Gene Information gene info

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GENE：VPS28

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VPS28
FullNmae VPS28 subunit of ESCRT-I
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18178
EnsembleID ENSG00000160948
Uniprot Q9UK41

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VPS28 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
VPS28 GO:0000813,GO:0000813,GO:0000813,GO:0000813,GO:0000813,GO:0005515,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0010008,GO:0010008,GO:0010008,GO:0016236,GO:0031397,GO:0031902,GO:0036258,GO:0036258,GO:0039702,GO:0043130,GO:0043162,GO:0043162,GO:0043328,GO:0043328,GO:0044877,GO:0045732,GO:0070062,GO:0090148,GO:2000397

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VPS28 hsa:51160 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 VPS28 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 VPS28 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 VPS28 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR VPS28 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005FDE70 VPS28 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 VPS28 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B968D VPS28 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 VPS28 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B9F58 VPS28 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD231 VPS28 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003CC709 VPS28 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE VPS28 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000243FF1 VPS28 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GOLGA2 VPS28 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS37C VPS28 25348397 N/A physical interaction ComPPI
SKIL VPS28 21516116 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RASSF5 VPS28 25348397 N/A two hybrid,physical interaction ComPPI
SAXO1 VPS28 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SMN1 VPS28 21516116 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,bimolecular fluorescence complementation,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS37B VPS28 14525934 15218037 21516116 24234451 25348397 26871637 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
ASF1A VPS28 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CD2AP VPS28 17853893 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GRB2 VPS28 25348397 N/A physical interaction ComPPI
UBB VPS28 25348397 N/A in vitro ComPPI
UBC VPS28 11916981 24234451 25348397 N/A pull down,physical interaction,in vitro ComPPI,IntAct
RPS27A VPS28 25348397 N/A in vitro ComPPI
UBA52 VPS28 11916981 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
AKAP11 VPS28 25348397 N/A physical interaction ComPPI
PARD6B VPS28 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BLZF1 VPS28 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BRCA2 VPS28 25348397 N/A physical interaction ComPPI
XPO1 VPS28 25348397 N/A physical interaction ComPPI
CEP55 VPS28 17853893 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CBX5 VPS28 25348397 N/A physical interaction ComPPI
STXBP4 VPS28 25348397 N/A physical interaction ComPPI
BCR VPS28 25348397 N/A physical interaction ComPPI
GABARAP VPS28 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MBIP VPS28 25348397 N/A physical interaction ComPPI
PDCD6IP VPS28 12588984 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
RGPD5 VPS28 25348397 N/A physical interaction ComPPI
TRIM27 VPS28 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS28 ALG2 25348397 N/A physical interaction ComPPI
VPS28 UBAP1 25348397 N/A physical interaction ComPPI
VPS28 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
VPS28 VPS52 21516116 24234451 25348397 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS28 TCF4 25348397 N/A physical interaction ComPPI
VPS28 TRIM54 25348397 N/A physical interaction ComPPI
VPS28 CARD9 25348397 N/A physical interaction ComPPI
VPS28 USHBP1 24234451 25348397 25416956 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
VPS28 INCA1 25348397 N/A physical interaction ComPPI
VPS28 DCAF6 25348397 N/A physical interaction ComPPI
VPS28 MAD1L1 25348397 N/A physical interaction ComPPI
VPS28 HAUS8 25348397 N/A physical interaction ComPPI
VPS28 DPYSL2 25348397 N/A physical interaction ComPPI
VPS28 HIP1R 25348397 N/A physical interaction ComPPI
VPS28 CEP57L1 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
VPS28 PCP2 25348397 N/A physical interaction ComPPI
VPS28 KNL1 25348397 N/A physical interaction ComPPI
HRS VPS28 25348397 N/A physical interaction ComPPI
VPS28 NEUR 25348397 N/A anti tag coimmunoprecipitation ComPPI
VPS28 TAK1 25348397 N/A anti tag coimmunoprecipitation ComPPI
VPS28 HH 25348397 N/A physical interaction ComPPI

Visualization










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