Gene Information gene info

  1. Home

GENE：TOMM70

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TOMM70
FullNmae translocase of outer mitochondrial membrane 70
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11985
EnsembleID ENSG00000154174
Uniprot O94826

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TOMM70 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TOMM70 GO:0002218,GO:0002230,GO:0005515,GO:0005739,GO:0005741,GO:0005741,GO:0005742,GO:0005742,GO:0006626,GO:0006626,GO:0008320,GO:0008320,GO:0008320,GO:0016020,GO:0030150,GO:0030150,GO:0030943,GO:0030943,GO:0031966,GO:0032728,GO:0042981,GO:0045039,GO:0045039,GO:0045040,GO:0060090,GO:0061052,GO:0070062,GO:0097068,GO:0098586,GO:1903955

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TOMM70 hsa:9868 path:hsa04137 Mitophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TOMM70 MAVS 20628368 23180781 physical association anti tag coimmunoprecipitation InnateDB
HSP90AA1 TOMM70 20628368 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
IRAK1 TOMM70 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TOMM70 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GABPA TOMM70 17167546 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
YBX1 TOMM70 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA TOMM70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TOMM70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TOMM70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TOMM70 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 TOMM70 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000148B91 TOMM70 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000008A99 TOMM70 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 TOMM70 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC TOMM70 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C TOMM70 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 TOMM70 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D TOMM70 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 TOMM70 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003D5391 TOMM70 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TOMM22 TOMM70 16689936 23283984 24234451 25348397 27898060 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct,OmniPath
TRAF6 TOMM70 25348397 N/A physical interaction ComPPI
MCM2 TOMM70 25348397 N/A physical interaction ComPPI
PPP1R15A TOMM70 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
DHX9 TOMM70 25348397 N/A physical interaction ComPPI
HSP90AA1 TOMM70 12526792 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NTRK1 TOMM70 25348397 N/A physical interaction ComPPI
IRF3 TOMM70 25348397 N/A physical interaction ComPPI
PTPN1 TOMM70 25348397 N/A physical interaction ComPPI
HSPA1A TOMM70 12526792 14525934 23414517 24234451 25348397 physical association experimental interaction detection,two hybrid fragment pooling approach,in vivo ComPPI,HPRD,IntAct
HSPA1B TOMM70 25348397 N/A two hybrid fragment pooling approach,in vivo ComPPI
LAMTOR3 TOMM70 25348397 N/A physical interaction ComPPI
PTPN5 TOMM70 25348397 N/A physical interaction ComPPI
IRAK1 TOMM70 25348397 N/A physical interaction ComPPI
RAB1A TOMM70 25348397 N/A physical interaction ComPPI
ABCC2 TOMM70 25348397 N/A physical interaction ComPPI
SNAPIN TOMM70 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ADRB2 TOMM70 25348397 N/A physical interaction ComPPI
EGFR TOMM70 25348397 N/A physical interaction ComPPI
HSPB1 TOMM70 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
PRKN TOMM70 23068103 23503661 24149440 24244333 25348397 25591737 27898060 N/A physical interaction ComPPI,OmniPath
TBK1 TOMM70 25348397 N/A physical interaction ComPPI
TRADD TOMM70 25348397 N/A physical interaction ComPPI
PTBP1 TOMM70 25348397 N/A physical interaction ComPPI
TOMM20 TOMM70 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HNRNPM TOMM70 25348397 N/A physical interaction ComPPI
TOMM7 TOMM70 25348397 N/A physical interaction ComPPI
TIMM50 TOMM70 25348397 N/A physical interaction ComPPI
TOMM40 TOMM70 1327874 17978093 21825073 25348397 27898060 8119994 9217162 9774667 N/A physical interaction ComPPI,OmniPath
AIFM1 TOMM70 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MAVS TOMM70 25348397 N/A physical interaction ComPPI
COX4I1 TOMM70 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PLGRKT TOMM70 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 TOMM70 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KSR1 TOMM70 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
TOMM70 RNF185 25348397 N/A physical interaction ComPPI
TOMM70 SDHA 25348397 N/A physical interaction ComPPI
TOMM70 SFXN1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TOMM70 SFXN2 25348397 N/A physical interaction ComPPI
TOMM70 CPS1 25348397 N/A physical interaction ComPPI
TOMM70 STING1 25348397 N/A physical interaction ComPPI
TOMM70 HSP90AA2P 25348397 N/A physical interaction ComPPI
TOMM70 STAU1 25348397 N/A physical interaction ComPPI
TOMM70 UNK 25348397 N/A physical interaction ComPPI
TOMM70 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TOMM70 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TOMM70 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TOMM70 SCO1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PINK1 TOMM70 25348397 N/A physical interaction ComPPI
TOMM70 AHNAK2 24234451 30021884 physical association cross-linking study IntAct
NBAS TOMM70 24234451 30021884 physical association cross-linking study IntAct
TOMM70 MSL1 24234451 30021884 physical association cross-linking study IntAct
TTC28 TOMM70 24234451 30021884 physical association cross-linking study IntAct
AOPEP TOMM70 24234451 30021884 physical association cross-linking study IntAct
RPL13A TOMM70 24234451 30021884 physical association cross-linking study IntAct
H2BC9 TOMM70 24234451 30021884 physical association cross-linking study IntAct
DDX27 TOMM70 24234451 30021884 physical association cross-linking study IntAct
TOMM70 TPK1 21215441 22419819 27898060 N/A N/A OmniPath
TOMM70 MAVS 20628368 27898060 N/A N/A OmniPath
IRAK1 TOMM70 21903422 27898060 N/A N/A OmniPath

Visualization










  Return