GENE：SERPINF1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SERPINF1 |
| FullNmae | serpin family F member 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8824 |
| EnsembleID | ENSG00000132386 |
| Uniprot | P36955 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SERPINF1 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SERPINF1 | GO:0001822,GO:0004867,GO:0005515,GO:0005576,GO:0005604,GO:0005615,GO:0005615,GO:0007614,GO:0010447,GO:0010596,GO:0010629,GO:0010951,GO:0010976,GO:0016525,GO:0016525,GO:0042470,GO:0042698,GO:0043203,GO:0046685,GO:0048471,GO:0050769,GO:0060041,GO:0060767,GO:0060770,GO:0062023,GO:0070062,GO:0071279,GO:0071300,GO:0071333,GO:0071549,GO:1901652 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SERPINF1 | hsa:5176 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SERPINF1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ESR1 | SERPINF1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | SERPINF1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | SERPINF1 | 19559773 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | SERPINF1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | SERPINF1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | SERPINF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SERPINF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SERPINF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | SERPINF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SERPINF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SERPINF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | SERPINF1 | 18971253 22115973 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | SERPINF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PARP1 | SERPINF1 | 18312852 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARA | SERPINF1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARB | SERPINF1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARG | SERPINF1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EPM2AIP1 | SERPINF1 | 24234451 25348397 25416956 25910212 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid | ComPPI,IntAct |
| SGTB | SERPINF1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SERPINF1 | CSNK2A1 | 14525934 16322471 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| SERPINF1 | MYOC | 14525934 16289162 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| SERPINF1 | MLH1 | 20706999 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| SERPINF1 | PNPLA2 | 17032652 18191271 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| SERPINF1 | LRP6 | 25348397 | N/A | physical interaction | ComPPI |
| SERPINF1 | SERPINA6 | 25348397 | N/A | physical interaction | ComPPI |
| SERPINF1 | TMEM25 | 25348397 | N/A | physical interaction | ComPPI |
| SERPINF1 | L3MBTL2 | 25348397 | N/A | physical interaction | ComPPI |
| SERPINF1 | KLHL8 | 25348397 | N/A | physical interaction | ComPPI |
| SERPINF1 | TUBA4A | 25348397 | N/A | physical interaction | ComPPI |
| SERPINF1 | HSPA5 | 25348397 | N/A | physical interaction | ComPPI |
| SERPINF1 | PTPN11 | 25348397 | N/A | physical interaction | ComPPI |
| NEDD4L | SERPINF1 | 25348397 | N/A | physical interaction | ComPPI |
| PRKACA | SERPINF1 | 15374885 21059648 27898060 | N/A | N/A | OmniPath |