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GENE：CTHRC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CTHRC1
FullNmae collagen triple helix repeat containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18831
EnsembleID ENSG00000164932
Uniprot Q96CG8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CTHRC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CTHRC1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CTHRC1 GO:0001649,GO:0005109,GO:0005201,GO:0005576,GO:0005581,GO:0005615,GO:0016528,GO:0017147,GO:0033687,GO:0033690,GO:0043932,GO:0045669,GO:0060071,GO:0060122,GO:0062023,GO:0090090,GO:0090103,GO:0090177

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CTHRC1 PRICKLE1 11226259 12839624 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 16604063 17030191 17127310 17244647 17430994 17884187 18497258 18606138 18851840 19020754 19379695 19565474 19853559 20006983 20093472 20215527 20457807 20579883 20930545 21087212 21316585 21380625 21397842 21572392 21640127 22017973 22949611 26192618 7641885 8655584 interaction type N/A ACSN
RACK1 CTHRC1 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 12839624 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16604063 16713974 17030191 17127310 17244647 17303408 17430994 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18606138 18851840 18953287 19020754 19151919 19366350 19379695 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20457807 20535745 20579883 20930545 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21572392 21640127 21796133 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
ROR2 CTHRC1 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 12839624 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16604063 16713974 17030191 17127310 17244647 17303408 17430994 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18606138 18851840 18953287 19020754 19151919 19366350 19379695 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20457807 20535745 20579883 20930545 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21572392 21640127 21796133 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
CTHRC1 RSPO3 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16713974 17127310 17303408 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18851840 18953287 19020754 19151919 19366350 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20535745 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21796133 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
APC2 CTHRC1 11226259 11274345 11698448 11729192 11739775 11756498 11779461 11992112 12194823 12361600 12533515 12740575 12839624 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15279786 15375164 15388793 15618519 15761148 16263762 16604063 16713974 17030191 17127310 17244647 17303408 17430994 17517963 17660363 17884187 17986005 18000759 18037882 18256687 18423981 18497258 18590585 18606138 18851840 18953287 19020754 19151919 19366350 19379695 19565474 19836308 19853559 19910923 20006983 20093472 20215527 20351293 20457807 20535745 20579883 20930545 20947020 21069266 21078818 21087212 21178402 21316585 21380625 21397842 21572392 21640127 21796133 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 27331412 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
CTHRC1 SMURF1 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 26192618 7641885 8655584 interaction type N/A ACSN
RAC1 CTHRC1 11226259 11274345 11756498 12533515 14704854 14747478 15265686 15618519 17127310 17884187 18000759 18497258 18851840 18953287 19020754 19151919 19565474 19853559 20006983 20093472 20215527 21087212 21380625 21796133 22017973 26192618 27331412 7641885 8655584 interaction type N/A ACSN
CTHRC1 DAAM1 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20351293 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN
CTHRC1 RHOA 11226259 11698448 11729192 11739775 11779461 11992112 12194823 12361600 12740575 14657501 14704854 14744429 14747478 15265686 15279786 15618519 15761148 16713974 17127310 17303408 17517963 17660363 17884187 18037882 18256687 18423981 18497258 18590585 18851840 19020754 19366350 19565474 19836308 19853559 20006983 20535745 21178402 22017973 22949611 23732914 24857661 24919149 26192618 26885855 26885856 27048821 27066895 7479854 7575488 7641885 8655584 9362522 9660866 9822605 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
AR CTHRC1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CTHRC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CTHRC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CTHRC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 CTHRC1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000521626 CTHRC1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 CTHRC1 25416803 25510669 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000260A3A CTHRC1 20371350 22012620 23446348 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 CTHRC1 25416803 26388700 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
ZDHHC17 CTHRC1 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFAP2C CTHRC1 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
VAPA CTHRC1 24234451 30021884 physical association cross-linking study IntAct
CTHRC1 FZD5 18606138 27898060 N/A N/A OmniPath
CTHRC1 FZD3 18606138 27898060 N/A N/A OmniPath
CTHRC1 FZD6 18606138 27898060 N/A N/A OmniPath

Visualization










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