Gene Information gene info

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GENE：BHLHE40

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BHLHE40
FullNmae basic helix-loop-helix family member e40
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1046
EnsembleID ENSG00000134107
Uniprot O14503

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BHLHE40 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BHLHE40 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BHLHE40 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BHLHE40 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BHLHE40 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0000981,GO:0001227,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005737,GO:0006355,GO:0006357,GO:0007623,GO:0009952,GO:0016604,GO:0019904,GO:0032922,GO:0032922,GO:0042752,GO:0042803,GO:0043153,GO:0043425,GO:0043426,GO:0043433,GO:0045892,GO:0045892,GO:0046982,GO:0050767,GO:0061629,GO:0070888,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BHLHE40 hsa:8553 path:hsa04710 Circadian rhythm - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BHLHE40 AAMP 23180781 25416956 physical association two hybrid InnateDB
BHLHE40 AANAT 23180781 25416956 physical association two hybrid InnateDB
TLE5 BHLHE40 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR BHLHE40 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 BHLHE40 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 BHLHE40 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A BHLHE40 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
RELA BHLHE40 20018891 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C BHLHE40 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR BHLHE40 18971253 23220548 trascriptional regulation,stimulation inferred by curator TFlink
TP53 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 BHLHE40 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ARNT BHLHE40 12354771 trascriptional regulation,stimulation inferred by curator TFlink
ARNTL BHLHE40 19032342 trascriptional regulation,stimulation inferred by curator TFlink
CLOCK BHLHE40 14672706 19032342 trascriptional regulation,stimulation inferred by curator TFlink
HDAC2 BHLHE40 21317427 trascriptional regulation,stimulation inferred by curator TFlink
NR1H3 BHLHE40 19032342 trascriptional regulation,stimulation inferred by curator TFlink
TP63 BHLHE40 21317427 trascriptional regulation,stimulation inferred by curator TFlink
VHL BHLHE40 11278694 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 BHLHE40 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000031602A BHLHE40 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 BHLHE40 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C BHLHE40 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D BHLHE40 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B BHLHE40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB BHLHE40 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 BHLHE40 19536157 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000006B702 BHLHE40 19536157 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004818BD BHLHE40 19536157 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000036B845 BHLHE40 19536157 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000085F64 BHLHE40 19536157 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 BHLHE40 19536157 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002CEB74 BHLHE40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 BHLHE40 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B BHLHE40 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BYSL BHLHE40 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBPMS BHLHE40 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2I BHLHE40 11278694 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,yeast display,physical interaction ComPPI,IntAct
RHOXF2 BHLHE40 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP23-1 BHLHE40 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 RHOBTB3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 COX5B 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 PDE6G 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 CDPF1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 SMYD1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 NOC4L 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 TXNL4B 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 ARNTL 12397359 14525934 15193144 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
BHLHE40 STAT3 14525934 15223310 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
BHLHE40 VIM 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BHLHE40 SETDB1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BHLHE40 ZHX1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BHLHE40 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BHLHE40 CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BHLHE40 TOLLIP 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BHLHE40 MYOD1 25348397 N/A physical interaction ComPPI
BHLHE40 ELAVL1 25348397 N/A physical interaction ComPPI
BHLHE40 RXRA 24234451 25348397 29234281 colocalization,physical association anti bait coimmunoprecipitation,cross-linking study,physical interaction,confocal microscopy ComPPI,IntAct
BHLHE40 BHLHE41 14525934 15193144 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
BHLHE40 SIN3A 25348397 N/A physical interaction ComPPI
BHLHE40 HDAC1 22723347 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BHLHE40 TP53 17347673 22723347 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,imaging technique ComPPI,IntAct
BHLHE40 APH1A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BHLHE40 HIVEP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BHLHE40 FBLN1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BHLHE40 CALML3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BHLHE40 ENO1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BHLHE40 NUMBL 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BHLHE40 RBFOX1 25348397 N/A physical interaction ComPPI
BHLHE40 USP21 25348397 N/A physical interaction ComPPI
BHLHE40 USP17L11 25348397 N/A physical interaction ComPPI
BHLHE40 USP17L22 25348397 N/A physical interaction ComPPI
BHLHE40 USP17L20 25348397 N/A physical interaction ComPPI
BHLHE40 BTRC 25348397 N/A physical interaction ComPPI
BHLHE40 FBXW11 25348397 N/A physical interaction ComPPI
BHLHE40 AAMP 25348397 N/A physical interaction ComPPI
BHLHE40 AANAT 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 TLE5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 DAB1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 EHHADH 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 PRKAA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 SOX15 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 CCNK 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 STK19 25348397 N/A physical interaction ComPPI
BHLHE40 MAGED1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 TOB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 PLEKHB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 RBM23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 VAC14 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 RHOJ 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 TTC23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 NAA50 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 LARP4 25348397 N/A physical interaction ComPPI
BHLHE40 TCF3 25348397 N/A physical interaction ComPPI
BHLHE40 SMARCB1 25348397 N/A physical interaction ComPPI
BHLHE40 MDM2 17347673 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
BHLHE40 CSNK2A1 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 CSNK2B 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 CSNK2A2 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 NPAS2 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 FBXL15 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 EZH2 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 PPP2R1B 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 PPP2R1A 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 PPP1CC 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 PPP1CB 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 PPP1CA 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 RORC 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 PPP2R5E 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 PPP2CA 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 NONO 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 NFIL3 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 NR1D2 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 RORB 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 GMCL2 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BHLHE40 TENT5B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 KLHDC7B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 RAD54L2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 FAM83A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 ROR2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 ATXN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 PFDN5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 SMAP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 DVL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 MCRS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 PHF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 KRTAP19-7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 VENTX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 KRTAP19-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 KRTAP8-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 KRTAP19-5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 PRR20D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 KRTAP6-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 POU6F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 RBPMS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 KRTAP6-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 DAZAP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 TP53BP1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
PPP2R5D BHLHE40 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
BHLHE40 BHLHE40 12297495 14525934 23555304 24234451 25416956 physical association two hybrid,experimental interaction detection,two hybrid array HPRD,IntAct
BHLHE40 CEBPB 22610404 27898060 N/A N/A OmniPath

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