Gene Information gene info

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GENE：TUBB8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUBB8
FullNmae tubulin beta 8 class VIII
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20773
EnsembleID ENSG00000261456
Uniprot Q3ZCM7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUBB8 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUBB8 GO:0000226,GO:0000278,GO:0001556,GO:0003674,GO:0003924,GO:0005200,GO:0005525,GO:0005737,GO:0005874,GO:0007056,GO:0015630,GO:0045171,GO:0046872,GO:0070062,GO:0072686,GO:0072687

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUBB8 hsa:347688 path:hsa04145 Phagosome - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa04540 Gap junction - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa04814 Motor proteins - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05010 Alzheimer disease - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05012 Parkinson disease - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05016 Huntington disease - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05020 Prion disease - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
TUBB8 hsa:347688 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDC73 TUBB8 25348397 N/A physical interaction ComPPI
STK16 TUBB8 25348397 N/A physical interaction ComPPI
TUBB TUBB8 25348397 N/A physical interaction ComPPI
KEAP1 TUBB8 25348397 N/A physical interaction ComPPI
PPP1R15A TUBB8 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
CDC16 TUBB8 25348397 N/A physical interaction ComPPI
SERPINC1 TUBB8 25348397 N/A physical interaction ComPPI
KNG1 TUBB8 25348397 N/A physical interaction ComPPI
IRF3 TUBB8 25348397 N/A physical interaction ComPPI
PRG2 TUBB8 25348397 N/A physical interaction ComPPI
LRP1 TUBB8 25348397 N/A physical interaction ComPPI
XPO1 TUBB8 25348397 N/A physical interaction ComPPI
SOX2 TUBB8 25348397 N/A physical interaction ComPPI
CD70 TUBB8 25348397 N/A physical interaction ComPPI
CTDSP1 TUBB8 25348397 N/A physical interaction ComPPI
MME TUBB8 17342744 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ANTXR1 TUBB8 25348397 N/A physical interaction ComPPI
DNAJB11 TUBB8 25348397 N/A physical interaction ComPPI
XCL1 TUBB8 25348397 N/A physical interaction ComPPI
PEX14 TUBB8 21525035 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
IL12RB1 TUBB8 25348397 N/A physical interaction ComPPI
CD79A TUBB8 25348397 N/A physical interaction ComPPI
GDF9 TUBB8 25348397 N/A physical interaction ComPPI
BRCA1 TUBB8 25348397 N/A physical interaction ComPPI
EFNB3 TUBB8 25348397 N/A physical interaction ComPPI
DCP2 TUBB8 25348397 N/A physical interaction ComPPI
KATNA1 TUBB8 24234451 25348397 26929214 association tandem affinity purification ComPPI,IntAct
PRKAG1 TUBB8 25348397 N/A physical interaction ComPPI
IQCB1 TUBB8 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EEF1D TUBB8 25348397 N/A physical interaction ComPPI
GNAZ TUBB8 25348397 N/A physical interaction ComPPI
ICAM1 TUBB8 25348397 N/A physical interaction ComPPI
CHRM3 TUBB8 25348397 N/A physical interaction ComPPI
WNT7A TUBB8 25348397 N/A physical interaction ComPPI
AURKC TUBB8 25348397 N/A physical interaction ComPPI
SIRT6 TUBB8 25348397 N/A physical interaction ComPPI
FBL TUBB8 25348397 N/A physical interaction ComPPI
IL1R1 TUBB8 25348397 N/A physical interaction ComPPI
POU5F1 TUBB8 25348397 N/A physical interaction ComPPI
TUBA1C TUBB8 25348397 N/A physical interaction ComPPI
PSG1 TUBB8 25348397 N/A physical interaction ComPPI
LGALS7 TUBB8 25348397 N/A physical interaction ComPPI
RPS27 TUBB8 25348397 N/A physical interaction ComPPI
KLK5 TUBB8 25348397 N/A physical interaction ComPPI
KSR1 TUBB8 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
TOR1AIP2 TUBB8 25348397 N/A physical interaction ComPPI
HCFC2 TUBB8 25348397 N/A physical interaction ComPPI
MAP3K1 TUBB8 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CDK13 TUBB8 25348397 N/A physical interaction ComPPI
AVIL TUBB8 25348397 N/A physical interaction ComPPI
BCAR1 TUBB8 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
ERBB3 TUBB8 25348397 N/A physical interaction ComPPI
CCAR2 TUBB8 25348397 N/A physical interaction ComPPI
G3BP1 TUBB8 25348397 N/A physical interaction ComPPI
GAN TUBB8 25348397 N/A physical interaction ComPPI
TUBB2A TUBB8 25348397 N/A physical interaction ComPPI
TUBB2B TUBB8 25348397 N/A physical interaction ComPPI
TAF5L TUBB8 25348397 N/A physical interaction ComPPI
DLK1 TUBB8 25348397 N/A physical interaction ComPPI
LRIG1 TUBB8 25348397 N/A physical interaction ComPPI
TUBB8 IDS 25348397 N/A physical interaction ComPPI
TUBB8 CCNJL 25348397 N/A physical interaction ComPPI
TUBB8 TBL1Y 25348397 N/A physical interaction ComPPI

Visualization










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