Gene Information gene info

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GENE：TUBB2B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBB2B
FullNmae tubulin beta 2B class IIb
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30829
EnsembleID ENSG00000137285
Uniprot Q9BVA1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBB2B autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBB2B GO:0000226,GO:0000278,GO:0001764,GO:0003924,GO:0005200,GO:0005515,GO:0005525,GO:0005634,GO:0005737,GO:0005874,GO:0005874,GO:0007017,GO:0015630,GO:0021987,GO:0045171,GO:0046872,GO:0046982,GO:0050804,GO:0072686,GO:0098685,GO:1902669,GO:1990403

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBB2B hsa:347733 path:hsa04145 Phagosome - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa04540 Gap junction - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05020 Prion disease - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBB2B hsa:347733 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CACNA1A TUBB2B 21078624 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR TUBB2B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 TUBB2B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TUBB2B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TUBB2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D TUBB2B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 TUBB2B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 TUBB2B 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DCX TUBB2B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDKN1A TUBB2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRAF6 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
VCP TUBB2B 25348397 N/A physical interaction ComPPI
MCM5 TUBB2B 25348397 N/A physical interaction ComPPI
TUBA3E TUBB2B 25348397 N/A physical interaction ComPPI
KEAP1 TUBB2B 25348397 N/A physical interaction ComPPI
MCM2 TUBB2B 25348397 N/A physical interaction ComPPI
CD81 TUBB2B 25348397 N/A physical interaction ComPPI
SHC1 TUBB2B 25348397 N/A physical interaction ComPPI
PPP1R15A TUBB2B 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
JUN TUBB2B 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
INPPL1 TUBB2B 25348397 N/A physical interaction ComPPI
CUL3 TUBB2B 25348397 N/A physical interaction ComPPI
TUBA1B TUBB2B 25348397 N/A physical interaction ComPPI
HSP90AA1 TUBB2B 21360678 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 TUBB2B 25348397 N/A physical interaction ComPPI
IKBKB TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1A TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
LRP1 TUBB2B 25348397 N/A physical interaction ComPPI
TUBA4A TUBB2B 25348397 N/A physical interaction ComPPI
DUSP16 TUBB2B 24234451 25348397 28330616 association pull down ComPPI,IntAct
RGS2 TUBB2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDK TUBB2B 25348397 N/A physical interaction ComPPI
RELA TUBB2B 25348397 N/A tandem affinity purification ComPPI
TBCD TUBB2B 25348397 N/A physical interaction ComPPI
CACNA1A TUBB2B 21078624 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
TUBA1A TUBB2B 24234451 25348397 29568061 association pull down ComPPI,IntAct
YWHAE TUBB2B 25348397 N/A physical interaction ComPPI
CCT7 TUBB2B 25348397 N/A physical interaction ComPPI
HDAC6 TUBB2B 25348397 N/A physical interaction ComPPI
EPHA4 TUBB2B 25348397 N/A physical interaction ComPPI
RIPK2 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK3 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1B TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K14 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ITGA4 TUBB2B 25348397 N/A physical interaction ComPPI
HIF1AN TUBB2B 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP3K7 TUBB2B 25348397 N/A tandem affinity purification ComPPI
CUL7 TUBB2B 25348397 N/A physical interaction ComPPI
PEX14 TUBB2B 21525035 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TRIM25 TUBB2B 25348397 N/A physical interaction ComPPI
CENPU TUBB2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYO10 TUBB2B 21642953 24234451 25348397 N/A pull down ComPPI,IntAct
MAP3K3 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRAF3IP1 TUBB2B 20391533 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EML1 TUBB2B 25348397 N/A physical interaction ComPPI
CDC42SE2 TUBB2B 25348397 N/A physical interaction ComPPI
FAS TUBB2B 25348397 N/A physical interaction ComPPI
PPEF1 TUBB2B 24234451 25348397 28330616 association pull down ComPPI,IntAct
ARL2 TUBB2B 25348397 N/A physical interaction ComPPI
CEP250 TUBB2B 25348397 N/A physical interaction ComPPI
TUBB1 TUBB2B 25348397 N/A physical interaction ComPPI
CSNK2B TUBB2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NPHP4 TUBB2B 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TSEN2 TUBB2B 25348397 N/A physical interaction ComPPI
L3MBTL1 TUBB2B 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
RPGR TUBB2B 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CYLD TUBB2B 25348397 N/A physical interaction ComPPI
RPS15A TUBB2B 25348397 N/A physical interaction ComPPI
TUBB3 TUBB2B 25348397 N/A physical interaction ComPPI
POU5F1 TUBB2B 25348397 N/A physical interaction ComPPI
CCT2 TUBB2B 25348397 N/A physical interaction ComPPI
CCT6A TUBB2B 25348397 N/A physical interaction ComPPI
TUBA1C TUBB2B 25348397 N/A physical interaction ComPPI
RPS4X TUBB2B 25348397 N/A physical interaction ComPPI
C8ORF33 TUBB2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EML4 TUBB2B 25348397 N/A physical interaction ComPPI
FBXO6 TUBB2B 25348397 N/A physical interaction ComPPI
ZNF146 TUBB2B 25348397 N/A physical interaction ComPPI
MAP3K1 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MC1R TUBB2B 25348397 N/A physical interaction ComPPI
ATOH1 TUBB2B 25348397 N/A physical interaction ComPPI
FOS TUBB2B 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CCT3 TUBB2B 25348397 N/A physical interaction ComPPI
BID TUBB2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EML2 TUBB2B 25348397 N/A physical interaction ComPPI
RPL35 TUBB2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TAB1 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HSP90AA2P TUBB2B 25348397 N/A physical interaction ComPPI
GAN TUBB2B 25348397 N/A physical interaction ComPPI
RIPK4 TUBB2B 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB2B ANXA7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TUBB2B METTL22 25348397 N/A physical interaction ComPPI
TUBB2B ASB17 25348397 N/A physical interaction ComPPI
TUBB2B OBSL1 25348397 N/A physical interaction ComPPI
TUBB2B TUBB8 25348397 N/A physical interaction ComPPI
TUBB2B CCT6B 25348397 N/A physical interaction ComPPI
TUBB2B TCP11L1 25348397 N/A physical interaction ComPPI
TUBB2B CAPS 25348397 N/A physical interaction ComPPI
TUBB2B EML6 25348397 N/A physical interaction ComPPI
TUBB2B LAMP3 25348397 N/A physical interaction ComPPI
TUBB2B LRRK2 24234451 24275654 25348397 physical association two hybrid ComPPI,IntAct
TPSB2 TUBB2B 25348397 N/A physical interaction ComPPI
TTC5 TUBB2B 25348397 N/A physical interaction ComPPI
CACNA1A TUBB2B 21078624 27898060 N/A N/A OmniPath

Visualization










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