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GENE：NPAS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NPAS2
FullNmae neuronal PAS domain protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7895
EnsembleID ENSG00000170485
Uniprot Q99743

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NPAS2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NPAS2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NPAS2 GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006357,GO:0006974,GO:0007417,GO:0009410,GO:0032922,GO:0032922,GO:0045739,GO:0045893,GO:0045893,GO:0046872,GO:0046983,GO:0051775,GO:0051879,GO:1990513,GO:1990837,GO:2000987

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NPAS2 hsa:4862 path:hsa04710 Circadian rhythm - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NPAS2 AR 17011549 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF4 NPAS2 16969126 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR NPAS2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NPAS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NPAS2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NPAS2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 NPAS2 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NPAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
KAT2B NPAS2 14645221 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 NPAS2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE NPAS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA NPAS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 NPAS2 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
NPAS2 PER3 25361965 interaction type N/A PTMCode2
PER3 NPAS2 25361965 interaction type N/A PTMCode2
NPAS2 ARNTL 25361965 interaction type N/A PTMCode2
ARNTL NPAS2 25361965 interaction type N/A PTMCode2
NPAS2 CRY2 25361965 interaction type N/A PTMCode2
CRY2 NPAS2 25361965 interaction type N/A PTMCode2
NPAS2 RXRA 25361965 interaction type N/A PTMCode2
RXRA NPAS2 25361965 interaction type N/A PTMCode2
PER2 NPAS2 25361965 interaction type N/A PTMCode2
NPAS2 PER2 25361965 interaction type N/A PTMCode2
PER1 NPAS2 25361965 interaction type N/A PTMCode2
NPAS2 PER1 25361965 interaction type N/A PTMCode2
CRY1 NPAS2 25361965 interaction type N/A PTMCode2
NPAS2 CRY1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 NPAS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 NPAS2 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
CRX NPAS2 25348397 N/A physical interaction ComPPI
RARA NPAS2 11439184 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
CREBBP NPAS2 14525934 14645221 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NCOA3 NPAS2 14525934 14645221 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EP300 NPAS2 14525934 14645221 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
KAT2B NPAS2 14525934 14645221 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
HGS NPAS2 25348397 N/A physical interaction ComPPI
HSP90AA1 NPAS2 14525934 25348397 9079689 N/A experimental interaction detection,physical interaction ComPPI,HPRD
HNRNPL NPAS2 25348397 N/A physical interaction ComPPI
TRAF4 NPAS2 25348397 N/A physical interaction ComPPI
EFS NPAS2 25348397 N/A physical interaction ComPPI
ARNTL NPAS2 11439184 14525934 25348397 9576906 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
CRY2 NPAS2 25348397 N/A physical interaction ComPPI
HESX1 NPAS2 25348397 N/A physical interaction ComPPI
RPL6 NPAS2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CLOCK NPAS2 25348397 N/A physical interaction ComPPI
ARNTL2 NPAS2 25348397 N/A physical interaction ComPPI
CRY1 NPAS2 25348397 N/A physical interaction ComPPI
INCA1 NPAS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSNK2B NPAS2 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHMT2 NPAS2 25348397 N/A physical interaction ComPPI
ARNT2 NPAS2 25348397 N/A physical interaction ComPPI
NGLY1 NPAS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RORC NPAS2 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BPIFA1 NPAS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RASSF7 NPAS2 25348397 N/A physical interaction ComPPI
RXRA NPAS2 11439184 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
HSP90AA2P NPAS2 25348397 N/A physical interaction ComPPI
NPAS2 RHOXF1 25348397 N/A physical interaction ComPPI
NPAS2 ZSCAN1 25348397 N/A physical interaction ComPPI
NPAS2 DELEC1 25348397 N/A physical interaction ComPPI
NPAS2 UBAP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NPAS2 PER1 19106159 27898060 stimulant N/A OmniPath
NPAS2 PER2 19106159 27898060 stimulant N/A OmniPath

Visualization










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