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GENE：TUBB4A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBB4A
FullNmae tubulin beta 4A class IVa
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20774
EnsembleID ENSG00000104833
Uniprot P04350

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBB4A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TUBB4A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TUBB4A autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBB4A GO:0000226,GO:0000278,GO:0003924,GO:0005200,GO:0005509,GO:0005515,GO:0005525,GO:0005634,GO:0005737,GO:0005829,GO:0005874,GO:0005874,GO:0005930,GO:0015630,GO:0031115,GO:0033269,GO:0043025,GO:0043209,GO:0045171,GO:0070062,GO:0072686

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBB4A hsa:10382 path:hsa04145 Phagosome - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa04540 Gap junction - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05020 Prion disease - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBB4A hsa:10382 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R TUBB4A 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 TUBB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TUBB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUBB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 TUBB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TUBB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TUBB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TUBB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002971AB TUBB4A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000009A9A2 TUBB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 TUBB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A TUBB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 TUBB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 TUBB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000A07C1 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001799A3 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000364FEF TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003B6B84 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000019D79B TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 TUBB4A 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 TUBB4A 25348397 N/A physical interaction ComPPI
CUL5 TUBB4A 25348397 N/A physical interaction ComPPI
TUBB TUBB4A 25348397 N/A physical interaction ComPPI
UBL4A TUBB4A 25348397 N/A physical interaction ComPPI
TRAF6 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MCM5 TUBB4A 25348397 N/A physical interaction ComPPI
YWHAG TUBB4A 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MRPL28 TUBB4A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBA3E TUBB4A 25348397 N/A physical interaction ComPPI
KEAP1 TUBB4A 25348397 N/A physical interaction ComPPI
MCM2 TUBB4A 25348397 N/A physical interaction ComPPI
KATNAL1 TUBB4A 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
KATNBL1 TUBB4A 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
NF2 TUBB4A 25348397 N/A physical interaction ComPPI
SP1 TUBB4A 25348397 N/A physical interaction ComPPI
REL TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
LYN TUBB4A 25348397 N/A physical interaction ComPPI
CD81 TUBB4A 25348397 N/A physical interaction ComPPI
KHDRBS1 TUBB4A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
JUN TUBB4A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL3 TUBB4A 25348397 N/A physical interaction ComPPI
IRS4 TUBB4A 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ILK TUBB4A 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAX1 TUBB4A 25348397 N/A physical interaction ComPPI
HSPA5 TUBB4A 25348397 N/A physical interaction ComPPI
IKBKB TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HEY1 TUBB4A 25348397 N/A physical interaction ComPPI
TNFRSF1A TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
LRP1 TUBB4A 25348397 N/A physical interaction ComPPI
NFKBIA TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFAIP1 TUBB4A 25348397 N/A physical interaction ComPPI
TUBA4A TUBB4A 25348397 N/A physical interaction ComPPI
BMPR2 TUBB4A 14525934 15188402 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RELA TUBB4A 25348397 N/A tandem affinity purification ComPPI
XPO1 TUBB4A 25348397 N/A physical interaction ComPPI
TRAF1 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRAF2 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ARRB2 TUBB4A 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL1 TUBB4A 25348397 N/A physical interaction ComPPI
EGFR TUBB4A 25348397 N/A physical interaction ComPPI
NR4A1 TUBB4A 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
GABARAP TUBB4A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HDAC6 TUBB4A 25348397 N/A physical interaction ComPPI
CHUK TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
STK11 TUBB4A 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RIPK1 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PSMD2 TUBB4A 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
RIPK3 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TNFRSF1B TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K8 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K14 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAP3K7 TUBB4A 25348397 N/A tandem affinity purification ComPPI
TAB2 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ARHGEF7 TUBB4A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
INSM1 TUBB4A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
NFKB1 TUBB4A 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
ANTXR1 TUBB4A 25348397 N/A physical interaction ComPPI
NFKB2 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PEX14 TUBB4A 21525035 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TRIM25 TUBB4A 25348397 N/A physical interaction ComPPI
TBK1 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRADD TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
IL12RB1 TUBB4A 25348397 N/A physical interaction ComPPI
TUBB4A POU5F1 25348397 N/A physical interaction ComPPI
TUBB4A AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4A TJP1 16944923 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TUBB4A SIRT7 25348397 N/A physical interaction ComPPI
TUBB4A FBXO25 25348397 N/A physical interaction ComPPI
TUBB4A CLN8 25348397 N/A physical interaction ComPPI
TUBB4A CAMKMT 25348397 N/A physical interaction ComPPI
TUBB4A FAM86B2 25348397 N/A physical interaction ComPPI
TUBB4A ETFBKMT 25348397 N/A physical interaction ComPPI
TUBB4A EEF1AKMT3 25348397 N/A physical interaction ComPPI
TUBB4A METTL22 25348397 N/A physical interaction ComPPI
TUBB4A METTL23 25348397 N/A physical interaction ComPPI
TUBB4A IGSF8 25348397 N/A physical interaction ComPPI
TUBB4A FBXO6 25348397 N/A physical interaction ComPPI
TUBB4A ASB4 25348397 N/A physical interaction ComPPI
TUBB4A DNAJA4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4A CEP250 25348397 N/A physical interaction ComPPI
TUBB4A TUBGCP2 25348397 N/A physical interaction ComPPI
TUBB4A KLK5 25348397 N/A physical interaction ComPPI
TUBB4A FAS 25348397 N/A physical interaction ComPPI
TUBB4A ISLR 25348397 N/A physical interaction ComPPI
TUBB4A TUBA1C 25348397 N/A physical interaction ComPPI
TUBB4A RPGR 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TUBB4A TINF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4A GAN 25348397 N/A physical interaction ComPPI
TUBB4A ALKBH3 25348397 N/A physical interaction ComPPI
TUBB4A GLMP 25348397 N/A physical interaction ComPPI
TUBB4A CDK13 25348397 N/A physical interaction ComPPI
TUBB4A ICAM1 25348397 N/A physical interaction ComPPI
TUBB4A TSPYL6 25348397 N/A physical interaction ComPPI
TUBB4A CCNJL 25348397 N/A physical interaction ComPPI
TUBB4A CYLD 25348397 N/A physical interaction ComPPI
TUBB4A TES 25348397 N/A physical interaction ComPPI
TUBB4A NFKBIE 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB4A IKBKE 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB4A IKBKG 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB4A MAP3K1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB4A MAP3K3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB4A RELB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB4A TAB1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB4A EEF1G 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A DDX39B 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A HEXD 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A TF 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A RILPL2 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A SPTSSA 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A SEL1L3 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A LAPTM4A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A PHIP 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A ROBO1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A CAMSAP3 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A LIG1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBB4A MAX 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
TUBB4A LRRK2 24234451 24275654 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct
TUBB4A RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4A ESR2 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
TUBB4A OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4A PPEF1 24234451 25348397 28330616 association pull down ComPPI,IntAct
TUBB4A PPM1D 24234451 25348397 28330616 association pull down ComPPI,IntAct
TUBB4A KATNA1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBB4A KATNAL2 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBB4A KATNB1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBB4A NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
TUBB4A SELENOF 24234451 25348397 29410696 physical association two hybrid ComPPI,IntAct
PTPN23 TUBB4A 24234451 25348397 28330616 association pull down ComPPI,IntAct
TPSB2 TUBB4A 25348397 N/A physical interaction ComPPI
TUBB4A STAU1 14525934 15121898 N/A experimental interaction detection HPRD
METTL3 TUBB4A 24234451 29507755 association anti tag coimmunoprecipitation IntAct
IL7R TUBB4A 20167604 27898060 N/A N/A OmniPath
NUMA1 TUBB4A 11956313 27898060 stimulant N/A OmniPath

Visualization










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