Gene Information gene info

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GENE：TUBB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBB1
FullNmae tubulin beta 1 class VI
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16257
EnsembleID ENSG00000101162
Uniprot Q9H4B7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBB1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBB1 GO:0000226,GO:0000278,GO:0003924,GO:0005200,GO:0005525,GO:0005737,GO:0005737,GO:0005874,GO:0015630,GO:0030220,GO:0030878,GO:0045171,GO:0046785,GO:0046872,GO:0051225,GO:0070062,GO:0070327,GO:0070527,GO:0072686

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBB1 hsa:81027 path:hsa04145 Phagosome - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa04540 Gap junction - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05020 Prion disease - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBB1 hsa:81027 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R TUBB1 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TUBB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 TUBB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TUBB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TUBB1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TUBB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TUBB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000345DEB TUBB1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 TUBB1 12840015 20467437 24234451 25348397 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CUL5 TUBB1 25348397 N/A physical interaction ComPPI
GABARAPL2 TUBB1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ALPI TUBB1 25348397 N/A physical interaction ComPPI
MAP1LC3B TUBB1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KATNAL1 TUBB1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
JUN TUBB1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 TUBB1 25348397 N/A physical interaction ComPPI
CELA1 TUBB1 25348397 N/A physical interaction ComPPI
PRSS2 TUBB1 25348397 N/A physical interaction ComPPI
SERPINC1 TUBB1 25348397 N/A physical interaction ComPPI
CUL3 TUBB1 25348397 N/A physical interaction ComPPI
YWHAZ TUBB1 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
TUBG1 TUBB1 25348397 N/A physical interaction ComPPI
TUBA1B TUBB1 25348397 N/A physical interaction ComPPI
PARP1 TUBB1 25348397 N/A physical interaction ComPPI
SSBP1 TUBB1 25348397 N/A physical interaction ComPPI
PRG2 TUBB1 25348397 N/A physical interaction ComPPI
CFTR TUBB1 25348397 N/A physical interaction ComPPI
GABRG2 TUBB1 25348397 N/A physical interaction ComPPI
RAPGEF5 TUBB1 25348397 N/A physical interaction ComPPI
CUL2 TUBB1 25348397 N/A physical interaction ComPPI
CUL4B TUBB1 25348397 N/A physical interaction ComPPI
MDM2 TUBB1 17373842 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL1 TUBB1 25348397 N/A physical interaction ComPPI
CUL4A TUBB1 25348397 N/A physical interaction ComPPI
JAK3 TUBB1 25348397 N/A physical interaction ComPPI
MIER1 TUBB1 25348397 N/A physical interaction ComPPI
CTDSP1 TUBB1 25348397 N/A physical interaction ComPPI
GABARAP TUBB1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RASSF1 TUBB1 25348397 N/A imaging technique ComPPI
MAP1LC3A TUBB1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
STK4 TUBB1 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
COPS6 TUBB1 25348397 N/A physical interaction ComPPI
PSMD2 TUBB1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HIF1AN TUBB1 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
USH1C TUBB1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRKN TUBB1 25348397 N/A physical interaction ComPPI
CAND1 TUBB1 25348397 N/A physical interaction ComPPI
ZMYM2 TUBB1 25348397 N/A physical interaction ComPPI
CDC37 TUBB1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NFKB1 TUBB1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
SNCA TUBB1 25348397 N/A physical interaction ComPPI
ADAMTS4 TUBB1 25348397 N/A physical interaction ComPPI
NOP56 TUBB1 25348397 N/A physical interaction ComPPI
CRHBP TUBB1 25348397 N/A physical interaction ComPPI
ESR1 TUBB1 25348397 N/A physical interaction ComPPI
OTC TUBB1 25348397 N/A physical interaction ComPPI
KATNA1 TUBB1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
KATNB1 TUBB1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
PRKAB1 TUBB1 25348397 N/A physical interaction ComPPI
IL17RA TUBB1 25348397 N/A physical interaction ComPPI
PLA2G10 TUBB1 25348397 N/A physical interaction ComPPI
TUBB1 TTK 14525934 15304323 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TUBB1 FBL 25348397 N/A physical interaction ComPPI
TUBB1 MYSM1 25348397 N/A physical interaction ComPPI
TUBB1 FBXO25 25348397 N/A physical interaction ComPPI
TUBB1 SLC6A3 25348397 N/A physical interaction ComPPI
TUBB1 ACAT1 25348397 N/A physical interaction ComPPI
TUBB1 HADHB 25348397 N/A physical interaction ComPPI
TUBB1 SFRP4 25348397 N/A physical interaction ComPPI
TUBB1 PRSS50 25348397 N/A physical interaction ComPPI
TUBB1 TUBB2B 25348397 N/A physical interaction ComPPI
TUBB1 CBWD2 25348397 N/A physical interaction ComPPI
TUBB1 ALDH3B1 25348397 N/A physical interaction ComPPI
TUBB1 ASTL 25348397 N/A physical interaction ComPPI
TUBB1 CLEC5A 25348397 N/A physical interaction ComPPI
TUBB1 MC1R 25348397 N/A physical interaction ComPPI
TUBB1 TUBB3 25348397 N/A physical interaction ComPPI
TUBB1 TSPYL6 25348397 N/A physical interaction ComPPI
TUBB1 MUC20 25348397 N/A physical interaction ComPPI
TUBB1 DOCK5 25348397 N/A physical interaction ComPPI
TUBB1 WNT7A 25348397 N/A physical interaction ComPPI
TUBB1 GLMP 25348397 N/A physical interaction ComPPI
TUBB1 ENPP7 25348397 N/A physical interaction ComPPI
TUBB1 SIRT6 25348397 N/A physical interaction ComPPI
TUBB1 PSG1 25348397 N/A physical interaction ComPPI
TUBB1 PSG8 25348397 N/A physical interaction ComPPI
TUBB1 TOR1AIP2 25348397 N/A physical interaction ComPPI
TUBB1 TOR1AIP2 25348397 N/A physical interaction ComPPI
TUBB1 LIPG 25348397 N/A physical interaction ComPPI
TUBB1 NPAS1 25348397 N/A physical interaction ComPPI
TUBB1 TCTN1 25348397 N/A physical interaction ComPPI
TUBB1 RPGR 25348397 N/A physical interaction ComPPI
TUBB1 OLFM2 25348397 N/A physical interaction ComPPI
TUBB1 KLHL33 25348397 N/A physical interaction ComPPI
TUBB1 ACAD9 25348397 N/A physical interaction ComPPI
TUBB1 MFSD11 25348397 N/A physical interaction ComPPI
TUBB1 DNLZ 25348397 N/A physical interaction ComPPI
TUBB1 NEK4 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TUBB1 NPHP4 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TUBB1 AAR2 25348397 N/A physical interaction ComPPI
TUBB1 CLIP1 25348397 N/A physical interaction,surface plasmon resonance array ComPPI
TUBB1 DYNC1I1 16616141 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TUBB1 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB1 HTR7 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUBB1 LRRK2 24234451 24275654 25348397 physical association two hybrid ComPPI,IntAct
TUBB1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TUBB1 KATNAL2 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
IL7R TUBB1 20167604 27898060 N/A N/A OmniPath

Visualization










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