Gene Information gene info

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GENE：CRY1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CRY1
FullNmae cryptochrome circadian regulator 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2384
EnsembleID ENSG00000008405
Uniprot Q16526

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CRY1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CRY1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CRY1 GO:0000122,GO:0003677,GO:0003690,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005737,GO:0005739,GO:0006094,GO:0007623,GO:0009416,GO:0009785,GO:0009882,GO:0014823,GO:0016922,GO:0019901,GO:0019902,GO:0019915,GO:0031397,GO:0031398,GO:0032868,GO:0032922,GO:0032922,GO:0033762,GO:0042593,GO:0042752,GO:0042754,GO:0042770,GO:0042826,GO:0043153,GO:0043153,GO:0045721,GO:0045722,GO:0045744,GO:0045892,GO:0045892,GO:0045892,GO:0061912,GO:0070888,GO:0071949,GO:2000001,GO:2000323,GO:2000850

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CRY1 hsa:1407 path:hsa04710 Circadian rhythm - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 CRY1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 CRY1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 CRY1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CRY1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CRY1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CRY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ARNTL CRY1 17660446 22750052 trascriptional regulation,stimulation inferred by curator TFlink
CLOCK CRY1 17660446 22750052 trascriptional regulation,stimulation inferred by curator TFlink
NPAS2 CRY1 17660446 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000005481D CRY1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CRY1 PER2 25361965 interaction type N/A PTMCode2
PER2 CRY1 25361965 interaction type N/A PTMCode2
CRY1 PER1 25361965 interaction type N/A PTMCode2
PER1 CRY1 25361965 interaction type N/A PTMCode2
CRY1 NPAS2 25361965 interaction type N/A PTMCode2
NPAS2 CRY1 25361965 interaction type N/A PTMCode2
CRY1 CSNK1E 25361965 interaction type N/A PTMCode2
CSNK1E CRY1 25361965 interaction type N/A PTMCode2
CRY1 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL CRY1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TEKT4 CRY1 25348397 N/A physical interaction ComPPI
HNRNPK CRY1 25348397 N/A physical interaction ComPPI
KRTAP4-12 CRY1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KRT2 CRY1 25348397 N/A physical interaction ComPPI
NPM1 CRY1 25348397 N/A physical interaction ComPPI
PCBP1 CRY1 25348397 N/A physical interaction ComPPI
IMPDH2 CRY1 25348397 N/A physical interaction ComPPI
PSMC6 CRY1 25348397 N/A physical interaction ComPPI
PPP2R1A CRY1 25348397 N/A physical interaction ComPPI
TUBB CRY1 25348397 N/A physical interaction ComPPI
QPRT CRY1 25348397 N/A physical interaction ComPPI
SKP1 CRY1 25348397 N/A physical interaction ComPPI
HNRNPH2 CRY1 25348397 N/A physical interaction ComPPI
CSNK1D CRY1 25348397 N/A physical interaction ComPPI
MDFI CRY1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CBLB CRY1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RPL10 CRY1 25348397 N/A physical interaction ComPPI
PRKDC CRY1 25348397 N/A physical interaction ComPPI
KHDRBS1 CRY1 25348397 N/A physical interaction ComPPI
USP7 CRY1 25348397 N/A physical interaction ComPPI
SFPQ CRY1 25348397 N/A physical interaction ComPPI
FLNA CRY1 25348397 N/A physical interaction ComPPI
PSMD11 CRY1 25348397 N/A physical interaction ComPPI
GRN CRY1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PLSCR1 CRY1 14525934 16189514 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KPNB1 CRY1 25348397 N/A physical interaction ComPPI
YWHAB CRY1 25348397 N/A physical interaction ComPPI
SCYL2 CRY1 25348397 N/A physical interaction ComPPI
YWHAZ CRY1 25348397 N/A physical interaction ComPPI
UBB CRY1 25348397 N/A physical interaction ComPPI
RPS27A CRY1 25348397 N/A physical interaction ComPPI
BTRC CRY1 25348397 N/A physical interaction ComPPI
RUVBL1 CRY1 25348397 N/A physical interaction ComPPI
BAG6 CRY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XRCC5 CRY1 25348397 N/A physical interaction ComPPI
CSNK1E CRY1 11875063 14525934 23455922 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
HSPA5 CRY1 25348397 N/A physical interaction ComPPI
HSPA1A CRY1 25348397 N/A physical interaction ComPPI
HSPA1B CRY1 25348397 N/A physical interaction ComPPI
PRDX4 CRY1 25348397 N/A physical interaction ComPPI
PRDX1 CRY1 25348397 N/A physical interaction ComPPI
HNRNPU CRY1 25348397 N/A physical interaction ComPPI
PABPC4 CRY1 25348397 N/A physical interaction ComPPI
PPP2CB CRY1 25348397 N/A physical interaction ComPPI
TXN CRY1 25348397 N/A physical interaction ComPPI
EEF1A1 CRY1 25348397 N/A physical interaction ComPPI
PRMT5 CRY1 25348397 N/A physical interaction ComPPI
HNRNPL CRY1 25348397 N/A physical interaction ComPPI
C1QBP CRY1 25348397 N/A physical interaction ComPPI
PABPC1 CRY1 25348397 N/A physical interaction ComPPI
PPP2R5E CRY1 25348397 N/A physical interaction ComPPI
PKM CRY1 25348397 N/A physical interaction ComPPI
EPRS1 CRY1 25348397 N/A physical interaction ComPPI
RARS1 CRY1 25348397 N/A physical interaction ComPPI
LTBP4 CRY1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
XPO1 CRY1 25348397 N/A physical interaction ComPPI
YWHAQ CRY1 25348397 N/A physical interaction ComPPI
TRAF2 CRY1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PSMC5 CRY1 25348397 N/A physical interaction ComPPI
HUWE1 CRY1 25348397 N/A physical interaction ComPPI
SNRPD3 CRY1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
WDR77 CRY1 25348397 N/A physical interaction ComPPI
CUL1 CRY1 25348397 N/A physical interaction ComPPI
SYNCRIP CRY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAH CRY1 25348397 N/A physical interaction ComPPI
YWHAE CRY1 25348397 N/A physical interaction ComPPI
JAK3 CRY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC4 CRY1 25348397 N/A physical interaction ComPPI
TCP1 CRY1 25348397 N/A physical interaction ComPPI
PER3 CRY1 10428031 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TRIM28 CRY1 25348397 N/A physical interaction ComPPI
MYCBP2 CRY1 25348397 N/A physical interaction ComPPI
USP11 CRY1 25348397 N/A physical interaction ComPPI
LRPPRC CRY1 25348397 N/A physical interaction ComPPI
PER1 CRY1 10531061 12782655 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
UBA1 CRY1 25348397 N/A physical interaction ComPPI
TGS1 CRY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MARS1 CRY1 25348397 N/A physical interaction ComPPI
BAIAP2 CRY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARNTL CRY1 10531061 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
IARS1 CRY1 25348397 N/A physical interaction ComPPI
GARS1 CRY1 25348397 N/A physical interaction ComPPI
HNRNPF CRY1 25348397 N/A physical interaction ComPPI
AP2M1 CRY1 25348397 N/A physical interaction ComPPI
IMMT CRY1 25348397 N/A physical interaction ComPPI
HNRNPH1 CRY1 25348397 N/A physical interaction ComPPI
PTBP1 CRY1 25348397 N/A physical interaction ComPPI
PPP5C CRY1 16790549 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRY2 CRY1 25348397 N/A physical interaction ComPPI
PER2 CRY1 10428031 10531061 11533252 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PSMC1 CRY1 25348397 N/A physical interaction ComPPI
KIF20B CRY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF4A2 CRY1 25348397 N/A physical interaction ComPPI
MCM3 CRY1 25348397 N/A physical interaction ComPPI
MCM4 CRY1 25348397 N/A physical interaction ComPPI
FBXL3 CRY1 25348397 N/A physical interaction ComPPI
PPP2R1B CRY1 25348397 N/A physical interaction ComPPI
CLOCK CRY1 25348397 N/A physical interaction ComPPI
EEF2 CRY1 25348397 N/A physical interaction ComPPI
TIMELESS CRY1 10428031 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CRY1 USP2 21966515 22669941 23213472 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CRY1 CSNK2B 25348397 N/A physical interaction ComPPI
CRY1 DELEC1 25348397 N/A physical interaction ComPPI
CRY1 BHLHE41 25348397 N/A physical interaction ComPPI
CRY1 NPAS2 25348397 N/A physical interaction ComPPI
CRY1 NR1D2 25348397 N/A physical interaction ComPPI
CRY1 NEDD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRY1 EEF1A1P5 25348397 N/A physical interaction ComPPI
CRY1 SDHA 25348397 N/A physical interaction ComPPI
CRY1 EIF4A1 25348397 N/A physical interaction ComPPI
CRY1 NASP 25348397 N/A physical interaction ComPPI
CRY1 CCT8 25348397 N/A physical interaction ComPPI
CRY1 USP9X 25348397 N/A physical interaction ComPPI
CRY1 ATP5F1A 25348397 N/A physical interaction ComPPI
CRY1 ALDH9A1 25348397 N/A physical interaction ComPPI
CRY1 SLC25A5 25348397 N/A physical interaction ComPPI
CRY1 CCT4 25348397 N/A physical interaction ComPPI
CRY1 MATR3 25348397 N/A physical interaction ComPPI
CRY1 MTHFD1 25348397 N/A physical interaction ComPPI
CRY1 DNAJA1 25348397 N/A physical interaction ComPPI
CRY1 ILF3 25348397 N/A physical interaction ComPPI
CRY1 PAICS 25348397 N/A physical interaction ComPPI
CRY1 RUVBL2 25348397 N/A physical interaction ComPPI
CRY1 KRT10 25348397 N/A physical interaction ComPPI
CRY1 CCT6A 25348397 N/A physical interaction ComPPI
CRY1 PSMD3 25348397 N/A physical interaction ComPPI
CRY1 MCM7 25348397 N/A physical interaction ComPPI
CRY1 EFTUD2 25348397 N/A physical interaction ComPPI
CRY1 HNRNPA3 25348397 N/A physical interaction ComPPI
CRY1 NDUFS3 25348397 N/A physical interaction ComPPI
CRY1 GMPS 25348397 N/A physical interaction ComPPI
CRY1 DARS1 25348397 N/A physical interaction ComPPI
CRY1 PPAT 25348397 N/A physical interaction ComPPI
CRY1 RPS3 25348397 N/A physical interaction ComPPI
CRY1 PABPC3 25348397 N/A physical interaction ComPPI
CRY1 FOXO1 25348397 N/A physical interaction ComPPI
CRY1 RGS20 25348397 N/A physical interaction ComPPI
PPP2R5D CRY1 25348397 N/A physical interaction ComPPI
ACLY CRY1 25348397 N/A physical interaction ComPPI
RPS14 CRY1 25348397 N/A physical interaction ComPPI
FASN CRY1 25348397 N/A physical interaction ComPPI
CRY1 COP1 11752373 18252844 24554768 27898060 N/A N/A OmniPath
CRY1 SIPA1 21511871 21511872 22577138 27898060 N/A N/A OmniPath
ARNTL CRY1 10531061 14701732 15226430 16717091 18662546 19106159 21966515 23555304 25127877 25756610 27898060 stimulant N/A OmniPath
CRY1 ARNTL 10531061 14701732 15226430 16717091 18662546 19106159 21966515 23555304 25127877 25756610 27898060 inhibition N/A OmniPath
PRKAA1 CRY1 21892142 27898060 inhibition N/A OmniPath

Visualization










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