GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
SP7 |
| FullNmae |
Sp7 transcription factor |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:17321 |
| EnsembleID |
ENSG00000170374 |
| Uniprot |
Q8TDD2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| SP7 |
autophagy |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| SP7 |
GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001649,GO:0001649,GO:0003677,GO:0005515,GO:0005634,GO:0005737,GO:0006357,GO:0006357,GO:0010467,GO:0014070,GO:0017151,GO:0032868,GO:0034224,GO:0045944,GO:0046872,GO:0060218,GO:0071344,GO:0071529,GO:2000738 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| YBX1 |
SP7 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| TFAP2C |
SP7 |
20629094
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
SP7 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
SP7 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
SP7 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
SP7 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
SP7 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
SP7 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| ZNF263 |
SP7 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| RUNX2 |
SP7 |
18331818
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS000001C659 |
SP7 |
19795981
25416803
|
mrna cleavage,inhibition |
quantitative reverse transcription pcr |
TarBase |
| URS0000001EB3 |
SP7 |
23827457
25416803
|
mrna cleavage,inhibition |
array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
| URS00004F4657 |
SP7 |
23886710
25416803
|
mrna cleavage,inhibition |
western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| SP7 |
MID1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| MID1 |
SP7 |
25361965
|
interaction type |
N/A |
PTMCode2 |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| CBL |
SP7 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CBLB |
SP7 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GSK3B |
SP7 |
24234451
25348397
25728276
27898060
|
colocalization,physical association |
anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy |
ComPPI,IntAct,OmniPath |
| QARS1 |
SP7 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| STUB1 |
SP7 |
25348397
|
N/A |
physical interaction |
ComPPI |
| GYS1 |
SP7 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| TRIM62 |
SP7 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| GAS8 |
SP7 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| RIOX1 |
SP7 |
19927124
27898060
|
inhibition |
N/A |
OmniPath |
| AKT1 |
SP7 |
21619873
21777568
27898060
|
stimulant |
N/A |
OmniPath |
Visualization