MTOR 11279232 11914378 12604610 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RPS6KB1 STK11 11297520 11853558 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
RPS6KB1 TRAF4 12801526 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RPS6KB1 NEK6 11516946 12023960 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RPS6KB1 EEF2K 11171059 11500364 14525934 14709557 15024086 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RPS6KB1 POLDIP3 14525934 15341740 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RPS6KB1 COASY 14525934 15589845 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,surface plasmon resonance,physical interaction,in vivo ComPPI,HPRD,IntAct
RPS6KB1 EIF4B 14525934 16763566 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RPS6KB1 RPTOR 12150926 12604610 14525934 16183647 24234451 25348397 26348909 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
RPS6KB1 PDK1 11279232 14525934 17110931 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
RPS6KB1 CSNK2B 14525934 16895915 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RPS6KB1 AKT1 11438723 14525934 24234451 25241761 25348397 physical association beta lactamase complementation,experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
RPS6KB1 PPP2R2A 25348397 N/A physical interaction ComPPI
RPS6KB1 ACTA1 25348397 N/A physical interaction ComPPI
RPS6KB1 EIF3B 18423201 21986499 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6KB1 RICTOR 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
RPS6KB1 MDM2 25348397 N/A physical interaction ComPPI
RPS6KB1 NEDD4 25348397 N/A physical interaction ComPPI
RPS6KB1 MXD1 18451027 24234451 25348397 N/A physical interaction,protein kinase assay ComPPI,IntAct
RPS6KB1 ELAVL1 25348397 N/A physical interaction ComPPI
RPS6KB1 MAPKAP1 25348397 N/A physical interaction ComPPI
RPS6KB1 IRS1 25348397 N/A physical interaction ComPPI
RPS6KB1 APP 25348397 N/A physical interaction ComPPI
RPS6KB1 HSP90AA2P 25348397 N/A physical interaction ComPPI
RPS6KB1 URI1 25348397 N/A physical interaction ComPPI
RPS6KB1 KIR3DL1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPS6KB1 TRIB2 25348397 N/A physical interaction ComPPI
RPS6KB1 HTT 25348397 N/A physical interaction ComPPI
RPS6KB1 EIF4E 18423201 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6KB1 RHEB 25348397 N/A physical interaction ComPPI
RPS6KB1 PPP5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6KB1 DEPTOR 25348397 N/A physical interaction ComPPI
RPS6KB1 PIP4K2A 25348397 N/A physical interaction ComPPI
RPS6KB1 TRIM25 25348397 N/A physical interaction ComPPI
RPS6KB1 PPP2R2B 21075311 24234451 25348397 association,physical association anti tag coimmunoprecipitation ComPPI,IntAct
RPS6KB1 PHLPP1 21986499 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPS6KB1 PHLPP2 21986499 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPS6KB1 IER5 24234451 25348397 26496226 physical association pull down ComPPI,IntAct
CDK1 RPS6KB1 12586835 14525934 9271440 N/A experimental interaction detection HPRD
YES1 RPS6KB1 11914378 27898060 9271440 9465032 N/A N/A OmniPath
RPS6KB1 SREBF1 20670887 27898060 stimulant N/A OmniPath
RPS6KB1 STK11 11297520 11853558 25241761 27898060 N/A N/A OmniPath
RPS6KB1 MDM2 20657550 27898060 inhibition,stimulant N/A OmniPath
APP RPS6KB1 21832049 27898060 N/A N/A OmniPath
RPS6KB1 APP 21832049 27898060 N/A N/A OmniPath
RPS6KB1 SLC6A3 15024426 27898060 N/A N/A OmniPath
RPS6KB1 ESR1 27898060 7838153 stimulant N/A OmniPath
PDPK1 RPS6KB1 10601311 11438723 11914378 12023960 12183455 14993219 15208671 15388791 17347671 17848913 19864428 21087210 21986499 27898060 9271440 9427642 9445476 stimulant N/A OmniPath
RPS6KB1 TP63 18769144 27898060 inhibition N/A OmniPath
AKT1 RPS6KB1 11438723 11943559 15149849 1514985 25241761 27898060 stimulant N/A OmniPath
RPS6KB1 IRS1 14769130 15306821 15364919 15604215 16020478 16914728 17081983 17277771 17640984 18220336 18952604 19369195 20594869 21850561 23045529 26297026 27898060 9312143 inhibition,stimulant N/A OmniPath
RPS6KB1 RICTOR 15809305 19995915 25241761 27898060 inhibition,stimulant N/A OmniPath
PDK1 RPS6KB1 11279232 16286006 17110931 18669648 20068231 27898060 stimulant N/A OmniPath
MAPK3 RPS6KB1 11279232 14967450 15774499 27898060 stimulant N/A OmniPath
PIK3CA RPS6KB1 11279232 18669648 20068231 27898060 stimulant N/A OmniPath
PRKCZ RPS6KB1 16931574 27898060 stimulant N/A OmniPath
RPS6KB1 FMR1 12446764 16922515 17376973 22080836 24180586 24806451 27898060 N/A N/A OmniPath
CDK1 RPS6KB1 11705993 11914378 12586835 14993219 15774499 18669648 27898060 9271440 stimulant N/A OmniPath
PHLPP1 RPS6KB1 21986499 27898060 inhibition N/A OmniPath
RPS6KB1 GLI1 22439934 27898060 stimulant N/A OmniPath
MAPK1 RPS6KB1 11145615 11279232 11684675 11705993 11867620 11872747 12036952 12054624 12138083 12183455 12429015 12555062 12556562 12586835 12711631 12740386 12935893 14967450 14993219 15028555 15070696 15208671 15235105 15304500 15471950 15576463 15632201 15705590 15774499 15798205 15809305 15843586 16322256 16364302 16397245 17121928 17597835 18250445 19085255 20054340 21035469 21402888 21561857 27898060 7489717 7545671 9218810 9271440 9722592 stimulant N/A OmniPath
RPS6KB1 TRAF4 12801526 27898060 N/A N/A OmniPath
PPP2CA RPS6KB1 10200280 11124802 11438723 16109716 16899564 27898060 2826472 inhibition N/A OmniPath
RPS6KB1 TLR3 12509442 27898060 N/A N/A OmniPath
RPS6KB1 RPS6 11438723 15358595 15471950 15809305 16810323 17360704 17693255 18423201 1939282 20227368 20464435 21460630 23899556 24396066 27898060 7705100 8440735 stimulant N/A OmniPath
RPS6KB1 MTOR 10567225 10567431 10579915 10910062 10971657 11279232 11914378 12023960 12150925 12150926 12370290 12586835 12604610 12718876 12782654 12807916 14560963 14679009 15066126 15388791 15718470 15760907 15809305 15854902 15896331 15899889 15905173 16099428 16183647 16922504 17386266 18505677 18669648 18691976 19664994 20068231 22544753 27898060 9271440 9465032 stimulant N/A OmniPath
MTOR RPS6KB1 10567225 10567431 10579915 10910062 10971657 11279232 11500364 11914378 12023960 12150925 12150926 12370290 12586835 12604610 12718876 12782654 12807916 14560963 14679009 15066126 15388791 15718470 15760907 15809305 15854902 15896331 15899889 15905173 16099428 16183647 16922504 17386266 18326039 18505677 18669648 18691976 19570988 19664994 20068231 22544753 25936802 27898060 9271440 9465032 stimulant N/A OmniPath
RPS6KB1 EIF4B 15071500 16083285 16763566 17924679 18707149 19413330 19651622 19664995 20068231 27898060 stimulant N/A OmniPath
RPS6KB1 HSPB1 19593530 27898060 inhibition N/A OmniPath
PPP2R5C RPS6KB1 20444422 27898060 inhibition N/A OmniPath
RPS6KB1 CAD 1359877 23429703 27898060 stimulant N/A OmniPath
RPS6KB1 MXD1 18451027 27898060 inhibition N/A OmniPath
RPS6KB1 CCT2 19332537 25342745 27898060 N/A N/A OmniPath
RPS6KB1 EIF3B 16286006 18423201 21986499 24396066 27898060 N/A N/A OmniPath
RPS6KB1 POLDIP3 15341740 16984396 18423201 27898060 N/A N/A OmniPath
RPS6KB1 PFKFB2 27898060 2846551 9211863 stimulant N/A OmniPath
PHLPP2 RPS6KB1 21986499 27898060 inhibition N/A OmniPath
RPS6KB1 PDCD4 16357133 17053147 18296647 27898060 inhibition N/A OmniPath
RPS6KB1 EEF2K 11171059 11500364 12171600 14709557 15024086 16858730 23182879 25182533 27898060 inhibition N/A OmniPath
RPS6KB1 CREM 27898060 7923380 stimulant N/A OmniPath
RPS6KB1 DEPTOR 19446321 22017876 27898060 inhibition N/A OmniPath
PPP2CB RPS6KB1 10200280 11124802 27898060 2826472 inhibition N/A OmniPath
RPS6KB1 NCBP1 10973943 18669648 19690332 27898060 N/A N/A OmniPath
RPS6KB1 BACH2 17018862 27898060 N/A N/A OmniPath
RPS6KB1 TRIB2 24089522 27898060 N/A N/A OmniPath
RPS6KB1 URI1 17936702 21397856 27898060 N/A N/A OmniPath

Visualization










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