GENE:VPS37B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | VPS37B |
| FullNmae | VPS37B subunit of ESCRT-I |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25754 |
| EnsembleID | ENSG00000139722 |
| Uniprot | Q9H9H4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| VPS37B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| VPS37B | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| VPS37B | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| VPS37B | GO:0000813,GO:0000813,GO:0000813,GO:0000813,GO:0005515,GO:0005737,GO:0005768,GO:0005886,GO:0006612,GO:0006623,GO:0010008,GO:0010008,GO:0010008,GO:0016236,GO:0019076,GO:0030496,GO:0031902,GO:0036258,GO:0036258,GO:0039702,GO:0043162,GO:0043328,GO:0048306,GO:0070062,GO:0090148,GO:1903774 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| VPS37B | hsa:79720 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | VPS37B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | VPS37B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | VPS37B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | VPS37B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | VPS37B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | VPS37B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | VPS37B | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | VPS37B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000451A1 | VPS37B | 20371350 23446348 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS00000EED18 | VPS37B | 20371350 23446348 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS000041FA2C | VPS37B | 23592263 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS0000013DD8 | VPS37B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001597DC | VPS37B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000057FDB8 | VPS37B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000235862 | VPS37B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB0E | VPS37B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000010BD8D | VPS37B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019D79B | VPS37B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000364FEF | VPS37B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001799A3 | VPS37B | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C3AC1 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003758F0 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F5B39 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C7B2B | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000480E22 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000043B1D | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B1B47 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000025307A | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000328C0D | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CE28 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000C73C | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000521626 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003BBF48 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | VPS37B | 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | VPS37B | 22473208 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003ACE11 | VPS37B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DE2FC | VPS37B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A608 | VPS37B | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NCK2 | VPS37B | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| BYSL | VPS37B | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CDC73 | VPS37B | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| PRKAA2 | VPS37B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBASH3A | VPS37B | 25348397 | N/A | two hybrid | ComPPI |
| UBASH3B | VPS37B | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| SH3KBP1 | VPS37B | 25348397 | N/A | physical interaction | ComPPI |
| SORBS3 | VPS37B | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| BAG3 | VPS37B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| DCUN1D1 | VPS37B | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| EXOC8 | VPS37B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VPS37B | TSG101 | 14525934 15218037 24234451 25348397 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| VPS37B | VPS28 | 14525934 15218037 21516116 24234451 25348397 26871637 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid | ComPPI,HPRD,IntAct |
| VPS37B | CEP55 | 17853893 24234451 25348397 | association | affinity chromatography technology,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VPS37B | WDR12 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | USP14 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | UNC13D | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | XPO1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | MVB12A | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | TLE5 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| VPS37B | ERCC1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| VPS37B | PRKAA1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| VPS37B | QARS1 | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VPS37B | SMARCD1 | 21516116 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| VPS37B | SH3YL1 | 21516116 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| VPS37B | FBF1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | DNAJB1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | NIF3L1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | RPRD1A | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | WARS1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | YBX1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | UBAP1 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | GRB2 | 25348397 | N/A | physical interaction | ComPPI |
| VPS37B | CD2AP | 17853893 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| VPS37B | HGS | 24234451 25348397 26871637 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| VPS37B | ENKD1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VPS37B | GORASP2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VPS37B | KDM1A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VPS37B | LNX1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VPS37B | PLEKHA7 | 24234451 25348397 28877994 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| XPO7 | VPS37B | 25348397 | N/A | physical interaction | ComPPI |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B3822 | VPS37B | 27087310 | direct interaction,inhibition | N/A | NPInter |
