Gene Information gene info

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GENE：WDR45

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WDR45
FullNmae WD repeat domain 45
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28912
EnsembleID ENSG00000196998
Uniprot Q9Y484

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WDR45 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WDR45 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WDR45 GO:0000045,GO:0000407,GO:0000422,GO:0005515,GO:0005829,GO:0006497,GO:0006914,GO:0009267,GO:0019898,GO:0019901,GO:0032266,GO:0032266,GO:0034045,GO:0034497,GO:0044804,GO:0080025,GO:1901981,GO:2000786

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WDR45 hsa:11152 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RHOB WDR45 19637314 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 WDR45 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 WDR45 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 WDR45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WDR45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 WDR45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 WDR45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WDR45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A WDR45 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 WDR45 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CLNS1A WDR45 25348397 N/A physical interaction ComPPI
XPO1 WDR45 25348397 N/A physical interaction ComPPI
MDM2 WDR45 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
DRD2 WDR45 25348397 N/A physical interaction ComPPI
HDAC11 WDR45 25348397 N/A physical interaction ComPPI
TALDO1 WDR45 25348397 N/A physical interaction ComPPI
EZR WDR45 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SPAST WDR45 25348397 N/A physical interaction ComPPI
SALL2 WDR45 25348397 N/A physical interaction ComPPI
DUSP26 WDR45 25348397 N/A physical interaction ComPPI
SLC25A11 WDR45 25348397 N/A physical interaction ComPPI
APP WDR45 25348397 N/A physical interaction ComPPI
ATG2A WDR45 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR45 ATG2B 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR45 LHX6 25348397 N/A physical interaction ComPPI
WDR45 CEP89 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
WDR45 POC1A 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
WDR45 XAGE1A 25348397 N/A physical interaction ComPPI
WDR45 WDR45 20562859 24234451 physical association anti tag coimmunoprecipitation IntAct

Visualization










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