Gene Information gene info

  1. Home

GENE：TUBB4B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBB4B
FullNmae tubulin beta 4B class IVb
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20771
EnsembleID ENSG00000188229
Uniprot P68371

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBB4B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TUBB4B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TUBB4B autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBB4B GO:0000226,GO:0000278,GO:0003725,GO:0003924,GO:0005200,GO:0005515,GO:0005525,GO:0005576,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005874,GO:0005874,GO:0005879,GO:0015630,GO:0035578,GO:0042267,GO:0042288,GO:0045171,GO:0046872,GO:0051082,GO:0070062,GO:0072686,GO:1903561

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBB4B hsa:10383 path:hsa04145 Phagosome - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa04540 Gap junction - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05020 Prion disease - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBB4B hsa:10383 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YWHAE TUBB4B 20462248 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL7R TUBB4B 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
TLR2 TUBB4B 21827211 23180781 physical association anti tag coimmunoprecipitation InnateDB
EZH2 TUBB4B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 TUBB4B 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 TUBB4B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TUBB4B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TUBB4B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TUBB4B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TUBB4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 TUBB4B 23338554 rna interference,inhibition western blot miRSponge
URS0000065D58 TUBB4B 23338554 25416803 mrna cleavage,inhibition western blot TarBase
URS00002971AB TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031B6ED TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C11BC TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 TUBB4B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000105D19 TUBB4B 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 TUBB4B 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL5 TUBB4B 25348397 N/A physical interaction ComPPI
CDC5L TUBB4B 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB TUBB4B 25348397 N/A physical interaction ComPPI
EMD TUBB4B 25348397 N/A physical interaction ComPPI
UBL4A TUBB4B 25348397 N/A physical interaction ComPPI
VCP TUBB4B 25348397 N/A physical interaction ComPPI
MCM5 TUBB4B 25348397 N/A physical interaction ComPPI
GABARAPL2 TUBB4B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PCBD1 TUBB4B 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DCUN1D1 TUBB4B 25348397 N/A physical interaction ComPPI
RAD21 TUBB4B 25348397 N/A physical interaction ComPPI
KEAP1 TUBB4B 25348397 N/A physical interaction ComPPI
MCM2 TUBB4B 25348397 N/A physical interaction ComPPI
MAP1LC3B TUBB4B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CRK TUBB4B 25348397 N/A physical interaction ComPPI
KATNAL1 TUBB4B 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
KATNBL1 TUBB4B 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
RPL10A TUBB4B 25348397 N/A physical interaction ComPPI
CBL TUBB4B 25348397 N/A physical interaction ComPPI
BTK TUBB4B 21080425 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EZH2 TUBB4B 25348397 N/A physical interaction ComPPI
CD81 TUBB4B 25348397 N/A physical interaction ComPPI
SHC1 TUBB4B 25348397 N/A physical interaction ComPPI
GRB2 TUBB4B 12577067 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
JUN TUBB4B 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 TUBB4B 25348397 N/A physical interaction ComPPI
INPPL1 TUBB4B 25348397 N/A physical interaction ComPPI
CUL3 TUBB4B 25348397 N/A physical interaction ComPPI
YWHAB TUBB4B 25348397 N/A physical interaction ComPPI
CDKN2A TUBB4B 17955473 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TUBG1 TUBB4B 14525934 14594945 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TUBA1B TUBB4B 25348397 N/A physical interaction ComPPI
PFKP TUBB4B 25348397 N/A physical interaction ComPPI
HSP90AA1 TUBB4B 21360678 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 TUBB4B 25348397 N/A physical interaction ComPPI
SOCS7 TUBB4B 12052866 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CDH1 TUBB4B 25348397 N/A physical interaction ComPPI
RUVBL1 TUBB4B 25348397 N/A physical interaction ComPPI
RPA1 TUBB4B 25348397 N/A physical interaction ComPPI
PSMA1 TUBB4B 25348397 N/A physical interaction ComPPI
HEY1 TUBB4B 25348397 N/A physical interaction ComPPI
LRP1 TUBB4B 25348397 N/A physical interaction ComPPI
TUBA4A TUBB4B 25348397 N/A physical interaction ComPPI
CAD TUBB4B 25348397 N/A physical interaction ComPPI
COPB2 TUBB4B 25348397 N/A physical interaction ComPPI
RAB1A TUBB4B 25348397 N/A physical interaction ComPPI
ANG TUBB4B 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
XPO1 TUBB4B 25348397 N/A physical interaction ComPPI
RPA2 TUBB4B 25348397 N/A physical interaction ComPPI
RPA3 TUBB4B 25348397 N/A physical interaction ComPPI
TRAF1 TUBB4B 25348397 N/A physical interaction ComPPI
HUWE1 TUBB4B 25348397 N/A physical interaction ComPPI
SUMO2 TUBB4B 25348397 N/A physical interaction ComPPI
NEDD8 TUBB4B 25348397 N/A physical interaction ComPPI
CUL2 TUBB4B 25348397 N/A physical interaction ComPPI
CUL4B TUBB4B 25348397 N/A physical interaction ComPPI
ARRB2 TUBB4B 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 TUBB4B 25348397 N/A physical interaction ComPPI
CUL1 TUBB4B 25348397 N/A physical interaction ComPPI
CUL4A TUBB4B 25348397 N/A physical interaction ComPPI
EGFR TUBB4B 25348397 N/A physical interaction ComPPI
TUBA1A TUBB4B 25348397 N/A physical interaction ComPPI
YWHAE TUBB4B 25348397 N/A physical interaction ComPPI
VHL TUBB4B 25348397 N/A physical interaction ComPPI
CDC20 TUBB4B 25348397 N/A physical interaction ComPPI
PHB2 TUBB4B 25348397 N/A physical interaction ComPPI
RNF2 TUBB4B 25348397 N/A physical interaction ComPPI
GABARAP TUBB4B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC6 TUBB4B 25348397 N/A physical interaction ComPPI
CCNT1 TUBB4B 25348397 N/A physical interaction ComPPI
AICDA TUBB4B 25348397 N/A physical interaction ComPPI
MAP1LC3A TUBB4B 20562859 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4B DLST 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TUBB4B PSME1 25348397 N/A two hybrid,physical interaction ComPPI
TUBB4B DLEU1 25348397 N/A two hybrid ComPPI
TUBB4B SOCS6 12052866 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TUBB4B CDK9 25348397 N/A physical interaction ComPPI
TUBB4B MGMT 25348397 N/A physical interaction ComPPI
TUBB4B AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4B AGO4 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4B HDAC5 25348397 N/A physical interaction ComPPI
TUBB4B FBXO25 25348397 N/A physical interaction ComPPI
TUBB4B TERF1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TUBB4B TINF2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TUBB4B ACD 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TUBB4B POT1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TUBB4B COPS6 25348397 N/A physical interaction ComPPI
TUBB4B CAND1 25348397 N/A physical interaction ComPPI
TUBB4B SPRTN 25348397 N/A physical interaction ComPPI
TUBB4B AP2M1 25348397 N/A physical interaction ComPPI
TUBB4B LMAN1 25348397 N/A physical interaction ComPPI
TUBB4B TUBB2A 25348397 N/A physical interaction ComPPI
TUBB4B POLR2B 25348397 N/A physical interaction ComPPI
TUBB4B HADHA 25348397 N/A physical interaction ComPPI
TUBB4B SMURF1 25348397 N/A physical interaction ComPPI
TUBB4B FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
TUBB4B VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
TUBB4B IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4B PEX14 21525035 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TUBB4B HSP90AA2P 25348397 N/A physical interaction ComPPI
TUBB4B ITGA4 25348397 N/A physical interaction ComPPI
TUBB4B PAN2 25348397 N/A physical interaction ComPPI
TUBB4B ENOX2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TUBB4B PRKN 25348397 N/A physical interaction ComPPI
TUBB4B CDKN2A 25348397 N/A physical interaction ComPPI
TUBB4B MCTS1 25348397 N/A physical interaction ComPPI
TUBB4B PRCP 25348397 N/A physical interaction ComPPI
TUBB4B TUBA1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4B TUBB6 25348397 N/A physical interaction ComPPI
TUBB4B ASB17 25348397 N/A physical interaction ComPPI
TUBB4B ZBTB1 25348397 N/A physical interaction ComPPI
TUBB4B AIRE 25348397 N/A physical interaction ComPPI
TUBB4B AURKA 25348397 N/A physical interaction ComPPI
TUBB4B CEP250 25348397 N/A physical interaction ComPPI
TUBB4B HAUS2 25348397 N/A physical interaction ComPPI
TUBB4B CEP76 25348397 N/A physical interaction ComPPI
TUBB4B LGALS3BP 25348397 N/A physical interaction ComPPI
TUBB4B MAGED2 25348397 N/A physical interaction ComPPI
TUBB4B TP53 25348397 N/A physical interaction ComPPI
TUBB4B TUBGCP2 25348397 N/A physical interaction ComPPI
TUBB4B TUBGCP3 25348397 N/A physical interaction ComPPI
TUBB4B TUBGCP4 25348397 N/A physical interaction ComPPI
TUBB4B ALK 25348397 N/A physical interaction ComPPI
TUBB4B CUL7 25348397 N/A physical interaction ComPPI
TUBB4B OBSL1 25348397 N/A physical interaction ComPPI
TUBB4B CDK13 25348397 N/A physical interaction ComPPI
TUBB4B RPS6KB2 25348397 N/A physical interaction ComPPI
TUBB4B AKAP8 25348397 N/A physical interaction ComPPI
TUBB4B DNAJA2 25348397 N/A physical interaction ComPPI
TUBB4B HSPD1 25348397 N/A physical interaction ComPPI
TUBB4B RPL7 25348397 N/A physical interaction ComPPI
TUBB4B RPL8 25348397 N/A physical interaction ComPPI
TUBB4B RPS15A 25348397 N/A physical interaction ComPPI
TUBB4B SLC25A4 25348397 N/A physical interaction ComPPI
TUBB4B TUBA3C 25348397 N/A physical interaction ComPPI
TUBB4B PTEN 25348397 N/A physical interaction ComPPI
TUBB4B NPHP4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TUBB4B RPGR 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TUBB4B ID2 25348397 N/A physical interaction ComPPI
TUBB4B GAN 25348397 N/A physical interaction ComPPI
TUBB4B MID1 25348397 N/A physical interaction ComPPI
TUBB4B MID2 25348397 N/A physical interaction ComPPI
TUBB4B POU5F1 25348397 N/A physical interaction ComPPI
TUBB4B CYLD 25348397 N/A physical interaction ComPPI
TUBB4B TRIM25 25348397 N/A physical interaction ComPPI
TUBB4B CCND2 25348397 N/A physical interaction ComPPI
TUBB4B BRCA1 25348397 N/A physical interaction ComPPI
TUBB4B TES 25348397 N/A physical interaction ComPPI
TUBB4B RNF169 25348397 N/A physical interaction ComPPI
TUBB4B PPP2R2B 19156129 24234451 25348397 association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
TUBB4B GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B AKT1 20856200 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TUBB4B MEX3C 22863774 24234451 25348397 association pull down ComPPI,IntAct
TUBB4B LRRK2 24234451 24275654 25348397 physical association two hybrid ComPPI,IntAct
TUBB4B LRRK1 24234451 24947832 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUBB4B OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B NFKB1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
TUBB4B IFT27 24234451 25348397 27173435 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B WRAP73 24234451 25348397 26545777 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBB4B PPEF1 24234451 25348397 28330616 association pull down ComPPI,IntAct
TUBB4B KATNA1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBB4B KATNAL2 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBB4B KATNB1 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBB4B NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
TUBB4B DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
PPID TUBB4B 21146485 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SCG2 TUBB4B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ECPAS TUBB4B 25348397 N/A physical interaction ComPPI
ISOC1 TUBB4B 25348397 N/A physical interaction ComPPI
ATP6V1B2 TUBB4B 25348397 N/A physical interaction ComPPI
METTL3 TUBB4B 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 TUBB4B 24234451 29507755 association anti tag coimmunoprecipitation IntAct
TPT1 TUBB4B 24234451 27607350 association anti bait coimmunoprecipitation IntAct
IL7R TUBB4B 20167604 27898060 N/A N/A OmniPath
NUMA1 TUBB4B 11956313 27898060 stimulant N/A OmniPath

Visualization










  Return