GENE：RORB
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RORB |
| FullNmae | RAR related orphan receptor B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10259 |
| EnsembleID | ENSG00000198963 |
| Uniprot | Q92753 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RORB | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RORB | GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0003700,GO:0004879,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006355,GO:0006357,GO:0007186,GO:0007601,GO:0008270,GO:0008502,GO:0030522,GO:0035881,GO:0042462,GO:0042752,GO:0045668,GO:0045892,GO:0045893,GO:0045944,GO:0046548,GO:0046549,GO:0048511,GO:0060041,GO:0071300,GO:1990837 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| RORB | hsa:6096 | path:hsa04710 | Circadian rhythm - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMARCA4 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | RORB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| UBE2I | RORB | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| BHLHE40 | RORB | 23555304 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| NRIP1 | RORB | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| PNRC2 | RORB | 25348397 | N/A | two hybrid | ComPPI |
| NCOA1 | RORB | 11689423 15604093 23975195 25348397 27898060 | N/A | physical interaction,in vitro | ComPPI,OmniPath |
| NCOA6 | RORB | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| NME1 | RORB | 25348397 | N/A | in vitro | ComPPI |
| PSMC5 | RORB | 25348397 | N/A | physical interaction | ComPPI |
| PSMC4 | RORB | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| TNNI2 | RORB | 25348397 | N/A | physical interaction | ComPPI |
| NPPA | RORB | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| PNRC1 | RORB | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| CLOCK | RORB | 25348397 | N/A | physical interaction | ComPPI |
| RORB | NRIP2 | 25348397 | N/A | in vitro,in vivo | ComPPI |
| RORB | NME2 | 25348397 | N/A | two hybrid,in vitro | ComPPI |
| RORB | RORC | 23555304 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RORB | CSNK2B | 23555304 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RORB | ARNTL | 18454201 27898060 | stimulant | N/A | OmniPath |