GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
ARHGAP4 |
| FullNmae |
Rho GTPase activating protein 4 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:674 |
| EnsembleID |
ENSG00000089820 |
| Uniprot |
P98171 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| ARHGAP4 |
autophagy |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| ARHGAP4 |
GO:0005096,GO:0005515,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005874,GO:0007010,GO:0007266,GO:0007399,GO:0010764,GO:0030336,GO:0030426,GO:0030517,GO:0051056 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
ARHGAP4 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
ARHGAP4 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| TAL1 |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| VDR |
ARHGAP4 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| PCBP1 |
ARHGAP4 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FMNL1 |
ARHGAP4 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FASLG |
ARHGAP4 |
16318909
24234451
25348397
|
physical association |
pull down |
ComPPI,IntAct |
| TRIM25 |
ARHGAP4 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ROBO1 |
ARHGAP4 |
25348397
|
N/A |
physical interaction,surface plasmon resonance array |
ComPPI |
| NRAS |
ARHGAP4 |
25348397
|
N/A |
in vitro |
ComPPI |
| MAP3K1 |
ARHGAP4 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HMGN2 |
ARHGAP4 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
| H2BC9 |
ARHGAP4 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
Visualization