Gene Information gene info

GENE:TSG101

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TSG101
FullNmae tumor susceptibility 101
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15971
EnsembleID ENSG00000074319
Uniprot Q99816

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TSG101 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSG101 lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSG101 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSG101 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TSG101 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TSG101 GO:0000122,GO:0000813,GO:0000813,GO:0000813,GO:0000813,GO:0000813,GO:0001558,GO:0003677,GO:0003714,GO:0005515,GO:0005730,GO:0005737,GO:0005737,GO:0005768,GO:0005769,GO:0005770,GO:0005771,GO:0005815,GO:0005829,GO:0005886,GO:0006858,GO:0007049,GO:0007175,GO:0008285,GO:0008333,GO:0010008,GO:0010008,GO:0016236,GO:0019076,GO:0030216,GO:0031625,GO:0031901,GO:0031902,GO:0036211,GO:0036258,GO:0036258,GO:0039702,GO:0042059,GO:0042803,GO:0043130,GO:0043130,GO:0043130,GO:0043162,GO:0043162,GO:0043162,GO:0043328,GO:0043405,GO:0044877,GO:0046755,GO:0046755,GO:0046790,GO:0048306,GO:0051301,GO:0051726,GO:0070062,GO:0070062,GO:0090148,GO:0090543,GO:0097352,GO:1903543,GO:1903551,GO:1903774,GO:1990182,GO:2000397

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TSG101 hsa:7251 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)
TSG101 hsa:7251 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TSG101 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TSG101 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TSG101 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TSG101 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TSG101 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TSG101 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TSG101 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MAZ TSG101 21556761 trascriptional regulation,stimulation inferred by curator TFlink
TTF2 TSG101 21556761 trascriptional regulation,stimulation inferred by curator TFlink
FOXE1 TSG101 21556761 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000042E1F TSG101 21751348 rna interference,inhibition experimental interaction detection miRSponge
URS00002C0FCB TSG101 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 TSG101 20371350 21572407 22473208 23592263 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000CBE63 TSG101 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000042E1F TSG101 21572407 21751348 22473208 23592263 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS00002075FA TSG101 21572407 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC TSG101 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 TSG101 21572407 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 TSG101 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 TSG101 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE TSG101 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 TSG101 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 TSG101 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 TSG101 21572407 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 TSG101 21572407 22473208 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 TSG101 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 TSG101 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GMCL1 TSG101 12927808 14525934 25348397 27898060 N/A two hybrid,two hybrid ComPPI,HPRD,OmniPath
RBPMS TSG101 25348397 N/A barcode fusion genetics two hybrid ComPPI
VPS37C TSG101 14525934 15509564 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
KRT18 TSG101 19549727 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDX6 TSG101 25348397 N/A physical interaction ComPPI
UBE2I TSG101 25348397 N/A physical interaction ComPPI
ORC1 TSG101 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
SNW1 TSG101 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDC5L TSG101 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
FAM110A TSG101 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DAXX TSG101 15033475 24234451 25348397 physical association two hybrid,coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
PPP1R13B TSG101 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FTL TSG101 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
SH3KBP1 TSG101 25348397 N/A physical interaction ComPPI
ZFYVE9 TSG101 25348397 N/A physical interaction ComPPI
VASP TSG101 25348397 N/A physical interaction ComPPI
CDKN1A TSG101 11943869 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
VCP TSG101 25348397 N/A physical interaction ComPPI
ROCK1 TSG101 14525934 17853893 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
TNIP1 TSG101 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT31 TSG101 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CRK TSG101 25348397 N/A physical interaction ComPPI
CPSF7 TSG101 25348397 N/A physical interaction ComPPI
LARP1 TSG101 25348397 N/A physical interaction ComPPI
VPS37B TSG101 14525934 15218037 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
CBY1 TSG101 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NF2 TSG101 25348397 N/A physical interaction ComPPI
CBL TSG101 25348397 N/A physical interaction ComPPI
CD2AP TSG101 17853893 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF111 TSG101 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GRB2 TSG101 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN TSG101 25348397 N/A physical interaction ComPPI
AR TSG101 10508170 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
EP300 TSG101 10440698 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
NONO TSG101 25348397 N/A physical interaction ComPPI
SFPQ TSG101 25348397 N/A physical interaction ComPPI
THRB TSG101 25348397 N/A physical interaction ComPPI
ACTN4 TSG101 25348397 N/A physical interaction ComPPI
RAB7A TSG101 25348397 N/A physical interaction ComPPI
HGS TSG101 12802020 12900394 12900395 14525934 16189514 17182674 17229889 17320394 19542561 21070952 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,x-ray crystallography,physical interaction,two hybrid pooling approach,in vivo ComPPI,HPRD,IntAct,OmniPath
TOM1L1 TSG101 14525934 15611048 18367816 24234451 25348397 27898060 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct,OmniPath
UBB TSG101 15053872 24234451 25348397 N/A x-ray crystallography,in vitro ComPPI,IntAct
UBC TSG101 11916981 12006492 15053872 19542561 24234451 25348397 26456826 27898060 N/A pull down,physical interaction,in vitro ComPPI,IntAct,OmniPath
RPS27A TSG101 25348397 N/A in vitro ComPPI
UBA52 TSG101 11916981 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NTRK1 TSG101 25348397 N/A physical interaction ComPPI
ENO1 TSG101 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
YBX1 TSG101 25348397 N/A physical interaction ComPPI
BAG6 TSG101 25348397 N/A physical interaction ComPPI
POLD2 TSG101 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
EPHA2 TSG101 25348397 N/A physical interaction ComPPI
PABPC4 TSG101 25348397 N/A physical interaction ComPPI
NELFCD TSG101 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
STAM2 TSG101 25348397 N/A physical interaction ComPPI
IQGAP1 TSG101 14525934 17853893 24234451 25348397 physical association affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PDLIM7 TSG101 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PABPC1 TSG101 25348397 N/A physical interaction ComPPI
DAPK3 TSG101 25348397 N/A physical interaction ComPPI
NDRG1 TSG101 25348397 N/A physical interaction ComPPI
EWSR1 TSG101 25348397 N/A physical interaction ComPPI
RAD18 TSG101 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAB5A TSG101 25348397 N/A physical interaction ComPPI
XPO1 TSG101 25348397 N/A physical interaction ComPPI
AATF TSG101 14525934 14761944 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
RRM2 TSG101 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TRIM23 TSG101 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 TSG101 11172000 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ITSN1 TSG101 25348397 N/A physical interaction ComPPI
CEP55 TSG101 14525934 16189514 17853893 19549727 20176808 24234451 25348397 25416956 27107012 colocalization,association,physical association affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,fluorescence microscopy,in vitro,gal4 vp16 complementation,two hybrid prey pooling approach,split luciferase complementation,validated two hybrid,barcode fusion genetics two hybrid,two hybrid ComPPI,HPRD,IntAct
EHHADH TSG101 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
ADRB2 TSG101 25348397 N/A physical interaction ComPPI
EGFR TSG101 25348397 N/A physical interaction ComPPI
BCR TSG101 16778200 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PALLD TSG101 25348397 N/A physical interaction ComPPI
WDR12 TSG101 25348397 N/A physical interaction ComPPI
TAX1BP1 TSG101 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TSG101 DMAP1 10888872 14525934 15033475 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
TSG101 GGA3 14525934 15039775 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
TSG101 GGA1 14525934 15143060 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
TSG101 PDCD6IP 14505570 14525934 17350572 24234451 25348397 physical association two hybrid,experimental interaction detection,surface plasmon resonance,physical interaction,in vitro,surface plasmon resonance array,two hybrid ComPPI,HPRD,IntAct
TSG101 KRT15 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TSG101 PPFIBP2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TSG101 DNMT1 10888872 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
TSG101 SCAMP3 14525934 19158374 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TSG101 NR3C1 10508170 14525934 15657031 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
TSG101 HCK 12029088 14525934 24234451 25348397 physical association experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
TSG101 TP53 11172000 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TSG101 RNF41 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSG101 DZIP3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSG101 GJA1 25348397 N/A physical interaction ComPPI
TSG101 BIRC2 25348397 N/A physical interaction ComPPI
TSG101 ATXN2 25348397 N/A physical interaction ComPPI
TSG101 CAPRIN1 25348397 N/A physical interaction ComPPI
TSG101 FASN 25348397 N/A physical interaction ComPPI
TSG101 HNRNPUL1 19549727 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TSG101 EIF4B 25348397 N/A physical interaction ComPPI
TSG101 NFKB2 25348397 N/A physical interaction ComPPI
TSG101 NUFIP2 25348397 N/A physical interaction ComPPI
TSG101 DLAT 25348397 N/A physical interaction ComPPI
TSG101 UPF1 25348397 N/A physical interaction ComPPI
TSG101 SEC23IP 25348397 N/A physical interaction ComPPI
TSG101 SEC16A 25348397 N/A physical interaction ComPPI
TSG101 SEC24B 25348397 N/A physical interaction ComPPI
TSG101 TNKS1BP1 25348397 N/A physical interaction ComPPI
TSG101 TFG 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSG101 ALG2 25348397 N/A physical interaction ComPPI
TSG101 TOM1 25348397 N/A physical interaction ComPPI
TSG101 AKAP9 18643869 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TSG101 NEDD4 25348397 N/A physical interaction ComPPI
TSG101 UBAP1 25348397 N/A physical interaction ComPPI
TSG101 RAB11FIP4 25348397 N/A physical interaction ComPPI
TSG101 RAB11FIP3 25348397 N/A physical interaction ComPPI
TSG101 LITAF 16118794 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSG101 KCNN4 25348397 N/A physical interaction ComPPI
TSG101 KIFC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TSG101 KRT13 25348397 N/A physical interaction ComPPI
TSG101 USHBP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TSG101 SYCE1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TSG101 HAUS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TSG101 FAM9B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TSG101 MOV10 25348397 N/A physical interaction ComPPI
TSG101 NXF1 25348397 N/A physical interaction ComPPI
TSG101 DNAJB1 25348397 N/A physical interaction ComPPI
TSG101 DPH2 25348397 N/A physical interaction ComPPI
TSG101 DPYSL2 25348397 N/A physical interaction ComPPI
TSG101 HIP1R 25348397 N/A physical interaction ComPPI
TSG101 SMCHD1 25348397 N/A physical interaction ComPPI
TSG101 TRIM25 25348397 N/A physical interaction ComPPI
TSG101 WARS1 25348397 N/A physical interaction ComPPI
TSG101 KLK5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSG101 KLK6 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSG101 RASL10B 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSG101 SCGB3A1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSG101 STK11 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TSG101 BCAR1 25348397 N/A physical interaction ComPPI
TSG101 CHMP5 25348397 N/A physical interaction ComPPI
TSG101 PDCD6 18256029 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
TSG101 ATP5PB 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 FDPS 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 SMARCC2 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 SH2D3A 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 ABCB6 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 DCTN2 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 IMMT 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 COPS6 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 SCRIB 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 LAP3 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 VRK3 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 NDUFA13 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 NT5DC2 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TSG101 ZWINT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 TFIP11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 LCN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 TRIM54 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 AJUBA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 KRT16 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TSG101 BAG4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRAIP TSG101 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
WDR5 TSG101 25348397 N/A physical interaction ComPPI
TFF1 TSG101 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NR3C2 TSG101 22798426 23548632 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B6C05 TSG101 27087310 direct interaction,inhibition N/A NPInter

Visualization