GENE:FYCO1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | FYCO1 |
FullNmae | FYVE and coiled-coil domain autophagy adaptor 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:14673 |
EnsembleID | ENSG00000163820 |
Uniprot | Q9BQS8 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
FYCO1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
FYCO1 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
FYCO1 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
FYCO1 | GO:0005515,GO:0005764,GO:0005764,GO:0005770,GO:0005770,GO:0005776,GO:0005776,GO:0005794,GO:0016020,GO:0043231,GO:0046872,GO:0072383,GO:0072383,GO:1901098,GO:1901098 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
FYCO1 | hsa:79443 | path:hsa05132 | Salmonella infection - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | FYCO1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
E2F4 | FYCO1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | FYCO1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | FYCO1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | FYCO1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000508C13 | FYCO1 | N/A 15685193 | rna interference,inhibition | array technology | miRSponge |
URS0000508C13 | FYCO1 | 15685193 25416803 | mrna cleavage,inhibition | array technology,array technology,experimental interaction detection | TarBase |
URS00002C0FCB | FYCO1 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00000DDD35 | FYCO1 | 20371350 22473208 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
URS00003D5391 | FYCO1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00005651EE | FYCO1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000451A1 | FYCO1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000042E1F | FYCO1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001E0AEA | FYCO1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000600E6 | FYCO1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000544FF1 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004DA9DB | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000535FDD | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001B12A4 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001AFC71 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075A281 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000013D17D | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006FDD4 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DE669 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000005CF5F | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002152A8 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000065D58 | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000007FBA | FYCO1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000298BA3 | FYCO1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002B3783 | FYCO1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002075FA | FYCO1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PPL | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
SGF29 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
SEC23B | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
KIF5B | FYCO1 | 20562859 24234451 25348397 25855459 | physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
EMD | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
LMNA | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
GABARAPL2 | FYCO1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
MAP1LC3B | FYCO1 | 20562859 24089205 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification | ComPPI,IntAct |
BORCS6 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
RPA1 | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
XPO1 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
RPA2 | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
RPA3 | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TMPO | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
DTNA | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
TCP1 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
CCT7 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
RAF1 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
GABARAP | FYCO1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
MAP1LC3A | FYCO1 | 20562859 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
HIF1AN | FYCO1 | 24234451 25348397 29426014 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PAX6 | FYCO1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TRIM25 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
GOPC | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
KDM1A | FYCO1 | 23455924 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
CCAR1 | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
KIF23 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
IQCB1 | FYCO1 | 21565611 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SEC24B | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TCP10L | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
KLC2 | FYCO1 | 24234451 25348397 25855459 27898060 | physical association | pull down,physical interaction | ComPPI,IntAct,OmniPath |
POLDIP3 | FYCO1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MAP4 | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CYLD | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
GABARAPL1 | FYCO1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
AP5Z1 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
CCT2 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
CCT6A | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
PRMT6 | FYCO1 | 23455924 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
APP | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
CCT3 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
FOXK1 | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MOV10 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
TMPO | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
CCT6B | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
SASS6 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
TECPR1 | FYCO1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation | ComPPI,IntAct |
MAP1LC3C | FYCO1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
FYCO1 | RMC1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FYCO1 | CCZ1B | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
FYCO1 | MON1B | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FYCO1 | MLYCD | 25348397 | N/A | physical interaction | ComPPI |
FYCO1 | TRUB2 | 25348397 | N/A | physical interaction | ComPPI |
FYCO1 | DDX60 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FYCO1 | ADO | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FYCO1 | RFT1 | 25348397 | N/A | physical interaction | ComPPI |
NOL9 | FYCO1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CCDC68 | FYCO1 | 25348397 | N/A | physical interaction | ComPPI |
FYCO1 | CCZ1 | 20562859 24234451 | physical association | anti tag coimmunoprecipitation | IntAct |
FYCO1 | FYCO1 | 20562859 24234451 | physical association | anti tag coimmunoprecipitation | IntAct |
RRBP1 | FYCO1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
RAB7A | FYCO1 | 20100911 27898060 | stimulant | N/A | OmniPath |