Gene Information gene info

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GENE：TUBA3C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBA3C
FullNmae tubulin alpha 3c
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12408
EnsembleID ENSG00000198033
Uniprot P0DPH7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBA3C autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBA3C GO:0000226,GO:0000278,GO:0005200,GO:0005525,GO:0005634,GO:0005737,GO:0005874,GO:0015630,GO:0016787,GO:0036064,GO:0036098,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBA3C hsa:7278 path:hsa04145 Phagosome - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa04210 Apoptosis - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa04530 Tight junction - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa04540 Gap junction - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05020 Prion disease - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBA3C hsa:7278 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TUBA3C IL7R 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
TUBA3C NMI 16189514 23180781 physical association pull down InnateDB
TUBA3C TSGA10 20797700 23180781 physical association affinity chromatography technology InnateDB
TUBA3C UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
FOS TUBA3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TUBA3C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
NMI TUBA3C 14525934 16189514 24234451 25348397 physical association pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
ZNF408 TUBA3C 25348397 N/A physical interaction ComPPI
UBL4A TUBA3C 25348397 N/A physical interaction ComPPI
TRAF6 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
YWHAG TUBA3C 25348397 N/A physical interaction ComPPI
MCM2 TUBA3C 25348397 N/A physical interaction ComPPI
PTPN9 TUBA3C 25348397 N/A physical interaction ComPPI
SPAG5 TUBA3C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KATNAL1 TUBA3C 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
KATNBL1 TUBA3C 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
H4C1 TUBA3C 25348397 N/A physical interaction ComPPI
SOCS1 TUBA3C 19327355 24234451 25348397 27898060 colocalization fluorescence microscopy ComPPI,IntAct,OmniPath
REL TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PPP4C TUBA3C 25348397 N/A physical interaction ComPPI
CD81 TUBA3C 25348397 N/A physical interaction ComPPI
FEZ1 TUBA3C 25348397 N/A physical interaction ComPPI
CUL3 TUBA3C 25348397 N/A physical interaction ComPPI
YWHAB TUBA3C 25348397 N/A physical interaction ComPPI
YWHAZ TUBA3C 25348397 N/A physical interaction ComPPI
UBC TUBA3C 25348397 N/A physical interaction ComPPI
IKBKB TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1A TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NFKBIA TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DCTN1 TUBA3C 17563362 24234451 25348397 N/A surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct
STXBP3 TUBA3C 25348397 N/A physical interaction ComPPI
HMGB1 TUBA3C 25348397 N/A physical interaction ComPPI
RELA TUBA3C 25348397 N/A tandem affinity purification ComPPI
BCHE TUBA3C 25348397 N/A physical interaction ComPPI
YWHAQ TUBA3C 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
TRAF1 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRAF2 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NFKBIB TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ARRB1 TUBA3C 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARRB2 TUBA3C 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1A TUBA3C 25348397 N/A physical interaction ComPPI
VHL TUBA3C 25348397 N/A physical interaction ComPPI
MAP1LC3A TUBA3C 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B TUBA3C 25348397 N/A physical interaction ComPPI
CHUK TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PTEN TUBA3C 25348397 N/A physical interaction ComPPI
STK4 TUBA3C 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RIPK1 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK3 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1B TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K8 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K14 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ZNF24 TUBA3C 25348397 N/A physical interaction ComPPI
USH1C TUBA3C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
FYN TUBA3C 11826099 14525934 25348397 8566014 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MAP3K7 TUBA3C 25348397 N/A tandem affinity purification ComPPI
TAB2 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NFKB2 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TBK1 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ARL4D TUBA3C 25348397 N/A physical interaction ComPPI
DYNLT1 TUBA3C 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAP3K3 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PML TUBA3C 25348397 N/A physical interaction ComPPI
TANK TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
DYRK2 TUBA3C 25348397 N/A physical interaction ComPPI
KATNA1 TUBA3C 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
KATNB1 TUBA3C 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
IKBKE TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CST7 TUBA3C 25348397 N/A physical interaction ComPPI
DCAF12 TUBA3C 25348397 N/A physical interaction ComPPI
CHRM3 TUBA3C 25348397 N/A physical interaction ComPPI
MTM1 TUBA3C 25348397 N/A physical interaction ComPPI
NFKBIE TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RELB TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ATP6V0D1 TUBA3C 25348397 N/A physical interaction ComPPI
TXNDC9 TUBA3C 25348397 N/A physical interaction ComPPI
UTP3 TUBA3C 25348397 N/A physical interaction ComPPI
SH2D4A TUBA3C 25348397 N/A physical interaction ComPPI
CEP70 TUBA3C 25348397 N/A physical interaction ComPPI
TSGA10 TUBA3C 25348397 N/A physical interaction ComPPI
ROGDI TUBA3C 25348397 N/A physical interaction ComPPI
FBL TUBA3C 25348397 N/A physical interaction ComPPI
CCT2 TUBA3C 25348397 N/A physical interaction ComPPI
TUBA1C TUBA3C 25348397 N/A physical interaction ComPPI
LRRCC1 TUBA3C 25348397 N/A physical interaction ComPPI
HJURP TUBA3C 25348397 N/A physical interaction ComPPI
LGALS7 TUBA3C 25348397 N/A physical interaction ComPPI
MAP3K1 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CCT3 TUBA3C 25348397 N/A physical interaction ComPPI
FAM13C TUBA3C 25348397 N/A physical interaction ComPPI
TUBA3C CFAP77 25348397 N/A physical interaction ComPPI
TUBA3C GPN2 25348397 N/A physical interaction ComPPI
TUBA3C P2RY8 25348397 N/A physical interaction ComPPI
TUBA3C RETREG3 25348397 N/A physical interaction ComPPI
TUBA3C OLFM1 25348397 N/A physical interaction ComPPI
TUBA3C TCP11L2 25348397 N/A physical interaction ComPPI
TUBA3C MFSD4B 25348397 N/A physical interaction ComPPI
TUBA3C ZNF384 25348397 N/A physical interaction ComPPI
TUBA3C HSFY1 25348397 N/A physical interaction ComPPI
TUBA3C ARHGAP36 25348397 N/A physical interaction ComPPI
TUBA3C ZNF416 25348397 N/A physical interaction ComPPI
TUBA3C ZNF610 25348397 N/A physical interaction ComPPI
TUBA3C FAM71D 25348397 N/A physical interaction ComPPI
TUBA3C NEK4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TUBA3C G3BP1 25348397 N/A physical interaction ComPPI
TUBA3C CLIP1 25348397 N/A physical interaction,surface plasmon resonance array ComPPI
TUBA3C IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBA3C TAB1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBA3C KATNAL2 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBA3C NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
TTC5 TUBA3C 25348397 N/A physical interaction ComPPI
TUBA3C MYC 14525934 7651436 N/A experimental interaction detection HPRD
TUBA3C TUBG1 11082048 14525934 N/A experimental interaction detection HPRD
TUBA3C DYNLL1 14525934 14760703 N/A experimental interaction detection HPRD
TUBA3C SIAH1 11146551 14525934 N/A two hybrid HPRD
GRM7 TUBA3C 11953448 14525934 N/A experimental interaction detection HPRD
ESR2 TUBA3C 21951318 24234451 association anti tag coimmunoprecipitation IntAct
TPT1 TUBA3C 24234451 27607350 association anti bait coimmunoprecipitation IntAct
IL7R TUBA3C 20167604 27898060 N/A N/A OmniPath
NUMA1 TUBA3C 11956313 27898060 stimulant N/A OmniPath
TTL TUBA3C 22020298 27898060 inhibition N/A OmniPath

Visualization










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