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GENE：TOMM40

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TOMM40
FullNmae translocase of outer mitochondrial membrane 40
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18001
EnsembleID ENSG00000130204
Uniprot O96008

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TOMM40 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TOMM40 GO:0005515,GO:0005739,GO:0005741,GO:0005741,GO:0005741,GO:0005742,GO:0005742,GO:0005743,GO:0005829,GO:0006626,GO:0006626,GO:0006626,GO:0006811,GO:0008320,GO:0008320,GO:0008320,GO:0015288,GO:0016020,GO:0030150,GO:0044233,GO:0045040,GO:0046930

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TOMM40 hsa:10452 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
TOMM40 hsa:10452 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TOMM40 hsa:10452 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TOMM40 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TOMM40 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TOMM40 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TOMM40 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 TOMM40 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 TOMM40 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE TOMM40 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D TOMM40 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005FDE70 TOMM40 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F TOMM40 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B TOMM40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D TOMM40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A TOMM40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AAAFF TOMM40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 TOMM40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 TOMM40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 TOMM40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005A8A8D TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000033B91D TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002373FD TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005ACA7C TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000582627 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075BC91 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003758F0 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023F008 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002F0130 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075E538 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004929F1 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 TOMM40 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TOMM40 BAX 25361965 interaction type N/A PTMCode2
BAX TOMM40 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FARS2 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SNRPC TOMM40 25348397 N/A physical interaction ComPPI
CHCHD3 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YJU2 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHCHD2 TOMM40 25348397 N/A physical interaction ComPPI
COX5B TOMM40 25348397 N/A physical interaction ComPPI
TAX1BP3 TOMM40 25348397 N/A physical interaction ComPPI
TOMM22 TOMM40 11276259 11866524 12198123 1327874 15644312 17635912 18706915 21215441 21825073 21896724 22280891 22939629 23283984 24234451 25348397 27898060 8641278 8754801 9217162 9774667 physical association physical interaction,blue native page ComPPI,IntAct,OmniPath
PSMD7 TOMM40 25348397 N/A physical interaction ComPPI
FOXB1 TOMM40 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FKBP1A TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FIS1 TOMM40 25348397 N/A physical interaction ComPPI
RNF5 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDUFAF4 TOMM40 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
SAMM50 TOMM40 15644312 18358813 21680715 22939629 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SLAMF1 TOMM40 25348397 N/A physical interaction ComPPI
SFPQ TOMM40 25348397 N/A physical interaction ComPPI
VAPA TOMM40 25348397 N/A physical interaction ComPPI
SLC9A3R2 TOMM40 25348397 N/A physical interaction ComPPI
ABCD3 TOMM40 25348397 N/A physical interaction ComPPI
SERPINH1 TOMM40 25348397 N/A physical interaction ComPPI
DLD TOMM40 25348397 N/A physical interaction ComPPI
HSP90AA1 TOMM40 25348397 N/A physical interaction ComPPI
FMNL1 TOMM40 25348397 N/A physical interaction ComPPI
LAMTOR3 TOMM40 25348397 N/A physical interaction ComPPI
C1QBP TOMM40 25348397 N/A physical interaction ComPPI
VDAC1 TOMM40 25348397 N/A physical interaction ComPPI
PDHA1 TOMM40 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NOS1AP TOMM40 25348397 N/A physical interaction ComPPI
QARS1 TOMM40 25348397 N/A physical interaction ComPPI
VDAC2 TOMM40 25348397 N/A physical interaction ComPPI
AP2B1 TOMM40 25348397 N/A physical interaction ComPPI
ATP1B1 TOMM40 25348397 N/A physical interaction ComPPI
ANXA11 TOMM40 25348397 N/A physical interaction ComPPI
ACAA2 TOMM40 25348397 N/A physical interaction ComPPI
PHB2 TOMM40 25348397 N/A physical interaction ComPPI
HSPA4 TOMM40 25348397 N/A physical interaction ComPPI
FUBP1 TOMM40 25348397 N/A physical interaction ComPPI
UBE2A TOMM40 25348397 N/A physical interaction ComPPI
SF1 TOMM40 25348397 N/A physical interaction ComPPI
BAK1 TOMM40 25348397 N/A physical interaction ComPPI
ATP2B1 TOMM40 25348397 N/A physical interaction ComPPI
LAMA1 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB1B TOMM40 25348397 N/A physical interaction ComPPI
PRKN TOMM40 25348397 N/A physical interaction ComPPI
BAX TOMM40 25348397 N/A physical interaction ComPPI
DUSP22 TOMM40 25348397 N/A physical interaction ComPPI
TIAL1 TOMM40 25348397 N/A physical interaction ComPPI
IMMT TOMM40 25348397 N/A physical interaction ComPPI
SRP9 TOMM40 25348397 N/A physical interaction ComPPI
STUB1 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM20 TOMM40 25348397 N/A physical interaction ComPPI
EIF3A TOMM40 25348397 N/A physical interaction ComPPI
EEF2 TOMM40 25348397 N/A physical interaction ComPPI
CAB39 TOMM40 25348397 N/A physical interaction ComPPI
WNT4 TOMM40 25348397 N/A physical interaction ComPPI
BAG2 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FAF2 TOMM40 25348397 N/A physical interaction ComPPI
RMDN3 TOMM40 25348397 N/A physical interaction ComPPI
NUP58 TOMM40 25348397 N/A physical interaction ComPPI
TOMM7 TOMM40 12198123 14525934 24234451 25348397 physical association experimental interaction detection,physical interaction,blue native page,in vitro,in vivo ComPPI,HPRD,IntAct
MTX1 TOMM40 25348397 N/A physical interaction ComPPI
LYPD3 TOMM40 25348397 N/A physical interaction ComPPI
TIMM50 TOMM40 25348397 N/A physical interaction ComPPI
TOMM40 TOMM70 1327874 17978093 21825073 25348397 27898060 8119994 9217162 9774667 N/A physical interaction ComPPI,OmniPath
TOMM40 NIPBL 25348397 N/A physical interaction ComPPI
TOMM40 ABCB6 25348397 N/A physical interaction ComPPI
TOMM40 SRPRB 25348397 N/A physical interaction ComPPI
TOMM40 OXA1L 25348397 N/A physical interaction ComPPI
TOMM40 SDHB 25348397 N/A physical interaction ComPPI
TOMM40 SEPTIN11 25348397 N/A physical interaction ComPPI
TOMM40 SBDS 25348397 N/A physical interaction ComPPI
TOMM40 FLOT2 25348397 N/A physical interaction ComPPI
TOMM40 MRPL55 25348397 N/A physical interaction ComPPI
TOMM40 NDUFA7 25348397 N/A physical interaction ComPPI
TOMM40 CPT1A 25348397 N/A physical interaction ComPPI
TOMM40 ALDH5A1 25348397 N/A physical interaction ComPPI
TOMM40 PRDX5 25348397 N/A physical interaction ComPPI
TOMM40 UBAP2 25348397 N/A physical interaction ComPPI
TOMM40 TAGLN2 25348397 N/A physical interaction ComPPI
TOMM40 HSP90AA2P 25348397 N/A physical interaction ComPPI
TOMM40 UBAC2 25348397 N/A physical interaction ComPPI
TOMM40 TRABD 25348397 N/A physical interaction ComPPI
TOMM40 LRRTM2 25348397 N/A physical interaction ComPPI
TOMM40 KLRF1 25348397 N/A physical interaction ComPPI
TOMM40 LDLRAD4 25348397 N/A physical interaction ComPPI
TOMM40 AIFM1 24234451 25348397 29568061 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TOMM40 CISD1 25348397 N/A physical interaction ComPPI
TOMM40 CPT2 25348397 N/A physical interaction ComPPI
TOMM40 CYC1 25348397 N/A physical interaction ComPPI
TOMM40 MTCH1 25348397 N/A physical interaction ComPPI
TOMM40 MTCH2 25348397 N/A physical interaction ComPPI
TOMM40 NDUFA2 25348397 N/A physical interaction ComPPI
TOMM40 NDUFB8 25348397 N/A physical interaction ComPPI
TOMM40 NDUFS1 25348397 N/A physical interaction ComPPI
TOMM40 NDUFV1 25348397 N/A physical interaction ComPPI
TOMM40 PRCP 25348397 N/A physical interaction ComPPI
TOMM40 RAB1C 25348397 N/A physical interaction ComPPI
TOMM40 SGPL1 25348397 N/A physical interaction ComPPI
TOMM40 SLC25A3 25348397 N/A physical interaction ComPPI
TOMM40 ATP1B3 25348397 N/A physical interaction ComPPI
TOMM40 CAPZB 25348397 N/A physical interaction ComPPI
TOMM40 GSR 25348397 N/A physical interaction ComPPI
TOMM40 HADHA 25348397 N/A physical interaction ComPPI
TOMM40 HMGCL 25348397 N/A physical interaction ComPPI
TOMM40 HSD17B10 25348397 N/A physical interaction ComPPI
TOMM40 VDAC3 25348397 N/A physical interaction ComPPI
TOMM40 ATP5ME 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM40 ITIH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM40 CEPT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM40 SLC35F6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM40 PHACTR4 25348397 N/A physical interaction ComPPI
TOMM40 TUBB6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM40 FOXA3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TOMM40 FOXI1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TOMM40 FOXJ2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TOMM40 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TOMM40 COQ9 25348397 N/A physical interaction ComPPI
TOMM40 NDUFA4 25348397 N/A physical interaction ComPPI
TOMM40 OCIAD1 25348397 N/A physical interaction ComPPI
TOMM40 NCR3LG1 25348397 N/A physical interaction ComPPI
TOMM40 KRBA1 25348397 N/A physical interaction ComPPI
TOMM40 FOXRED2 25348397 N/A physical interaction ComPPI
TOMM40 CYP2C9 25348397 N/A physical interaction ComPPI
TOMM40 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TOMM40 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
TOMM40 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
TOMM40 SHLD3 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
TOMM40 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PLGRKT TOMM40 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 TOMM40 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PINK1 TOMM40 25348397 N/A physical interaction ComPPI
DUSP21 TOMM40 25348397 N/A physical interaction ComPPI
TOMM40 ARFIP2 11266446 17978093 27898060 9217162 N/A N/A OmniPath

Visualization










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