Gene Information gene info

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GENE：TUBB6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBB6
FullNmae tubulin beta 6 class V
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20776
EnsembleID ENSG00000176014
Uniprot Q9BUF5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBB6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TUBB6 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBB6 GO:0000226,GO:0000278,GO:0003674,GO:0003924,GO:0005200,GO:0005515,GO:0005525,GO:0005634,GO:0005737,GO:0005874,GO:0005874,GO:0015630,GO:0045171,GO:0046872,GO:0070062,GO:0072686

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBB6 hsa:84617 path:hsa04145 Phagosome - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa04540 Gap junction - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05020 Prion disease - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBB6 hsa:84617 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TUBB6 IL7R 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 TUBB6 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TUBB6 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 TUBB6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TUBB6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TUBB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TUBB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUBB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TUBB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TUBB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 TUBB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A7F58 TUBB6 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PIK3R2 TUBB6 25348397 N/A physical interaction ComPPI
CTDSP2 TUBB6 25348397 N/A physical interaction ComPPI
ZNRD2 TUBB6 25348397 N/A physical interaction ComPPI
PCBP1 TUBB6 25348397 N/A physical interaction ComPPI
TRAF6 TUBB6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
KEAP1 TUBB6 25348397 N/A physical interaction ComPPI
MCM2 TUBB6 25348397 N/A physical interaction ComPPI
TUFM TUBB6 25348397 N/A physical interaction ComPPI
KATNAL1 TUBB6 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
PTPN18 TUBB6 25348397 N/A physical interaction ComPPI
CD81 TUBB6 25348397 N/A physical interaction ComPPI
SHC1 TUBB6 25348397 N/A physical interaction ComPPI
ARAF TUBB6 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN TUBB6 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
INPPL1 TUBB6 25348397 N/A physical interaction ComPPI
CUL3 TUBB6 25348397 N/A physical interaction ComPPI
CLU TUBB6 25348397 N/A physical interaction ComPPI
TUBA1B TUBB6 25348397 N/A physical interaction ComPPI
IRS4 TUBB6 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ILK TUBB6 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC TUBB6 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TNFRSF1A TUBB6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBA4A TUBB6 25348397 N/A physical interaction ComPPI
DUSP16 TUBB6 24234451 25348397 28330616 association pull down ComPPI,IntAct
CFTR TUBB6 25348397 N/A physical interaction ComPPI
ANG TUBB6 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
MTMR11 TUBB6 25348397 N/A physical interaction ComPPI
SUMO2 TUBB6 25348397 N/A physical interaction ComPPI
EGFR TUBB6 25348397 N/A physical interaction ComPPI
TUBA1A TUBB6 24234451 25348397 29568061 association pull down,physical interaction ComPPI,IntAct
YAP1 TUBB6 25348397 N/A physical interaction ComPPI
NOS2 TUBB6 25348397 N/A physical interaction ComPPI
TUBB4B TUBB6 25348397 N/A physical interaction ComPPI
STK4 TUBB6 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
VCAM1 TUBB6 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
HTRA2 TUBB6 25348397 N/A physical interaction ComPPI
PPP6C TUBB6 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKN TUBB6 25348397 N/A physical interaction ComPPI
CUL7 TUBB6 25348397 N/A physical interaction ComPPI
NFKB2 TUBB6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PEX14 TUBB6 21525035 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TRIM25 TUBB6 25348397 N/A physical interaction ComPPI
ESR1 TUBB6 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
RPS6KB2 TUBB6 25348397 N/A physical interaction ComPPI
BRCA1 TUBB6 25348397 N/A physical interaction ComPPI
MAP3K3 TUBB6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
SKI TUBB6 25348397 N/A physical interaction ComPPI
EIF3A TUBB6 25348397 N/A physical interaction ComPPI
NUCB2 TUBB6 25348397 N/A physical interaction ComPPI
PPEF2 TUBB6 25348397 N/A physical interaction ComPPI
KATNB1 TUBB6 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
IQCB1 TUBB6 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPM1D TUBB6 24234451 25348397 28330616 association pull down ComPPI,IntAct
TES TUBB6 25348397 N/A physical interaction ComPPI
IGSF8 TUBB6 25348397 N/A physical interaction ComPPI
L3MBTL1 TUBB6 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
TOMM40 TUBB6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CAMK1D TUBB6 25348397 N/A physical interaction ComPPI
SAV1 TUBB6 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LATS2 TUBB6 25348397 N/A physical interaction ComPPI
ICAM1 TUBB6 25348397 N/A physical interaction ComPPI
CYLD TUBB6 25348397 N/A physical interaction ComPPI
CCND2 TUBB6 25348397 N/A physical interaction ComPPI
SEC24A TUBB6 25348397 N/A physical interaction ComPPI
MTMR8 TUBB6 25348397 N/A physical interaction ComPPI
IFT27 TUBB6 24234451 25348397 27173435 association anti tag coimmunoprecipitation ComPPI,IntAct
TUBA1C TUBB6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO6 TUBB6 25348397 N/A physical interaction ComPPI
PCSK9 TUBB6 25348397 N/A physical interaction ComPPI
MAP3K1 TUBB6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
UBXN6 TUBB6 25348397 N/A physical interaction ComPPI
HTR7 TUBB6 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AHCYL1 TUBB6 25348397 N/A physical interaction ComPPI
SPRTN TUBB6 25348397 N/A physical interaction ComPPI
HERC2 TUBB6 24234451 25348397 29426014 association anti tag coimmunoprecipitation ComPPI,IntAct
FN1 TUBB6 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ASB12 TUBB6 25348397 N/A physical interaction ComPPI
NXF1 TUBB6 25348397 N/A physical interaction ComPPI
CAPZA2 TUBB6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MOV10 TUBB6 25348397 N/A physical interaction ComPPI
GAN TUBB6 25348397 N/A physical interaction ComPPI
RIPK4 TUBB6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
LRRK2 TUBB6 24234451 24275654 25348397 physical association two hybrid ComPPI,IntAct
DNAJA4 TUBB6 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSAT1 TUBB6 25348397 N/A physical interaction ComPPI
SRXN1 TUBB6 25348397 N/A physical interaction ComPPI
METTL23 TUBB6 25348397 N/A physical interaction ComPPI
CCDC8 TUBB6 25348397 N/A physical interaction ComPPI
CTDNEP1 TUBB6 25348397 N/A physical interaction ComPPI
EEF1AKMT3 TUBB6 25348397 N/A physical interaction ComPPI
CAMKMT TUBB6 25348397 N/A physical interaction ComPPI
TUBB6 SULT1A1 25348397 N/A physical interaction ComPPI
TUBB6 FAM86B2 25348397 N/A physical interaction ComPPI
TUBB6 ASB10 25348397 N/A physical interaction ComPPI
TUBB6 KATNAL2 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
TUBB6 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
DUX4 TUBB6 24234451 25348397 26816005 association pull down ComPPI,IntAct
NUMA1 TUBB6 11956313 27898060 stimulant N/A OmniPath

Visualization










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