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GENE：UBE2N

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2N
FullNmae ubiquitin conjugating enzyme E2 N
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12492
EnsembleID ENSG00000177889
Uniprot P61088

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2N pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBE2N parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UBE2N autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2N GO:0000151,GO:0000724,GO:0000729,GO:0003723,GO:0004842,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006282,GO:0006301,GO:0006301,GO:0016567,GO:0016567,GO:0031371,GO:0031372,GO:0031372,GO:0031625,GO:0032991,GO:0033182,GO:0035370,GO:0035370,GO:0043123,GO:0043130,GO:0043161,GO:0045739,GO:0050852,GO:0051092,GO:0061631,GO:0061631,GO:0061631,GO:0061631,GO:0061631,GO:0070062,GO:0070534,GO:0070534,GO:0070534,GO:0097027,GO:0140374,GO:1902523,GO:1902533,GO:1904262,GO:2000781

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2N hsa:7334 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
UBE2N hsa:7334 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UBE2N PCNA 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655 26192618 interaction type N/A ACSN
UBE2N TP53BP1 17349954 17652783 18196958 19203579 19258535 19793861 19793862 19841479 19851286 22771115 26192618 interaction type N/A ACSN
TRAF6 UBE2N 15147900 23180781 physical association two hybrid InnateDB
UBE2N BCL10 14695475 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
UBE2N UBA1 18570872 19734906 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2N BIRC2 18570872 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2N BIRC3 18570872 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2N RIPK1 18570872 19734906 23180781 ubiquitination reaction enzymatic study InnateDB
MALT1 UBE2N 14695475 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2N PELI1 19734906 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2N UBE2D1 19483718 23180781 ubiquitination reaction enzymatic study InnateDB
UBE2N UBE2V1 21460221 23180781 24145445 26101372 deubiquitination reaction,ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study,ubiquitinase assay InnateDB
ISG15 UBE2N 16009940 16122702 23180781 enzymatic reaction,physical association enzymatic study,unspecified method InnateDB
UBE2V2 UBE2N 16122702 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
UBE2N OTUB1 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
STUB1 UBE2N 23180781 24145445 physical association anti tag coimmunoprecipitation InnateDB
UBE2N UBE2V2 23180781 26101372 ubiquitination reaction ubiquitinase assay InnateDB
UBE2N TRIM5 23180781 26101372 ubiquitination reaction ubiquitinase assay InnateDB
UBE2N UBE2N 14713952 20551964 26467481 ubiquitination reaction,bind,up-regulates activity N/A Signor

Source Target Pmid Interactiontype Methods Database
BCL10 UBE2N 20005715 interaction type N/A PSP
PRKAB1 UBE2N 20005715 interaction type N/A PSP
TRAF2 UBE2N 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
ETS1 UBE2N 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 UBE2N 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UBE2N 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBE2N 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2N 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UBE2N 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBE2N 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UBE2N 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 UBE2N 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000016FF9C UBE2N 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000070B1D UBE2N 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE UBE2N 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D UBE2N 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000004BACE UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD6DC UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 UBE2N 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002AAD6B UBE2N 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 UBE2N 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 UBE2N 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006A1CB UBE2N 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000002103A UBE2N 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 UBE2N 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 UBE2N 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 UBE2N 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 UBE2N 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 UBE2N 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B2B UBE2N 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 UBE2N 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EBD4B UBE2N 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000009262D UBE2N 25327529 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
IL1B UBE2N 25361965 interaction type N/A PTMCode2
UBE2N IL1B 25361965 interaction type N/A PTMCode2
AURKA UBE2N 25361965 interaction type N/A PTMCode2
UBE2N AURKA 25361965 interaction type N/A PTMCode2
HLTF UBE2N 25361965 interaction type N/A PTMCode2
UBE2N HLTF 25361965 interaction type N/A PTMCode2
BCL10 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N BCL10 25361965 interaction type N/A PTMCode2
RNF103 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N RNF103 25361965 interaction type N/A PTMCode2
RNF11 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N RNF11 25361965 interaction type N/A PTMCode2
STUB1 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N STUB1 25361965 interaction type N/A PTMCode2
BIRC3 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N BIRC3 25361965 interaction type N/A PTMCode2
UBE2N TRAF6 25361965 interaction type N/A PTMCode2
TRAF6 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N ZNRF2 25361965 interaction type N/A PTMCode2
ZNRF2 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N UBE2V2 25361965 interaction type N/A PTMCode2
UBE2V2 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N STAMBPL1 25361965 interaction type N/A PTMCode2
STAMBPL1 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N RNF8 25361965 interaction type N/A PTMCode2
RNF8 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N TRIM32 25361965 interaction type N/A PTMCode2
TRIM32 UBE2N 25361965 interaction type N/A PTMCode2
UBE2N PCNA 25361965 interaction type N/A PTMCode2
PCNA UBE2N 25361965 interaction type N/A PTMCode2
UBE2N TNF 25361965 interaction type N/A PTMCode2
TNF UBE2N 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SF3A3 UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SNRPB2 UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SNW1 UBE2N 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L UBE2N 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CBSL UBE2N 25348397 N/A physical interaction ComPPI
TRIM21 UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
VASP UBE2N 25348397 N/A physical interaction ComPPI
BAG3 UBE2N 25348397 N/A physical interaction ComPPI
LDHB UBE2N 25348397 N/A physical interaction ComPPI
ISG15 UBE2N 25348397 N/A physical interaction ComPPI
VIM UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TNFAIP3 UBE2N 25348397 N/A physical interaction ComPPI
CHIC2 UBE2N 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TRAF6 UBE2N 14525934 15147900 19465916 19549727 24234451 25348397 27173435 ubiquitination reaction,association,physical association two hybrid,molecular sieving,surface plasmon resonance,x-ray crystallography,physical interaction,two hybrid array,enzymatic study,tandem affinity purification,surface plasmon resonance array,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
CALM1 UBE2N 25348397 N/A physical interaction,ubiquitinase assay ComPPI
XIAP UBE2N 19549727 24234451 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
TRIM32 UBE2N 17994549 19549727 19690564 21143188 24234451 25348397 27173435 27898060 association,physical association two hybrid,physical interaction,two hybrid array,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct,OmniPath
MKRN3 UBE2N 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DCUN1D1 UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
CYCS UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MARCHF5 UBE2N 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TXNDC17 UBE2N 25348397 N/A physical interaction ComPPI
UBE2E2 UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
BIRC8 UBE2N 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF5 UBE2N 25348397 N/A physical interaction ComPPI
GGA2 UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
APPL1 UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
POLI UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
RNF115 UBE2N 25348397 N/A physical interaction ComPPI
ZYX UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CBLB UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
RNF111 UBE2N 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
SND1 UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRKACA UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SIAH1 UBE2N 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
THRA UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
PDIA3 UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SLC2A4 UBE2N 14525934 16396496 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ACOX1 UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
HGS UBE2N 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBC UBE2N 25348397 N/A physical interaction ComPPI
DLD UBE2N 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
HSP90AA1 UBE2N 16307917 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
UBE2N RNF128 12705856 14525934 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
UBE2N AURKA 12881723 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
UBE2N UBE2V1 11057907 16307917 19549727 24234451 25260751 25348397 ubiquitination reaction,association,physical association two hybrid,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,enzymatic study,in vitro,ubiquitinase assay,inference by socio-affinity scoring ComPPI,IntAct
UBE2N UBE2V2 11473244 11473255 14525934 18316726 19549727 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,x-ray crystallography,physical interaction,in vitro,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
UBE2N RNF11 14525934 15231748 19549727 19690564 24234451 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study,two hybrid ComPPI,HPRD,IntAct
UBE2N CHUK 25348397 N/A physical interaction ComPPI
UBE2N TRAF2 25348397 N/A physical interaction ComPPI
UBE2N HLTF 18316726 18719106 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
UBE2N OTUB1 19615732 24234451 25348397 26752685 27173435 association,physical association anti tag coimmunoprecipitation,fluorescence polarization spectroscopy,pull down,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
UBE2N STAMBPL1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2N TP53 25348397 N/A physical interaction ComPPI
UBE2N AMFR 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N BIRC3 19690564 24234451 25260751 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,ubiquitinase assay ComPPI,IntAct
UBE2N CADPS2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N CNOT4 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N DTX1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RNF103 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N LRSAM1 19549727 19690564 24234451 25260751 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,ubiquitinase assay ComPPI,IntAct
UBE2N MIB1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N MID2 25348397 N/A physical interaction ComPPI
UBE2N NEURL1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N NFX1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N PJA2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RNF13 19690564 24234451 25260751 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,ubiquitinase assay ComPPI,IntAct
UBE2N RNF130 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RNF152 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RNF165 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RNF167 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RNF182 19690564 24234451 25260751 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,ubiquitinase assay ComPPI,IntAct
UBE2N RNF43 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N SH3RF2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N TOPORS 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N ZNRF1 19549727 19690564 24234451 25348397 27173435 association,physical association two hybrid,physical interaction,two hybrid array,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
UBE2N ZNRF2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
UBE2N ZNRF3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N ZNRF4 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N DZIP3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N MID1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RC3H2 19549727 24234451 25348397 26489670 27898060 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct,OmniPath
UBE2N RNF8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RBCK1 19549727 24234451 25260751 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,ubiquitinase assay ComPPI,IntAct
UBE2N RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N MARCHF7 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N CHFR 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N RFWD3 19549727 24234451 25260751 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,ubiquitinase assay ComPPI,IntAct
UBE2N TRIM25 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N TRIM5 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2N STUB1 16307917 24234451 25036637 25260751 25348397 ubiquitination reaction,association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,ubiquitinase assay ComPPI,IntAct
UBE2N HSP90AA2P 25348397 N/A physical interaction ComPPI
UBE2N PEDS1 11057907 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
UBE2N OTUB2 25348397 N/A physical interaction ComPPI
UBE2N RNF168 19203578 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2N HERC2 25348397 N/A physical interaction ComPPI
UBE2N HERC2P3 25348397 N/A physical interaction ComPPI
UBE2N BRCA1 25348397 N/A physical interaction ComPPI
UBE2N ELAVL1 25348397 N/A physical interaction ComPPI
UBE2N RAD23A 25348397 N/A physical interaction ComPPI
UBE2N SHPRH 25348397 N/A anti tag coimmunoprecipitation,pull down,physical interaction,physical interaction ComPPI
UBE2N TRIM11 24234451 25260751 25348397 27173435 ubiquitination reaction,association,physical association physical interaction,tandem affinity purification,ubiquitinase assay,inference by socio-affinity scoring ComPPI,IntAct
UBE2N TRIM50 25348397 N/A physical interaction ComPPI
UBE2N TRIM27 25348397 N/A physical interaction ComPPI
UBE2N CDK2 25348397 N/A physical interaction ComPPI
UBE2N RIPK1 25348397 N/A physical interaction ComPPI
UBE2N UBA1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
UBE2N PC 25348397 N/A physical interaction ComPPI
UBE2N PCCA 25348397 N/A physical interaction ComPPI
UBE2N ACACA 25348397 N/A physical interaction ComPPI
UBE2N PCCB 25348397 N/A physical interaction ComPPI
UBE2N PRKN 25348397 N/A physical interaction ComPPI
UBE2N TRIM28 25348397 N/A physical interaction ComPPI
UBE2N MIB2 25348397 N/A physical interaction ComPPI
UBE2N MYLIP 25348397 N/A physical interaction ComPPI
UBE2N SH3RF1 25348397 N/A physical interaction ComPPI
UBE2N RNF122 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
UBE2N TRIM17 25348397 N/A physical interaction ComPPI
UBE2N TRIM39 25348397 N/A physical interaction ComPPI
UBE2N BARD1 25348397 N/A physical interaction ComPPI
UBE2N ATP6V1H 25348397 N/A physical interaction ComPPI
UBE2N VPS33B 25348397 N/A physical interaction ComPPI
UBE2N ZDHHC5 25348397 N/A physical interaction ComPPI
UBE2N SARDH 25348397 N/A physical interaction ComPPI
UBE2N UFD1 25348397 N/A physical interaction ComPPI
UBE2N USP14 25348397 N/A physical interaction ComPPI
UBE2N ACTR2 25348397 N/A physical interaction ComPPI
UBE2N NBN 25348397 N/A physical interaction ComPPI
UBE2N RNF126 25348397 N/A physical interaction ComPPI
UBE2N FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
UBE2N VCAM1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
UBE2N PELI3 25348397 N/A physical interaction ComPPI
UBE2N TRIM72 25348397 N/A physical interaction ComPPI
UBE2N ARIH1 25348397 N/A physical interaction ComPPI
UBE2N MFN2 25348397 N/A physical interaction ComPPI
UBE2N TNF 25348397 N/A physical interaction ComPPI
UBE2N TRIM33 25348397 N/A physical interaction ComPPI
UBE2N BFAR 19549727 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2N MALT1 25348397 N/A physical interaction ComPPI
UBE2N RHNO1 25348397 N/A physical interaction ComPPI
UBE2N MDM2 25348397 N/A physical interaction ComPPI
UBE2N DTL 25348397 N/A physical interaction ComPPI
UBE2N ATP2B3 25348397 N/A physical interaction ComPPI
UBE2N ACOT13 25348397 N/A physical interaction ComPPI
UBE2N ASPDH 25348397 N/A physical interaction ComPPI
UBE2N CAB39 25348397 N/A physical interaction ComPPI
UBE2N FH 25348397 N/A physical interaction ComPPI
UBE2N HADH 25348397 N/A physical interaction ComPPI
UBE2N HNRNPA3 25348397 N/A physical interaction ComPPI
UBE2N HSPB1 25348397 N/A physical interaction ComPPI
UBE2N IDH3A 25348397 N/A physical interaction ComPPI
UBE2N LDHAL6A 25348397 N/A physical interaction ComPPI
UBE2N LDHC 25348397 N/A physical interaction ComPPI
UBE2N LGALS1 25348397 N/A physical interaction ComPPI
UBE2N PHGDH 25348397 N/A physical interaction ComPPI
UBE2N RAD23B 25348397 N/A physical interaction ComPPI
UBE2N SF1 25348397 N/A physical interaction ComPPI
UBE2N UBE2K 25348397 N/A physical interaction ComPPI
UBE2N UBL5 25348397 N/A physical interaction ComPPI
UBE2N KIF1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2N PPIA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2N RC3H1 25348397 N/A physical interaction ComPPI
UBE2N CNEP1R1 25348397 N/A physical interaction ComPPI
UBE2N RNF181 25348397 N/A physical interaction ComPPI
UBE2N RNF4 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
UBE2N EPM2A 25348397 N/A physical interaction ComPPI
UBE2N NHLRC1 25348397 N/A physical interaction ComPPI
UBE2N F12 25348397 N/A physical interaction ComPPI
UBE2N TRIM69 25348397 N/A physical interaction ComPPI
UBE2N TRIM63 25348397 N/A physical interaction ComPPI
UBE2N DERL1 25348397 N/A physical interaction ComPPI
UBE2N PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N ANXA5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N NANS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N TRAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N PLS3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N PPA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N IDH2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N MRPL12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N SLC25A10 25348397 N/A physical interaction ComPPI
UBE2N CRNN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N ZNF207 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N MED15 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
UBE2N CPNE3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N CS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N PYGL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N DNAJC8 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N CPSF6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N SF3A1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N ECHS1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N SRP68 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N MYL12B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N AIMP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N CBS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N ARPC4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N GARS1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N ATP5F1E 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N VCL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N EIF3M 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N SDCCAG8 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
UBE2N PRPF31 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
UBE2N SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBE2N TRIM23 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
UBE2N BIRC2 25348397 N/A physical interaction ComPPI
UBE2N RHBDF2 25348397 N/A physical interaction ComPPI
UBE2N VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2N PINX1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2N NME2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2N PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2N IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBE2N RIOK3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N RBP2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N UBE2E1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N UBE2D3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N NUDT6 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N INTS3 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N MFSD6 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N SLC9B2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N ANKRD13D 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N ANKRD13A 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N RNF135 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N DBF4B 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N RHBDD1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N RNF34 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N TRIM52 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N BIRC7 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N TSPAN17 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N PELI2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N SMURF1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N CCDC69 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N HIP1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N DNAJB6 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N HIP1R 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N FKBP6 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N KRT36 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N CD74 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N DNAJB2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N EPHA1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N GRIPAP1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N CEP85 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N DCUN1D2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N FAM184A 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N DENND6B 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N BAP1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N FAF2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N CRELD1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N CARD14 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N ASCC2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N ILRUN 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N CUEDC1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N IMPACT 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N APEX2 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N HBS1L 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N EPN1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2N PHOSPHO1 24234451 25348397 28330616 association pull down ComPPI,IntAct
UBE2N AIFM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HMGB1 UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NEDD4L UBE2N 25348397 N/A physical interaction ComPPI
BCL10 UBE2N 14525934 14695475 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ARF4 UBE2N 25348397 N/A physical interaction ComPPI
ARIH2 UBE2N 25348397 N/A physical interaction ComPPI
ADRM1 UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MNS1 UBE2N 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
HPRT1 UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MUL1 UBE2N 25348397 N/A physical interaction ComPPI
PELI1 UBE2N 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
GNPNAT1 UBE2N 25348397 N/A physical interaction ComPPI
UBE2N UBB 14525934 16129784 N/A experimental interaction detection HPRD
CALM2 UBE2N 24234451 25260751 ubiquitination reaction,physical association ubiquitinase assay,inference by socio-affinity scoring IntAct
OTUB-1 UBE2N 22367539 24234451 N/A fluorescence polarization spectroscopy,x-ray crystallography IntAct
STK38L UBE2N 24234451 30108113 association proximity-dependent biotin identification IntAct
UBE2N MAP3K7 10702308 17079228 17965022 27898060 inhibition N/A OmniPath
UBE2N TRAF2 11057907 14713952 18635759 18981220 20047764 20185725 20577214 21765415 22184250 23007157 23453969 27898060 stimulant N/A OmniPath
TRAF2 UBE2N 11057907 14713952 18635759 20047764 20185725 20577214 21765415 22184250 23007157 23453969 27898060 stimulant N/A OmniPath
OTUB1 UBE2N 19615732 20725033 21130715 21763684 22367539 22679021 24071738 24145445 25872870 26752685 27898060 inhibition N/A OmniPath
RIPK2 UBE2N 17947236 27898060 8837778 N/A N/A OmniPath
UBE2N RIPK2 17947236 27898060 8837778 N/A N/A OmniPath
UBE2N PCNA 18772547 27898060 stimulant N/A OmniPath
UBE2N TRAF6 11057907 15147900 15327770 1551980 17327397 17709375 18617513 18710948 18981220 19136968 19465916 19549727 19810754 20185725 21113135 21765415 21872579 23885119 24610907 25548215 27898060 inhibition,stimulant N/A OmniPath
TRAF6 UBE2N 11057907 15147900 15327770 17327397 17709375 18617513 18710948 19136968 19465916 19549727 19810754 20185725 21113135 21765415 23885119 24610907 25548215 27898060 stimulant N/A OmniPath
UBE2N IKBKG 11057907 12867425 14695475 15125833 15620648 17562858 17728323 17947236 27898060 N/A N/A OmniPath
UBE2N NFKBIA 11087742 12514169 17965022 27898060 7739562 7796813 7862124 7878466 8657102 N/A N/A OmniPath
RNF8 UBE2N 16215985 18678647 19549727 20023648 21911360 22589545 22814251 23255131 24732096 25909880 26285145 27898060 stimulant N/A OmniPath
UBE2N H2AX 17709392 18077395 27898060 inhibition,stimulant N/A OmniPath
UBE2N BIRC3 16547522 18570872 19690564 27898060 N/A N/A OmniPath
UBE2N RIPK1 18570872 19734906 27898060 N/A N/A OmniPath
UBE2N ISG15 16009940 16112642 16122702 22693631 27898060 N/A N/A OmniPath
HSPB1 UBE2N 18950704 27898060 stimulant N/A OmniPath
UBE2N IKBKB 10094049 10195894 10837071 15327770 15620648 15691841 16186825 16260493 17965022 27898060 N/A N/A OmniPath
UBE2N UBE2V1 10089880 11057907 11406273 12039045 15147900 15492226 1551980 16129784 16215985 16307917 17709375 18029035 18082144 18678647 19549727 20551964 20613989 21460221 22367539 22939629 24145445 25548215 26344197 27898060 stimulant N/A OmniPath

Visualization










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