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GENE：TUBA8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBA8
FullNmae tubulin alpha 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12410
EnsembleID ENSG00000183785
Uniprot Q9NY65

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBA8 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBA8 GO:0000226,GO:0000278,GO:0001669,GO:0005200,GO:0005515,GO:0005525,GO:0005737,GO:0005874,GO:0007286,GO:0015630,GO:0016787,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBA8 hsa:51807 path:hsa04145 Phagosome - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa04210 Apoptosis - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa04530 Tight junction - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa04540 Gap junction - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05020 Prion disease - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBA8 hsa:51807 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TUBA8 IL7R 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
TUBA8 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 TUBA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TUBA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUBA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TUBA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TUBA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TUBA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 TUBA8 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000521626 TUBA8 17612493 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
RPL37A TUBA8 25348397 N/A physical interaction ComPPI
UBL4A TUBA8 25348397 N/A physical interaction ComPPI
NOL12 TUBA8 25348397 N/A physical interaction ComPPI
SLC38A1 TUBA8 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
CD81 TUBA8 25348397 N/A physical interaction ComPPI
SHC1 TUBA8 25348397 N/A physical interaction ComPPI
SIAH1 TUBA8 11146551 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
MYC TUBA8 14525934 25348397 7651436 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PXN TUBA8 25348397 N/A two hybrid,in vivo ComPPI
CFTR TUBA8 25348397 N/A physical interaction ComPPI
PPP2CA TUBA8 25348397 N/A physical interaction ComPPI
RPLP0 TUBA8 25348397 N/A physical interaction ComPPI
ARRB2 TUBA8 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TCP1 TUBA8 14525934 25348397 9885248 N/A experimental interaction detection,in vivo ComPPI,HPRD
TUBA8 MEPCE 25348397 N/A physical interaction ComPPI
TUBA8 IGSF8 25348397 N/A physical interaction ComPPI
TUBA8 HDAC6 25348397 N/A physical interaction ComPPI
TUBA8 LGR4 25348397 N/A physical interaction ComPPI
TUBA8 TP53 25348397 N/A physical interaction ComPPI
TUBA8 UBAC2 25348397 N/A physical interaction ComPPI
TUBA8 ERLIN2 25348397 N/A physical interaction ComPPI
TUBA8 H1-1 25348397 N/A physical interaction ComPPI
TUBA8 RPL13 25348397 N/A physical interaction ComPPI
TUBA8 ZC3H8 25348397 N/A physical interaction ComPPI
TUBA8 TRMT10B 25348397 N/A physical interaction ComPPI
TUBA8 RPLP0P6 25348397 N/A physical interaction ComPPI
TUBA8 ZNF317 25348397 N/A physical interaction ComPPI
TUBA8 MKS1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TUBA8 GAN 25348397 N/A physical interaction ComPPI
TUBA8 DPF3 25348397 N/A physical interaction ComPPI
TUBA8 MACROH2A2 25348397 N/A physical interaction ComPPI
TUBA8 MAK16 25348397 N/A physical interaction ComPPI
TUBA8 CDX1 25348397 N/A physical interaction ComPPI
TUBA8 H1-6 25348397 N/A physical interaction ComPPI
TUBA8 IGHMBP2 25348397 N/A physical interaction ComPPI
TUBA8 CYLD 25348397 N/A physical interaction ComPPI
TUBA8 CCND2 25348397 N/A physical interaction ComPPI
TUBA8 TARDBP 25348397 N/A physical interaction ComPPI
TUBA8 CLIP1 25348397 N/A physical interaction,surface plasmon resonance array ComPPI
TUBA8 IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBA8 HTR7 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUBA8 TCP11L2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBM4B TUBA8 25348397 N/A physical interaction ComPPI
TUBA8 GRM7 11953448 14525934 N/A experimental interaction detection HPRD
MKI67 TUBA8 24234451 26949251 association anti tag coimmunoprecipitation IntAct
TPT1 TUBA8 24234451 27607350 association anti bait coimmunoprecipitation IntAct
NUMA1 TUBA8 11956313 27898060 stimulant N/A OmniPath
TTL TUBA8 22020298 27898060 inhibition N/A OmniPath

Visualization










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