Gene Information gene info

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GENE：USP30

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP30
FullNmae ubiquitin specific peptidase 30
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20065
EnsembleID ENSG00000135093
Uniprot Q70CQ3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP30 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
USP30 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
USP30 GO:0000422,GO:0000422,GO:0000425,GO:0004197,GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005739,GO:0005741,GO:0005741,GO:0005778,GO:0005829,GO:0008053,GO:0016579,GO:0016579,GO:0035871,GO:0044313,GO:0101005,GO:1901525

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
USP30 hsa:84749 path:hsa04137 Mitophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 USP30 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 USP30 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 USP30 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA USP30 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 USP30 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP30 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF USP30 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D USP30 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE USP30 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TOMM22 USP30 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
UBB USP30 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction,protease assay,protein cleavage,bio-layer interferometry,deubiquitinase assay ComPPI
UBC USP30 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction,protease assay,protein cleavage,bio-layer interferometry,deubiquitinase assay ComPPI
RPS27A USP30 25348397 N/A anti tag coimmunoprecipitation,physical interaction,protease assay,protein cleavage,bio-layer interferometry,deubiquitinase assay ComPPI
UBA52 USP30 25348397 N/A anti tag coimmunoprecipitation,physical interaction,protease assay,protein cleavage,bio-layer interferometry,deubiquitinase assay ComPPI
APC USP30 25348397 N/A physical interaction ComPPI
PVR USP30 25348397 N/A physical interaction ComPPI
SF3A1 USP30 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKN USP30 25348397 N/A physical interaction ComPPI
QKI USP30 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD79A USP30 25348397 N/A physical interaction ComPPI
TOMM20 USP30 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EXOSC7 USP30 25348397 N/A physical interaction ComPPI
C1QB USP30 25348397 N/A physical interaction ComPPI
AIFM1 USP30 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EXT2 USP30 25348397 N/A physical interaction ComPPI

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