GENE:BHLHE41
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | BHLHE41 |
| FullNmae | basic helix-loop-helix family member e41 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16617 |
| EnsembleID | ENSG00000123095 |
| Uniprot | Q9C0J9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| BHLHE41 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| BHLHE41 | GO:0000122,GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0001227,GO:0001227,GO:0005515,GO:0005634,GO:0006357,GO:0009952,GO:0010832,GO:0010944,GO:0032922,GO:0042803,GO:0042826,GO:0043425,GO:0043425,GO:0043426,GO:0045892,GO:0046982,GO:0050767,GO:0061629,GO:0070888,GO:0070888,GO:1990837 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| BHLHE41 | hsa:79365 | path:hsa04710 | Circadian rhythm - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | BHLHE41 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA2 | BHLHE41 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | BHLHE41 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| YBX1 | BHLHE41 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | BHLHE41 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | BHLHE41 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | BHLHE41 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | BHLHE41 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | BHLHE41 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | BHLHE41 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | BHLHE41 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CLOCK | BHLHE41 | 14672706 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GLI1 | BHLHE41 | 24165159 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GLI2 | BHLHE41 | 24165159 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BHLHE40 | BHLHE41 | 14525934 15193144 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| MYOD1 | BHLHE41 | 12657651 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| HIF1A | BHLHE41 | 22801492 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CEBPB | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| NONO | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| GSK3B | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| CSNK1E | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| CSNK2A1 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2CB | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| MKNK2 | BHLHE41 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PPP2R5E | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| ATM | BHLHE41 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSNK2A2 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| SIRT1 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| CRY2 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| RORA | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| PER2 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| KLC3 | BHLHE41 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PPP2R1B | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| CLOCK | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| PSMA4 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| CRY1 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| FBXW11 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| MYH13 | BHLHE41 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSNK2B | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| CEBPA | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| RASD1 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| WDR5 | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| CDCA5 | BHLHE41 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RORC | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| POLK | BHLHE41 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RXRA | BHLHE41 | 25348397 | N/A | physical interaction | ComPPI |
| HDAC1 | BHLHE41 | 17487425 20821348 22355045 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| BHLHE41 | DELEC1 | 25348397 | N/A | physical interaction | ComPPI |
| BHLHE41 | LLGL2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BHLHE41 | VPS26A | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NCOR2 | BHLHE41 | 12897056 27898060 | stimulant | N/A | OmniPath |
| CTBP1 | BHLHE41 | 16287852 27898060 | stimulant | N/A | OmniPath |
