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GENE：ARNTL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARNTL
FullNmae basic helix-loop-helix ARNT like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:701
EnsembleID ENSG00000133794
Uniprot O00327

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARNTL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARNTL autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ARNTL HIF1A 23180781 25416956 physical association two hybrid InnateDB
ARNTL MTNR1B 23180781 25939854 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 ARNTL 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ARNTL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ARNTL 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ARNTL 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C ARNTL 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP63 ARNTL 17521434 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 ARNTL 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ARNTL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MTA1 ARNTL 24089055 trascriptional regulation,stimulation inferred by curator TFlink
NR1D1 ARNTL 21881539 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E0AEA ARNTL 21799909 22958478 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000535FDD ARNTL 21799909 rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000535FDD ARNTL 21799909 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001E0AEA ARNTL 17612493 21799909 22958478 23592263 24928439 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 ARNTL 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000075D860 ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009262D ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 ARNTL 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 ARNTL 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE ARNTL 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 ARNTL 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F ARNTL 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B ARNTL 22135298 phosphorylation N/A PhosphoSite
NPAS2 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL NPAS2 25361965 interaction type N/A PTMCode2
CSNK1E ARNTL 25361965 interaction type N/A PTMCode2
ARNTL CSNK1E 25361965 interaction type N/A PTMCode2
ARNTL CRY2 25361965 interaction type N/A PTMCode2
CRY2 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL RXRA 25361965 interaction type N/A PTMCode2
RXRA ARNTL 25361965 interaction type N/A PTMCode2
PER2 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL PER2 25361965 interaction type N/A PTMCode2
CLOCK ARNTL 25361965 interaction type N/A PTMCode2
ARNTL CLOCK 25361965 interaction type N/A PTMCode2
EPAS1 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL EPAS1 25361965 interaction type N/A PTMCode2
PER3 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL PER3 25361965 interaction type N/A PTMCode2
SIRT1 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL SIRT1 25361965 interaction type N/A PTMCode2
PER1 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL PER1 25361965 interaction type N/A PTMCode2
CRY1 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL CRY1 25361965 interaction type N/A PTMCode2
DBP ARNTL 25361965 interaction type N/A PTMCode2
ARNTL DBP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I ARNTL 14525934 18644859 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
OIP5 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TFPT ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
BHLHE40 ARNTL 12397359 14525934 15193144 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
RARA ARNTL 25348397 N/A physical interaction ComPPI
JUN ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CREBBP ARNTL 24234451 24737000 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EP300 ARNTL 25348397 N/A physical interaction ComPPI
HIF1A ARNTL 14525934 25348397 9576906 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
KAT2B ARNTL 25348397 N/A physical interaction ComPPI
HSP90AA1 ARNTL 14525934 25348397 9079689 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CSNK1E ARNTL 11875063 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PPP1CA ARNTL 25348397 N/A physical interaction ComPPI
HMG20A ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DYRK1B ARNTL 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
GOLGA5 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RABGEF1 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AHR ARNTL 14525934 25348397 9079689 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
PER3 ARNTL 14525934 14701732 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SIRT1 ARNTL 25348397 N/A physical interaction ComPPI
GIT2 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GRIPAP1 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TUFT1 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL CLOCK 11018023 14525934 24234451 25348397 9989497 physical association two hybrid,experimental interaction detection,physical interaction,in vivo,inference by socio-affinity scoring ComPPI,HPRD,IntAct
ARNTL EPAS1 11018023 14525934 24234451 25348397 9576906 physical association two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
ARNTL CRY1 10531061 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ARNTL NPAS4 14525934 14701734 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ARNTL HLF 14525934 25348397 9704006 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
ARNTL NPAS2 11439184 14525934 25348397 9576906 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
ARNTL RXRA 25348397 N/A physical interaction ComPPI
ARNTL HSP90AA2P 25348397 N/A physical interaction ComPPI
ARNTL UBE3A 24728990 25348397 25660546 27898060 N/A physical interaction ComPPI,OmniPath
ARNTL CRY2 25348397 N/A physical interaction ComPPI
ARNTL CSNK2B 25348397 N/A physical interaction ComPPI
ARNTL DELEC1 25348397 N/A physical interaction ComPPI
ARNTL RORC 25348397 N/A physical interaction ComPPI
ARNTL RHOU 25348397 N/A physical interaction ComPPI
ARNTL ARNTL2 25348397 N/A physical interaction ComPPI
ARNTL MAX 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL RPRD1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL HAUS6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL PHLDB3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL CAVIN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL PHF21A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL CCDC93 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL VPS50 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL RCOR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL DZIP3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL VPS53 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL PSMD9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL RABGAP1L 25348397 N/A physical interaction ComPPI
ARNTL RABGAP1L 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL YEATS4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL CCHCR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL NCKAP5L 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL PKN3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL KDM1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL NUF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARNTL KCTD7 25348397 N/A physical interaction ComPPI
ARNTL VPS51 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
BCAM ARNTL 25348397 N/A physical interaction ComPPI
WDR5 ARNTL 25348397 N/A physical interaction ComPPI
THAP11 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LRFN4 ARNTL 25348397 N/A physical interaction ComPPI
HMGA1 ARNTL 24234451 30021884 physical association cross-linking study IntAct
PER1 ARNTL 14701732 16717091 18662546 21680841 21966515 27898060 inhibition N/A OmniPath
RORC ARNTL 18454201 23555304 27898060 stimulant N/A OmniPath
ARNTL CRY2 14701732 16717091 18662546 19106159 27898060 stimulant N/A OmniPath
CRY2 ARNTL 14701732 16717091 18662546 19106159 27898060 inhibition N/A OmniPath
NR1D1 ARNTL 18662546 20159955 25260595 27898060 inhibition N/A OmniPath
PER2 ARNTL 14701732 16717091 18662546 21113167 21680841 22274616 27898060 inhibition N/A OmniPath
NR1D2 ARNTL 18662546 27898060 inhibition N/A OmniPath
UBE2I ARNTL 18644859 27898060 N/A N/A OmniPath
RORB ARNTL 18454201 27898060 stimulant N/A OmniPath
ARNTL CRY1 10531061 14701732 15226430 16717091 18662546 19106159 21966515 23555304 25127877 25756610 27898060 stimulant N/A OmniPath
CRY1 ARNTL 10531061 14701732 15226430 16717091 18662546 19106159 21966515 23555304 25127877 25756610 27898060 inhibition N/A OmniPath
ARNTL HIF1A 25416956 27898060 9576906 9704006 N/A N/A OmniPath
GSK3B ARNTL 20049328 27898060 inhibition N/A OmniPath
PER3 ARNTL 14701732 18662546 27898060 inhibition N/A OmniPath
RORA ARNTL 18454201 18662546 27898060 inhibition,stimulant N/A OmniPath
ARNTL MAGEL2 22208286 27898060 inhibition N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AFC21 ARNTL 27087310 direct interaction,inhibition N/A NPInter

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