Gene Information gene info

  1. Home

GENE：SYK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SYK
FullNmae spleen associated tyrosine kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11491
EnsembleID ENSG00000165025
Uniprot P43405

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SYK pyroptosis 34473281 The ex vivo studies indicated that STING could induce pyroptosis via spleen tyrosine kinase (Syk), and Syk knockdown weakened such pyroptotic tumor cells death. retulator signature
SYK necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SYK lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
SYK lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
SYK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SYK autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SYK GO:0001525,GO:0001775,GO:0001784,GO:0001784,GO:0001945,GO:0002092,GO:0002223,GO:0002223,GO:0002250,GO:0002250,GO:0002281,GO:0002281,GO:0002283,GO:0002283,GO:0002366,GO:0002554,GO:0002862,GO:0004672,GO:0004672,GO:0004674,GO:0004713,GO:0004713,GO:0004713,GO:0004713,GO:0004713,GO:0004715,GO:0004715,GO:0004715,GO:0004715,GO:0005102,GO:0005102,GO:0005178,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0006468,GO:0006468,GO:0006606,GO:0007159,GO:0007169,GO:0007229,GO:0007229,GO:0009887,GO:0010543,GO:0010803,GO:0016170,GO:0016301,GO:0016301,GO:0018108,GO:0018108,GO:0018108,GO:0018108,GO:0019370,GO:0019722,GO:0019815,GO:0019901,GO:0019902,GO:0030154,GO:0030168,GO:0030183,GO:0030593,GO:0031234,GO:0031334,GO:0031623,GO:0032009,GO:0032481,GO:0032725,GO:0032733,GO:0032735,GO:0032752,GO:0032753,GO:0032755,GO:0032757,GO:0032760,GO:0032765,GO:0032928,GO:0032930,GO:0032991,GO:0033630,GO:0033630,GO:0035325,GO:0035556,GO:0035556,GO:0035556,GO:0035556,GO:0038063,GO:0038095,GO:0038096,GO:0038156,GO:0042101,GO:0042169,GO:0042492,GO:0042742,GO:0043274,GO:0043280,GO:0043303,GO:0043306,GO:0043313,GO:0043366,GO:0043410,GO:0045087,GO:0045087,GO:0045579,GO:0045579,GO:0045588,GO:0045780,GO:0046638,GO:0046641,GO:0048514,GO:0050731,GO:0050764,GO:0050850,GO:0050853,GO:0050853,GO:0050853,GO:0051090,GO:0051712,GO:0070372,GO:0071226,GO:0071396,GO:0071404,GO:0071639,GO:0090237,GO:0090330,GO:0090330,GO:0097110,GO:0120162,GO:1904263,GO:1990858

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SYK hsa:6850 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
SYK hsa:6850 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
SYK hsa:6850 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
SYK hsa:6850 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
SYK hsa:6850 path:hsa04611 Platelet activation - Homo sapiens (human)
SYK hsa:6850 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
SYK hsa:6850 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
SYK hsa:6850 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
SYK hsa:6850 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)
SYK hsa:6850 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
SYK hsa:6850 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
SYK hsa:6850 path:hsa05152 Tuberculosis - Homo sapiens (human)
SYK hsa:6850 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
SYK hsa:6850 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
SYK hsa:6850 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
SYK hsa:6850 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
SYK hsa:6850 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SYK CD36 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 23896411 26192618 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615 interaction type N/A ACSN
GRB2 SYK 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
KDR SYK 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
SHC1 SYK 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
VEGFA SYK 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
VEGFB SYK 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
SYK NCK1 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
SYK FYN 10358164 10477689 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23180781 23609447 26192618 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615 interaction type,physical association gst pull down ACSN,InnateDB
CD247 SYK 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 26192618 7523143 8344348 8478617 8551221 9603467 9625766 9738502 interaction type N/A ACSN
FCER1G SYK 12731048 15081523 15099567 20814939 23414611 2451784 26192618 7590867 9625766 9952373 interaction type N/A ACSN
CLEC2B SYK 11265639 12731048 12740575 15972651 17057721 20663776 20814939 21149606 23609447 26192618 interaction type N/A ACSN
KIR2DS2 SYK 11015446 12731048 20814939 23715743 24586048 26192618 9490415 9625766 9655483 interaction type N/A ACSN
FCAR SYK 12731048 15081523 15099567 20814939 23414611 2451784 26192618 7590867 9625766 9952373 interaction type N/A ACSN
HLA-E SYK 11015446 12731048 20814939 23715743 24586048 26192618 2731048 9486650 9625766 9655483 interaction type N/A ACSN
KLRC2 SYK 11015446 12731048 20814939 23715743 24586048 26192618 2731048 9486650 9625766 9655483 interaction type N/A ACSN
KLRD1 SYK 11015446 12731048 20814939 23715743 24586048 26192618 2731048 9486650 9625766 9655483 interaction type N/A ACSN
SYK LAT 10358164 10426994 11907067 12524384 12731048 15536084 16713974 19909365 20814939 21149606 21378271 21910624 23609447 26192618 8189062 8226994 9000133 9314552 9396765 9632805 interaction type N/A ACSN
SYK TLR4 14699155 17228323 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYD88 SYK 17228323 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF6 SYK 11418661 23180781 physical association anti tag coimmunoprecipitation InnateDB
PIK3R1 SYK 11907067 12869549 15536084 16921024 23180781 29145629 physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
LCP2 SYK 15388330 23180781 phosphorylation reaction anti tag coimmunoprecipitation InnateDB
CLEC1B SYK 16174766 23180781 physical association gst pull down InnateDB
CBL SYK 10617633 11331248 23180781 physical association anti tag coimmunoprecipitation InnateDB
SYK SYK 10438543 10617633 10648173 16849466 18006696 18052078 18818202 21469132 23180781 29145629 7513017 7538118 8163536 8809042 9351824 phosphorylation reaction,enzymatic reaction,physical association inferred by curator,in-gel kinase assay,protein kinase assay InnateDB,Reactome
PLCG2 SYK 10026222 10469124 12573241 14656219 15161916 15184383 16449524 19592646 21659545 22041900 23180781 24243840 29145629 7517665 7518558 8629002 8630736 8657103 8702662 8986718 8995445 enzymatic reaction,physical association anti tag coimmunoprecipitation,gst pull down,inferred by curator InnateDB,Reactome
CTTN SYK 10438543 11389697 23180781 8636079 physical association anti tag coimmunoprecipitation InnateDB
SLC9A3R1 SYK 15467753 23180781 physical association anti tag coimmunoprecipitation,two hybrid,gst pull down InnateDB
SYK FCGR2A 15136586 23180781 8663460 9268059 phosphorylation reaction,physical association anti tag coimmunoprecipitation,gst pull down,protein kinase assay InnateDB
SYK FCGR1A 10477689 15136586 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
SYK FCER1G 23180781 8663460 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
CD3G SYK 11493682 23180781 physical association anti tag coimmunoprecipitation InnateDB
VAV1 SYK 11331248 12573241 16546099 23180781 23331499 24243840 29145629 7518558 8629002 8630736 8809042 8986718 phosphorylation reaction,enzymatic reaction,stimulation,physical association anti tag coimmunoprecipitation,gst pull down,inferred by curator,protein kinase assay InnateDB,Reactome,SignaLink
SYK LYN 10477689 23180781 7831290 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
GP1BA SYK 10477689 23180781 physical association gst pull down InnateDB
SYK CD247 23180781 7522230 physical association anti tag coimmunoprecipitation InnateDB
PAK2 SYK 14673144 23180781 physical association anti tag coimmunoprecipitation InnateDB
CEACAM3 SYK 17506820 23180781 physical association anti tag coimmunoprecipitation InnateDB
CD33 SYK 12763134 17947393 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
PTPN6 SYK 12763134 23180781 physical association anti tag coimmunoprecipitation InnateDB
CD22 SYK 23180781 8627166 physical association anti tag coimmunoprecipitation InnateDB
PLCG1 SYK 10026222 12573241 15161916 15184383 19592646 21659545 23180781 24243840 29145629 7517665 7518558 8627166 8629002 8630736 8657103 8702662 8986718 8995445 enzymatic reaction,physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
SELPLG SYK 12387735 23180781 physical association pull down InnateDB
IGKC SYK 10579907 10648173 16849466 18006696 18052078 18818202 21469132 24243840 29145629 7522622 7528327 7530449 7538118 7592958 8071371 8163536 8226994 8340414 8809042 8862523 8910399 9314552 enzymatic reaction,physical association inferred by curator Reactome
CD79A SYK 10648173 16849466 18006696 18052078 18818202 21469132 29145629 7538118 7592958 8163536 enzymatic reaction,physical association inferred by curator Reactome
IGHD SYK 10648173 16849466 18006696 18052078 18818202 21469132 29145629 7538118 7592958 8163536 enzymatic reaction,physical association inferred by curator Reactome
IGHM SYK 10648173 16849466 18006696 18052078 18818202 21469132 29145629 7538118 7592958 8163536 enzymatic reaction,physical association inferred by curator Reactome
CD79B SYK 10648173 16849466 18006696 18052078 18818202 21469132 29145629 7538118 7592958 8163536 enzymatic reaction,physical association inferred by curator Reactome
SYK SOS1 10026222 11071869 11449366 11909947 12456653 12573241 15184383 19372136 19592646 21659545 21822214 24243840 29145629 7518558 8629002 8630736 8702662 8986718 8995445 9341187 9697839 9705962 enzymatic reaction,physical association inferred by curator Reactome
SYK SH3KBP1 11071869 11449366 11909947 12456653 19372136 21822214 29145629 9341187 9697839 9705962 physical association inferred by curator Reactome
SYK BLNK 11071869 11449366 11909947 12456653 19372136 21822214 29145629 9341187 9697839 9705962 physical association inferred by curator Reactome
LYN SYK 11481033 1874735 19409513 24243840 29145629 7528327 8071371 8910399 physical association inferred by curator Reactome
FYN SYK 11481033 11907067 15536084 18691974 1874735 19409513 24243840 29145629 9396765 9490415 9830044 physical association inferred by curator Reactome
JAK1 SYK 10825200 29145629 7600304 physical association inferred by curator Reactome
SYK BTK 12573241 15184383 21659545 24243840 29145629 7518558 8629002 8630736 8986718 enzymatic reaction inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
BLNK SYK 10981967 18988627 20005715 interaction type N/A PSP,SignaLink
CD19 SYK 20005715 interaction type N/A PSP,SignaLink
DBNL SYK 20005715 interaction type N/A PSP
GRB2 SYK 20005715 interaction type N/A PSP,SignaLink
LAT SYK 20005715 interaction type N/A PSP
LAX1 SYK 20005715 interaction type N/A PSP,SignaLink
LCP2 SYK 20005715 interaction type N/A PSP
PAG1 SYK 20005715 interaction type N/A PSP
PIK3R1 SYK 20005715 interaction type N/A PSP
PXN SYK 20005715 interaction type N/A PSP
SH2B2 SYK 10872802 18988627 20005715 interaction type N/A PSP,SignaLink
SH3BP2 SYK 20005715 interaction type N/A PSP
SHC1 SYK 20005715 interaction type N/A PSP
SIT1 SYK 20005715 interaction type N/A PSP
SNCA SYK 20005715 interaction type N/A PSP
TYROBP SYK 20005715 interaction type N/A PSP,SignaLink
PAG1 SYK 10790433 10790433 18988627 20005715 20005715 21071413 N/A N/A SignaLink
LCP2 SYK 15388330 18988627 20005715 20005715 N/A N/A SignaLink
PIK3R1 SYK 15536084 18988627 20005715 20005715 N/A N/A SignaLink
SHC1 SYK 20005715 20005715 N/A N/A SignaLink
DBNL SYK 20005715 20005715 N/A N/A SignaLink
LAT SYK 11368773 18988627 20005715 20005715 21071413 9891970 N/A N/A SignaLink
PXN SYK 20005715 20005715 21071413 9590268 N/A N/A SignaLink
SH3BP2 SYK 20005715 20005715 21071413 9846481 N/A N/A SignaLink
SIT1 SYK 10209036 18988627 20005715 20005715 N/A N/A SignaLink
SNCA SYK 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 SYK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SYK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN SYK 22354960 trascriptional regulation,stimulation inferred by curator TFlink
MYC SYK N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C308D SYK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 SYK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC SYK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003E2232 SYK 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED SYK 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 SYK 19536157 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 SYK 19536157 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 SYK 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 SYK 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 SYK 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED SYK 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 SYK 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA SYK 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FAA8C SYK 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB SYK 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 SYK 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 SYK 25416803 25983556 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 SYK 22135298 phosphorylation N/A PhosphoSite
SYK SLC4A1 22135298 phosphorylation N/A PhosphoSite
SYK FCGR2C 22135298 phosphorylation N/A PhosphoSite
SYK PLCG1 22135298 phosphorylation N/A PhosphoSite
SYK BLNK 22135298 phosphorylation N/A PhosphoSite
SYK PLCG2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK HCLS1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK FCGR2A 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK IKZF1 22135298 phosphorylation N/A PhosphoSite
SYK CFTR 22135298 phosphorylation N/A PhosphoSite
SYK LAT2 22135298 phosphorylation N/A PhosphoSite
SYK ARHGDIB 22135298 phosphorylation N/A PhosphoSite
SYK STAT5A 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK CBL 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK SNCA 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK DUSP3 22135298 phosphorylation N/A PhosphoSite
SYK SYK 22135298 phosphorylation N/A PhosphoSite
SYK BTK 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK GCSAM 22135298 phosphorylation N/A PhosphoSite
SYK MAPT 22135298 phosphorylation N/A PhosphoSite
SYK LCP2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SYK PIP5K1B 22135298 phosphorylation N/A PhosphoSite
CHEK1 SYK 22135298 phosphorylation N/A PhosphoSite
MSN SYK 25361965 interaction type N/A PTMCode2
SYK MSN 25361965 interaction type N/A PTMCode2
STAT3 SYK 25361965 interaction type N/A PTMCode2
SYK STAT3 25361965 interaction type N/A PTMCode2
CBLB SYK 25361965 interaction type N/A PTMCode2
SYK CBLB 25361965 interaction type N/A PTMCode2
SNCA SYK 25361965 interaction type N/A PTMCode2
PLCG2 SYK 25361965 interaction type N/A PTMCode2
LCK SYK 25361965 interaction type N/A PTMCode2
SYK LCK 25361965 interaction type N/A PTMCode2
LAX1 SYK 25361965 interaction type N/A PTMCode2
SYK LAX1 25361965 interaction type N/A PTMCode2
PTK2B SYK 25361965 interaction type N/A PTMCode2
SYK PTK2B 25361965 interaction type N/A PTMCode2
CD4 SYK 25361965 interaction type N/A PTMCode2
SYK CD4 25361965 interaction type N/A PTMCode2
CD3E SYK 25361965 interaction type N/A PTMCode2
SYK CD3E 25361965 interaction type N/A PTMCode2
CBL SYK 25361965 interaction type N/A PTMCode2
CSF3R SYK 25361965 interaction type N/A PTMCode2
SYK CSF3R 25361965 interaction type N/A PTMCode2
CD72 SYK 25361965 interaction type N/A PTMCode2
SYK CD72 25361965 interaction type N/A PTMCode2
FYN SYK 25361965 interaction type N/A PTMCode2
SYK FYN 25361965 interaction type N/A PTMCode2
ITGB2 SYK 25361965 interaction type N/A PTMCode2
SYK ITGB2 25361965 interaction type N/A PTMCode2
STAT5A SYK 25361965 interaction type N/A PTMCode2
SIRPB1 SYK 25361965 interaction type N/A PTMCode2
SYK SIRPB1 25361965 interaction type N/A PTMCode2
FCER1G SYK 25361965 interaction type N/A PTMCode2
SYK FCER1G 25361965 interaction type N/A PTMCode2
HCLS1 SYK 25361965 interaction type N/A PTMCode2
JAK1 SYK 25361965 interaction type N/A PTMCode2
SYK JAK1 25361965 interaction type N/A PTMCode2
LCP2 SYK 25361965 interaction type N/A PTMCode2
NFAM1 SYK 25361965 interaction type N/A PTMCode2
SYK NFAM1 25361965 interaction type N/A PTMCode2
EPOR SYK 25361965 interaction type N/A PTMCode2
SYK EPOR 25361965 interaction type N/A PTMCode2
SRC SYK 25361965 interaction type N/A PTMCode2
SYK SRC 25361965 interaction type N/A PTMCode2
CTTN SYK 25361965 interaction type N/A PTMCode2
SYK CTTN 25361965 interaction type N/A PTMCode2
FCGR2A SYK 25361965 interaction type N/A PTMCode2
SYK PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SYK 25361965 interaction type N/A PTMCode2
SYK SHC1 25361965 interaction type N/A PTMCode2
SHC1 SYK 25361965 interaction type N/A PTMCode2
SYK DBNL 25361965 interaction type N/A PTMCode2
DBNL SYK 25361965 interaction type N/A PTMCode2
GRB2 SYK 25361965 interaction type N/A PTMCode2
SYK GRB2 25361965 interaction type N/A PTMCode2
VAV2 SYK 25361965 interaction type N/A PTMCode2
SYK VAV2 25361965 interaction type N/A PTMCode2
PRKD1 SYK 25361965 interaction type N/A PTMCode2
SYK PRKD1 25361965 interaction type N/A PTMCode2
PAG1 SYK 25361965 interaction type N/A PTMCode2
SYK PAG1 25361965 interaction type N/A PTMCode2
TRAF6 SYK 25361965 interaction type N/A PTMCode2
SYK TRAF6 25361965 interaction type N/A PTMCode2
CRKL SYK 25361965 interaction type N/A PTMCode2
SYK CRKL 25361965 interaction type N/A PTMCode2
CD22 SYK 25361965 interaction type N/A PTMCode2
SYK CD22 25361965 interaction type N/A PTMCode2
PIK3R1 SYK 25361965 interaction type N/A PTMCode2
SYK PIK3R1 25361965 interaction type N/A PTMCode2
GAB2 SYK 25361965 interaction type N/A PTMCode2
SYK GAB2 25361965 interaction type N/A PTMCode2
SIT1 SYK 25361965 interaction type N/A PTMCode2
SYK SIT1 25361965 interaction type N/A PTMCode2
TYROBP SYK 25361965 interaction type N/A PTMCode2
SYK TYROBP 25361965 interaction type N/A PTMCode2
FGR SYK 25361965 interaction type N/A PTMCode2
SYK FGR 25361965 interaction type N/A PTMCode2
IL2RB SYK 25361965 interaction type N/A PTMCode2
SYK IL2RB 25361965 interaction type N/A PTMCode2
BTK SYK 25361965 interaction type N/A PTMCode2
CD79A SYK 25361965 interaction type N/A PTMCode2
SYK CD79A 25361965 interaction type N/A PTMCode2
PIK3R2 SYK 25361965 interaction type N/A PTMCode2
SYK PIK3R2 25361965 interaction type N/A PTMCode2
POU2AF1 SYK 25361965 interaction type N/A PTMCode2
SYK POU2AF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIK3R2 SYK 14525934 15536084 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LCP2 SYK 14525934 15388330 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SEC23B SYK 25348397 N/A physical interaction ComPPI
UBASH3B SYK 20585042 22267732 24234451 25348397 27898060 dephosphorylation reaction,physical association pull down,physical interaction,phosphatase assay ComPPI,IntAct,OmniPath
LAT SYK 14525934 25348397 9891970 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
STAT1 SYK 14525934 15467722 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TUBB SYK 25348397 N/A physical interaction ComPPI
TRAF6 SYK 11418661 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CALM1 SYK 25348397 N/A physical interaction ComPPI
PTPN6 SYK 10072516 11356834 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ERBB2 SYK 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
CD4 SYK 25348397 N/A physical interaction ComPPI
CBL SYK 10540342 11133830 14525934 15556646 18273061 24234451 25348397 8621719 9857068 phosphorylation reaction,physical association coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
VAV1 SYK 14525934 25348397 8986718 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
BTK SYK 11226282 11598012 14525934 25348397 8629002 8630736 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK LYN 11536198 14525934 25348397 7831290 8621719 9820500 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK PRKCA 12881490 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK GRB2 11964172 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK SRC 14525934 25348397 7513017 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK TUBA4A 14525934 25348397 8617742 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK SLC4A1 10942405 14525934 16118313 1998697 2065070 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK SHC1 10482988 14525934 25348397 9096689 9388490 9710204 N/A experimental interaction detection,in vivo ComPPI,HPRD
SYK SLA 10449770 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK PTK2B 10747947 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK HCLS1 14525934 24234451 25241761 25348397 9104825 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
SYK STAT5A 10825200 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SYK MAP4K1 11514608 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK CRKL 11313252 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK SH3BP2 11390470 12709437 14525934 15345594 24234451 25348397 9846481 association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SYK PXN 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SYK TUBA1A 10862713 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SYK HNRNPU 14525934 25348397 7831290 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK TYROBP 10940905 14525934 24234451 25348397 9490415 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SYK BLNK 10981967 14525934 18369315 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
SYK SIT1 10209036 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK PAG1 10790433 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SYK GAB2 11895767 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK CD3E 14525934 24234451 25348397 7761456 9698567 association experimental interaction detection,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
SYK SH2B2 10872802 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SYK NFAM1 14525934 15143214 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK DBNL 14525934 25348397 9891087 N/A experimental interaction detection,in vivo ComPPI,HPRD
SYK CD79A 14525934 25348397 7500027 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK STAT3 10825200 14525934 20133729 21516116 24234451 25348397 25416956 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
SYK SELPLG 12387735 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK IL15RA 11714793 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK CSF2RB 14525934 25348397 8666899 N/A experimental interaction detection,in vivo ComPPI,HPRD
SYK RASA1 14525934 25348397 9218456 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK IL2RB 14525934 25348397 7600304 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK CD79B 12453414 14525934 25348397 7538118 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK PLCG2 25348397 N/A physical interaction,in vitro ComPPI
SYK VAV2 14525934 15345594 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
SYK RPS6KA1 14525934 25348397 9218456 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK MAPK3 14525934 25348397 9218456 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK TLR4 14525934 14699155 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK CBLB 10022120 12771181 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SYK PRKD1 14525934 25348397 8885868 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK PIK3AP1 11163197 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK LAX1 12359715 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SYK PIK3R1 14525934 15536084 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
SYK DUSP3 12447358 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SYK TNFRSF1A 14525934 16291755 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK POU2AF1 14525934 16713566 24234451 25348397 27898060 colocalization experimental interaction detection,fluorescence microscopy,in vivo ComPPI,HPRD,IntAct,OmniPath
SYK EPOR 14525934 25348397 9852052 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK FYN 14525934 25348397 9535867 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK CSF3R 14525934 25348397 8197119 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SYK FCGR1A 11141335 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
SYK FCGR2A 14525934 24234451 25348397 7487883 8756631 9280292 9295288 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SYK MS4A2 14525934 25348397 8071371 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SYK FCER1G 14525934 24234451 25348397 8071371 8810294 9280292 association,physical association experimental interaction detection,pull down,physical interaction,kinase scintillation proximity assay,in vitro,in vivo ComPPI,HPRD,IntAct
SYK JAK1 10825200 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SYK LCK 14525934 15536084 24234451 25348397 7539035 8621719 8798676 8798764 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
SYK SNCA 11162638 11744621 12096713 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SYK CD19 14525934 25348397 9120258 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYK CD22 14525934 24234451 25348397 8627166 8647200 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
SYK CTTN 14525934 24234451 25241761 25348397 8636079 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
SYK PLCG1 14525934 15144186 1689310 24234451 25348397 7682059 8657103 8885868 association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
SYK RPS6KB1 25348397 N/A physical interaction ComPPI
SYK RPS6KB2 25348397 N/A physical interaction ComPPI
SYK CD72 25348397 N/A physical interaction ComPPI
SYK PTK2 25348397 N/A physical interaction ComPPI
SYK FGR 11672534 14525934 15536084 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
SYK SIRPB1 10940905 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SYK FCRL3 25348397 N/A physical interaction ComPPI
SYK HDAC1 25348397 N/A physical interaction ComPPI
SYK HDAC3 25348397 N/A physical interaction ComPPI
SYK HDAC6 25348397 N/A physical interaction ComPPI
SYK HDAC9 25348397 N/A physical interaction ComPPI
SYK HDAC2 25348397 N/A physical interaction ComPPI
SYK HDAC4 25348397 N/A physical interaction ComPPI
SYK SP1 25348397 N/A physical interaction ComPPI
SYK TUBG1 16322234 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SYK NEDD4 25348397 N/A physical interaction ComPPI
SYK USP25 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SYK INPP5D 25348397 N/A physical interaction ComPPI
SYK NCK1 25348397 N/A physical interaction ComPPI
SYK GRAP2 25348397 N/A physical interaction ComPPI
SYK ITGB3 25348397 N/A physical interaction ComPPI
SYK RPS10 25348397 N/A physical interaction ComPPI
SYK FCER1A 25348397 N/A physical interaction ComPPI
SYK TERF1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
SYK PIK3CG 25348397 N/A physical interaction ComPPI
SYK MAPT 25348397 N/A physical interaction ComPPI
SYK APP 25348397 N/A physical interaction ComPPI
SYK VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
SYK EGFR 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SYK ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SYK ERBB4 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SYK ITGA4 25348397 N/A physical interaction ComPPI
SYK TLR3 25348397 N/A physical interaction ComPPI
SYK TLR9 25348397 N/A physical interaction ComPPI
SYK TRAF3 25348397 N/A physical interaction ComPPI
SYK TBK1 25348397 N/A physical interaction ComPPI
SYK MYD88 25348397 N/A physical interaction ComPPI
SYK MAP3K7 25348397 N/A physical interaction ComPPI
SYK TICAM1 25348397 N/A physical interaction ComPPI
SYK FCGR3A 25348397 N/A physical interaction ComPPI
SYK PTPRO 25348397 N/A physical interaction ComPPI
SYK IL17RA 25348397 N/A physical interaction ComPPI
SYK TRAF3IP2 25348397 N/A physical interaction ComPPI
SYK SH2D2A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SYK PEAR1 25348397 N/A physical interaction ComPPI
SYK MEGF10 25348397 N/A physical interaction ComPPI
SYK TENT5A 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping,validated two hybrid ComPPI,IntAct
SYK TRIM15 25348397 N/A physical interaction ComPPI
SYK RHOU 25348397 N/A physical interaction ComPPI
SYK HGS 25348397 N/A physical interaction ComPPI
SYK GRM1 25348397 N/A physical interaction ComPPI
SYK TAMALIN 25348397 N/A physical interaction ComPPI
SYK FLNA 25348397 N/A physical interaction ComPPI
SYK DPP9 25348397 N/A physical interaction ComPPI
SYK RPS6KA2 25348397 N/A physical interaction,biochemical ComPPI
SYK MSN 12387735 24234451 25348397 association pull down ComPPI,IntAct
SYK CD37 22624718 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
SYK MAL 22366891 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SYK FLT3 24234451 24525236 25348397 27898060 28086240 phosphorylation reaction,colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,protein array,protein kinase assay,confocal microscopy ComPPI,IntAct,OmniPath
SYK AR 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SYK KIT 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SYK MET 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SYK HAVCR2 24234451 25348397 26492563 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
SYK NLRP3 24234451 25348397 25605870 physical association anti tag coimmunoprecipitation ComPPI,IntAct
SYK CASP1 24234451 25348397 25605870 association anti tag coimmunoprecipitation ComPPI,IntAct
SYK PYCARD 24234451 25348397 25605870 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,protein kinase assay ComPPI,IntAct
GAB1 SYK 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
ITGB2 SYK 12885943 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
PKM SYK 25348397 N/A protein kinase assay ComPPI
TRAIP SYK 19151749 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SYK SYK 11356834 14525934 24234451 25605870 8657103 9698567 9820500 9857068 phosphorylation reaction experimental interaction detection,protein kinase assay HPRD,IntAct
SYK UBB 11046148 14525934 N/A experimental interaction detection HPRD
CEACAM3 SYK 17506820 27898060 N/A N/A OmniPath
SRC SYK 27898060 7513017 9389695 stimulant N/A OmniPath
SYK PLCG1 12601080 15144186 15592455 16038803 16126727 16497976 1689310 17016520 17081983 1708307 17389395 19534553 19690332 20068231 27898060 7682059 7744830 7831290 7991458 8627166 8657103 8885868 stimulant N/A OmniPath
SYK LCK 15536084 16497976 19664994 27898060 7539035 8621719 8798676 8798764 inhibition N/A OmniPath
SYK PRKCA 12881490 20068231 27898060 stimulant N/A OmniPath
LYN SYK 10477689 11536198 17389395 18083107 19369195 21469132 27898060 7831290 8621719 9820500 stimulant N/A OmniPath
SYK LYN 10477689 11536198 27898060 7831290 8621719 9820500 N/A N/A OmniPath
CHEK1 SYK 22585575 27898060 inhibition N/A OmniPath
SYK HCLS1 16782030 18587398 25241761 27898060 8578591 9104825 stimulant N/A OmniPath
SYK STAT6 10961885 15069079 15523052 27898060 N/A N/A OmniPath
SYK CD28 27898060 8946678 N/A N/A OmniPath
SYK IL7R 27898060 7719938 N/A N/A OmniPath
SYK TRAF6 11418661 23962979 25202827 27898060 N/A N/A OmniPath
TRAF6 SYK 11418661 23962979 25202827 27898060 N/A N/A OmniPath
TLR4 SYK 14699155 17228323 27898060 N/A N/A OmniPath
MYD88 SYK 17228323 27898060 N/A N/A OmniPath
PTPN6 SYK 10072516 10458769 10747947 11356834 12763134 27898060 inhibition N/A OmniPath
SYK BTK 11226282 11598012 18083107 19369195 27898060 8629002 8630736 9012831 stimulant N/A OmniPath
SYK SHC1 10482988 10598576 10891441 11075717 11687594 12237775 15688026 16251354 16477370 16497976 17016520 17389395 19901323 20068231 24552815 27898060 9096689 9121430 9388490 9685404 9710204 9741627 9813159 stimulant N/A OmniPath
PIK3R1 SYK 15536084 16921024 27898060 N/A N/A OmniPath
SYK PIK3R1 15536084 16921024 27898060 stimulant N/A OmniPath
SYK TYROBP 10940905 27898060 9490415 N/A N/A OmniPath
CBL SYK 10540342 10570266 10617633 11042121 11133830 11331248 11742985 12435267 15536084 15556646 15577829 15737992 16289966 18273061 27898060 7721825 8621719 9857068 inhibition N/A OmniPath
SYK CBL 10540342 10570266 10617633 10635327 10829062 11042121 11133830 11331248 11742985 12435267 15117950 15536084 15556646 15577829 15737992 15922744 16289966 18273061 27898060 7721825 8621719 9102067 9525940 9857068 N/A N/A OmniPath
SYK MAPT 18070606 27898060 inhibition N/A OmniPath
SYK PAK2 14673144 27898060 N/A N/A OmniPath
SYK IL4R 10358772 27898060 9545332 9670964 9697832 9712048 N/A N/A OmniPath
SYK SNCA 10617630 11078745 11162638 11744621 11813001 12096713 27898060 inhibition,stimulant N/A OmniPath
SYK MAPK8 15755722 27898060 N/A N/A OmniPath
SYK ICAM1 14973144 27898060 N/A N/A OmniPath
SYK FCGR2A 11141335 15136586 27898060 7487883 8663460 8756631 9268059 9280292 9295288 N/A N/A OmniPath
SYK MPL 27898060 9122198 N/A N/A OmniPath
SYK LCP2 15388330 15714472 22267732 27898060 stimulant N/A OmniPath
SYK CAV2 12743374 15504032 27898060 N/A N/A OmniPath
SYK IL15RA 11714793 27898060 stimulant N/A OmniPath
VAV1 SYK 11262396 11331248 27898060 8900182 8986718 stimulant N/A OmniPath
SYK VAV1 11262396 11331248 27898060 8900182 8986718 stimulant N/A OmniPath
SYK CFTR 21807898 27898060 N/A N/A OmniPath
SYK TUBA4A 27898060 8617742 9490415 stimulant N/A OmniPath
SYK PFKFB2 12853467 27898060 N/A N/A OmniPath
SYK PTK2B 10747947 27898060 8816475 stimulant N/A OmniPath
SYK TUBA1A 10862713 27898060 8617742 stimulant N/A OmniPath
SYK LAT2 14722116 17993265 27898060 stimulant N/A OmniPath
SYK ATP2B4 12540962 27898060 9182531 N/A N/A OmniPath
SYK MAP4K1 11514608 27898060 stimulant N/A OmniPath
SYK DUSP3 12447358 27898060 stimulant N/A OmniPath
SYK SDC3 27898060 9388509 N/A N/A OmniPath
SYK ITGB3 27898060 8631894 stimulant N/A OmniPath
SYK VAMP4 14608369 27898060 N/A N/A OmniPath
SYK PIP5K1B 19553680 27898060 N/A N/A OmniPath
SYK SH3BP2 11390470 12709437 20439986 27898060 9846481 stimulant N/A OmniPath
SYK ADCY3 27898060 8798667 9768837 N/A N/A OmniPath
SYK IKZF1 23071339 27898060 stimulant N/A OmniPath
SYK SLC4A1 10942405 16118313 1998697 2065070 27898060 6681814 stimulant N/A OmniPath
SYK ARHGDIB 19321744 24055812 27898060 N/A N/A OmniPath
SYK BLNK 10981967 12456653 18369315 21394647 21482705 21822214 27898060 9697839 stimulant N/A OmniPath
SYK GCSAM 17489982 17823310 27898060 N/A N/A OmniPath
SYK DOK2 10508618 11689432 27898060 9764820 N/A N/A OmniPath
SYK P2RY4 11114308 27898060 N/A N/A OmniPath
SYK FCGR2C 27898060 8756631 N/A N/A OmniPath

Visualization










  Return